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BOOK
Advances in Laminitis, Part I, An Issue of Veterinary Clinics: Equine Practice - E-Book
(2010)
Additional Information
Book Details
Abstract
Articles include: The Anatomy and Physiology of the Lamellar, Dermal-Epidermal Interface, Carbohydrate Alimentary Overload Laminitis, Events in the Hindgut, Therapeutic Hypothermia (cryotherapy) to Prevent and Treat Acute Laminitis, Acute Laminits: Supportive Medical Therapy, First Aid for the Foot: Therapeutic and Mechanical Support, Serial Venography after Carbohydrate-Induced Laminitis, Venography and Its Clinical Application in North America, Chronic Laminitis: Strategic Hoof Wall Resection, The Laminar Wedge of Chronic Laminitis, Lysis of the Distal Phalanx in Chronic Laminitis, Chronic Laminitis Foot Support: Clogs, Homecare for the Chronic Laminitis Case, The Pharmacological Basis for the Treatment of Developmental and Acute Laminitis, and Black Walnut Extract Laminitis: An Inflammatory Model.
Table of Contents
Section Title | Page | Action | Price |
---|---|---|---|
Front Cover | Cover | ||
Contributors | iii | ||
Contents | vii | ||
Preface | xv | ||
Chapter 1. A Historical Perspective of Laminitis | 1 | ||
ANCIENT HISTORY | 1 | ||
ROMAN EMPIRE (27 BC TO 500 AD) | 2 | ||
DARK AGES (500 TO 900) | 2 | ||
HIGH MIDDLE AGES (900 TO 1450) | 2 | ||
AGE OF DISCOVERY (1450 TO 1700) | 3 | ||
MODERN ERA (1700 TO 1949) | 3 | ||
POSTMODERN (1949 TO PRESENT) | 6 | ||
REFERENCES | 7 | ||
Chapter 2. 80 Causes, Predispositions, and Pathways of Laminitis | 13 | ||
REFERENCES | 16 | ||
Chapter 3. Laminitis Treatment: A Personal Memoir | 21 | ||
Chapter 4. The Anatomy and Physiology of the Suspensory Apparatus of the Distal Phalanx | 29 | ||
HOOF WALL GROWTH | 30 | ||
HOOF WALL TUBULES | 33 | ||
THE CORIUM | 35 | ||
THE CORONET CORIUM | 36 | ||
THE SOLE CORIUM | 37 | ||
THE BLOOD SUPPLY OF THE FOOT | 37 | ||
THE INNER HOOF WALL | 41 | ||
THE DERMAL MICROCIRCULATION | 41 | ||
SECONDARY EPIDERMAL LAMELLAE | 41 | ||
THE BM | 44 | ||
HDS | 45 | ||
LAMELLAR REMODELING ENZYMES | 47 | ||
REFERENCES | 47 | ||
Chapter 5. Overview of Current Laminitis Research | 51 | ||
CHARACTERIZATION OF LESIONS | 52 | ||
INFLAMMATION | 53 | ||
ENZYMATIC DYSREGULATION | 56 | ||
METABOLIC SYNDROME | 57 | ||
ALTERATION OF ENDOTHELIAL AND VENOUS FUNCTION | 58 | ||
SUMMARY | 59 | ||
REFERENCES | 59 | ||
Chapter 6. Carbohydrate Alimentary Overload Laminitis | 65 | ||
ALIMENTARY CARBOHYDRATE OVERLOAD MODEL | 66 | ||
LAMINITIS HISTOPATHOOGY | 68 | ||
GRADE 1 LAMINITIS HISTOPATHOLOGY | 69 | ||
GRADE 2 LAMINITIS HISTOPATHOLOGY | 71 | ||
GRADE 3 LAMINITIS HISTOPATHOLOGY | 71 | ||
SUMMARY | 76 | ||
REFERENCES | 76 | ||
Chapter 7. Microbial Events in the Hindgut During Carbohydrate-induced Equine Laminitis | 79 | ||
THE DEVELOPMENT OF EXPERIMENTAL MODELS FOR INDUCING EQUINE LAMINITIS | 80 | ||
TRADITIONAL MICROBIOLOGICAL STUDIES OF THE EQUINE HINDGUT MICROBIOME DURING LAMINITIS DEVELOPMENT | 82 | ||
MODERN MOLECULAR MICROBIAL ECOLOGY TOOLS AND THEIR APPLICATION TO LAMINITIS | 86 | ||
SUMMARY | 90 | ||
REFERENCES | 91 | ||
Chapter 8. Black Walnut Extract: An Inflammatory Model | 95 | ||
SUMMARY | 99 | ||
REFERENCES | 99 | ||
Chapter 9. Acute Laminitis: Medical and Supportive Therapy | 103 | ||
INITIAL ASSESSMENT OF THE HORSE WITH ACUTE LAMINITIS | 104 | ||
INITIAL TREATMENT OF THE HORSE WITH ACUTE LAMINITIS | 106 | ||
MONITORING PROGRESSION AND FURTHER MANAGEMENT | 109 | ||
SUMMARY | 111 | ||
REFERENCES | 112 | ||
Chapter 10.The Pharmacologic Basis for the Treatment of Developmental and Acute Laminitis | 115 | ||
EVENTS OCCURRING IN THE DEVELOPMENTAL AND ACUTE STAGES AT WHICH PHARMACOLOGIC THERAPY IS AIMED | 116 | ||
ENDOTOXEMIA/SIRS | 116 | ||
POLYMYXIN B | 117 | ||
HYPERIMMUNE SERUM AGAINST COMPONENTS OF ENDOTOXIN | 117 | ||
NONSTEROIDAL ANTIINFLAMMATORY DRUGS | 117 | ||
DYSREGULATION OF LAMINAR MICROVASCULAR BLOOD FLOW | 117 | ||
PLATELET ACTIVATION/THROMBOSIS | 118 | ||
BREAKDOWN OF THE LAMINAR BASEMENT MEMBRANE | 118 | ||
INFLAMMATORY INJURY TO THE LAMINAE | 119 | ||
NSAIDS | 119 | ||
INTRAVENOUS LIDOCAINE | 120 | ||
DISTAL LIMB CRYOTHERAPY | 120 | ||
PTX | 120 | ||
FUTURE THERAPIES | 121 | ||
REFERENCES | 121 | ||
Chapter 11. Therapeutic Hypothermia (Cryotherapy) to Prevent and Treat Acute Laminitis | 125 | ||
THE EFFECTS OF HYPOTHERMIA ON TISSUE | 126 | ||
THERAPEUTIC HYPOTHERMIA OF THE EQUINE DISTAL LIMB | 127 | ||
USING DIGITAL HYPOTHERMIA TO HELP PREVENT LAMINITIS | 128 | ||
USING DIGITAL HYPOTHERMIA FOR THE TREATMENT OF ACUTE LAMINITIS | 130 | ||
REFERENCES | 130 | ||
Chapter 12. Progression of Venographic Changes After Experimentally Induced Laminitis | 135 | ||
VENOGRAPHIC TECHNIQUE | 136 | ||
VENOGRAPHY OF CONTROL (NORMAL) FEET BEFORE OF DOSING | 136 | ||
VENOGRAPHY 48 HOURS AFTER OF DOSING | 137 | ||
VENOGRAPHY 7 DAYS AFTER OF DOSING | 138 | ||
VENOGRAPHY 6 WEEKS AFTER OF DOSING | 138 | ||
SUMMARY | 140 | ||
ACKNOWLEDGMENTS | 140 | ||
REFERENCES | 140 | ||
Chapter 13. Clinical Presentation, Diagnosis, and Prognosis of Chronic Laminitis in North America | 141 | ||
CLINICAL PRESENTATION | 141 | ||
DIAGNOSIS | 147 | ||
PROGNOSIS | 151 | ||
SUMMARY | 152 | ||
REFERENCES | 152 | ||
Chapter 14. Pathology of the Distal Phalanx in Equine Laminitis: More Than Just Skin Deep | 155 | ||
ARCHITECTURE OF THE DISTAL PHALANX | 156 | ||
BONE MICROENVIRONMENT | 159 | ||
OSTEOIMMUNOLOGY AND INFLAMMATION-INDUCED BONE MODELING | 160 | ||
BIOMECHANICALLY INDUCED BONE MODELING | 162 | ||
SUMMARY | 162 | ||
REFERENCES | 163 | ||
Chapter 15. Equine Venography and Its Clinical Application in North America | 167 | ||
PERFORMING THE VENOGRAM | 167 | ||
THE 6 AREAS OF INTEREST OF THE NORMAL VENOGRAM | 170 | ||
INTERPRETATION | 170 | ||
CLINICAL APPLICATION | 172 | ||
ACKNOWLEDGMENTS | 176 | ||
REFERENCES | 176 | ||
Chapter 16. The Lamellar Wedge | 179 | ||
OVERVIEW | 179 | ||
PATHOGENESIS OF THE LAMELLAR WEDGE | 179 | ||
TEMPORAL DEVELOPMENT OF THE LAMELLAR WEDGE | 187 | ||
HIDDEN DANGERS: PATHOLOGIC CONSEQUENCES OF DP DISLOCATION | 189 | ||
THE LAMELLAR WEDGE IN THE PASTURE-INDUCED LAMINITIC HORSE | 193 | ||
SUSCEPTIBILITY TO ONYCHOMYCOSIS | 193 | ||
SUMMARY | 193 | ||
REFERENCES | 194 | ||
Chapter 17. Chronic Laminitis: Strategic Hoof Wal l Resection | 197 | ||
PERFORMING THE WALL RESECTION | 198 | ||
AFTERCARE | 202 | ||
COMPLICATIONS | 203 | ||
COMPLETE WALL RESECTION WITH DISTAL DISPLACEMENT | 204 | ||
ACKNOWLEDGMENTS | 204 | ||
REFERENCES | 204 | ||
Chapter 18. The Use of the Wooden Shoe (Steward Clog) in Treating Laminitis | 207 | ||
REFERENCES | 214 | ||
Chapter 19. Home Care for Horses with Chronic Laminitis | 215 | ||
PAIN MANAGEMENT | 215 | ||
CONCURRENT MEDICAL ISSUES | 217 | ||
NUTRITION | 217 | ||
REHABILITATION | 219 | ||
NURSING CARE | 220 | ||
HOUSING AND FOOTING | 220 | ||
HOOF CARE | 221 | ||
ENSURING OWNER COMPLIANCE | 222 | ||
REFERENCES | 222 | ||
Index | 225 |