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The Massachusetts Eye and Ear Infirmary Illustrated Manual of Ophthalmology E-Book

The Massachusetts Eye and Ear Infirmary Illustrated Manual of Ophthalmology E-Book

Neil J. Friedman | Peter K. Kaiser | Roberto Pineda II

(2014)

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Book Details

Abstract

The Massachusetts Eye and Ear Infirmary Illustrated Manual of Ophthalmology is the must-have medical reference book for the ever-changing field of ophthalmology. Thoroughly updated to include the latest advances in the field, the fourth edition of this renowned manual features high-quality color images and an intuitive design for easy comprehension and reference. Ideal for ophthalmic practitioners and allied health professionals alike, this indispensable resource is your comprehensive guide for the speedy diagnosis and treatment of the most common eye disorders.

  • Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability.
  • Accurately diagnose problems through the support of full-color photographs and real case studies.
  • Rapidly locate key information with a highly templated format that includes chapters organized anatomically, not by ophthalmic subspecialty, in addition to key boxes and highlighted emergency management boxes.

  • Apply the latest knowledge and techniques in the diagnosis and treatment of ocular disease, including anti-VEGF therapy for retina disorders; optical coherence tomography and high-resolution imaging modalities; new corneal and refractive surgical approaches; advances in uveitis, glaucoma, neuro-ophthalmology; and more.
  • Stay abreast of the most recent spectral domain OCT with numerous scans included throughout the book.
  • Quickly address critical situations with highlighted emergency management boxes, as well as bonus appendices that provide a wealth of supplemental information helpful for the non-specialist, including guidance on the basics in examination methods, differential diagnosis, common medications, measurements and more.
  • Identify subtleties and nuances by examining over 800 full-color illustrations depicting a complete range of clinical disorders, imaging and testing methods, and surgical techniques, as well as brand-new videos of eye movement examination.
  • Access the videos at Expert Consult.

 


Table of Contents

Section Title Page Action Price
Front Cover Cover
The Massachusetts Eye and Ear Infirmary Illustrated Manual of Ophthalmology iii
Copyright iv
Contents v
Video Table of Contents ix
Preface xi
Contributors xii
Acknowledgments xiii
Figure Courtesy Lines xiv
Introduction xvii
Chapter 1: Orbit 1
Trauma 1
Blunt Trauma 1
Orbital Contusion 1
Orbital Hemorrhage/Orbital Compartment Syndrome 2
Orbital Fractures 3
Orbital floor (blow-out) fracture 3
Pediatric floor fracture 4
Medial wall (nasoethmoidal) fracture 4
Orbital roof fracture 5
Orbital apex fracture 5
Tripod fracture 5
Le Fort fractures 5
Penetrating Trauma 6
Intraorbital Foreign Body 6
Globe Subluxation 7
Definition 7
Etiology 7
Mechanism 7
Epidemiology 7
Symptoms 7
Signs 7
Evaluation 7
Prognosis 8
Carotid–Cavernous and Dural Sinus Fistulas 8
Definition 8
Chapter 2: Ocular Motility and Cranial Nerves 33
Strabismus 33
Definition 33
Phoria 33
Tropia 33
Esotropia 33
Exotropia 33
Hypertropia 33
Hypotropia 34
Etiology 34
Symptoms 34
Signs 34
Differential Diagnosis 34
Evaluation 34
Prognosis 35
Horizontal Strabismus 35
Esotropia 35
Infantile Esotropia 35
Accommodative Esotropia 36
Refractive 36
Nonrefractive 36
Mixed 36
Acquired Nonaccommodative Esotropia and Other Forms of Esotropia 37
Cyclical esotropia 38
Exotropia 38
Basic Exotropia 38
Convergence Insufficiency 38
Pseudodivergence Excess 39
True Divergence Excess 39
A-, V-, and X-Patterns 39
A-pattern 39
V-pattern 40
X-pattern 40
Vertical Strabismus 40
Brown's Syndrome (Superior Oblique Tendon Sheath Syndrome) 40
Dissociated Strabismus Complex: Dissociated Vertical Deviation, Dissociated Horizontal Deviation, Dissociated Torsional Dev... 41
Monocular Elevation Deficiency (Double Elevator Palsy) 42
Type 1 42
Type 2 42
Type 3 42
Miscellaneous Strabismus 43
Duane's Retraction Syndrome 43
Type 1 43
Type 2 43
Type 3 43
Möbius Syndrome 44
Restrictive Strabismus 44
Congenital Fibrosis Syndrome 44
Generalized Fibrosis (Autosomal Dominant [AD]>Autosomal Recessive [AR]>Idiopathic) 44
Congenital Fibrosis of Inferior Rectus (Sporadic or Familial) 44
Strabismus Fixus (Sporadic) 45
Vertical Retraction Syndrome 45
Congenital Unilateral Fibrosis (sporadic) 45
Nystagmus 45
Definition 45
Etiology 45
Congenital Nystagmus 45
Afferent or sensory deprivation 45
Efferent or motor 45
Latent 45
Spasmus nutans 46
Acquired Nystagmus 46
Convergence–retraction 46
Dissociated or disconjugate 46
Downbeat 46
Drug-induced 46
Gaze-evoked 46
Periodic alternating 46
See-saw 47
Upbeat 47
Vestibular 47
Physiologic Nystagmus 47
Symptoms 47
Signs 47
Differential Diagnosis 47
Evaluation 47
Prognosis 48
Third Cranial Nerve Palsy 48
Definition 48
Etiology 49
Nuclear 49
Fascicular 49
Subarachnoid Space 49
Intracavernous Space 49
Orbital Space 49
Symptoms 49
Signs 49
Differential Diagnosis 50
Evaluation 50
Prognosis 51
Fourth Cranial Nerve Palsy 51
Definition 51
Etiology 51
Nuclear 52
Fascicular 52
Subarachnoid Space 52
Intracavernous Space 52
Symptoms 52
Signs 52
Differential Diagnosis 52
Evaluation 52
Prognosis 54
Sixth Cranial Nerve Palsy 54
Definition 54
Etiology 54
Nuclear 54
Fascicular 54
Subarachnoid Space 55
Petrous Space 55
Intracavernous Space 55
Symptoms 55
Signs 55
Differential Diagnosis 55
Evaluation 56
Prognosis 56
Multiple Cranial Nerve Palsies 56
Definition 56
Etiology 56
Brain Stem 56
Subarachnoid Space 56
Cavernous Sinus Syndrome 57
Orbital Apex Syndrome 57
Symptoms 58
Signs 58
Differential Diagnosis 58
Evaluation 58
Prognosis 58
Chronic Progressive External Ophthalmoplegia (CPEO) 59
Definition 59
Etiology 59
Kearns–Sayre Syndrome (Mitochondrial DNA) 59
Mitochondrial Encephalopathy, Lactic Acidosis, and Stroke-Like Episodes (Mitochondrial DNA) 59
Myoclonic Epilepsy and Ragged Red Fibers (Mitochondrial DNA) 59
Myotonic Dystrophy (Autosomal Dominant) 59
Oculopharyngeal Muscular Dystrophy (Autosomal Dominant) 59
Symptoms 59
Signs 59
Differential Diagnosis 60
Evaluation 60
Prognosis 60
Horizontal Motility Disorders 61
Definition 61
Internuclear Ophthalmoplegia 61
One-and-a-Half Syndrome 61
Other 62
Etiology 62
Symptoms 62
Signs 62
Differential Diagnosis 62
Evaluation 63
Prognosis 63
Vertical Motility Disorders 63
Definition 63
Progressive Supranuclear Palsy (Steele–Richardson–Olszewski Syndrome) 63
Chapter 3: Lids, Lashes, and Lacrimal System 67
Eyelid Trauma 67
Contusion 67
Abrasion 68
Avulsion 68
Upper Lid Defects 69
Lower Lid Defects 69
Laceration 69
Eyelid Infections 71
Blepharitis and Meibomitis 71
Definition 71
Etiology 71
Epidemiology 72
Symptoms 72
Signs 72
Anterior Blepharitis 72
Meibomitis 72
Differential Diagnosis 72
Evaluation 72
Prognosis 73
Herpes Simplex Virus 73
Herpes Zoster Virus 74
Molluscum Contagiosum 75
Demodicosis 76
Phthiriasis or Pediculosis 76
Leprosy 77
Eyelid Inflammations 77
Chalazion or Hordeolum (Stye) 77
Definition 77
Chalazion 77
Hordeolum 77
Symptoms 77
Signs 77
Differential Diagnosis 78
Evaluation 78
Prognosis 78
Contact Dermatitis 78
Definition 78
Symptoms 78
Signs 78
Differential Diagnosis 79
Evaluation 79
Prognosis 80
Blepharochalasis 80
Madarosis 80
Definition 80
Etiology 80
Local 80
Systemic 80
Symptoms 80
Signs 80
Evaluation 80
Prognosis 81
Vitiligo and Poliosis 81
Acne Rosacea 82
Definition 82
Etiology 82
Symptoms 82
Signs 82
Evaluation 82
Prognosis 83
Eyelid Malpositions 83
Ptosis 83
Definition 83
Etiology 83
Aponeurotic (Involutional) 83
Mechanical 83
Myogenic 83
Neurogenic 84
Congenital 84
Symptoms 85
Signs 85
Differential Diagnosis 85
Evaluation 85
Prognosis 86
Dermatochalasis 86
Ectropion 87
Definition 87
Etiology 87
Cicatricial 87
Congenital 87
Inflammatory 87
Involutional 87
Mechanical 87
Paralytic 87
Symptoms 87
Signs 88
Evaluation 88
Prognosis 89
Entropion 89
Definition 89
Etiology 89
Cicatricial 89
Congenital 89
Involutional 90
Spastic 90
Symptoms 90
Signs 90
Differential Diagnosis 90
Evaluation 90
Prognosis 91
Blepharospasm 91
Definition 91
Essential Blepharospasm 91
Meige's Syndrome 91
Symptoms 91
Chapter 4: Conjunctiva and Sclera 129
Trauma 129
Foreign Body 129
Laceration 129
Open Globe 129
Subconjunctival Hemorrhage 132
Telangiectasia 133
Definition 133
Symptoms 133
Signs 133
Differential Diagnosis 133
Evaluation 133
Chapter 5: Cornea 173
Trauma 173
Abrasion 173
Birth Trauma 174
Burn 175
Foreign Body 176
Laceration 177
Recurrent Erosion 178
Peripheral Ulcerative Keratitis 178
Definition 178
Etiology 178
Marginal Keratolysis 178
Mooren's Ulcer 178
Type I 178
Type II 178
Staphylococcal Marginal Keratitis 178
Symptoms 179
Signs 179
Marginal Keratolysis 179
Mooren's Ulcer 179
Staphylococcal Marginal Keratitis 180
Differential Diagnosis 180
Evaluation 180
Prognosis 181
Contact-Lens-Related Problems 181
Definition 181
Rigid Lenses 181
Hard 181
Gas-permeable 182
Soft Lenses 182
Daily wear 182
Extended wear 182
Symptoms 183
Signs and management 183
Corneal Abrasion 183
Corneal Hypoxia 183
Acute 183
Chronic 183
Contact-Lens-Related Dendritic Keratitis 183
Contact Lens Solution Hypersensitivity or Toxicity 183
Corneal Neovascularization 183
Corneal Warpage 184
Damaged Contact Lens 185
Deposits on Contact Lens 185
Giant Papillary Conjunctivitis 185
Infectious Keratitis 186
Sterile Corneal Infiltrates 186
Poor Fit (Loose) 186
Poor Fit (Light) 186
Superior Limbic Keratoconjunctivitis 186
Superficial Punctate Keratitis 186
Evaluation 187
Prognosis 187
Miscellaneous 187
Definitions 187
Dellen 187
Exposure Keratopathy 187
Filamentary Keratitis 188
Keratic Precipitates 188
Superficial Punctate Keratitis 189
Thygeson's Superficial Punctate Keratitis 189
Symptoms 190
Signs 190
Differential Diagnosis 190
Evaluation 190
Prognosis 190
Corneal Edema 191
Definition 191
Etiology 191
Symptoms 191
Signs 191
Differential Diagnosis 191
Chapter 6: Anterior Chamber 233
Primary Angle-Closure Glaucoma 233
Definition 233
Etiology/mechanism 233
Pupillary Block 233
Plateau Iris Syndrome (Without Pupillary Block) 233
Epidemiology 233
Symptoms 233
Acute Angle-Closure 233
Subacute Angle-Closure 234
Chronic Angle-Closure 234
Signs 234
Acute Angle-Closure 234
Subacute and Chronic Angle-Closure 234
Evaluation 234
Prognosis 236
Secondary Angle-Closure Glaucoma 236
Definition 236
Etiology/mechanism 236
With Pupillary Block 236
Without Pupillary Block 236
Posterior ``pushing´´ mechanism 236
Anterior ``pulling´´ mechanism 236
Symptoms 236
Acute Angle-Closure 236
Chronic Angle-Closure 236
Signs 237
Acute Angle-Closure 237
Chronic Angle-Closure 237
Evaluation 237
Prognosis 238
Hypotony 238
Definition 238
Etiology 238
Increased Outflow (Excessive Drainage of Aqueous or Vitreous Fluid) 238
Decreased Production (Ciliary Body Shutdown) 238
Symptoms 238
Signs 238
Evaluation 239
Prognosis 239
Hyphema 240
Definition 240
Etiology 240
Symptoms 240
Signs 240
Differential Diagnosis 241
Evaluation 241
Prognosis 241
Cells and Flare 241
Definition 241
Cells 242
Flare 242
Etiology 242
Symptoms 242
Signs 242
Differential Diagnosis 242
Evaluation 242
Prognosis 243
Hypopyon 243
Definition 243
Etiology 243
Symptoms 243
Signs 243
Differential Diagnosis 243
Evaluation 244
Prognosis 244
Endophthalmitis 244
Definition 244
Etiology 244
Postoperative (70%) 244
Acute postoperative (<6 weeks after surgery) 244
Delayed postoperative (>6 weeks after surgery) 244
Conjunctival filtering bleb associated 244
Posttraumatic (20%) 244
Endogenous (2–15%) 245
Epidemiology 245
Symptoms 245
Signs 245
Differential Diagnosis 245
Evaluation 246
Prognosis 248
Anterior Uveitis (Iritis, Iridocyclitis) 248
Definition 248
Etiology 248
Infectious Anterior Uveitis 248
Herpes Simplex and Herpes Zoster Ophthalmicus 248
Lyme Disease 248
Syphilis 248
Tuberculosis 248
Noninfectious Anterior Uveitis 249
Nongranulomatous 249
Idiopathic (acute) 249
HLA-B27 associated (acute) 249
Seronegative spondyloarthropathies (acute) 249
Ankylosing spondylitis 249
Reiter's syndrome (reactive arthritis) 249
Inflammatory bowel disease 249
Psoriatic arthritis 249
Whipple's disease 249
Behçet's disease (acute) 250
Glaucomatocyclitic crisis (Posner–Schlossman syndrome) (acute) 250
Kawasaki's disease (acute) 250
Drugs (acute) 250
Interstitial nephritis (acute) 250
Other autoimmune disease (acute and chronic) 250
Juvenile rheumatoid arthritis (JRA, acute and chronic) 250
Fuchs' heterochromic iridocyclitis (chronic) 250
Postoperative or trauma (acute or chronic) 251
Granulomatous 251
Autoimmune 251
HLA associations (located on chromosome 6) 251
Symptoms 251
Signs 251
Differential Diagnosis 252
Evaluation 252
Prognosis 254
Uveitis–Glaucoma–Hyphema Syndrome 255
Definition 255
Symptoms 255
Signs 255
Differential Diagnosis 255
Evaluation 255
Prognosis 255
Chapter 7: Iris and Pupils 257
Trauma 257
Definition 257
Angle Recession 258
Cyclodialysis 258
Iridodialysis 258
Sphincter Tears 259
Symptoms 260
Signs 260
Differential Diagnosis 260
Evaluation 260
Chapter 8: Lens 293
Congenital Anomalies 293
Definition 293
Coloboma 293
Lenticonus 294
Anterior 294
Posterior 294
Lentiglobus 294
Microspherophakia 294
Mittendorf Dot 295
Symptoms 295
Signs 295
Differential Diagnosis 295
Evaluation 295
Prognosis 295
Congenital Cataract 296
Definition 296
Capsular 296
Lamellar or Zonular 296
Lenticular or Nuclear 296
Polar 297
Sutural 297
Etiology 297
Hereditary or Syndromes 297
Without chromosomal abnormalities 297
With chromosomal abnormalities 298
Other syndromes 298
Intrauterine Infections 298
Congenital rubella syndrome 298
Congenital varicella syndrome 298
Metabolic 298
Galactosemia 298
Lowe's oculocerebrorenal syndrome (X-linked) 298
Alport's syndrome (AD) 298
Other metabolic diseases 298
Ocular Disorders 298
Other 299
Epidemiology 299
Symptoms 299
Signs 299
Differential Diagnosis 299
Evaluation 299
Prognosis 300
Acquired Cataract 300
Definition 300
Cortical Degeneration 300
Spokes and vacuoles 300
Mature cataract 300
Morgagnian cataract 301
Hypermature cataract 301
Nuclear Sclerosis 301
Subcapsular Cataract 302
Anterior subcapsular 302
Posterior subcapsular 302
Etiology 303
Senile 303
Systemic Disease 303
Diabetes mellitus 303
Hypocalcemia 303
Myotonic dystrophy 303
Wilsons disease 304
Others 304
Other Eye Diseases 304
Toxic 304
Trauma 305
Epidemiology 305
Symptoms 305
Signs 305
Differential Diagnosis 305
Evaluation 306
Prognosis 306
Posterior Capsular Opacification 306
Definition 306
Epidemiology 306
Etiology 306
Symptoms 306
Signs 306
Evaluation 307
Chapter 9: Vitreous 319
Amyloidosis 319
Definition 319
Symptoms 319
Signs 319
Differential Diagnosis 320
Evaluation 320
Prognosis 320
Asteroid Hyalosis 320
Persistent Hyperplastic Primary Vitreous (Persistent Fetal Vasculature Syndrome) 321
Definition 321
Symptoms 321
Signs 322
Differential Diagnosis 322
Evaluation 322
Prognosis 323
Posterior Vitreous Detachment 323
Definition 323
Epidemiology 323
Symptoms 323
Signs 323
Differential Diagnosis 324
Evaluation 324
Prognosis 325
Synchesis Scintillans 325
Vitreous Hemorrhage 325
Definition 325
Etiology 325
Symptoms 325
Signs 325
Differential Diagnosis 326
Evaluation 326
Prognosis 326
Vitritis 326
Chapter 10: Retina and Choroid 327
Trauma 328
Choroidal Rupture 328
Commotio Retinae (Berlin's Edema) 328
Purtscher's Retinopathy 329
Traumatic Retinal Holes 330
Giant Retinal Tear 330
Avulsion of Vitreous Base 330
Oral Tear 330
Preoral Tear 330
Retinal Dialysis 330
Chorioretinitis Sclopeteria 331
Hemorrhages 331
Preretinal Hemorrhage 331
Intraretinal Hemorrhage 331
Flame-Shaped Hemorrhage 332
Dot/Blot Hemorrhage 332
Roth Spot 333
Subretinal Hemorrhage 333
Cotton-Wool Spot 333
Branch Retinal Artery Occlusion 334
Definition 334
Etiology 334
Epidemiology 334
Symptoms 334
Signs 334
Differential Diagnosis 335
Evaluation 335
Prognosis 336
Central Retinal Artery Occlusion 336
Definition 336
Etiology 336
Epidemiology 336
Symptoms 337
Signs 337
Differential Diagnosis 338
Evaluation 338
Prognosis 339
Ophthalmic Artery Occlusion 339
Definition 339
Etiology 339
Epidemiology 339
Symptoms 339
Signs 339
Differential Diagnosis 340
Evaluation 340
Prognosis 340
Branch Retinal Vein Occlusion 340
Definition 340
Nonischemic (64%) 340
Ischemic 340
Etiology 340
Epidemiology 341
Symptoms 341
Signs 341
Differential Diagnosis 341
Evaluation 341
Prognosis 342
Central/Hemiretinal Vein Occlusion 343
Definition 343
Nonischemic/Perfused (67%) 343
Ischemic/Nonperfused 343
Etiology 343
Epidemiology 343
Symptoms 343
Signs 343
Differential Diagnosis 343
Evaluation 345
Prognosis 346
Venous Stasis Retinopathy 346
Ocular Ischemic Syndrome 347
Definition 347
Etiology 347
Epidemiology 347
Symptoms 347
Signs 347
Differential Diagnosis 347
Evaluation 347
Prognosis 348
Retinopathy of Prematurity 348
Definition 348
Epidemiology 348
Symptoms 348
Signs 348
Stage 1 348
Stage 2 348
Stage 3 348
Stage 4 348
Stage 5 349
Zone 1 349
Zone 2 349
Zone 3 349
``Plus´´ Disease 349
Differential Diagnosis 349
Evaluation 349
Prognosis 350
Coats' Disease/Leber's Miliary Aneurysms 350
Stage 1 351
Stage 2 351
Stage 3 351
Stage 4 351
Stage 5 351
Familial Exudative Vitreoretinopathy and Norrie's Disease (X-Linked Recessive) 352
Incontinentia Pigmenti (X-Linked Dominant) 352
Eales' Disease 352
Macular Telangiectasia (Idiopathic Juxtafoveal/Perifoveal Telangiectasia) 353
Type 1A (Unilateral Congenital Parafoveal Telangiectasia) 353
Type 1B (Unilateral Idiopathic Parafoveal Telangiectasia) 353
Type 2 (Bilateral Acquired Parafoveal Telangiectasia) 354
Type 3 (Bilateral Perifoveal Telangiectasis with Capillary Obliteration) 354
Retinopathies Associated with Blood Abnormalities 355
Retinopathy of Anemia 355
Leukemic Retinopathy 355
Sickle Cell Retinopathy 356
Stage I 356
Stage II 356
Stage III 357
Stage IV 357
Stage V 357
Diabetic Retinopathy 358
Definition 358
Epidemiology 358
Insulin-Dependent Diabetes (Type I) 358
Non-Insulin-Dependent Diabetes (Type II) 358
Symptoms 358
Signs 358
Nonproliferative Diabetic Retinopathy 358
Proliferative Diabetic Retinopathy 360
Differential Diagnosis 361
Evaluation 361
Prognosis 363
Hypertensive Retinopathy 363
Definition 363
Epidemiology 363
Symptoms 363
Signs 363
Keith Wagener Barker grades 363
Proposed classification scheme 364
Differential Diagnosis 364
Evaluation 364
Prognosis 364
Toxemia of Pregnancy 364
Acquired Retinal Arterial Macroaneurysm 365
Radiation Retinopathy 366
Definition 366
Etiology 366
Epidemiology 366
Symptoms 366
Signs 366
Differential Diagnosis 367
Evaluation 367
Prognosis 367
Age-Related Macular Degeneration 367
Definition 367
Epidemiology 367
Nonexudative (Dry) Macular Degeneration 368
Symptoms 368
Signs 369
Differential Diagnosis 369
Evaluation 369
Prognosis 370
Exudative (Wet) Macular Degeneration 370
Symptoms 370
Signs 372
Differential Diagnosis 372
Evaluation 372
Prognosis 374
Retinal Angiomatous Proliferation 374
Polypoidal Choroidal Vasculopathy 375
Myopic Degeneration/Pathologic Myopia 377
Angioid Streaks 379
Definition 379
Etiology 379
Symptoms 379
Signs 380
Differential Diagnosis 380
Evaluation 381
Prognosis 381
Central Serous Chorioretinopathy 381
Definition 381
Epidemiology 381
Symptoms 381
Signs 381
Differential Diagnosis 382
Evaluation 382
Prognosis 383
Cystoid Macular Edema 383
Definition 383
Etiology 383
Symptoms 384
Signs 384
Differential Diagnosis 384
Evaluation 384
Prognosis 385
Macular Hole 385
Definition 385
Etiology 385
Epidemiology 385
Symptoms 385
Signs 386
Stage 0 386
Stage 1 386
Stage 2 386
Stage 3 386
Stage 4 386
Differential Diagnosis 387
Evaluation 387
Prognosis 388
Vitreomacular Adhesion and Traction 388
Epiretinal Membrane/Macular Pucker 388
Definition 388
Etiology 388
Epidemiology 389
Symptoms 389
Signs 389
Differential Diagnosis 391
Evaluation 391
Prognosis 391
Myelinated Nerve Fibers 391
Solar/Photic Retinopathy 392
Toxic (Drug) Maculopathies 392
Aminoglycosides (Gentamicin/Tobramicin/Amikacin) 392
Canthaxanthine (Orobronze) 392
Chloroquine (Aralen)/Hydroxychloroquine (Plaquenil) 393
Chlorpromazine (Thorazine) 395
Deferoxamine (Desferal) 395
Interferon α 395
Methoxyflurane (Penthrane) 395
Niacin 396
Quinine (Quinamm) 396
Sildenafil (Viagra) 397
Tadalafil (Cialis)/Vardenafil (Levitra) 397
Talc 397
Tamoxifen (Nolvadex) 397
Thioridazine (Mellaril) 398
Topiramate 398
Lipid Storage Diseases 398
Farber's Disease (Glycolipid) (Autosomal Recessive [AR]) 399
Mucolipidosis (Mucopolysaccharidoses) (AR) 399
Niemann–Pick Disease (Ceramide Phosphatidyl Choline) (AR) 399
Sandhoff's Disease (Gangliosidosis Type II) (AR) 399
Tay–Sachs Disease (Gangliosidosis Type I) (AR) 399
Peripheral Retinal Degenerations 399
Lattice Degeneration 399
Pavingstone (Cobblestone) Degeneration 400
Peripheral Cystoid Degeneration 401
Snail Track Degeneration 401
Retinoschisis 401
Definition 401
Chapter 11: Optic Nerve and Glaucoma 499
Papilledema 499
Definition 499
Etiology 499
Symptoms 499
Signs 499
Differential Diagnosis 500
Evaluation 500
Prognosis 500
Idiopathic Intracranial Hypertension (Pseudotumor Cerebri) 501
Definition 501
Etiology 501
Epidemiology 501
Symptoms 501
Signs 501
Differential Diagnosis 501
Evaluation 502
Prognosis 502
Optic Neuritis 502
Definition 502
Papillitis 502
Retrobulbar 502
Devic's Syndrome 503
Etiology 503
Epidemiology 503
Symptoms 503
Signs 503
Differential Diagnosis 503
Evaluation 503
Prognosis 504
Anterior Ischemic Optic Neuropathy 504
Definition 504
Etiology 504
Arteritic 504
Nonarteritic 504
Epidemiology 505
Chapter 12: Visual Acuity, Refractive Procedures, and Sudden Vision Loss 539
Refractive Error 539
Definition 539
Ametropia 539
Anisometropia 539
Astigmatism 539
Emmetropia 540
Hyperopia (Farsightedness) 540
Myopia (Nearsightedness) 540
Presbyopia 540
Etiology 540
Astigmatism 540
Hyperopia 540
Myopia 541
Presbyopia 541
Epidemiology 541
Symptoms 541
Signs 541
Differential Diagnosis 541
Evaluation 541
Prognosis 542
Refractive Surgery Complications 542
Intraocular Refractive Procedures 542
Refractive Lens Exchange 542
Phakic Intraocular Lens 542
Symptoms 543
Signs and Complications 543
Corneal Refractive Procedures 543
Incisional 543
Radial keratotomy (RK) 543
Astigmatic keratotomy 544
Limbal relaxing incisions/peripheral corneal relaxing incisions 544
Symptoms 544
Signs and Complications 544
Excimer Laser 544
Photorefractive keratectomy (PRK) 544
Laser-assisted subepithelial keratectomy and epithelial-laser in-situ keratomileusis 545
Laser in-situ keratomileusis 545
Symptoms 545
Signs and Complications 545
Implants 548
Intracorneal inlays 548
Intrastromal corneal ring segments (Intacs) 548
Appendix 565
Ophthalmic History and Examination 565
History 565
Ocular Examination 565
Vision 565
Visual acuity 565
Refraction 568
Retinoscopy 569
Lensometer 569
Potential acuity meter (PAM) 570
Contrast sensitivity 570
Color vision 571
Stereopsis 571
4-Diopter base-out prism test 572
Worth 4-dot test 572
Ocular Motility 572
Cover tests 573
Cover–uncover test 573
Alternate cover test (prism and cover test) 574
Corneal light reflex tests 575
Hirschbergs method 575
Modified Krimsky's method 575
Forced ductions 576
Optokinetic nystagmus (OKN) testing 576
Pupils 577
Visual Fields 577
Amsler grid 578
Tangent screen 578
Goldmann visual field 578
Humphrey visual field 579
External Examination 579
Exophthalmometry 579
Schirmer's test 580
Jones' dye tests 580
Other cranial nerve examination 580
Slit-Lamp Examination (SLE) 581
Components of the slit-lamp examination 581
Lids, lashes, and lacrimal glands 581
Conjunctiva and sclera 581
Cornea 582
Anterior chamber 582
Iris and lens 582
Dyes 582
Gonioscopy 582
Fundus contact and noncontact lenses 583
Tonometry 583
Specialized Tests 584
Pachymetry 584
Keratometry 585
Corneal topography/tomography 586
Wavefront aberrometry 586
Specular microscopy 586
Confocal microscopy 587
Anterior segment–ocular coherence tomography (AS-OCT) 587
Fundus Examination 587
Components of the fundus examination 589
Disc 589
Vessels 589
Macula 589
Peripheral retina 589
Specialized Tests 589
Ultrasonography 589
A-scan (amplitude) 589
B-scan (brightness) 590
Partial coherence laser interferometry (IOLMaster) and optical low coherence reflectometry (Lenstar) 590
Optical coherence tomography 591
AAO Suggested Routine Eye Examination Guidelines 592
Differential Diagnosis of Common Ocular Symptoms 592
Decreased Vision 592
Visual Distortion 592
Glare/Halos 593
Photophobia 593
Diplopia 593
Night Blindness 593
Eye Pain 593
Red Eye 593
Tearing 595
Discharge 595
Lid Swelling 595
Lid Twitch 595
Flashes of Light 595
Floaters 595
Common Ophthalmic Medications 595
Anti-Infectives 595
Antibiotics 595
Aminoglycosides 595
Fluoroquinolones 595
Penicillins 596
Cephalosporins 596
Macrolides 596
Peptides 596
Sulfonamides 597
Tetracyclines 597
Miscellaneous antibiotics 597
Antibiotic/steroid combinations 597
Antiamoebics 597
Antifungals 598
Antivirals 598
Anti-inflammatory medications 598
NSAIDs 598
Immunomodulator 599
Steroids 599
Ocular Hypotensive (Glaucoma) Medications 599
Alpha-Adrenergic Receptor Agonists (Purple Cap) 599
Beta-Blockers (Yellow or Blue Cap) 599
Cholinergic Agonists (Miotics; Green Cap) 600
Carbonic Anhydrase Inhibitors (Orange Cap) 600
Prostaglandin Analogues (Turquoise/Teal Cap) 600
Hyperosmotics 601
Combinations 601
Allergy Medications 601
Mydriatics/Cycloplegics 601
Anesthetics 602
Miscellaneous 602
Color Codes for Topical Ocular Medication Caps 602
Ocular Toxicology 603
List of Important Ocular Measurements 604
List of Eponyms 604
Common Ophthalmic Abbreviations (How to Read an Ophthalmology Chart) 608
Common Spanish Phrases 610
Index 613