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Book Details
Abstract
Renal Physiology helps you to quickly and easily grasp the fundamentals of renal physiology and learn how to apply them in a clinical context. Thoroughly updated, this medical reference book in the Mosby Physiology Monograph Series provides a basic understanding of normal kidney function at the cellular and molecular level. Attractively illustrated with clear 2-color diagrams, it also facilitates study with learning objectives, "In the Clinic" and "At the Molecular Level" boxes, chapter summaries, and clinical cases with review questions and explained answers.
- Stay current with clear, accurate coverage of the physiology of normal renal function focusing on the needs of the student.
- Bridge the gap between normal function and disease with pathophysiology content throughout the book.
- Understand complex concepts by examining more than more than 250 clear, 2-color diagrams.
- Perform quick searches ... add your own notes and bookmarks ... and more!
- Put theory into practice with "In the Clinic" or "At the Molecular Level " boxes in each chapter that explain the practical applications of fundamental knowledge.
- Deepen your understanding of fundamental and advanced information with an expanded collection of review questions reviewed and reorganized by chapter.
- Master the material more easily with learning objectives, overview boxes, key words and concepts, and chapter summaries.
- Apply what you've learned to real-life clinical situations with clinical cases in question-answer format at the end of each chapter.
Table of Contents
Section Title | Page | Action | Price |
---|---|---|---|
Front Cover | Cover | ||
Renal Physiology | iii | ||
Copyright | iv | ||
Dedication | v | ||
Preface | vii | ||
Acknowledgments | ix | ||
Contents | xi | ||
CHAPTER 1 - PHYSIOLOGY OF BODY FLUIDS | 1 | ||
PHYSICOCHEMICAL PROPERTIES OF ELECTROLYTE SOLUTIONS | 1 | ||
VOLUMES OF BODY FLUID COMPARTMENTS | 4 | ||
COMPOSITION OF BODY FLUID COMPARTMENTS | 6 | ||
FLUID EXCHANGE BETWEEN BODY FLUID COMPARTMENTS | 7 | ||
SUMMARY | 12 | ||
CHAPTER 2 - STRUCTURE AND FUNCTION OF THE KIDNEYS | 15 | ||
STRUCTURE OF THE KIDNEYS | 15 | ||
SUMMARY | 25 | ||
CHAPTER 3 - GLOMERULAR FILTRATION AND RENAL BLOOD FLOW | 27 | ||
RENAL CLEARANCE | 27 | ||
GLOMERULAR FILTRATION | 31 | ||
RENAL BLOOD FLOW | 33 | ||
REGULATION OF RENAL BLOOD FLOW AND GLOMERULAR FILTRATION RATE | 36 | ||
SUMMARY | 42 | ||
CHAPTER 4 - RENAL TRANSPORT MECHANISMS: NACL AND WATER REABSORPTION ALONG THE NEPHRON | 45 | ||
GENERAL PRINCIPLES OF MEMBRANE TRANSPORT | 46 | ||
GENERAL PRINCIPLES OF TRANSEPITHELIAL SOLUTE AND WATER TRANSPORT | 49 | ||
NACL, SOLUTE, AND WATER REABSORPTION ALONG THE NEPHRON | 50 | ||
REGULATION OF NACL AND WATER REABSORPTION | 62 | ||
SUMMARY | 70 | ||
CHAPTER 5 - REGULATION OF BODY FLUID OSMOLALITY: REGULATION OF WATER BALANCE | 73 | ||
ARGININE VASOPRESSIN | 75 | ||
THIRST | 82 | ||
RENAL MECHANISMS FOR DILUTION AND CONCENTRATION OF THE URINE | 82 | ||
ASSESSMENT OF RENAL DILUTING AND CONCENTRATING ABILITY | 89 | ||
SUMMARY | 91 | ||
CHAPTER 6 - REGULATION OF EXTRACELLULAR FLUID VOLUME AND NACL BALANCE | 93 | ||
CONCEPT OF EFFECTIVE CIRCULATING VOLUME | 95 | ||
VOLUME-SENSING SYSTEMS | 96 | ||
CONTROL OF RENAL NACL EXCRETION DURING EUVOLEMIA | 103 | ||
CONTROL OF NA+ EXCRETION WITH VOLUME EXPANSION | 105 | ||
CONTROL OF NA+ EXCRETION WITH VOLUME CONTRACTION | 107 | ||
EDEMA | 109 | ||
SUMMARY | 112 | ||
CHAPTER 7 - REGULATION OF POTASSIUM BALANCE | 115 | ||
OVERVIEW OF K+ HOMEOSTASIS | 115 | ||
REGULATION OF PLASMA [K+] | 117 | ||
ALTERATIONS OF PLASMA [K+] | 119 | ||
K+ EXCRETION BY THE KIDNEYS | 120 | ||
CELLULAR MECHANISMS OF K+ TRANSPORT BY PRINCIPAL CELLS AND INTERCALATED CELLS IN THE DISTAL TUBULE AND COLLECTING DUCT | 122 | ||
REGULATION OF K+ SECRETION BY THE DISTAL TUBULE AND COLLECTING DUCT | 123 | ||
FACTORS THAT PERTURB K+ EXCRETION | 125 | ||
SUMMARY | 130 | ||
CHAPTER 8 - REGULATION OF ACID-BASE BALANCE | 131 | ||
HCO−3 BUFFER SYSTEM | 132 | ||
OVERVIEW OF ACID-BASE BALANCE | 132 | ||
RENAL NET ACID EXCRETION | 134 | ||
HCO−3 REABSORPTION ALONG THE NEPHRON | 135 | ||
REGULATION OF H+ SECRETION | 138 | ||
FORMATION OF NEW HCO−3 | 139 | ||
RESPONSE TO ACID-BASE DISORDERS | 143 | ||
SIMPLE ACID-BASE DISORDERS | 146 | ||
ANALYSIS OF ACID-BASE DISORDERS | 148 | ||
SUMMARY | 150 | ||
CHAPTER 9 - REGULATION OF CALCIUM AND PHOSPHATE HOMEOSTASIS | 153 | ||
CALCIUM | 154 | ||
PHOSPHATE | 160 | ||
INTEGRATIVE REVIEW OF PARATHYROID HORMONE AND CALCITRIOL ON CA++ AND PI HOMEOSTASIS | 164 | ||
SUMMARY | 165 | ||
CHAPTER 10 - PHYSIOLOGY OF DIURETIC ACTION | 167 | ||
GENERAL PRINCIPLES OF DIURETIC ACTION | 168 | ||
DIURETIC BRAKING PHENOMENON | 169 | ||
MECHANISMS OF ACTION OF DIURETICS | 171 | ||
EFFECT OF DIURETICS ON THE EXCRETION OF WATER AND SOLUTES | 173 | ||
SUMMARY | 176 | ||
ADDITIONAL READING | 179 | ||
APPENDIX A - INTEGRATIVE CASE STUDIES | 181 | ||
CASE 1 | 181 | ||
CASE 2 | 181 | ||
CASE 3 | 182 | ||
CASE 4 | 182 | ||
CASE 5 | 183 | ||
CASE 6 | 183 | ||
CASE 7 | 183 | ||
CASE 8 | 183 | ||
CASE 9 | 184 | ||
CASE 10 | 184 | ||
APPENDIX B - NORMAL LABORATORY VALUES | 185 | ||
APPENDIX C - NEPHRON FUNCTION | 187 | ||
APPENDIX D - ANSWERS TO SELF-STUDY PROBLEMS | 191 | ||
CHAPTER 1 | 191 | ||
CHAPTER 2 | 193 | ||
CHAPTER 3 | 194 | ||
CHAPTER 4 | 195 | ||
CHAPTER 5 | 197 | ||
CHAPTER 6 | 198 | ||
CHAPTER 7 | 199 | ||
CHAPTER 8 | 200 | ||
CHAPTER 9 | 201 | ||
CHAPTER 10 | 201 | ||
APPENDIX E - ANSWERS TO INTEGRATIVE CASE STUDIES | 205 | ||
CASE 1 | 205 | ||
CASE 2 | 206 | ||
CASE 3 | 207 | ||
CASE 4 | 208 | ||
CASE 5 | 209 | ||
CASE 6 | 210 | ||
CASE 7 | 210 | ||
CASE 8 | 210 | ||
CASE 9 | 211 | ||
CASE 10 | 211 | ||
APPENDIX F - REVIEW EXAMINATION | 213 | ||
CHAPTER 2 | 213 | ||
CHAPTER 3 | 214 | ||
CHAPTER 4 | 215 | ||
CHAPTER 5 | 216 | ||
CHAPTER 6 | 217 | ||
CHAPTER 7 | 219 | ||
CHAPTER 8 | 220 | ||
CHAPTER 9 | 222 | ||
CHAPTER 10 | 222 | ||
INDEX | 227 |