BOOK
Advances in Laminitis, Part I, An Issue of Veterinary Clinics: Equine Practice - E-Book
(2010)
Additional Information
Book Details
Abstract
Articles include: The Anatomy and Physiology of the Lamellar, Dermal-Epidermal Interface, Carbohydrate Alimentary Overload Laminitis, Events in the Hindgut, Therapeutic Hypothermia (cryotherapy) to Prevent and Treat Acute Laminitis, Acute Laminits: Supportive Medical Therapy, First Aid for the Foot: Therapeutic and Mechanical Support, Serial Venography after Carbohydrate-Induced Laminitis, Venography and Its Clinical Application in North America, Chronic Laminitis: Strategic Hoof Wall Resection, The Laminar Wedge of Chronic Laminitis, Lysis of the Distal Phalanx in Chronic Laminitis, Chronic Laminitis Foot Support: Clogs, Homecare for the Chronic Laminitis Case, The Pharmacological Basis for the Treatment of Developmental and Acute Laminitis, and Black Walnut Extract Laminitis: An Inflammatory Model.
Table of Contents
| Section Title | Page | Action | Price |
|---|---|---|---|
| Front Cover | Cover | ||
| Contributors | iii | ||
| Contents | vii | ||
| Preface | xv | ||
| Chapter 1. A Historical Perspective of Laminitis | 1 | ||
| ANCIENT HISTORY | 1 | ||
| ROMAN EMPIRE (27 BC TO 500 AD) | 2 | ||
| DARK AGES (500 TO 900) | 2 | ||
| HIGH MIDDLE AGES (900 TO 1450) | 2 | ||
| AGE OF DISCOVERY (1450 TO 1700) | 3 | ||
| MODERN ERA (1700 TO 1949) | 3 | ||
| POSTMODERN (1949 TO PRESENT) | 6 | ||
| REFERENCES | 7 | ||
| Chapter 2. 80 Causes, Predispositions, and Pathways of Laminitis | 13 | ||
| REFERENCES | 16 | ||
| Chapter 3. Laminitis Treatment: A Personal Memoir | 21 | ||
| Chapter 4. The Anatomy and Physiology of the Suspensory Apparatus of the Distal Phalanx | 29 | ||
| HOOF WALL GROWTH | 30 | ||
| HOOF WALL TUBULES | 33 | ||
| THE CORIUM | 35 | ||
| THE CORONET CORIUM | 36 | ||
| THE SOLE CORIUM | 37 | ||
| THE BLOOD SUPPLY OF THE FOOT | 37 | ||
| THE INNER HOOF WALL | 41 | ||
| THE DERMAL MICROCIRCULATION | 41 | ||
| SECONDARY EPIDERMAL LAMELLAE | 41 | ||
| THE BM | 44 | ||
| HDS | 45 | ||
| LAMELLAR REMODELING ENZYMES | 47 | ||
| REFERENCES | 47 | ||
| Chapter 5. Overview of Current Laminitis Research | 51 | ||
| CHARACTERIZATION OF LESIONS | 52 | ||
| INFLAMMATION | 53 | ||
| ENZYMATIC DYSREGULATION | 56 | ||
| METABOLIC SYNDROME | 57 | ||
| ALTERATION OF ENDOTHELIAL AND VENOUS FUNCTION | 58 | ||
| SUMMARY | 59 | ||
| REFERENCES | 59 | ||
| Chapter 6. Carbohydrate Alimentary Overload Laminitis | 65 | ||
| ALIMENTARY CARBOHYDRATE OVERLOAD MODEL | 66 | ||
| LAMINITIS HISTOPATHOOGY | 68 | ||
| GRADE 1 LAMINITIS HISTOPATHOLOGY | 69 | ||
| GRADE 2 LAMINITIS HISTOPATHOLOGY | 71 | ||
| GRADE 3 LAMINITIS HISTOPATHOLOGY | 71 | ||
| SUMMARY | 76 | ||
| REFERENCES | 76 | ||
| Chapter 7. Microbial Events in the Hindgut During Carbohydrate-induced Equine Laminitis | 79 | ||
| THE DEVELOPMENT OF EXPERIMENTAL MODELS FOR INDUCING EQUINE LAMINITIS | 80 | ||
| TRADITIONAL MICROBIOLOGICAL STUDIES OF THE EQUINE HINDGUT MICROBIOME DURING LAMINITIS DEVELOPMENT | 82 | ||
| MODERN MOLECULAR MICROBIAL ECOLOGY TOOLS AND THEIR APPLICATION TO LAMINITIS | 86 | ||
| SUMMARY | 90 | ||
| REFERENCES | 91 | ||
| Chapter 8. Black Walnut Extract: An Inflammatory Model | 95 | ||
| SUMMARY | 99 | ||
| REFERENCES | 99 | ||
| Chapter 9. Acute Laminitis: Medical and Supportive Therapy | 103 | ||
| INITIAL ASSESSMENT OF THE HORSE WITH ACUTE LAMINITIS | 104 | ||
| INITIAL TREATMENT OF THE HORSE WITH ACUTE LAMINITIS | 106 | ||
| MONITORING PROGRESSION AND FURTHER MANAGEMENT | 109 | ||
| SUMMARY | 111 | ||
| REFERENCES | 112 | ||
| Chapter 10.The Pharmacologic Basis for the Treatment of Developmental and Acute Laminitis | 115 | ||
| EVENTS OCCURRING IN THE DEVELOPMENTAL AND ACUTE STAGES AT WHICH PHARMACOLOGIC THERAPY IS AIMED | 116 | ||
| ENDOTOXEMIA/SIRS | 116 | ||
| POLYMYXIN B | 117 | ||
| HYPERIMMUNE SERUM AGAINST COMPONENTS OF ENDOTOXIN | 117 | ||
| NONSTEROIDAL ANTIINFLAMMATORY DRUGS | 117 | ||
| DYSREGULATION OF LAMINAR MICROVASCULAR BLOOD FLOW | 117 | ||
| PLATELET ACTIVATION/THROMBOSIS | 118 | ||
| BREAKDOWN OF THE LAMINAR BASEMENT MEMBRANE | 118 | ||
| INFLAMMATORY INJURY TO THE LAMINAE | 119 | ||
| NSAIDS | 119 | ||
| INTRAVENOUS LIDOCAINE | 120 | ||
| DISTAL LIMB CRYOTHERAPY | 120 | ||
| PTX | 120 | ||
| FUTURE THERAPIES | 121 | ||
| REFERENCES | 121 | ||
| Chapter 11. Therapeutic Hypothermia (Cryotherapy) to Prevent and Treat Acute Laminitis | 125 | ||
| THE EFFECTS OF HYPOTHERMIA ON TISSUE | 126 | ||
| THERAPEUTIC HYPOTHERMIA OF THE EQUINE DISTAL LIMB | 127 | ||
| USING DIGITAL HYPOTHERMIA TO HELP PREVENT LAMINITIS | 128 | ||
| USING DIGITAL HYPOTHERMIA FOR THE TREATMENT OF ACUTE LAMINITIS | 130 | ||
| REFERENCES | 130 | ||
| Chapter 12. Progression of Venographic Changes After Experimentally Induced Laminitis | 135 | ||
| VENOGRAPHIC TECHNIQUE | 136 | ||
| VENOGRAPHY OF CONTROL (NORMAL) FEET BEFORE OF DOSING | 136 | ||
| VENOGRAPHY 48 HOURS AFTER OF DOSING | 137 | ||
| VENOGRAPHY 7 DAYS AFTER OF DOSING | 138 | ||
| VENOGRAPHY 6 WEEKS AFTER OF DOSING | 138 | ||
| SUMMARY | 140 | ||
| ACKNOWLEDGMENTS | 140 | ||
| REFERENCES | 140 | ||
| Chapter 13. Clinical Presentation, Diagnosis, and Prognosis of Chronic Laminitis in North America | 141 | ||
| CLINICAL PRESENTATION | 141 | ||
| DIAGNOSIS | 147 | ||
| PROGNOSIS | 151 | ||
| SUMMARY | 152 | ||
| REFERENCES | 152 | ||
| Chapter 14. Pathology of the Distal Phalanx in Equine Laminitis: More Than Just Skin Deep | 155 | ||
| ARCHITECTURE OF THE DISTAL PHALANX | 156 | ||
| BONE MICROENVIRONMENT | 159 | ||
| OSTEOIMMUNOLOGY AND INFLAMMATION-INDUCED BONE MODELING | 160 | ||
| BIOMECHANICALLY INDUCED BONE MODELING | 162 | ||
| SUMMARY | 162 | ||
| REFERENCES | 163 | ||
| Chapter 15. Equine Venography and Its Clinical Application in North America | 167 | ||
| PERFORMING THE VENOGRAM | 167 | ||
| THE 6 AREAS OF INTEREST OF THE NORMAL VENOGRAM | 170 | ||
| INTERPRETATION | 170 | ||
| CLINICAL APPLICATION | 172 | ||
| ACKNOWLEDGMENTS | 176 | ||
| REFERENCES | 176 | ||
| Chapter 16. The Lamellar Wedge | 179 | ||
| OVERVIEW | 179 | ||
| PATHOGENESIS OF THE LAMELLAR WEDGE | 179 | ||
| TEMPORAL DEVELOPMENT OF THE LAMELLAR WEDGE | 187 | ||
| HIDDEN DANGERS: PATHOLOGIC CONSEQUENCES OF DP DISLOCATION | 189 | ||
| THE LAMELLAR WEDGE IN THE PASTURE-INDUCED LAMINITIC HORSE | 193 | ||
| SUSCEPTIBILITY TO ONYCHOMYCOSIS | 193 | ||
| SUMMARY | 193 | ||
| REFERENCES | 194 | ||
| Chapter 17. Chronic Laminitis: Strategic Hoof Wal l Resection | 197 | ||
| PERFORMING THE WALL RESECTION | 198 | ||
| AFTERCARE | 202 | ||
| COMPLICATIONS | 203 | ||
| COMPLETE WALL RESECTION WITH DISTAL DISPLACEMENT | 204 | ||
| ACKNOWLEDGMENTS | 204 | ||
| REFERENCES | 204 | ||
| Chapter 18. The Use of the Wooden Shoe (Steward Clog) in Treating Laminitis | 207 | ||
| REFERENCES | 214 | ||
| Chapter 19. Home Care for Horses with Chronic Laminitis | 215 | ||
| PAIN MANAGEMENT | 215 | ||
| CONCURRENT MEDICAL ISSUES | 217 | ||
| NUTRITION | 217 | ||
| REHABILITATION | 219 | ||
| NURSING CARE | 220 | ||
| HOUSING AND FOOTING | 220 | ||
| HOOF CARE | 221 | ||
| ENSURING OWNER COMPLIANCE | 222 | ||
| REFERENCES | 222 | ||
| Index | 225 |