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Pharmacology and the Nursing Process - E-Book

Pharmacology and the Nursing Process - E-Book

Linda Lane Lilley | Shelly Rainforth Collins | Julie S. Snyder

(2014)

Additional Information

Book Details

Abstract

With its colorful, user-friendly format, Pharmacology and the Nursing Process, 7th Edition provides students with all the pharmacology information they need — and no more than they need — to administer drugs safely and effectively. Increased emphasis on the nursing process and prioritization focuses on the most essential assessments, nursing diagnoses, interventions, and evaluations. Thoroughly updated drug information is clear and concise, highlighting the most commonly used drugs, and includes a unique focus on safety-oriented QSEN competencies. Hundreds of full-color illustrations show how drugs work in the body and depict key steps in drug administration. Written by expert pharmacology educators and clinicians, this bestselling textbook employs innovative, practical learning aids to help your students prepare for success on the NCLEX® Examination and in nursing practice.

    • Focus on need-to-know information provides the most essential drug information for safe, effective clinical practice.
    • Focus on the nursing process and prioritization helps you apply the nursing process to all aspects of drug therapy, from assessment to nursing diagnoses, interventions, and evaluation/outcome criteria.
    • UNIQUE! Illustrated Study Skills Tips include practical advice on time management, note taking, study techniques, and test-taking strategies.
    • Special boxes and tables highlight evidence-based practice, dosages, pharmacokinetics, laboratory values related to drug therapy, preventing medication errors, cultural implications, lifespan considerations, herbal therapies, and legal and ethical principles.
    • Nearly 300 full-color illustrations and the Photo Atlas of Drug Administration show how drugs work in the body and depict key steps in drug administration by various routes.
    • NCLEX® Examination−style review questions are included in every chapter, with at least one alternate-format item per chapter and more than 40 new dosage calculation questions.
    • Drug profiles highlight the pharmacokinetics and unique variations of commonly used drugs.
    • Case studies promote clinical reasoning skills related to nursing pharmacology.
    • Patient Teaching Tips include key points to convey to patients, their families, and their caregivers.

    Table of Contents

    Section Title Page Action Price
    Front Cover Cover
    IFC\r IFC
    BRIEF CONTENTS i
    ABOUT THE AUTHORS ii
    Pharmacology and the Nursing Process iii
    Copyright iv
    CONTRIBUTORS TO TEACHING/LEARNING RESOURCES v
    REVIEWERS vi
    PREFACE vii
    ORGANIZATION vii
    NEW TO THIS EDITION viii
    ADDITIONAL TEACHING/LEARNING FEATURES viii
    SUPPLEMENTAL RESOURCES ix
    ACKNOWLEDGMENTS ix
    WE WELCOME YOUR FEEDBACK x
    PART 1 -\rPharmacology Basics 1
    CHAPTER 1 - The Nursing Process And Drug Therapy 6
    OVERVIEW OF THE NURSING PROCESS 7
    ASSESSMENT 7
    NURSING DIAGNOSES 9
    PLANNING 10
    IMPLEMENTATION 11
    EVALUATION 15
    Chapter 2 - Pharmacologic Principles 17
    OVERVIEW 19
    PHARMACEUTICS 21
    PHARMACOKINETICS 22
    PHARMACODYNAMICS 30
    PHARMACOTHERAPEUTICS 31
    PHARMACOGNOSY 35
    PHARMACOECONOMICS 35
    TOXICOLOGY 35
    SUMMARY 36
    Chapter 3 - Lifespan Considerations 37
    DRUG THERAPY DURING PREGNANCY 38
    DRUG THERAPY DURING BREASTFEEDING 38
    CONSIDERATIONS FOR NEONATAL AND PEDIATRIC PATIENTS 39
    CONSIDERATIONS FOR ELDERLY PATIENTS 42
    NURSING PROCESS 44
    Chapter 4 - Cultural, Legal, and Ethical Considerations 50
    CULTURAL CONSIDERATIONS 51
    LEGAL CONSIDERATIONS 54
    ETHICAL CONSIDERATIONS 59
    NURSING PROCESS 60
    Chapter 5 - Medication Errors: Preventing and Responding 64
    GENERAL IMPACT OF ERRORS ON PATIENTS 65
    MEDICATION ERRORS 65
    ISSUES CONTRIBUTING TO ERRORS 66
    PREVENTING, RESPONDING TO, REPORTING, AND DOCUMENTING MEDICATION ERRORS: A NURSING PERSPECTIVE 68
    OTHER ETHICAL ISSUES 71
    SUMMARY 72
    Chapter 6 - Patient Education and Drug Therapy 74
    ASSESSMENT OF LEARNING NEEDS RELATED TO DRUG THERAPY 75
    NURSING DIAGNOSES RELATED TO LEARNING NEEDS AND DRUG THERAPY 77
    PLANNING RELATED TO LEARNING NEEDS AND DRUG THERAPY 77
    IMPLEMENTATION RELATED TO PATIENT EDUCATION AND DRUG THERAPY 77
    EVALUATION OF PATIENT LEARNING RELATED TO DRUG THERAPY 81
    SUMMARY 81
    Chapter 7 - Over-the-Counter Drugs and Herbal and Dietary Supplements 84
    OVER-THE-COUNTER DRUGS 85
    HERBALS AND DIETARY SUPPLEMENTS 87
    Chapter 8 - Gene Therapy and Pharmacogenomics 94
    BASIC PRINCIPLES OF GENETIC INHERITANCE 95
    DISCOVERY, STRUCTURE, AND FUNCTION OF DNA 96
    GENE THERAPY 97
    PHARMACOGENETICS AND PHARMACOGENOMICS 98
    SUMMARY 100
    Chapter 9 - Photo Atlas of Drug Administration 102
    PREPARING FOR DRUG ADMINISTRATION 102
    ENTERAL DRUGS 104
    PARENTERAL DRUGS 110
    TOPICAL DRUGS 128
    ILLUSTRATION CREDITS 136
    PART 2 - Drugs Affecting the Central Nervous System 137
    Chapter 10 - Analgesic Drugs 139
    ANATOMY, PHYSIOLOGY, AND PATHOPHYSIOLOGY OVERVIEW 141
    TREATMENT OF PAIN IN SPECIAL SITUATIONS 144
    PHARMACOLOGY OVERVIEW 147
    OPIOID DRUGS 147
    NONOPIOID AND MISCELLANEOUS ANALGESICS 155
    Chapter 11 - General and Local Anesthetics 169
    ANATOMY, PHYSIOLOGY, AND PATHOPHYSIOLOGY OVERVIEW 170
    PHARMACOLOGY OVERVIEW 170
    GENERAL ANESTHETICS 170
    DRUGS FOR MODERATE SEDATION 173
    LOCAL ANESTHETICS 174
    NEUROMUSCULAR BLOCKING DRUGS 177
    Chapter 12 - Central Nervous System Depressants and Muscle Relaxants 188
    ANATOMY, PHYSIOLOGY, AND PATHOPHYSIOLOGY OVERVIEW 189
    PHYSIOLOGY OF SLEEP 189
    PHARMACOLOGY OVERVIEW 190
    BENZODIAZEPINES AND MISCELLANEOUS HYPNOTIC DRUGS 190
    BARBITURATES 193
    MUSCLE RELAXANTS 196
    Chapter 13 - Central Nervous System Stimulants and Related Drugs 203
    ANATOMY, PHYSIOLOGY, AND PATHOPHYSIOLOGY OVERVIEW 204
    ATTENTION DEFICIT HYPERACTIVITY DISORDER 205
    NARCOLEPSY 205
    OBESITY 205
    MIGRAINE 205
    ANALEPTIC-RESPONSIVE RESPIRATORY DEPRESSION SYNDROMES 205
    PHARMACOLOGY OVERVIEW 206
    DRUGS FOR ATTENTION DEFICIT HYPERACTIVITY DISORDER AND NARCOLEPSY 206
    ANOREXIANTS 208
    ANTIMIGRAINE DRUGS 209
    DRUGS FOR SPECIFIC RESPIRATORY DEPRESSION SYNDROMES: ANALEPTICS 212
    Chapter 14 - Antiepileptic Drugs 219
    ANATOMY, PHYSIOLOGY, AND PATHOPHYSIOLOGY OVERVIEW 220
    EPILEPSY 220
    PHARMACOLOGY OVERVIEW 221
    ANTIEPILEPTIC DRUGS 221
    Chapter 15 - Antiparkinson Drugs 237
    ANATOMY, PHYSIOLOGY, AND PATHOPHYSIOLOGY OVERVIEW 238
    PATHOPHYSIOLOGY OF PARKINSON’S DISEASE 238
    TREATMENT OF PARKINSON’S DISEASE 239
    PHARMACOLOGY OVERVIEW 240
    MONOAMINE OXIDASE INHIBITORS 240
    DRUG PROFILES 242
    DOPAMINE MODULATOR 243
    DRUG PROFILE 243
    CATECHOL ORTHO-METHYLTRANSFERASE INHIBITORS 243
    DRUG PROFILE 244
    NONDOPAMINE DOPAMINE RECEPTOR AGONISTS 244
    DRUG PROFILES 244
    DOPAMINE REPLACEMENT DRUGS 245
    ANTICHOLINERGIC DRUGS 246
    Chapter 16 - Psychotherapeutic Drugs 253
    ANATOMY, PHYSIOLOGY, AND PATHOPHYSIOLOGY OVERVIEW 254
    PHARMACOLOGY OVERVIEW 256
    ANXIOLYTIC DRUGS 256
    MOOD-STABILIZING DRUGS 259
    ANTIDEPRESSANT DRUGS 259
    TRICYCLIC ANTIDEPRESSANTS 261
    MONOAMINE OXIDASE INHIBITORS 264
    SECOND-GENERATION ANTIDEPRESSANTS 265
    ANTIPSYCHOTIC DRUGS 267
    Chapter 17 - Substance Abuse 281
    ANATOMY, PHYSIOLOGY, AND PATHOPHYSIOLOGY OVERVIEW 282
    PHARMACOLOGY OVERVIEW 283
    OPIOIDS 283
    STIMULANTS 284
    DEPRESSANTS 285
    ALCOHOL 287
    NICOTINE 289
    PART 3 -\rDrugs Affecting the Autonomic Nervous System 296
    Chapter 18 - Adrenergic Drugs 298
    ANATOMY, PHYSIOLOGY, AND PATHOPHYSIOLOGY OVERVIEW 299
    SYMPATHETIC NERVOUS SYSTEM 299
    PHARMACOLOGY OVERVIEW 300
    ADRENERGIC DRUGS 300
    Chapter 19 - Adrenergic-Blocking Drugs 312
    OBJECTIVES 312
    ANATOMY, PHYSIOLOGY, AND PATHOPHYSIOLOGY OVERVIEW 313
    PHARMACOLOGY OVERVIEW 313
    ALPHA BLOCKERS 313
    DRUG PROFILES 316
    BETA BLOCKERS 316
    DRUG PROFILES 318
    NURSING PROCESS 319
    Anchor 76 322
    Anchor 77 323
    Chapter 20 - Cholinergic Drugs 324
    ANATOMY, PHYSIOLOGY, AND PATHOPHYSIOLOGY OVERVIEW 325
    PARASYMPATHETIC NERVOUS SYSTEM 325
    PHARMACOLOGY OVERVIEW 325
    CHOLINERGIC DRUGS 325
    Chapter 21 - Cholinergic-Blocking Drugs 334
    ANATOMY, PHYSIOLOGY, AND PATHOPHYSIOLOGY OVERVIEW 335
    PARASYMPATHETIC NERVOUS SYSTEM 335
    PHARMACOLOGY OVERVIEW 335
    CHOLINERGIC-BLOCKING DRUGS 335
    PART 4 -\rDrugs Affecting the\rCardiovascular and\rRenal Systems 343
    CHAPTER 22 - ANTIHYPERTENSIVE DRUGS 347
    ANATOMY, PHYSIOLOGY, AND PATHOPHYSIOLOGY OVERVIEW 348
    PHARMACOLOGY OVERVIEW 349
    REVIEW OF AUTONOMIC NEUROTRANSMISSION 350
    ADRENERGIC DRUGS 350
    ANGIOTENSIN-CONVERTING ENZYME (ACE) INHIBITORS 353
    ANGIOTENSIN II RECEPTOR BLOCKERS 356
    CALCIUM CHANNEL BLOCKERS 357
    DIURETICS 357
    VASODILATORS 357
    MISCELLANEOUS ANTIHYPERTENSIVE DRUGS 359
    Chapter 23 - Antianginal Drugs 368
    ANATOMY, PHYSIOLOGY, AND PATHOPHYSIOLOGY OVERVIEW 369
    PHARMACOLOGY OVERVIEW 369
    NITRATES AND NITRITES 370
    BETA BLOCKERS 372
    CALCIUM CHANNEL BLOCKERS 374
    MISCELLANEOUS ANTIANGINAL DRUG 376
    SUMMARY OF ANTIANGINAL PHARMACOLOGY 376
    Chapter 24 - Heart Failure Drugs 382
    ANATOMY, PHYSIOLOGY, AND PATHOPHYSIOLOGY OVERVIEW 383
    PHARMACOLOGY OVERVIEW 384
    ANGIOTENSIN-CONVERTING ENZYME INHIBITORS 384
    ANGIOTENSIN II RECEPTOR BLOCKERS 385
    BETA BLOCKERS 385
    ALDOSTERONE ANTAGONISTS 385
    MISCELLANEOUS HEART FAILURE DRUGS 385
    B-TYPE NATRIURETIC PEPTIDE 386
    PHOSPHODIESTERASE INHIBITORS 387
    CARDIAC GLYCOSIDES 387
    Chapter 25 - Antidysrhythmic Drugs 396
    ANATOMY, PHYSIOLOGY, AND PATHOPHYSIOLOGY OVERVIEW 397
    DYSRHYTHMIAS AND NORMAL CARDIAC ELECTROPHYSIOLOGY 397
    PHARMACOLOGY OVERVIEW 403
    ANTIDYSRHYTHMIC DRUGS 403
    Chapter 26 - Coagulation Modifier Drugs 418
    ANATOMY, PHYSIOLOGY, AND PATHOPHYSIOLOGY OVERVIEW 419
    PHARMACOLOGY OVERVIEW 421
    ANTICOAGULANTS 421
    ANTIPLATELET DRUGS 427
    THROMBOLYTIC DRUGS 430
    ANTIFIBRINOLYTIC DRUGS 432
    Chapter 27 - Antilipemic Drugs 443
    ANATOMY, PHYSIOLOGY, AND PATHOPHYSIOLOGY OVERVIEW 444
    LIPIDS AND LIPID ABNORMALITIES 444
    ATHEROSCLEROTIC PLAQUE FORMATION 446
    CHOLESTEROL AND CORONARY HEART DISEASE 446
    HYPERLIPIDEMIAS AND TREATMENT GUIDELINES 446
    PHARMACOLOGY OVERVIEW 448
    HYDROXYMETHYLGLUTARYL–COENZYME A REDUCTASE INHIBITORS 448
    BILE ACID SEQUESTRANTS 450
    NIACIN 451
    FIBRIC ACID DERIVATIVES 452
    Chapter 28 - Diuretic Drugs 459
    ANATOMY, PHYSIOLOGY, AND PATHOPHYSIOLOGY OVERVIEW 460
    PHARMACOLOGY OVERVIEW 461
    CARBONIC ANHYDRASE INHIBITORS 461
    LOOP DIURETICS 462
    OSMOTIC DIURETICS 464
    POTASSIUM-SPARING DIURETICS 465
    THIAZIDES AND THIAZIDE-LIKE DIURETICS 466
    Chapter 29 - Fluids and Electrolytes 473
    ANATOMY, PHYSIOLOGY, AND PATHOPHYSIOLOGY OVERVIEW 474
    PHARMACOLOGY OVERVIEW 476
    CRYSTALLOIDS 476
    COLLOIDS 478
    BLOOD PRODUCTS 479
    PHYSIOLOGY OF ELECTOLYTE BALANCE 480
    POTASSIUM 480
    SODIUM 482
    PART 5 - Drugs Affecting the\rEndocrine System 491
    Chapter 30 - Pituitary Drugs 493
    ANATOMY, PHYSIOLOGY AND PATHOPHYSIOLOGY OVERVIEW 494
    ENDOCRINE SYSTEM 494
    PHARMACOLOGY OVERVIEW 494
    PITUITARY DRUGS 494
    Chapter 31 - Thyroid and Antithyroid Drugs 501
    ANATOMY, PHYSIOLOGY, AND PATHOPHYSIOLOGY OVERVIEW 502
    THYROID FUNCTION 502
    PATHOPHYSIOLOGY OF HYPOTHYROIDISM 502
    PATHOPHYSIOLOGY OF HYPERTHYROIDISM 502
    PHARMACOLOGY OVERVIEW 502
    THYROID REPLACEMENT DRUGS 502
    ANTITHYROID DRUGS 504
    Chapter 32 - Antidiabetic Drugs 510
    ANATOMY, PHYSIOLOGY, AND PATHOPHYSIOLOGY OVERVIEW 511
    PANCREAS 511
    PATHOPHYSIOLOGY OF DIABETES MELLITUS 512
    PHARMACOLOGY OVERVIEW 516
    BIGUANIDE 520
    SULFONYLUREAS 521
    GLINIDES 521
    THIAZOLIDINEDIONES (GLITAZONES) 522
    ALPHA-GLUCOSIDASE INHIBITORS 522
    DIPEPTIDYL PEPTIDASE IV (DPP-IV) INHIBITORS 523
    AMYLIN AGONISTS 524
    INCRETIN MIMETICS 524
    Chapter 33 - Adrenal Drugs 533
    ANATOMY, PHYSIOLOGY, AND PATHOPHYSIOLOGY OVERVIEW 534
    ADRENAL SYSTEM 534
    PHARMACOLOGY OVERVIEW 535
    ADRENAL DRUGS 535
    Chapter 34 - Women’s Health Drugs 543
    ANATOMY, PHYSIOLOGY, AND PATHOPHYSIOLOGY OVERVIEW 544
    FEMALE REPRODUCTIVE FUNCTIONS 544
    PHARMACOLOGY OVERVIEW 545
    ESTROGENS 545
    PROGESTINS 549
    FERTILITY DRUGS 554
    UTERINE STIMULANTS 555
    DRUGS FOR PRETERM LABOR MANAGEMENT 557
    Chapter 35 - Men’s Health Drugs 564
    ANATOMY, PHYSIOLOGY, AND PATHOPHYSIOLOGY OVERVIEW 565
    MALE REPRODUCTIVE SYSTEM 565
    PHARMACOLOGY OVERVIEW 565
    ANDROGENS AND OTHER DRUGS PERTAINING TO MEN’S HEALTH 565
    PART 6 - Drugs Affecting the Respiratory System 573
    Chapter 36 - Antihistamines, Decongestants, Antitussives, and Expectorants 575
    ANATOMY, PHYSIOLOGY, AND PATHOPHYSIOLOGY OVERVIEW 576
    PHARMACOLOGY OVERVIEW 576
    ANTIHISTAMINES 576
    DECONGESTANTS 580
    ANTITUSSIVES 582
    EXPECTORANTS 584
    Chapter 37 - Respiratory Drugs 588
    ANATOMY, PHYSIOLOGY, AND PATHOPHYSIOLOGY OVERVIEW 589
    PATHOPHYSIOLOGY OF DISEASES OF THE RESPIRATORY SYSTEM 589
    TREATMENT OF DISEASES OF THE LOWER RESPIRATORY TRACT 591
    PHARMACOLOGY OVERVIEW 591
    BETA-ADRENERGIC AGONISTS 591
    ANTICHOLINERGICS 594
    XANTHINE DERIVATIVES 595
    LEUKOTRIENE RECEPTOR ANTAGONISTS 596
    CORTICOSTEROIDS 597
    PHOSPHODIESTERASE-4 INHIBITOR 600
    MONOCLONAL ANTIBODY ANTIASTHMATIC 600
    PART 7 - Antiinfective and\rAntiinflammatory Drugs 607
    Chapter 38 - Antibiotics Part 1 609
    ANATOMY, PHYSIOLOGY, AND PATHOPHYSIOLOGY OVERVIEW 610
    MICROBIAL INFECTION 610
    PHARMACOLOGY OVERVIEW 612
    SULFONAMIDES 614
    PENICILLINS 616
    CEPHALOSPORINS 619
    CARBAPENEMS 623
    MONOBACTAMS 623
    Chapter 39 - Antibiotics Part 2 633
    PATHOPHYSIOLOGY OF RESISTANT INFECTIONS 634
    PHARMACOLOGY OVERVIEW 635
    AMINOGLYCOSIDES 635
    QUINOLONES 638
    MISCELLANEOUS ANTIBIOTICS 640
    Chapter 40 - Antiviral Drugs 650
    ANATOMY, PHYSIOLOGY, AND PATHOPHYSIOLOGY OVERVIEW 651
    GENERAL PRINCIPLES OF VIROLOGY 651
    OVERVIEW OF VIRAL ILLNESSES AND THEIR TREATMENT 653
    HERPES SIMPLEX VIRUS AND VARICELLA-ZOSTER VIRUS INFECTIONS 654
    PHARMACOLOGY OVERVIEW 655
    ANTIVIRALS (NON-HIV) 655
    PATHOPHYSIOLOGY OVERVIEW 658
    HIV INFECTION AND AIDS 658
    PHARMACOLOGY OVERVIEW 662
    DRUGS USED TO TREAT HIV INFECTION 662
    PATHOPHYSIOLOGY OVERVIEW 666
    OTHER VIRAL INFECTIONS 666
    Chapter 41 - Antitubercular Drugs 672
    ANATOMY, PHYSIOLOGY, AND PATHOPHYSIOLOGY OVERVIEW 673
    PATHOPHYSIOLOGY OF TUBERCULOSIS 673
    PHARMACOLOGY OVERVIEW 674
    ANTITUBERCULAR DRUGS 674
    Chapter 42 - Antifungal Drugs 682
    ANATOMY, PHYSIOLOGY, AND PATHOPHYSIOLOGY OVERVIEW 683
    FUNGAL INFECTIONS 683
    PHARMACOLOGY OVERVIEW 683
    ANTIFUNGAL DRUGS 683
    Chapter 43 - Antimalarial, Antiprotozoal, and Anthelmintic Drugs 692
    ANATOMY, PHYSIOLOGY, AND PATHOPHYSIOLOGY OVERVIEW 693
    PATHOPHYSIOLOGY OF MALARIA 693
    PHARMACOLOGY OVERVIEW 693
    ANTIMALARIAL DRUGS 693
    PATHOPHYSIOLOGY OVERVIEW 698
    OTHER PROTOZOAL INFECTIONS 698
    PHARMACOLOGY OVERVIEW 698
    ANTIPROTOZOAL DRUGS 698
    PATHOPHYSIOLOGY OVERVIEW 700
    HELMINTHIC INFECTIONS 700
    PHARMACOLOGY OVERVIEW 701
    ANTHELMINTIC DRUGS 701
    Chapter 44 - Antiinflammatory and Antigout Drugs 706
    ANATOMY, PHYSIOLOGY, AND PATHOPHYSIOLOGY OVERVIEW 707
    PHARMACOLOGY OVERVIEW 707
    NONSTEROIDAL ANTIINFLAMMATORY DRUGS 707
    ANTIGOUT DRUGS 713
    PART 8 - Immune and Biologic Modifiers\rand Chemotherapeutic Drugs 720
    CHAPTER 45 - ANTINEOPLASTIC DRUGS PART 1: CANCER OVERVIEW AND CELL CYCLE–SPECIFIC DRUGS 722
    ANATOMY, PHYSIOLOGY, AND PATHOPHYSIOLOGY OVERVIEW 724
    ETIOLOGY OF CANCER 725
    PHARMACOLOGY OVERVIEW 728
    ANTIMETABOLITES 730
    MITOTIC INHIBITORS 734
    ALKALOID TOPOISOMERASE II INHIBITORS 735
    TOPOISOMERASE I INHIBITORS 736
    ANTINEOPLASTIC ENZYMES 738
    Chapter 46 - Antineoplastic Drugs Part 2: Cell Cycle–Nonspecific and Miscellaneous Drugs 748
    PHARMACOLOGY OVERVIEW 749
    ALKYLATING DRUGS 749
    DRUG PROFILES 752
    CYTOTOXIC ANTIBIOTICS 752
    Chapter 47 - Biologic Response–Modifying and Antirheumatic Drugs 762
    ANATOMY, PHYSIOLOGY, AND PATHOPHYSIOLOGY OVERVIEW 764
    OVERVIEW OF IMMUNOMODULATORS 764
    IMMUNE SYSTEM 764
    PHARMACOLOGY OVERVIEW 766
    HEMATOPOIETIC DRUGS 766
    INTERFERONS 768
    MONOCLONAL ANTIBODIES 770
    INTERLEUKINS AND RELATED DRUGS 774
    MISCELLANEOUS IMMUNOMODULATING DRUGS 776
    PATHOPHYSIOLOGY OVERVIEW 776
    RHEUMATOID ARTHRITIS 776
    PHARMACOLOGY OVERVIEW 777
    DISEASE-MODIFYING ANTIRHEUMATIC ARTHRITIS DRUGS 777
    Chapter 48 - Immunosuppressant Drugs 784
    ANATOMY, PHYSIOLOGY, AND PATHOPHYSIOLOGY DISEASE OVERVIEW 785
    IMMUNE SYSTEM 785
    PHARMACOLOGY OVERVIEW 785
    IMMUNOSUPPRESSANT DRUGS 785
    Chapter 49 - Immunizing Drugs and Biochemical Terrorism 795
    ANATOMY, PHYSIOLOGY, AND PATHOPHYSIOLOGY OVERVIEW 797
    IMMUNITY AND IMMUNIZATION 797
    PHARMACOLOGY OVERVIEW 799
    IMMUNIZING DRUGS 799
    ANTHRAX 808
    PART 9 - Drugs Affecting the\rGastrointestinal System\rand Nutrition 813
    CHAPTER 50 - ACID-CONTROLLING DRUGS 815
    ANATOMY, PHYSIOLOGY, AND PATHOPHYSIOLOGY OVERVIEW 816
    ACID-RELATED PATHOPHYSIOLOGY 816
    PHARMACOLOGY OVERVIEW 818
    ANTACIDS 818
    H2 RECEPTOR ANTAGONISTS 820
    PROTON PUMP INHIBITORS 822
    MISCELLANEOUS ACID-CONTROLLING DRUGS 823
    Chapter 51 - Bowel Disorder Drugs 829
    ANATOMY, PHYSIOLOGY, AND PATHOPHYSIOLOGY OVERVIEW 830
    PHARMACOLOGY OVERVIEW 830
    ANTIDIARRHEALS 830
    LAXATIVES 833
    DRUGS FOR IRRITABLE BOWEL SYNDROME 838
    Chapter 52 - Antiemetic and Antinausea Drugs 844
    NAUSEA AND VOMITING 845
    PHARMACOLOGY OVERVIEW 846
    ANTIEMETIC DRUGS 846
    Chapter 53 - Vitamins and Minerals 856
    ANATOMY, PHYSIOLOGY AND PATHOPHYSIOLOGY OVERVIEW 857
    PHARMACOLOGY OVERVIEW 857
    VITAMIN A 859
    VITAMIN D 861
    VITAMIN E 863
    VITAMIN K 863
    VITAMIN B1 865
    VITAMIN B2 865
    VITAMIN B3 866
    VITAMIN B6 867
    VITAMIN B12 867
    VITAMIN C 869
    CALCIUM 869
    MAGNESIUM 871
    PHOSPHORUS 872
    ZINC 873
    Chapter 54 - Anemia Drugs 877
    ANATOMY, PHYSIOLOGY, AND PATHOPHYSIOLOGY OVERVIEW 878
    ERYTHROPOIESIS 878
    TYPES OF ANEMIA 878
    PHARMACOLOGY OVERVIEW 880
    ERYTHROPOIESIS STIMULATING AGENTS 880
    IRON 880
    FOLIC ACID 883
    OTHER ANEMIA DRUGS 884
    Chapter 55 - Nutritional Supplements 888
    ANATOMY, PHYSIOLOGY, AND PATHOPHYSIOLOGY OVERVIEW 889
    PHARMACOLOGY OVERVIEW 890
    PERIPHERAL TOTAL PARENTERAL NUTRITION 892
    CENTRAL TOTAL PARENTERAL NUTRITION 893
    TRACE ELEMENTS 895
    PART 10 -\rDermatologic, Ophthalmic, and Otic Drugs 899
    CHAPTER 56 - DERMATOLOGIC DRUGS 901
    ANATOMY, PHYSIOLOGY, AND PATHOPHYSIOLOGY OVERVIEW 902
    PHARMACOLOGY OVERVIEW 903
    GENERAL ANTIBACTERIAL DRUGS 904
    ANTIACNE DRUGS 905
    ANTIFUNGAL DRUGS 906
    ANTIVIRAL DRUGS 907
    TOPICAL ANESTHETICS 908
    TOPICAL ANTIPRURITICS AND ANTIINFLAMMATORIES 908
    ANTIPSORIATIC DRUGS 909
    MISCELLANEOUS DERMATOLOGIC DRUGS 909
    Chapter 57 - Ophthalmic Drugs 916
    ANATOMY, PHYSIOLOGY, AND PATHOPHYSIOLOGY OVERVIEW 917
    LACRIMAL GLANDS 919
    LAYERS OF THE EYE 919
    PATHOPHYSIOLOGY OF GLAUCOMA 920
    PHARMACOLOGY OVERVIEW 921
    CHOLINERGIC DRUGS (MIOTICS) 921
    SYMPATHOMIMETICS (MYDRIATICS) 923
    BETA-ADRENERGIC BLOCKERS 925
    CARBONIC ANHYDRASE INHIBITORS 926
    OSMOTIC DIURETICS 927
    PROSTAGLANDIN AGONISTS 927
    Chapter 58 - Otic Drugs 937
    ANATOMY, PHYSIOLOGY, AND PATHOPHYSIOLOGY OVERVIEW 937
    PHARMACOLOGY OVERVIEW 938
    TREATMENT OF EAR DISORDERS 938
    ANTIBACTERIAL AND ANTIFUNGAL OTIC DRUGS 939
    EARWAX EMULSIFIERS 939
    Appendix - Pharmaceutical Abbreviations 943
    CASE STUDY PHOTO CREDITS 944
    INDEX 945
    EVIDENCE-BASED PRACTICE 974
    PATIENT-CENTERED CARE: CULTURAL IMPLICATIONS 974
    PATIENT-CENTERED CARE: LIFESPAN CONSIDERATIONS FOR THE ELDERLY PATIENT 974
    PATIENT-CENTERED CARE: LIFESPAN CONSIDERATIONS FOR THE PEDIATRIC PATIENT 974
    SAFETY: HERBAL THERAPIES AND DIETARY SUPPLEMENTS 974
    SAFETY: LABORATORY VALUES RELATEDTO DRUG THERAPY 975
    SAFETY AND QUALITY IMPROVEMENT: PREVENTING MEDICATION ERRORS 975
    TEAMWORK AND COLLABORATION: LEGAL AND ETHICAL PRINCIPLES 975
    ABBREVIATIONS FOR DIAGNOSTICAND LABORATORY TESTS 975
    BIBLIOGRAPHY 976
    CHAPTER 1 976
    CHAPTER 2 976
    CHAPTER 3 976
    CHAPTER 4 977
    CHAPTER 5 977
    CHAPTER 6 978
    CHAPTER 7 978
    CHAPTER 8 979
    CHAPTER 9 979
    CHAPTER 10 980
    CHAPTER 11 981
    CHAPTER 12 981
    CHAPTER 13 981
    CHAPTER 14 981
    CHAPTER 15 982
    CHAPTER 16 982
    CHAPTER 17 983
    CHAPTER 18 983
    CHAPTER 19 983
    CHAPTER 20 983
    CHAPTER 21 983
    CHAPTER 22 984
    CHAPTER 23 984
    CHAPTER 24 984
    CHAPTER 25 985
    CHAPTER 26 985
    CHAPTER 27 985
    CHAPTER 28 986
    CHAPTER 29 986
    CHAPTER 30 986
    CHAPTER 31 986
    CHAPTER 32 986
    CHAPTER 33 987
    CHAPTER 34 987
    CHAPTER 35 987
    CHAPTER 36 987
    CHAPTER 37 987
    CHAPTER 38 988
    CHAPTER 39 988
    CHAPTER 40 988
    CHAPTER 41 988
    CHAPTER 42 988
    CHAPTER 43 989
    CHAPTER 44 989
    CHAPTER 45 989
    CHAPTER 46 989
    CHAPTER 47 989
    CHAPTER 48 989
    CHAPTER 49 990
    CHAPTER 50 990
    CHAPTER 51 990
    CHAPTER 52 990
    CHAPTER 53 991
    CHAPTER 54 991
    CHAPTER 55 991
    CHAPTER 56 991
    CHAPTER 57 991
    CHAPTER 58 991