BOOK
SPEC - Andrews' Diseases of the Skin E-Book 12Month Subscription
William D. James | Dirk Elston | Timothy Berger
(2011)
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Book Details
Abstract
The 11th Edition of the classic Andrews’ Diseases of the Skin, by Drs. William D. James, Timothy G. Berger and Dirk M. Elston, provides the ultimate foundation in dermatology with comprehensive guidance to effectively diagnose and treat a wide range of skin conditions. These highly respected authors balance evidence-based treatment guidelines with advice from their own clinical experience, offering a practical and realistic medical perspective. Updated throughout with the latest dermatologic findings and a new chapter on cosmetic surgical techniques, this title helps you keep current, improve your skills, and prepare for exams. It is an indispensable, convenient reference for trainees and practicing dermatologists.
- Practice with confidence through the valued authorship of seasoned professionals Dr. William D. James, Dr. Timothy G. Berger, and Dr. Dirk M. Elston.
- Rapidly improve your knowledge of skin conditions through a concise, clinically focused, user-friendly format.
- Obtain thorough guidance on clinical presentation and therapy for a full range of common and rare skin diseases.
- Confirm your diagnoses by comparing your clinical findings to more than 1,150 illustrations, 40% of which are brand new.
- Update your surgical skills with chapters devoted to basic dermatologic, laser, and cosmetic surgery, contributed by Dr. Issac M. Neuhaus.
Table of Contents
| Section Title | Page | Action | Price |
|---|---|---|---|
| Front cover | cover | ||
| Andrew's Diseases of the Skin | i | ||
| Copyright page | iv | ||
| Table of contents | v | ||
| Preface and Acknowledgements | vi | ||
| Dedication | vii | ||
| Contributor | viii | ||
| Chapter 1: Skin: | 1 | ||
| Epidermis and adnexa | 1 | ||
| Langerhans cells | 3 | ||
| Dermoepidermal junction | 4 | ||
| Epidermal appendages: adnexa | 4 | ||
| Sebaceous glands | 7 | ||
| Nails | 8 | ||
| Dermis | 9 | ||
| Mast cells | 10 | ||
| Subcutaneous tissue (fat) | 10 | ||
| Chapter 2: Cutaneous Signs and Diagnosis | 12 | ||
| Cutaneous signs | 12 | ||
| General diagnosis | 15 | ||
| Hair, nails, and oral mucosa | 17 | ||
| Chapter 3: Dermatoses Resulting from Physical Factors | 18 | ||
| Heat injuries | 18 | ||
| Hot tar burns | 19 | ||
| Treatment | 20 | ||
| Erythema ab igne | 20 | ||
| Cold injuries | 21 | ||
| Acrocyanosis | 21 | ||
| Chapter 4: Pruritus and Neurocutaneous Dermatoses | 45 | ||
| Pruritus | 45 | ||
| Treatment | 45 | ||
| Internal causes of pruritus | 46 | ||
| Chronic kidney disease | 46 | ||
| Primary biliary cirrhosis | 47 | ||
| Polycythemia vera | 47 | ||
| Pruritic dermatoses | 48 | ||
| Winter itch | 48 | ||
| Treatment | 49 | ||
| Pruritus scroti | 49 | ||
| Treatment | 50 | ||
| Puncta pruritica (itchy points) | 50 | ||
| Aquagenic pruritus and aquadynia | 50 | ||
| Scalp pruritus | 50 | ||
| Drug-induced pruritus | 50 | ||
| Treatment | 51 | ||
| Prurigo pigmentosa | 51 | ||
| Papuloerythroderma of Ofuji | 51 | ||
| Treatment | 52 | ||
| Treatment | 53 | ||
| Psychodermatology | 53 | ||
| Skin signs of psychiatric illness | 53 | ||
| Delusions of parasitosis | 54 | ||
| Neurotic excoriations | 55 | ||
| Factitious dermatitis (dermatitis artefacta) | 55 | ||
| Trichotillomania | 56 | ||
| Body dysmorphic disorder (dysmorphic syndrome, dysmorphophobia) | 57 | ||
| Neurocutaneous dermatoses | 57 | ||
| Scalp dysesthesia | 57 | ||
| Burning mouth syndrome (glossodynia, burning tongue) | 57 | ||
| Vulvodynia | 57 | ||
| Notalgia paresthetica | 58 | ||
| Brachioradial pruritus | 58 | ||
| Meralgia paresthetica (Roth–Bernhardt disease) | 58 | ||
| Complex regional pain syndrome | 58 | ||
| Trigeminal trophic lesions | 59 | ||
| Mal perforans pedis | 60 | ||
| Sciatic nerve injury | 60 | ||
| Syringomyelia | 60 | ||
| Congenital insensitivity to pain with anhidrosis | 61 | ||
| Chapter 5: Atopic Dermatitis, Eczema, and Noninfectious Immunodeficiency Disorders | 62 | ||
| Atopic dermatitis | 62 | ||
| Management of an acute flare | 69 | ||
| Eczema | 70 | ||
| Hormone-induced dermatoses | 77 | ||
| Immunodeficiency syndromes | 78 | ||
| Disorders of antibody deficiency | 79 | ||
| X-linked agammaglobulinemia (XLA) | 79 | ||
| Isolated IgA deficiency | 79 | ||
| Common variable immunodeficiency | 79 | ||
| Class-switch recombination defects (formerly immunodeficiency with hyper-IgM) | 80 | ||
| Thymoma with immunodeficiency | 80 | ||
| DiGeorge syndrome | 80 | ||
| Purine nucleoside phosphorylase deficiency | 80 | ||
| Severe combined immunodeficiency disease | 81 | ||
| WHIM syndrome | 82 | ||
| Wiskott–Aldrich syndrome | 82 | ||
| Ataxia telangiectasia | 82 | ||
| Defects of phagocyte number, function, or both | 83 | ||
| Chronic granulomatous disease | 83 | ||
| Leukocyte adhesion molecule deficiency | 84 | ||
| Hyperimmunoglobulinemia E syndrome | 84 | ||
| Complement deficiency | 85 | ||
| GVHD in solid organ transplantation | 87 | ||
| Chapter 6: Contact Dermatitis and Drug Eruptions | 88 | ||
| Contact dermatitis | 88 | ||
| Solvents | 90 | ||
| Lower extremities | 93 | ||
| Testing for plant allergens | 97 | ||
| Dermatitis from clothing | 97 | ||
| Shoe dermatitis | 98 | ||
| Other metals | 101 | ||
| Contact stomatitis | 101 | ||
| Antioxidants | 101 | ||
| Adhesive dermatitis | 101 | ||
| Acrylic monomers | 102 | ||
| Cosmetic intolerance syndrome | 104 | ||
| p-Chloro-meta-xylenol (PCMX) | 105 | ||
| Ethylenediamine | 105 | ||
| Corticosteroids | 106 | ||
| Management | 106 | ||
| Management | 108 | ||
| Drug reactions | 108 | ||
| Exanthems (morbilliform or maculopapular reactions) | 110 | ||
| Dapsone hypersensitivity syndrome | 113 | ||
| Bullous drug reactions (Stevens–Johnson syndrome [SJS] and toxic epidermal necrolysis [TEN]) | 114 | ||
| Radiation-induced erythema multiforme | 116 | ||
| HIV disease and drug reactions | 116 | ||
| Fixed drug reactions | 117 | ||
| Acute generalized exanthematous pustulosis | 119 | ||
| Drug-induced pseudolymphoma | 120 | ||
| Red man syndrome | 121 | ||
| Photosensitivity reactions (photosensitive drug reactions) | 122 | ||
| Anticoagulant-induced skin necrosis | 124 | ||
| Injection site reactions | 125 | ||
| Drug-induced pigmentation | 126 | ||
| Vasculitis and serum sickness-like reactions | 128 | ||
| Lichenoid reactions | 128 | ||
| Adverse reactions to immunosuppressants used in dermatology | 131 | ||
| Adverse reactions to biologic agents | 132 | ||
| TNF inhibitors | 132 | ||
| Iododerma | 134 | ||
| Leukotriene receptor antagonist-associated Churg–Strauss syndrome | 135 | ||
| Systemic complications | 137 | ||
| Chapter 7: Erythema and Urticaria | 138 | ||
| Flushing | 138 | ||
| Erythemas | 138 | ||
| Treatment | 141 | ||
| Oral erythema multiforme | 141 | ||
| Annular erythema of infancy | 142 | ||
| Eosinophilic cellulitis (Wells syndrome) | 142 | ||
| Reactive neutrophilic dermatoses | 143 | ||
| Marshall syndrome | 145 | ||
| Pyoderma gangrenosum | 145 | ||
| Autoinflammatory syndromes | 147 | ||
| Urticaria (hives) | 147 | ||
| Galvanic urticaria | 154 | ||
| Chapter 8: Connective Tissue Diseases | 155 | ||
| Lupus erythematosus | 155 | ||
| Other therapy | 164 | ||
| Dermatomyositis | 165 | ||
| Prognosis | 168 | ||
| Scleroderma | 169 | ||
| Treatment | 173 | ||
| Eosinophilic fasciitis | 175 | ||
| Mixed connective tissue disease | 176 | ||
| Nephrogenic systemic fibrosis | 176 | ||
| Sjögren syndrome (sicca syndrome) | 177 | ||
| Rheumatoid arthritis | 178 | ||
| Related palisading granulomas | 179 | ||
| Juvenile rheumatoid arthritis (juvenile idiopathic arthritis) | 180 | ||
| Relapsing polychondritis | 180 | ||
| Chapter 9: Mucinoses | 182 | ||
| Lichen myxedematosus | 182 | ||
| Atypical or intermediate lichen myxedematosus | 184 | ||
| Scleredema | 185 | ||
| Reticular erythematous mucinosis (REM syndrome, plaque-like cutaneous mucinosis) | 185 | ||
| Follicular mucinosis (alopecia mucinosa) | 186 | ||
| Cutaneous focal mucinosis | 187 | ||
| Myxoid cysts | 187 | ||
| Chapter 10: Seborrheic Dermatitis, Psoriasis, Recalcitrant Palmoplantar Eruptions, Pustular Dermatitis, and Erythroderma | 188 | ||
| Seborrheic dermatitis | 188 | ||
| Treatment | 189 | ||
| Psoriasis | 190 | ||
| Alternative therapies | 198 | ||
| Reactive arthritis with conjunctivitis/urethritis/diarrhea (Reiter syndrome) | 199 | ||
| Clinical features | 199 | ||
| Subcorneal pustular dermatosis (Sneddon–Wilkinson disease) | 200 | ||
| Eosinophilic pustular folliculitis | 200 | ||
| Recalcitrant palmoplantar eruptions | 201 | ||
| Palmoplantar pustulosis (pustular psoriasis of the extremities) | 201 | ||
| Pustular bacterid | 202 | ||
| Infantile acropustulosis | 202 | ||
| Chapter 11: Pityriasis Rosea, Pityriasis Rubra Pilaris, and Other Papulosquamous and Hyperkeratotic Diseases | 203 | ||
| Small plaque parapsoriasis | 203 | ||
| Confluent and reticulated papillomatosis (Gougerot and Carteaud) | 203 | ||
| Pityriasis rosea | 204 | ||
| Treatment | 205 | ||
| Pityriasis rubra pilaris | 205 | ||
| Treatment | 207 | ||
| Palmoplantar keratoderma | 207 | ||
| Aquagenic wrinkling of the palms (acquired aquagenic syringeal acrokeratoderma) | 210 | ||
| Exfoliative dermatitis (erythroderma) | 211 | ||
| Treatment | 212 | ||
| Chapter 12: Lichen Planus and Related Conditions | 213 | ||
| Lichen planus | 213 | ||
| Treatment | 218 | ||
| Follicular lichen planus (lichen planopilaris) | 220 | ||
| Idiopathic eruptive macular pigmentation | 221 | ||
| Keratosis lichenoides chronica | 221 | ||
| Lichen nitidus | 222 | ||
| Clinical features | 222 | ||
| Lichen striatus | 223 | ||
| Lichen sclerosus (lichen sclerosus et atrophicus) | 224 | ||
| Treatment | 225 | ||
| Chapter 13: Acne | 228 | ||
| Acne vulgaris | 228 | ||
| Complications | 234 | ||
| Acne conglobata | 235 | ||
| Acne fulminans | 236 | ||
| SAPHO syndrome | 236 | ||
| Other acne variants | 236 | ||
| Excoriated acne | 237 | ||
| Acneiform eruptions | 237 | ||
| Gram-negative folliculitis | 238 | ||
| Acne keloidalis | 238 | ||
| Hidradenitis suppurativa | 239 | ||
| Treatment | 240 | ||
| Dissecting cellulitis of the scalp | 240 | ||
| Acne miliaris necrotica (acne varioliformis) | 241 | ||
| Rosacea | 241 | ||
| Surgical intervention | 244 | ||
| Pyoderma faciale | 244 | ||
| Perioral dermatitis | 245 | ||
| Periorbital dermatitis | 245 | ||
| Granulomatous facial dermatitis | 245 | ||
| Granulomatous perioral dermatitis in children | 245 | ||
| Chapter 14: Bacterial Infections | 247 | ||
| Infections caused by Gram-positive organisms | 247 | ||
| Gram-positive toxic shock syndromes | 253 | ||
| Streptococcal skin infections | 254 | ||
| Streptococcus iniae infections | 258 | ||
| Miscellaneous Gram-positive skin infections | 258 | ||
| Treatment | 259 | ||
| Pneumococcal cellulitis | 259 | ||
| Anthrax | 259 | ||
| Listeriosis | 260 | ||
| Cutaneous diphtheria | 260 | ||
| Corynebacterium jeikeium sepsis | 261 | ||
| Desert sore | 261 | ||
| Tropical ulcer | 261 | ||
| Erythrasma | 261 | ||
| Arcanobacterium haemolyticum infection | 262 | ||
| Intertrigo | 262 | ||
| Pitted keratolysis | 262 | ||
| Clostridial infections and gangrene of the skin (dermatitis gangrenosa) | 263 | ||
| Fournier gangrene of the penis or scrotum | 264 | ||
| Actinomycosis | 264 | ||
| Nocardiosis | 264 | ||
| Infections caused by Gram-negative organisms | 265 | ||
| Gram-negative folliculitis | 267 | ||
| Malacoplakia (malakoplakia) | 267 | ||
| Haemophilus influenzae cellulitis | 267 | ||
| Chancroid | 268 | ||
| Treatment | 269 | ||
| Granuloma inguinale (granuloma venereum, donovanosis) | 269 | ||
| Treatment | 270 | ||
| Gonococcal dermatitis | 270 | ||
| Gonococcemia | 270 | ||
| Meningococcemia | 270 | ||
| Vibrio vulnificus infection | 271 | ||
| Chromobacteriosis and Aeromonas infections | 271 | ||
| Salmonellosis | 272 | ||
| Shigellosis | 272 | ||
| Helicobacter cellulitis | 272 | ||
| Rhinoscleroma | 272 | ||
| Treatment | 273 | ||
| Pasteurellosis | 273 | ||
| Dog and human bite pathogens | 273 | ||
| Glanders | 274 | ||
| Melioidosis | 274 | ||
| Infections caused by Bartonella | 274 | ||
| Oroya fever and verruga peruana | 276 | ||
| Plague | 277 | ||
| Rat-bite fever | 277 | ||
| Tularemia | 278 | ||
| Brucellosis | 279 | ||
| Rickettsial diseases | 279 | ||
| Rickettsialpox | 280 | ||
| Ehrlichiosis | 281 | ||
| Leptospirosis | 282 | ||
| Borreliosis | 282 | ||
| Acrodermatitis chronica atrophicans | 284 | ||
| Mycoplasma | 284 | ||
| Chlamydial infections | 285 | ||
| Lymphogranuloma venereum | 285 | ||
| Treatment | 286 | ||
| Chapter 15: Diseases Resulting from Fungi and Yeasts | 287 | ||
| Superficial and deep mycoses | 287 | ||
| Antifungal therapy | 287 | ||
| The Superficial Mycoses | 288 | ||
| Treatment | 296 | ||
| Candidiasis | 297 | ||
| Antibiotic (iatrogenic) candidiasis | 301 | ||
| Geotrichosis | 301 | ||
| Tinea nigra | 302 | ||
| Piedra (trichosporosis) | 302 | ||
| Tinea versicolor (pityriasis versicolor) | 302 | ||
| Pityrosporum folliculitis | 303 | ||
| The deep mycoses | 304 | ||
| Treatment | 305 | ||
| Histoplasmosis | 306 | ||
| Treatment | 307 | ||
| Cryptococcosis | 307 | ||
| Treatment | 308 | ||
| North American blastomycosis | 309 | ||
| Treatment | 310 | ||
| South American blastomycosis | 310 | ||
| Treatment | 311 | ||
| Sporotrichosis | 311 | ||
| Treatment | 312 | ||
| Chromoblastomycosis | 313 | ||
| Treatment | 314 | ||
| Phaeohyphomycosis | 314 | ||
| Alternariosis | 315 | ||
| Mycetoma | 315 | ||
| Treatment | 316 | ||
| Keloidal blastomycosis (lobomycosis) | 316 | ||
| Rhinosporidiosis | 317 | ||
| Zygomycosis (phycomycosis) | 317 | ||
| Treatment | 318 | ||
| Hyalohyphomycosis | 319 | ||
| Fusariosis | 319 | ||
| Aspergillosis | 319 | ||
| Treatment | 320 | ||
| Disease caused by algae (protothecosis) | 320 | ||
| Chapter 16: Mycobacterial Diseases | 322 | ||
| Tuberculosis | 322 | ||
| Treatment | 328 | ||
| Atypical mycobacteriosis | 329 | ||
| Mycobacterium kansasii | 332 | ||
| Chapter 17: Hansen’s Disease | 334 | ||
| Epidemiology | 334 | ||
| The infectious agent | 334 | ||
| Diagnosis | 335 | ||
| Classification | 335 | ||
| Nerve involvement | 337 | ||
| Ocular involvement | 339 | ||
| Mucous membrane involvement | 339 | ||
| Visceral involvement | 339 | ||
| Pregnancy and Hansen’s disease | 339 | ||
| Human immunodeficiency virus (HIV) and Hansen’s disease | 339 | ||
| Pathogenesis | 339 | ||
| Histopathology | 340 | ||
| Reactional states | 340 | ||
| Treatment | 341 | ||
| Management of reactions | 343 | ||
| Prevention | 343 | ||
| Chapter 18: Syphilis, Yaws, Bejel, and Pinta | 345 | ||
| Syphilis | 345 | ||
| Syphilis and HIV disease | 356 | ||
| Nonvenereal treponematoses: yaws, endemic syphilis, and pinta | 357 | ||
| Treatment | 359 | ||
| Chapter 19: Viral Diseases | 360 | ||
| Herpesvirus group | 360 | ||
| Differential diagnosis | 367 | ||
| Immunocompromised patients | 371 | ||
| Inflammatory skin lesions following a zoster infection (isotopic response) | 376 | ||
| Cytomegalic inclusion disease | 378 | ||
| Human herpesvirus-8 | 379 | ||
| B virus | 380 | ||
| Infectious hepatitis | 380 | ||
| Hepatitis C virus | 380 | ||
| Gianotti–Crosti syndrome (papular acrodermatitis of childhood, papulovesicular acrolocated syndrome) | 382 | ||
| Poxvirus group | 383 | ||
| Variola major (smallpox) | 383 | ||
| Other skin lesions at vaccination scars | 385 | ||
| Parapoxvirus infections from wildlife | 387 | ||
| Molluscum contagiosum | 387 | ||
| Picornavirus group | 389 | ||
| Eruptive pseudoangiomatosis | 391 | ||
| Paramyxovirus group | 391 | ||
| Congenital rubella syndrome | 392 | ||
| Asymmetric periflexural exanthem of childhood (APEC) | 393 | ||
| Parvovirus group | 393 | ||
| Other skin findings attributed to parvovirus B19 | 394 | ||
| Arbovirus group (togaviridae) | 395 | ||
| Alphavirus | 396 | ||
| Papovavirus group | 397 | ||
| Immunosuppressed patients | 406 | ||
| Viral-associated trichodysplasia (cyclosporine-induced folliculodystrophy) | 408 | ||
| Retroviruses | 408 | ||
| Human T-lymphotropic virus-1 | 408 | ||
| AIDS and Kaposi sarcoma | 412 | ||
| Chapter 20: Parasitic Infestations, Stings, and Bites | 414 | ||
| Phylum protozoa | 414 | ||
| Other ameba | 414 | ||
| Trichomoniasis | 415 | ||
| Viscerotropic leishmaniasis | 419 | ||
| Human trypanosomiasis | 420 | ||
| Class Sporozoa | 421 | ||
| Toxoplasmosis | 421 | ||
| Phylum Cnidaria | 421 | ||
| Dogger Bank itch | 423 | ||
| Phylum Platyhelminthes | 423 | ||
| Visceral schistosomiasis (bilharziasis) | 424 | ||
| Cysticercosis cutis | 425 | ||
| Sparganosis | 425 | ||
| Echinococcosis | 425 | ||
| Phylum Annelida | 425 | ||
| Leeches | 425 | ||
| Phylum Nemathelminthes | 426 | ||
| Class Nematoda | 426 | ||
| Enterobiasis (pinworm infection, seatworm infection, oxyuriasis) | 426 | ||
| Larva currens | 427 | ||
| Dracunculiasis (Guinea worm disease, dracontiasis, medina worm) | 428 | ||
| Filariasis | 428 | ||
| Elephantiasis tropica (elephantiasis arabum) | 428 | ||
| Loiasis (loa loa, Calabar swelling, tropical swelling, fugitive swelling) | 429 | ||
| Onchocerciasis | 430 | ||
| Trichinosis | 431 | ||
| Pneumocystosis | 431 | ||
| Phylum Arthropoda | 432 | ||
| Prevention of flea-borne illness | 433 | ||
| Centipede bites (Chilopoda) | 433 | ||
| Millipede burns (Diplopoda) | 434 | ||
| Moth dermatitis | 435 | ||
| Cimicosis (bedbug bites) | 435 | ||
| Reduviid bites | 435 | ||
| Pediculosis pubis (crabs) | 437 | ||
| Mosquito bites | 438 | ||
| Myiasis | 438 | ||
| Other beetles | 439 | ||
| Ants | 440 | ||
| Tungiasis | 441 | ||
| Tick paralysis | 442 | ||
| Other mite-related dermatitis | 445 | ||
| Order Scorpionidae | 445 | ||
| Scorpion sting | 445 | ||
| Tarantulas (Lycosidae: Theraphosidae) | 446 | ||
| Phylum Chordata | 447 | ||
| Lizard bite | 447 | ||
| Chapter 21: Chronic Blistering Dermatoses | 448 | ||
| Pemphigus vulgaris | 448 | ||
| Pemphigus vegetans | 451 | ||
| Pemphigus foliaceus | 452 | ||
| Endemic pemphigus (fogo selvagem) | 453 | ||
| Pemphigus erythematosus (Senear–Usher syndrome) | 453 | ||
| Paraneoplastic pemphigus | 453 | ||
| Intraepidermal neutrophilic IgA dermatosis | 454 | ||
| Bullous pemphigoid | 455 | ||
| Course and prognosis | 457 | ||
| Pemphigoid gestationis (herpes gestationis) | 457 | ||
| Other pregnancy-related dermatoses | 458 | ||
| Impetigo herpetiformis | 459 | ||
| Cicatricial pemphigoid (benign mucosal pemphigoid) | 460 | ||
| Treatment | 461 | ||
| Epidermolysis bullosa acquisita | 461 | ||
| Treatment | 462 | ||
| Dermatitis herpetiformis (Duhring disease) | 463 | ||
| Gluten-free diet | 464 | ||
| Linear IgA bullous dermatosis | 465 | ||
| Childhood linear IgA disease (chronic bullous disease of childhood) | 465 | ||
| Transient acantholytic dermatosis (Grover’s disease) | 466 | ||
| Chapter 22: Nutritional Diseases | 468 | ||
| Vitamin A | 468 | ||
| Hypervitaminosis A | 469 | ||
| Vitamin D | 469 | ||
| Vitamin K deficiency | 469 | ||
| Vitamin B1 deficiency | 470 | ||
| Vitamin B2 deficiency | 470 | ||
| Vitamin B6 | 470 | ||
| Pyridoxine excess | 470 | ||
| Vitamin B12 deficiency | 470 | ||
| Folic acid deficiency | 470 | ||
| Scurvy | 471 | ||
| Niacin deficiency (pellagra) | 472 | ||
| Diagnosis and treatment | 472 | ||
| Biotin deficiency | 473 | ||
| Zinc deficiency | 473 | ||
| Essential fatty acid deficiency | 474 | ||
| Iron deficiency | 475 | ||
| Selenium deficiency | 475 | ||
| Protein–energy malnutrition | 475 | ||
| Kwashiorkor | 475 | ||
| Carotenemia and lycopenemia | 476 | ||
| Chapter 23: Diseases of Subcutaneous Fat | 477 | ||
| Septal panniculitis (acute and chronic erythema nodosum) | 477 | ||
| Lobular panniculitis | 479 | ||
| Nodular vasculitis | 479 | ||
| Sclerosing panniculitis (hypodermitis sclerodermiformis, lipodermatosclerosis, stasis panniculitis) | 479 | ||
| Physical panniculitis | 480 | ||
| Cold panniculitis | 481 | ||
| Post-steroid panniculitis | 482 | ||
| Traumatic panniculitis | 482 | ||
| Factitial panniculitis | 482 | ||
| Sclerosing lipogranuloma | 482 | ||
| Enzyme-related panniculitis | 483 | ||
| Pancreatic panniculitis (subcutaneous fat necrosis) | 483 | ||
| Alpha1-antitrypsin deficiency panniculitis | 483 | ||
| Cytophagic histiocytic panniculitis | 484 | ||
| Miscellaneous forms of panniculitis | 484 | ||
| Gouty panniculitis | 484 | ||
| Lipodystrophy (lipoatrophy) | 484 | ||
| Localized lipodystrophy | 486 | ||
| Chapter 24: Endocrine Diseases | 488 | ||
| Acromegaly | 488 | ||
| Cushing syndrome | 488 | ||
| Addison’s disease | 489 | ||
| Panhypopituitarism and growth hormone deficiency | 490 | ||
| Androgen-dependent syndromes | 490 | ||
| Hypothyroidism | 491 | ||
| Diagnosis and treatment | 492 | ||
| Hyperthyroidism | 492 | ||
| Hypoparathyroidism | 493 | ||
| Hyperparathyroidism | 493 | ||
| Acanthosis nigricans | 494 | ||
| Type III: acanthosis nigricans associated with insulin-resistant states and syndromes | 495 | ||
| Chapter 25: Abnormalities of Dermal Fibrous and Elastic Tissue | 497 | ||
| Collagen | 497 | ||
| Elastosis perforans serpiginosa | 497 | ||
| Reactive perforating collagenosis | 497 | ||
| Pseudoxanthoma elasticum | 498 | ||
| Perforating calcific elastosis | 499 | ||
| Ehlers–Danlos syndromes | 500 | ||
| Treatment | 501 | ||
| Marfan syndrome | 501 | ||
| Homocystinuria | 502 | ||
| Cutis laxa (generalized elastolysis) | 503 | ||
| Blepharochalasis | 503 | ||
| Anetoderma (macular atrophy) | 503 | ||
| Striae distensae | 504 | ||
| Linear focal elastosis (elastotic striae) | 504 | ||
| Acrodermatitis chronica atrophicans | 504 | ||
| Osteogenesis imperfecta | 505 | ||
| Chapter 26: Errors in Metabolism | 506 | ||
| Amyloidosis | 506 | ||
| Systemic amyloidoses | 506 | ||
| Cutaneous amyloidosis | 508 | ||
| Familial syndromes associated with amyloidosis (heredofamilial amyloidosis) | 510 | ||
| Porphyrias | 511 | ||
| Transient erythroporphyria of infancy (purpuric phototherapy-induced eruption) | 516 | ||
| Calcinosis cutis | 516 | ||
| Osteoma cutis | 518 | ||
| Lipid disturbances | 520 | ||
| Familial α-lipoprotein deficiency (hypoalphalipoproteinemia, Tangier disease) | 525 | ||
| Niemann–Pick disease | 526 | ||
| Gaucher’s disease | 526 | ||
| Lipoid proteinosis | 527 | ||
| Angiokeratoma corporis diffusum (Fabry disease) | 527 | ||
| Fucosidosis | 528 | ||
| Sialidosis | 528 | ||
| Beta-mannosidase deficiency | 529 | ||
| Skin disorders in diabetes mellitus | 529 | ||
| Necrobiosis lipoidica/necrobiosis lipoidica diabeticorum | 529 | ||
| Other diabetic dermadromes | 530 | ||
| Other associated conditions in patients with diabetes | 531 | ||
| Other metabolic disorders | 531 | ||
| Citrullinemia | 531 | ||
| Hartnup disease | 531 | ||
| Prolidase deficiency | 532 | ||
| Phenylketonuria | 532 | ||
| Alkaptonuria and ochronosis | 533 | ||
| Exogenous ochronosis | 533 | ||
| Wilson’s disease (hepatolenticular degeneration) | 534 | ||
| Tyrosinemia II (Richner–Hanhart syndrome) | 534 | ||
| Hurler syndrome (mucopolysaccharidosis I) | 534 | ||
| Hunter syndrome (mucopolysaccharidosis II) | 534 | ||
| Morquio’s disease (mucopolysaccharidosis IV) | 535 | ||
| Hyaluronidase deficiency (mucopolysaccharidosis IX) | 535 | ||
| Lafora’s disease | 535 | ||
| CADASIL syndrome | 535 | ||
| Farber disease | 536 | ||
| Adrenoleukodystrophy (Schilder’s disease) | 536 | ||
| Gout | 536 | ||
| Lesch–Nyhan syndrome | 536 | ||
| Chapter 27: Genodermatoses and Congenital Anomalies | 538 | ||
| X-linked, mosaic, and related disorders | 538 | ||
| Naegeli–Franceschetti–Jadassohn syndrome | 539 | ||
| Incontinentia pigmenti achromians (hypomelanosis of Ito) | 539 | ||
| Linear and whorled nevoid hypermelanosis | 540 | ||
| Chondrodysplasia punctata | 540 | ||
| Klinefelter syndrome | 541 | ||
| XXYY genotype | 541 | ||
| Turner syndrome | 541 | ||
| Noonan syndrome | 541 | ||
| Multiple lentigines (LEOPARD) syndrome | 541 | ||
| Cardio-facio-cutaneous syndrome | 542 | ||
| Phakomatoses | 542 | ||
| Treatment | 543 | ||
| Neurofibromatosis (von Recklinghausen’s disease) | 544 | ||
| Screening and monitoring for complications | 545 | ||
| Proteus syndrome | 545 | ||
| Other Epidermal Nevus Syndromes | 546 | ||
| Von Hippel–Lindau syndrome | 546 | ||
| Ataxia-telangiectasia | 546 | ||
| Epidermolysis bullosa | 547 | ||
| Recessive dystrophic epidermolysis bullosa (Hallopeau–Siemens) | 550 | ||
| Familial benign chronic pemphigus (Hailey–Hailey disease) | 550 | ||
| Disorders of cornification (ichthyoses and ichthyosiform syndromes) | 551 | ||
| Ichthyosis bullosa of Siemens | 554 | ||
| Restrictive dermopathy | 554 | ||
| Ichthyosis linearis circumflexa | 554 | ||
| Neutral lipid storage disease | 555 | ||
| Ichthyosis follicularis | 555 | ||
| Sjögren–Larsson syndrome | 555 | ||
| Refsum syndrome | 555 | ||
| Rud syndrome | 556 | ||
| Keratitis-ichthyosis-deafness syndrome | 556 | ||
| Congenital hemidysplasia with ichthyosiform erythroderma and limb defects syndrome | 556 | ||
| Erythrokeratodermia variabilis | 557 | ||
| Progressive symmetric erythrokeratodermia | 557 | ||
| Acquired ichthyosis | 557 | ||
| Pityriasis rotunda | 557 | ||
| Porokeratosis | 558 | ||
| Porokeratotic eccrine ostial and dermal duct nevus | 559 | ||
| Darier’s disease (keratosis follicularis, Darier–White disease) | 560 | ||
| Treatment | 560 | ||
| Acrokeratosis verruciformis | 560 | ||
| Pachyonychia congenita | 561 | ||
| Dyskeratosis congenita (Zinsser–Cole–Engman syndrome) | 561 | ||
| Fanconi syndrome | 562 | ||
| Ectodermal dysplasia | 562 | ||
| Lelis syndrome | 564 | ||
| Pachydermoperiostosis (idiopathic hypertrophic osteoarthropathy, Touraine–Solente–Gole syndrome) | 564 | ||
| Cutis verticis gyrata | 565 | ||
| Aplasia cutis congenita | 565 | ||
| Adams–Oliver syndrome | 565 | ||
| Focal dermal hypoplasia (Goltz syndrome) | 565 | ||
| Werner syndrome (adult progeria) | 566 | ||
| Progeria (Hutchinson–Gilford syndrome) | 566 | ||
| Xeroderma pigmentosum | 567 | ||
| Cockayne syndrome | 567 | ||
| Xeroderma pigmentosum/Cockayne syndrome complex | 568 | ||
| Trichothiodystrophy | 568 | ||
| Bloom syndrome (Bloom–Torre–Machacek syndrome) | 568 | ||
| Rothmund–Thomson syndrome (poikiloderma congenitale) | 569 | ||
| Hereditary sclerosing poikiloderma and mandibuloacral dysplasia | 569 | ||
| Scleroatrophic syndrome of Huriez | 569 | ||
| Franceschetti–Klein syndrome (mandibulofacial dysostosis) | 570 | ||
| Treacher Collins syndrome | 570 | ||
| Oculoauriculofrontonasal syndrome | 570 | ||
| Popliteal pterygium syndrome | 570 | ||
| Van der Woude syndrome | 570 | ||
| Apert syndrome (acrocephalosyndactyly) | 570 | ||
| Pfeiffer syndrome | 570 | ||
| Crouzon syndrome | 570 | ||
| Carpenter syndrome | 570 | ||
| Whistling face syndrome | 570 | ||
| Syndromes that include abnormalities of the hair | 570 | ||
| Atrichia with papules | 571 | ||
| Keratosis pilaris | 572 | ||
| Erythromelanosis follicularis faciei et colli | 572 | ||
| Follicular atrophoderma | 572 | ||
| Keratosis pilaris atrophicans | 572 | ||
| Keratosis follicularis spinulosa decalvans (Siemens-1 syndrome) | 573 | ||
| H syndrome | 573 | ||
| Chapter 28: Dermal and Subcutaneous Tumors | 574 | ||
| Cutaneous vascular anomalies | 574 | ||
| Phakomatosis pigmentovascularis | 574 | ||
| Eccrine angiomatous hamartoma | 574 | ||
| Malformations | 575 | ||
| Nevus oligemicus | 575 | ||
| Cutis marmorata telangiectatica congenita (congenital phlebectasia, van Lohuizen syndrome) | 575 | ||
| Nevus flammeus (port wine stain) | 575 | ||
| Deep venous malformations including cavernous venous malformation | 576 | ||
| Klippel–Trenaunay syndrome (hemangiectatic hypertrophy, angio-osteohypertrophy syndrome) | 578 | ||
| Arteriovenous fistulas | 578 | ||
| Acral arteriolar ectasia | 579 | ||
| Superficial lymphatic malformation (lymphangioma circumscriptum) | 579 | ||
| Cystic lymphatic malformation | 579 | ||
| Gorham–Stout syndrome | 580 | ||
| Solitary angiokeratoma | 582 | ||
| Lymphangiectasis (lymphangioma) | 582 | ||
| Hyperplasias | 583 | ||
| Angiolymphoid hyperplasia with eosinophilia | 583 | ||
| Pyogenic granuloma | 583 | ||
| Intravascular papillary endothelial hyperplasia | 584 | ||
| Angioma serpiginosum | 584 | ||
| Benign neoplasms | 584 | ||
| Infantile hemangioma (strawberry hemangioma) | 584 | ||
| Cherry angiomas (senile angiomas, de Morgan spots) | 586 | ||
| Targetoid hemosiderotic hemangioma | 586 | ||
| Glomeruloid hemangioma | 586 | ||
| Microvenular hemangioma | 586 | ||
| Tufted angioma (angioblastoma) | 587 | ||
| Kaposiform hemangioendothelioma | 587 | ||
| Multifocal lymphangioendotheliomatosis | 587 | ||
| Kasabach–Merritt syndrome (hemangioma with thrombocytopenia) | 587 | ||
| Acquired progressive lymphangioma (benign lymphangioendothelioma) | 588 | ||
| Glomus tumor (glomangioma) | 588 | ||
| Lesions formerly classified as hemangiopericytomas | 589 | ||
| Proliferating angioendotheliomatosis | 589 | ||
| Hemangioendotheliomas | 589 | ||
| Course | 591 | ||
| Composite hemangioendothelioma | 592 | ||
| Endovascular papillary angioendothelioma (Dabska tumor) | 592 | ||
| Angiosarcoma | 592 | ||
| Fibrous tissue abnormalities | 593 | ||
| Keloid | 593 | ||
| Plantar fibromatosis | 594 | ||
| Peyronie’s disease | 594 | ||
| Knuckle pads | 595 | ||
| Pachydermodactyly | 595 | ||
| Desmoid tumor | 595 | ||
| Collagenous fibroma (desmoplastic fibroblastoma) | 595 | ||
| Aponeurotic fibroma | 596 | ||
| Aggressive infantile fibromatosis | 596 | ||
| Juvenile hyaline fibromatosis and infantile systemic hyalinosis | 596 | ||
| Infantile digital fibromatosis (infantile digital myofibroblastoma, inclusion body fibroma) | 597 | ||
| Fibrous hamartoma of infancy | 597 | ||
| Fibromatosis colli | 597 | ||
| Giant cell tumor of the tendon sheath | 597 | ||
| Pseudo-ainhum | 598 | ||
| Connective tissue nevi | 598 | ||
| Elastofibroma dorsi | 599 | ||
| Angiofibromas | 599 | ||
| Fibrous papule of the nose (fibrous papule of the face, benign solitary fibrous papule) | 599 | ||
| Acral fibrokeratoma | 599 | ||
| Superficial acral fibromyxoma | 600 | ||
| Subungual exostosis | 600 | ||
| Chondrodermatitis nodularis chronica helicis | 600 | ||
| Oral submucous fibrosis | 600 | ||
| Fascial hernia | 600 | ||
| Cutaneous pseudosarcomatous polyp and umbilical polyp | 601 | ||
| Epithelioid cell histiocytoma | 602 | ||
| Dermal dendrocyte hamartoma | 602 | ||
| Nodular fasciitis (nodular pseudosarcomatous fasciitis) | 602 | ||
| Solitary fibrous tumor | 603 | ||
| Plexiform fibrohistiocytic tumor | 603 | ||
| Dermatofibrosarcoma protuberans | 603 | ||
| Atypical fibroxanthoma | 603 | ||
| Cutaneous myxofibrosarcoma | 604 | ||
| Epithelioid sarcoma | 604 | ||
| Myxomas | 605 | ||
| Aggressive angiomyxoma | 605 | ||
| Mastocytosis | 605 | ||
| Treatment | 608 | ||
| Abnormalities of neural tissue | 609 | ||
| Granular cell tumor | 609 | ||
| Perineurioma | 609 | ||
| Neuroma cutis | 610 | ||
| Neurothekeoma (nerve sheath myxoma) | 610 | ||
| Schwannoma (neurilemmoma) | 610 | ||
| Infantile neuroblastoma | 611 | ||
| Ganglioneuroma | 611 | ||
| Nasal glioma (cephalic brainlike heterotopias) | 611 | ||
| Cutaneous meningioma | 611 | ||
| Chordomas | 612 | ||
| Abnormalities of fat tissue | 612 | ||
| Subtypes | 613 | ||
| Nevus lipomatosus superficialis | 614 | ||
| Folded skin with scarring (Michelin tire baby syndrome) | 614 | ||
| Benign lipoblastoma | 614 | ||
| Liposarcoma | 614 | ||
| Abnormalities of smooth muscle | 614 | ||
| Treatment | 615 | ||
| Congenital smooth muscle hamartoma | 615 | ||
| Leiomyosarcoma | 616 | ||
| Miscellaneous tumors and tumor-associated conditions | 616 | ||
| Cutaneous endometriosis | 616 | ||
| Teratoma | 616 | ||
| Metastatic carcinoma | 616 | ||
| Paraneoplastic syndromes | 617 | ||
| Treatment | 619 | ||
| Chapter 29: Epidermal Nevi, Neoplasms, and Cysts | 620 | ||
| Epidermal nevi | 620 | ||
| Keratinocytic epidermal nevi | 620 | ||
| Nevus comedonicus | 621 | ||
| Epidermal nevus syndrome | 621 | ||
| Inflammatory linear verrucous epidermal nevus | 622 | ||
| Hyperkeratosis of the nipple and areola | 623 | ||
| Clear cell acanthoma (pale cell acanthoma) | 624 | ||
| Waxy keratoses of childhood (kerinokeratosis papulosa) | 624 | ||
| Multiple minute digitate hyperkeratosis | 624 | ||
| Acantholytic acanthoma, epidermolytic acanthoma, acantholytic dyskeratotic acanthoma | 624 | ||
| Warty dyskeratoma | 625 | ||
| Seborrheic keratosis | 625 | ||
| Sign of Leser–Trélat | 625 | ||
| Dermatosis papulosa nigra | 626 | ||
| Stucco keratosis | 626 | ||
| Hyperkeratosis lenticularis perstans (Flegel’s disease) | 627 | ||
| Benign lichenoid keratoses (lichen planus-like keratosis) | 627 | ||
| Arsenical keratoses | 627 | ||
| Nonmelanoma skin cancers and their precursors | 628 | ||
| Actinic keratosis (solar keratosis) | 629 | ||
| Cutaneous horn (cornu cutaneum) | 631 | ||
| Keratoacanthoma | 631 | ||
| Keratoacanthoma centrifugum marginatum | 632 | ||
| Basal cell carcinoma | 633 | ||
| Topical therapy | 637 | ||
| Nevoid basal cell carcinoma syndrome (Gorlin syndrome) | 637 | ||
| Treatment | 639 | ||
| Squamous cell carcinoma | 639 | ||
| Prevention/treatment | 641 | ||
| Verrucous carcinoma (carcinoma cuniculatum) | 641 | ||
| Bowen’s disease (squamous cell carcinoma in situ) | 642 | ||
| Treatment | 643 | ||
| Erythroplasia of Queyrat | 643 | ||
| Balanitis plasmacellularis (Zoon’s balanitis) | 644 | ||
| Pseudoepitheliomatous keratotic and micaceous balanitis | 645 | ||
| Paget’s disease of the breast | 645 | ||
| Treatment | 645 | ||
| Extramammary Paget’s disease | 646 | ||
| Clear cell papulosis | 648 | ||
| Merkel cell carcinoma (trabecular carcinoma) | 648 | ||
| Sebaceous nevi and tumors | 650 | ||
| Nevus sebaceus (organoid nevus) | 650 | ||
| Sebaceous hyperplasia | 651 | ||
| Muir–Torre syndrome | 652 | ||
| Sweat gland tumors | 653 | ||
| Syringoma | 653 | ||
| Hidrocystomas | 654 | ||
| Malignant acrospiroma (malignant poroma, porocarcinoma) | 655 | ||
| Spiradenoma | 656 | ||
| Cylindroma | 656 | ||
| Malignant mixed tumor (malignant chondroid syringoma) | 657 | ||
| Ceruminoma | 657 | ||
| Hidradenoma papilliferum | 657 | ||
| Syringadenoma papilliferum (syringocystadenoma papilliferum) | 658 | ||
| Papillary eccrine adenoma (tubular apocrine adenoma) | 658 | ||
| Syringofibroadenoma (acrosyringeal nevus of Weedon and Lewis) | 658 | ||
| Microcystic adnexal carcinoma (sclerosing sweat duct carcinoma) | 659 | ||
| Mucinous carcinoma | 659 | ||
| Aggressive digital papillary adenocarcinoma (digital papillary adenocarcinoma) | 660 | ||
| Primary cutaneous adenoid cystic carcinoma | 660 | ||
| Apocrine gland carcinoma | 660 | ||
| Hair follicle nevi and tumors | 660 | ||
| Malignant pilomatricoma (pilomatrix carcinoma, pilomatrical carcinoma) | 661 | ||
| Trichofolliculoma | 661 | ||
| Trichoblastoma | 662 | ||
| Trichilemmoma and Cowden syndrome (Cowden’s disease, multiple hamartoma syndrome) | 663 | ||
| Trichilemmal carcinoma | 664 | ||
| Trichodiscoma, fibrofolliculoma, perifollicular fibromas, mantleomas and Birt–Hogg–Dubé syndrome | 665 | ||
| Tumors of the follicular infundibulum | 666 | ||
| Epithelial cysts and sinuses | 667 | ||
| Proliferating epidermoid cyst | 668 | ||
| Proliferating trichilemmal cyst/malignant trichilemmal cyst | 668 | ||
| Dermoid cyst | 669 | ||
| Pilonidal sinus | 669 | ||
| Steatocystoma simplex | 670 | ||
| Steatocystoma multiplex | 670 | ||
| Eruptive vellus hair cysts | 671 | ||
| Milia | 671 | ||
| Pseudocyst of the auricle (auricular endochondral pseudocyst) | 672 | ||
| Congenital preauricular fistula | 673 | ||
| Chapter 30: Melanocytic Nevi and Neoplasms | 675 | ||
| Epidermal melanocytic lesions | 675 | ||
| Nevus spilus | 675 | ||
| Peutz–Jeghers syndrome | 677 | ||
| Becker nevus | 677 | ||
| Melanoacanthoma | 677 | ||
| Benign melanocytic nevi | 678 | ||
| Treatment | 679 | ||
| Pseudomelanoma (recurrent nevus) | 679 | ||
| Balloon cell nevus | 680 | ||
| Halo nevus | 680 | ||
| Small and medium-sized congenital nevocytic nevus | 681 | ||
| Spindle and epithelioid cell nevus (benign juvenile melanoma, Spitz nevus) | 681 | ||
| Dysplastic nevus | 683 | ||
| Epidermolysis bullosa-associated nevus | 684 | ||
| Melanoma (malignant melanoma) | 685 | ||
| Treatment | 690 | ||
| Dermal melanocytic lesions | 691 | ||
| Mongolian spot | 691 | ||
| Nevus of Ito | 692 | ||
| Treatment | 693 | ||
| Chapter 31: Macrophage/Monocyte Disorders | 694 | ||
| Palisaded granulomatous dermatoses | 694 | ||
| Treatment | 696 | ||
| Annular elastolytic giant cell granuloma (Meischer’s) and actinic granuloma (O’Brien) | 698 | ||
| Interstitial granulomatous drug reaction | 699 | ||
| Granuloma multiforme (Leiker) | 699 | ||
| Necrobiotic xanthogranuloma | 699 | ||
| Sarcoidosis | 700 | ||
| Treatment | 705 | ||
| Histiocytoses | 707 | ||
| Non-X histiocytoses | 707 | ||
| Juvenile xanthogranuloma | 707 | ||
| Benign cephalic histiocytosis | 710 | ||
| Generalized eruptive histiocytoma (generalized eruptive histiocytosis) | 710 | ||
| Xanthoma disseminatum (Montgomery syndrome) | 711 | ||
| Progressive nodular histiocytosis | 711 | ||
| Papular xanthoma | 711 | ||
| Erdheim–Chester disease | 711 | ||
| Progressive mucinous histiocytosis in women | 712 | ||
| Multicentric reticulohistiocytosis | 712 | ||
| Indeterminate cell histiocytosis | 713 | ||
| Sea-blue histiocytosis | 714 | ||
| Congenital self-healing reticulohistiocytosis (Hashimoto–Pritzker disease) | 715 | ||
| Differential diagnosis | 718 | ||
| Chapter 32: Cutaneous Lymphoid Hyperplasia, Cutaneous T-cell Lymphoma, Other Malignant Lymphomas, and Allied Diseases | 720 | ||
| Cutaneous lymphoid hyperplasia (lymphocytoma cutis, lymphadenosis benigna cutis, pseudolymphoma) | 720 | ||
| Jessner lymphocytic infiltrate of the skin | 721 | ||
| Cutaneous lymphomas | 721 | ||
| Fusion toxin | 727 | ||
| Sézary syndrome | 728 | ||
| Granulomatous slack skin | 728 | ||
| Lymphomatoid papulosis | 729 | ||
| Pityriasis lichenoides chronica | 730 | ||
| Blastic plasmacytoid dendritic cell neoplasm (blastic NK-cell lymphoma, CD4, CD56+ hematodermic neoplasm) | 732 | ||
| Cutaneous B-cell lymphoma | 733 | ||
| Intravascular large B-cell lymphoma (malignant “angioendotheliomatosis,” angiotropic large-cell lymphoma) | 735 | ||
| Hodgkin disease | 736 | ||
| Malignant histiocytosis (histiocytic medullary reticulosis) | 736 | ||
| Leukemia cutis | 736 | ||
| Nonspecific conditions associated with leukemia (leukemids) | 738 | ||
| Cutaneous myelofibrosis | 738 | ||
| Hypereosinophilic syndrome | 738 | ||
| Angioimmunoblastic lymphadenopathy with dysproteinemia (angioimmunoblastic T-cell lymphoma) | 739 | ||
| Sinus histiocytosis with massive lymphadenopathy (Rosai–Dorfman disease) | 739 | ||
| Polycythemia vera (erythremia) | 740 | ||
| Chapter 33: Diseases of the Skin Appendages | 741 | ||
| Diseases of the hair | 741 | ||
| Prognosis | 743 | ||
| Telogen effluvium | 743 | ||
| Anagen effluvium | 745 | ||
| Female-pattern alopecia (androgenetic alopecia in women) | 747 | ||
| Trichotillomania (trichotillosis) | 747 | ||
| Other forms of noncicatricial alopecia | 748 | ||
| Atrichia with papular lesions | 754 | ||
| Hair color | 754 | ||
| Hair structure defects | 755 | ||
| Hair casts (pseudonits) | 755 | ||
| Pili torti | 755 | ||
| Menkes kinky hair syndrome | 755 | ||
| Uncombable hair syndrome | 756 | ||
| Plica neuropathica (felted hair) | 758 | ||
| Pseudofolliculitis barbae | 758 | ||
| Pili bifurcati | 759 | ||
| Trichostasis spinulosa | 759 | ||
| Hypertrichosis | 760 | ||
| Generalized or patterned acquired hypertrichosis | 761 | ||
| Hirsutism | 761 | ||
| Treatment | 762 | ||
| Trichomycosis axillaris | 763 | ||
| Associated hair follicle diseases | 763 | ||
| Pityriasis amiantacea (tinea amiantacea) | 763 | ||
| Folliculitis nares perforans | 764 | ||
| Acquired perforating dermatosis | 764 | ||
| Reactive perforating collagenosis | 764 | ||
| Traumatic anserine folliculosis | 765 | ||
| Erythromelanosis follicularis faciei et colli | 765 | ||
| Disseminate and recurrent infundibulofolliculitis | 765 | ||
| Lichen spinulosus | 765 | ||
| Disorders of the sweat glands | 765 | ||
| Surgical treatment | 766 | ||
| Anhidrosis (hypohidrosis) | 767 | ||
| Bromhidrosis | 767 | ||
| Chromhidrosis | 768 | ||
| Fox–Fordyce disease | 768 | ||
| Granulosis rubra nasi | 768 | ||
| Recurrent palmoplantar hidradenitis | 769 | ||
| Diseases of the nails | 769 | ||
| Lichen planus of nails | 769 | ||
| Psoriatic nails | 770 | ||
| Darier’s disease | 771 | ||
| Clubbing | 771 | ||
| Shell nail syndrome | 771 | ||
| Koilonychia (spoon nails) | 771 | ||
| Congenital onychodysplasia of the index fingers | 771 | ||
| Trachyonychia | 772 | ||
| Onychauxis | 772 | ||
| Onychogryphosis | 772 | ||
| Onychophosis | 772 | ||
| Anonychia | 772 | ||
| Onychoatrophy | 772 | ||
| Onychomadesis | 772 | ||
| Beau’s lines | 773 | ||
| Half and half nails | 773 | ||
| Muehrcke’s lines | 773 | ||
| Mees’ lines | 773 | ||
| Terry nails | 774 | ||
| Onychorrhexis (brittle nails) | 774 | ||
| Onychoschizia | 774 | ||
| Stippled nails | 774 | ||
| Racquet nails (nail en raquette) | 775 | ||
| Chevron nail (herringbone nail) | 775 | ||
| Hapalonychia | 775 | ||
| Platonychia | 775 | ||
| Nail–patella syndrome (hereditary osteo-onychodysplasia, Fong syndrome) | 775 | ||
| Onychophagia | 775 | ||
| Onychotillomania | 775 | ||
| Onycholysis | 776 | ||
| Median nail dystrophy (dystrophia unguis mediana canaliformis, solenonychia) | 776 | ||
| Pterygium unguis | 776 | ||
| Pterygium inversum unguis | 776 | ||
| Hangnail | 777 | ||
| Pincer nails | 777 | ||
| Retronychia | 777 | ||
| Nail discolorations | 778 | ||
| Leukonychia or white nails | 778 | ||
| Longitudinal erythronychia | 778 | ||
| Melanonychia | 778 | ||
| Green nails | 779 | ||
| Staining of the nail plate | 779 | ||
| Red lunulae | 779 | ||
| Spotted lunulae | 780 | ||
| Purpura of the nail beds | 780 | ||
| Blue nails | 780 | ||
| Yellow nail syndrome | 780 | ||
| Neoplasms of the nailbed | 780 | ||
| Chapter 34: Disorders of the Mucous Membranes | 783 | ||
| Cheilitis | 783 | ||
| Cheilitis exfoliativa | 783 | ||
| Allergic contact cheilitis | 783 | ||
| Actinic cheilitis | 783 | ||
| Cheilitis glandularis | 784 | ||
| Angular cheilitis | 785 | ||
| Plasmoacanthoma | 785 | ||
| Drug-induced ulcer of the lip | 785 | ||
| Oral and cutaneous Crohn’s disease | 785 | ||
| Pyostomatitis vegetans | 786 | ||
| Cheilitis granulomatosa | 786 | ||
| Melkersson–Rosenthal syndrome | 787 | ||
| Fordyce’s disease (Fordyce spots) | 787 | ||
| Stomatitis nicotina | 787 | ||
| Torus palatinus | 788 | ||
| Fissured tongue | 788 | ||
| Geographic tongue | 788 | ||
| Black hairy tongue | 789 | ||
| Smooth tongue | 789 | ||
| Eruptive lingual papillitis | 789 | ||
| Median rhomboid glossitis | 790 | ||
| Eosinophilic ulcer of the oral mucosa | 790 | ||
| Caviar tongue | 790 | ||
| Cutaneous sinus of dental origin (dental sinus) | 790 | ||
| Neoplasms | 791 | ||
| Squamous cell carcinoma | 793 | ||
| Acquired dyskeratotic leukoplakia | 793 | ||
| White sponge nevus | 794 | ||
| Melanocytic oral lesions | 794 | ||
| Melanosis | 794 | ||
| Osseous choristoma of the tongue | 795 | ||
| Peripheral ameloblastoma | 795 | ||
| Trumpeter’s wart | 795 | ||
| Epulis | 795 | ||
| Pyogenic granuloma | 795 | ||
| Granuloma fissuratum | 795 | ||
| Angina bullosa haemorrhagica | 795 | ||
| Mucocele | 795 | ||
| Acute necrotizing ulcerative gingivostomatitis (trench mouth, Vincent’s disease) | 796 | ||
| Acatalasemia | 796 | ||
| Cyclic neutropenia | 796 | ||
| Recurrent intraoral herpes simplex infection | 797 | ||
| Recurrent aphthous stomatitis (canker sores, aphthosis) | 797 | ||
| Treatment | 798 | ||
| Major aphthous ulcer (periadenitis mucosa necrotica recurrens) | 799 | ||
| Behçet syndrome (oculo-oral-genital syndrome) | 799 | ||
| Treatment | 800 | ||
| Chapter 35: Cutaneous Vascular Diseases | 801 | ||
| Raynaud phenomenon and Raynaud’s disease | 801 | ||
| Treatment | 802 | ||
| Erythromelalgia | 803 | ||
| Red ear syndrome | 804 | ||
| Livedo reticularis, livedo racemosa | 805 | ||
| Cholesterol emboli | 806 | ||
| Livedoid vasculopathy | 807 | ||
| Calciphylaxis | 808 | ||
| Marshall–White syndrome and Bier spots | 809 | ||
| Purpura | 809 | ||
| Immune thrombocytopenic purpura (immune thrombocytopenia) | 810 | ||
| Drug-induced thrombocytopenia | 811 | ||
| Thrombotic microangiopathy | 811 | ||
| Hemolytic uremic syndrome | 812 | ||
| Nonthrombocytopenic purpura (dysproteinemic purpura) | 813 | ||
| Cryoglobulinemia and cryofibrinogenemia | 813 | ||
| Waldenström hyperglobulinemic purpura (purpura hyperglobulinemica) | 814 | ||
| Waldenström macroglobulinemia | 814 | ||
| Purpura secondary to clotting disorders | 815 | ||
| Drug- and food-induced purpura | 815 | ||
| Purpura fulminans | 816 | ||
| Disseminated intravascular coagulation | 817 | ||
| Congenital fibrinogen disorders | 817 | ||
| Blueberry muffin baby | 817 | ||
| Miscellaneous purpuric manifestations | 818 | ||
| Deep venous thrombosis | 818 | ||
| Mondor’s disease | 818 | ||
| Obstructive or traumatic purpura | 819 | ||
| Paroxysmal nocturnal hemoglobinuria (PNH) | 820 | ||
| Paroxysmal hand hematoma (Achenbach syndrome) | 820 | ||
| Easy bruising syndromes | 820 | ||
| Painful bruising syndrome (autoerythrocyte sensitization, Gardner–Diamond syndrome, psychogenic purpura) | 820 | ||
| Pigmentary purpuric eruptions (progressive pigmentary dermatosis, progressive pigmenting purpura, purpura pigmentosa chronica) | 821 | ||
| Purpuric agave dermatitis | 822 | ||
| Vasculitis | 822 | ||
| Classification | 822 | ||
| Small-vessel vasculitis | 822 | ||
| Treatment | 824 | ||
| Cutaneous vasculitis and connective tissue disease | 824 | ||
| Subtypes of small-vessel vasculitis | 824 | ||
| Henoch–Schönlein purpura | 824 | ||
| Acute hemorrhagic edema of infancy | 825 | ||
| Urticarial vasculitis | 826 | ||
| Cryoglobulinemic vasculitis | 827 | ||
| Golfer’s and exercise-related “vasculitis” | 827 | ||
| Erythema elevatum diutinum | 827 | ||
| Granuloma faciale | 828 | ||
| Polyarteritis nodosa | 829 | ||
| Cutaneous polyarteritis nodosa | 830 | ||
| ANCA-positive small-vessel vasculitides | 830 | ||
| Microscopic polyangiitis | 831 | ||
| Wegener granulomatosis | 831 | ||
| Churg–Strauss syndrome | 832 | ||
| Cocaine-associated vasculitis | 833 | ||
| Giant-cell arteritis/temporal arteritis | 833 | ||
| Takayasu arteritis | 834 | ||
| Malignant atrophic papulosis | 834 | ||
| Thromboangiitis obliterans (Buerger’s disease) | 835 | ||
| Arteriosclerosis obliterans | 836 | ||
| Diffuse dermal angiomatosis | 836 | ||
| Mucocutaneous lymph node syndrome (Kawasaki’s disease) | 837 | ||
| Treatment | 838 | ||
| Telangiectasia | 838 | ||
| Generalized essential telangiectasia | 838 | ||
| Unilateral nevoid telangiectasia | 839 | ||
| Hereditary hemorrhagic telangiectasia (Osler’s disease) | 839 | ||
| Leg ulcers | 840 | ||
| Venous diseases of the extremities | 840 | ||
| Arterial insufficiency (ischemic) ulcer | 842 | ||
| Neuropathic ulcers | 842 | ||
| Lymphedema | 843 | ||
| Treatment | 845 | ||
| Chapter 36: Disturbances of Pigmentation | 846 | ||
| Pigmentary demarcation lines | 846 | ||
| Abnormal pigmentation | 846 | ||
| Postinflammatory hyperpigmentation (postinflammatory pigmentary alteration—PIPA) | 846 | ||
| Melasma (chloasma) | 847 | ||
| Pigmented anomalies of the extremities | 848 | ||
| Dyschromatosis symmetrica hereditaria (DSH) (reticulate acropigmentation of Dohi) | 849 | ||
| Dyschromatosis universalis hereditaria (DUH) | 849 | ||
| Galli–Galli disease | 849 | ||
| Reticulate acropigmentation of Kitamura | 850 | ||
| Dermatopathia pigmentosa reticularis | 850 | ||
| Transient neonatal pustular melanosis | 850 | ||
| Peutz–Jeghers syndrome | 851 | ||
| Riehl melanosis | 851 | ||
| Tar melanosis (melanodermatitis toxica lichenoides) | 852 | ||
| Familial progressive hyperpigmentation | 852 | ||
| Periorbital hyperpigmentation | 852 | ||
| Metallic discolorations | 852 | ||
| Arsenic | 852 | ||
| Hemochromatosis | 853 | ||
| Titanium | 854 | ||
| Canthaxanthin | 854 | ||
| Idiopathic guttate hypomelanosis (leukopathia symmetrica progressiva) | 854 | ||
| Vitiligo | 854 | ||
| Chemical leukoderma (occupational vitiligo) | 857 | ||
| Vogt–Koyanagi–Harada syndrome | 858 | ||
| Alezzandrini syndrome | 859 | ||
| Leukoderma | 859 | ||
| Oculocutaneous albinism | 859 | ||
| Disorders of melanocyte transport | 861 | ||
| Griscelli syndrome | 861 | ||
| Cross–McKusick–Breen syndrome | 862 | ||
| Chapter 37: Dermatologic Surgery | 863 | ||
| Anticoagulants | 863 | ||
| Antibiotic prophylaxis | 863 | ||
| Endocarditis prophylaxis | 865 | ||
| Preoperative antisepsis | 865 | ||
| Anesthesia | 866 | ||
| Side effects | 866 | ||
| Anatomy A thorough understanding of anatomy is critical when performing dermatologic surgery. The vascular supply, sensory ... | 867 | ||
| Biopsies | 869 | ||
| Suture technique | 870 | ||
| Cryosurgery | 872 | ||
| Curettage | 875 | ||
| Electrosurgery | 875 | ||
| Electrosection | 876 | ||
| Excisional technique | 877 | ||
| Skin flaps and grafts | 878 | ||
| Skin grafts | 881 | ||
| Mohs micrographic surgery | 884 | ||
| Photodynamic therapy | 885 | ||
| Squamous cell carcinoma in situ | 886 | ||
| Radiation therapy for skin cancer | 886 | ||
| Chapter 38: Cutaneous Laser Surgery | 888 | ||
| Laser principles | 888 | ||
| Laser treatment of vascular lesions | 891 | ||
| Intense pulsed light | 893 | ||
| Laser treatment for pigmented lesions | 893 | ||
| Tattoo complications | 896 | ||
| Laser hair removal | 897 | ||
| Ablative laser resurfacing | 898 | ||
| Fractional resurfacing | 898 | ||
| Chapter 39: Cosmetic Dermatology | 900 | ||
| Soft-tissue augmentation | 900 | ||
| Expanded polytetrafluoroethylene | 903 | ||
| Botulinum toxin | 903 | ||
| Hyperhidrosis | 905 | ||
| Varicose and telangiectatic veins | 906 | ||
| Endovenous ablation | 908 | ||
| Liposuction | 909 | ||
| Chemical peels | 909 | ||
| Deep peel | 910 | ||
| Index | 911 |