Additional Information
Book Details
Abstract
Get the most from your study time...and experience a realistic USMLE simulation! Rapid Review Pathology, by Edward F. Goljan, MD, makes it easy for you to master all of the pathology material covered on the USMLE Step 1. It combines an updated outline-format review of key concepts and hundreds of full-color images and margin notes, PLUS more than 400 USMLE-style online questions! Get all the practice you need to succeed on the USMLE!
- Consult this title on your favorite e-reader , conduct rapid searches, and adjust font sizes for optimal readability. Compatible with Kindle®, nook®, and other popular devices.
- Review all the information you need to know quickly and easily with a user-friendly, two-color outline format that includes High-Yield Margin Notes and Key Points.
- Practice for the USMLE with the included access to online USMLE sample questions and full rationales.
- Profit from the guidance of Dr. Edward Goljan, a well-known author of medical review books, who reviewed and edited every question.
- Visualize key pathologic concepts and conditions with over 1,000 full-color images, completely reviewed and updated for this new edition.
- Take a timed or practice USMLE test, access rationales for why each answer is right or wrong, and link to other Rapid Review books you have purchased online at www.StudentConsult.com.
Table of Contents
| Section Title | Page | Action | Price |
|---|---|---|---|
| Front Cover | cover | ||
| Inside Front Cover | ifc1 | ||
| Robbins family ad | i | ||
| Rapid Review Series | ii | ||
| Rapid Review Pathology, 4/e | iii | ||
| Copyright Page | iv | ||
| Dedication | v | ||
| Preface | vi | ||
| Acknowledgments | vii | ||
| Table Of Contents | ix | ||
| 1 Diagnostic Testing | 1 | ||
| I. Purpose of Laboratory Tests | 1 | ||
| II. Operating Characteristics of Laboratory Tests | 2 | ||
| III. Predictive Value of Positive and Negative Test Results | 2 | ||
| IV. Creating Highly Sensitive and Specific Tests | 3 | ||
| V. Variables Affecting Laboratory Test Results | 3 | ||
| 2 Cell Injury | 8 | ||
| I. Tissue Hypoxia | 8 | ||
| II. Free Radical Cell Injury | 17 | ||
| III. Injury to Cellular Organelles (Fig. 2-8) | 19 | ||
| IV. Intracellular Accumulations | 22 | ||
| V. Adaptation to Cell Injury: Growth Alterations | 25 | ||
| VI. Cell Death | 29 | ||
| 3 Inflammation and Repair | 36 | ||
| I. Acute Inflammation (AI) | 36 | ||
| II. Chronic Inflammation (CI) | 44 | ||
| III. Tissue Repair | 46 | ||
| IV. Laboratory Findings Associated with Inflammation | 51 | ||
| 4 Immunopathology | 56 | ||
| I. Cells of the Immune System | 56 | ||
| II. Major Histocompatibility Complex | 59 | ||
| III. Hypersensitivity Reactions (HSRs) | 61 | ||
| IV. Transplantation Immunology | 69 | ||
| V. Autoimmune Disease | 72 | ||
| VI. Immunodeficiency Disorders | 81 | ||
| VII. Amyloidosis | 90 | ||
| 5 Water, Electrolyte, Acid-Base, and Hemodynamic Disorders | 93 | ||
| I. Water and Electrolyte Disorders | 93 | ||
| II. Acid-Base Disorders | 109 | ||
| III. Edema | 115 | ||
| IV. Thrombosis | 117 | ||
| V. Embolism | 120 | ||
| VI. Shock | 122 | ||
| 6 Genetic and Developmental Disorders | 126 | ||
| I. Mutations | 126 | ||
| II. Mendelian Disorders | 128 | ||
| III. Chromosomal Disorders | 137 | ||
| IV. Other Patterns of Inheritance | 144 | ||
| V. Disorders of Sex Differentiation | 146 | ||
| VI. Congenital Anomalies | 149 | ||
| VII. Perinatal and Infant Disorders | 153 | ||
| VIII. Diagnosis of Genetic and Developmental Disorders | 155 | ||
| IX. Aging | 156 | ||
| 7 Environmental Pathology | 158 | ||
| I. Chemical Injury | 158 | ||
| II. Physical Injury | 163 | ||
| III. Radiation Injury | 172 | ||
| 8 Nutritional Disorders | 174 | ||
| I. Nutrient and Energy Requirements in Humans | 174 | ||
| II. Dietary Fuels | 174 | ||
| III. Protein-Energy Malnutrition | 176 | ||
| IV. Eating Disorders and Obesity | 179 | ||
| V. Fat-Soluble Vitamins | 182 | ||
| VI. Water-Soluble Vitamins | 187 | ||
| VII. Trace Elements | 191 | ||
| VIII. Mineral and Electrolyte Deficiency and Excess (Table 8-6) | 193 | ||
| IX. Dietary Fiber | 193 | ||
| X. Special Diets | 194 | ||
| 9 Neoplasia | 195 | ||
| I. Nomenclature | 195 | ||
| II. Properties of Benign and Malignant Tumors | 197 | ||
| III. Cancer Epidemiology | 203 | ||
| IV. Carcinogenesis | 207 | ||
| V. Carcinogenic Agents | 209 | ||
| VI. Clinical Oncology | 211 | ||
| 10 Vascular Disorders | 215 | ||
| I. Lipoprotein Disorders | 215 | ||
| II. Arteriosclerosis | 220 | ||
| III. Vessel Aneurysms | 223 | ||
| IV. Venous System Disorders | 226 | ||
| V. Lymphatic Disorders | 229 | ||
| VI. Vascular Tumors and Tumor-like Conditions (Table 10-2; Fig. 10-13) | 230 | ||
| VII. Vasculitic Disorders | 230 | ||
| VIII. Hypertension | 233 | ||
| 11 Heart Disorders | 239 | ||
| I. Cardiac Physical Diagnosis | 239 | ||
| II. Ventricular Hypertrophy | 239 | ||
| III. Congestive Heart Failure (CHF) | 243 | ||
| IV. Ischemic Heart Disease (IHD) | 247 | ||
| V. Congenital Heart Disease (CHD) | 255 | ||
| VI. Acquired Valvular Heart Disease | 261 | ||
| VII. Myocardial and Pericardial Disorders | 271 | ||
| VIII. Cardiomyopathy | 274 | ||
| IX. Tumors of the Heart | 278 | ||
| 12 Red Blood Cell Disorders | 279 | ||
| I. Erythropoiesis | 279 | ||
| II. Complete Blood Cell Count and Other Studies | 281 | ||
| III. Microcytic Anemias | 285 | ||
| IV. Macrocytic Anemias | 295 | ||
| V. Normocytic Anemias: Corrected Reticulocyte Count or Index <3% (see Table 12-5) | 301 | ||
| VI. Normocytic Anemias: Corrected Reticulocyte Count >3% (see Table 12-5) | 303 | ||
| 13 White Blood Cell Disorders | 318 | ||
| I. Benign Qualitative White Blood Cell Disorders | 318 | ||
| II. Benign Quantitative WBC Disorders | 319 | ||
| III. Acute and Chronic Leukemias | 323 | ||
| IV. Neoplastic Myeloid Disorders | 324 | ||
| V. Lymphoid Leukemias | 330 | ||
| 14 Lymphoid Tissue Disorders | 334 | ||
| I. Lymphadenopathy | 334 | ||
| II. Non-Hodgkin Lymphoma (NHL) | 339 | ||
| III. Hodgkin Lymphoma (HL) | 341 | ||
| IV. Langerhans Cell Histiocytoses (Histiocytosis X) | 343 | ||
| V. Mast Cell Disorders | 344 | ||
| VI. Plasma Cell Dyscrasias (Monoclonal Gammopathies) | 345 | ||
| VII. Spleen Disorders | 347 | ||
| 15 Hemostasis Disorders | 351 | ||
| I. Normal Hemostasis and Hemostasis Testing | 351 | ||
| II. Platelet Disorders | 358 | ||
| III. Coagulation Disorders | 361 | ||
| IV. Fibrinolytic Disorders | 364 | ||
| V. Summary of Laboratory Test Results in Hemostasis Disorders | 364 | ||
| VI. Thrombosis Syndromes | 364 | ||
| 16 Immunohematology Disorders | 367 | ||
| I. ABO Blood Group Antigens | 367 | ||
| II. Rh and Non-Rh Antigen Systems | 368 | ||
| III. Blood Transfusion Therapy | 369 | ||
| IV. Hemolytic Disease of the Newborn (HDN) | 372 | ||
| 17 Upper and Lower Respiratory Disorders | 377 | ||
| I. Symptoms and Signs of Respiratory Disease | 377 | ||
| II. Alveolar-Arterial (a-a) Gradient | 377 | ||
| III. Upper Airway Disorders | 380 | ||
| IV. Atelectasis | 382 | ||
| V. Acute Lung Injury | 384 | ||
| VI. Pulmonary Infections | 385 | ||
| VII. Vascular Lung Lesions | 394 | ||
| VIII. Restrictive Lung Diseases | 397 | ||
| IX. Chronic Obstructive Pulmonary Disease (COPD) | 403 | ||
| X. Lung Tumors | 411 | ||
| XI. Mediastinum and Pleural Disorders | 415 | ||
| 18 Gastrointestinal Disorders | 419 | ||
| I. Oral Cavity and Salivary Gland Disorders | 419 | ||
| II. Esophageal Disorders | 425 | ||
| III. Stomach Disorders | 433 | ||
| IV. Small Bowel and Large Bowel Disorders | 438 | ||
| V. Anorectal Disorders | 464 | ||
| 19 Hepatobiliary and Pancreatic Disorders | 467 | ||
| I. Laboratory Evaluation of Liver Cell Injury | 467 | ||
| II. Viral Hepatitis | 467 | ||
| III. Other Inflammatory Liver Disorders | 473 | ||
| IV. Circulatory Disorders of the Liver | 477 | ||
| V. Alcohol-Related and Drug- and Chemical-Induced Liver Disorders | 479 | ||
| VI. Obstructive (Cholestatic) Liver Disease | 479 | ||
| VII. Cirrhosis | 481 | ||
| VIII. Liver Tumors and Tumor-like Disorders | 489 | ||
| IX. Gallbladder and Biliary Tract Disease | 491 | ||
| X. Pancreatic Disorders | 495 | ||
| 20 Kidney Disorders | 500 | ||
| I. Renal Function Overview | 500 | ||
| II. Important Laboratory Findings in Renal Disease | 500 | ||
| III. Renal Function Tests | 501 | ||
| IV. Clinical Anatomy of the Kidney | 506 | ||
| V. Congenital Disorders and Cystic Diseases of the Kidneys | 507 | ||
| VI. Glomerular Diseases | 507 | ||
| VII. Disorders Affecting Tubules and Interstitium | 515 | ||
| VIII. Chronic Renal Failure (CRF) | 520 | ||
| IX. Vascular Diseases of the Kidney | 521 | ||
| X. Obstructive Disorders of the Kidney | 523 | ||
| XI. Tumors of the Kidney and Renal Pelvis | 525 | ||
| 21 Lower Urinary Tract and Male Reproductive Disorders | 528 | ||
| I. Common Ureteral Disorders | 528 | ||
| II. Urinary Bladder Diseases | 528 | ||
| III. Urethral Diseases | 533 | ||
| IV. Penis Diseases | 533 | ||
| V. Testis, Scrotal Sac, and Epididymis Diseases | 534 | ||
| VI. Prostate Diseases | 539 | ||
| VII. Male Hypogonadism | 543 | ||
| VIII. Male Infertility | 544 | ||
| IX. Erectile Dysfunction | 545 | ||
| 22 Female Reproductive Disorders and Breast Disorders | 547 | ||
| I. Sexually Transmitted Diseases and Other Genital Infections | 547 | ||
| II. Vulva Disorders | 547 | ||
| III. Vagina Disorders | 550 | ||
| IV. Cervix Disorders | 552 | ||
| V. Reproductive Physiology and Selected Hormone Disorders | 555 | ||
| VI. Uterine Disorders | 564 | ||
| VII. Fallopian Tube Disorders | 568 | ||
| VIII. Ovarian Disorders | 570 | ||
| IX. Gestational Disorders | 573 | ||
| X. Breast Disorders | 580 | ||
| 23 Endocrine Disorders | 588 | ||
| I. Overview of Endocrine Disease | 588 | ||
| II. Hypothalamus Disorders | 589 | ||
| III. Pineal Gland Disorders | 590 | ||
| IV. Pituitary Gland Disorders | 590 | ||
| V. Thyroid Gland Disorders | 594 | ||
| VI. Parathyroid Gland Disorders | 605 | ||
| VII. Adrenal Gland Disorders | 612 | ||
| VIII. Islet Cell Tumors (Table 23-10) | 621 | ||
| IX. Diabetes Mellitus (DM) | 621 | ||
| X. Polyglandular Deficiency Syndromes | 628 | ||
| XI. Hypoglycemia | 628 | ||
| 24 Musculoskeletal and Soft Tissue Disorders | 630 | ||
| I. Bone Disorders | 630 | ||
| II. Joint Disorders | 637 | ||
| III. Muscle Disorders | 649 | ||
| IV. Soft Tissue Disorders | 654 | ||
| V. Selected Orthopedic Disorders | 658 | ||
| 25 Skin Disorders | 659 | ||
| I. Skin Histology and Terminology | 659 | ||
| II. Selected Viral Disorders | 659 | ||
| III. Selected Bacterial Disorders | 664 | ||
| IV. Selected Fungal Disorders | 667 | ||
| V. Selected Parasitic and Arthropod Disorders | 671 | ||
| VI. Melanocytic Disorders | 673 | ||
| VII. Benign Epithelial Tumors | 676 | ||
| VIII. Premalignant and Malignant Epithelial Tumors | 678 | ||
| IX. Selected Skin Disorders | 680 | ||
| X. Selected Skin Disorders in Newborns | 686 | ||
| XI. Selected Hair and Nail Disorders | 687 | ||
| 26 Nervous System and Special Sensory Disorders | 690 | ||
| I. Cerebral Edema, Pseudotumor Cerebri (Idiopathic Intracranial Hypertension), Herniation and Hydrocephalus | 690 | ||
| II. Developmental Disorders | 695 | ||
| III. Head Trauma | 697 | ||
| IV. Cerebrovascular Diseases | 699 | ||
| V. CNS Infections | 706 | ||
| VI. Demyelinating Disorders | 708 | ||
| VII. Degenerative Disorders | 715 | ||
| VIII. Toxic and Metabolic Disorders | 719 | ||
| IX. CNS Tumors | 720 | ||
| X. Peripheral Nervous System Disorders | 722 | ||
| XI. Selected Eye Disorders | 725 | ||
| XII. Selected Ear Disorders | 725 | ||
| Formulas for Calculations of Acid-Base Disorders | 732 | ||
| Index | 734 | ||
| A | 734 | ||
| B | 738 | ||
| C | 739 | ||
| D | 743 | ||
| E | 745 | ||
| F | 746 | ||
| G | 747 | ||
| H | 748 | ||
| I | 751 | ||
| J | 752 | ||
| K | 752 | ||
| L | 753 | ||
| M | 754 | ||
| N | 757 | ||
| O | 758 | ||
| P | 759 | ||
| Q | 763 | ||
| R | 763 | ||
| S | 764 | ||
| T | 767 | ||
| U | 769 | ||
| V | 769 | ||
| W | 771 | ||
| X | 771 | ||
| Y | 771 | ||
| Z | 771 | ||
| Clinical Key | 773 | ||
| Inside Back Cover | ibc1 |