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SPEC - Diagnostic Atlas of Renal Pathology E-Book 12 Month Subscrition

SPEC - Diagnostic Atlas of Renal Pathology E-Book 12 Month Subscrition

Agnes B. Fogo | Michael Kashgarian

(2011)

Additional Information

Book Details

Abstract

Diagnostic Atlas of Renal Pathology, by Agnes B. Fogo, MD and Michael Kashgarian, MD, delivers practical, highly visual guidance for effectively and accurately diagnosing a wide range of pathologic entities. More than 700 high-quality illustrations help you to recognize the pathologic features and clinical manifestations of both common and rare renal disorders and to formulate confident and accurate diagnoses. Thoroughly updated throughout, this companion to Brenner & Rector’s The Kidney, 9th Edition provides the newest information regarding categorizing and classification of diseases and describes how this relates to the various morphological lesions illustrated and their clinical significance.

  • See more than 700 high quality representative images of light, immunofluorescence, and electron microscopy for each diagnostic entity with correlations to clinical presentation and pathogenesis.
  • Easily locate in-depth information on any disease's clinical course and treatment by cross-referring companion text, Brenner & Rector’s The Kidney.
  • Grasp key characteristic pathologic findings and prognostic, pathogenetic, and etiologic information through focused, detailed discussions.
  • Make accurate, complete reports by fully understanding clinical correlations.
  • Get an in-depth examination of pathophysiology, clinical presentations, and comprehensive references
  • Keep current with the latest knowledge and evidence-based practices. Comprehensive updates throughout include a brand-new chapter on "Approaches to Chronic Kidney Disease" that includes coverage of Chronic Kidney Disease; Age-Related Sclerosis; Glomerular vs. Tubulointerstitial vs. Vascular Disease; and the differential diagnostic approach to Segmental Glomerulosclerosis lesions. Extensive updates to all previous chapters include new classifications of various diseases such as igA nephropathy, diabetic nephropathy, crescentic GN, and renal transplant rejection.
  • Stay well informed about hot topics including acute phosphate nephropathy; new concepts in the pathogenesis of thrombotic microangiopathies and eclampsia; and new information relative to etiology and pathogenesis of podocytopathies.
  • Quickly access the information you need thanks to a user-friendly format, tables and sidebars with key points and differential diagnoses, and chapters that include concise, templated discussions regarding the etiology and pathogenesis of the disorder.

Table of Contents

Section Title Page Action Price
Front cover cover
Inside front cover ifc1
Diagnostic Atlas of Renal Pathology, 2/e i
Copyright ii
Preface iii
Acknowledgments v
Table of Contents vii
1 Glomerular Diseases 1
Normal Growth and Maturation 2
Selected Reading 10
Primary Glomerular Diseases 11
Glomerular Diseases That Cause Nephrotic Syndrome: Non–Immune Complex 11
Minimal Change Disease and Focal Segmental Glomerulosclerosis: Introduction 11
Minimal Change Disease 12
Selected Reading 16
Focal Segmental Glomerulosclerosis 16
Diagnosis of Recurrence of FSGS in the Transplant 24
Differential Diagnosis of MCD vs. FSGS 26
Etiology/Pathogenesis 26
Selected Reading 27
General 27
Genetics 28
Collapsing Glomerulopathy 28
Etiology/Pathogenesis 32
Selected Reading 34
Tip Lesion Variant of FSGS 35
Etiology/Pathogenesis 37
Selected Reading 37
Cellular Variant of FSGS 37
Etiology/Pathogenesis 38
Selected Reading 38
Perihilar Variant of FSGS 39
Etiology/Pathogenesis—Secondary Forms of FSGS 39
Selected Reading 41
Congenital Nephrotic Syndrome of Finnish Type 42
Etiology/Pathogenesis 42
Selected Reading 45
Diffuse Mesangial Sclerosis 45
Frasier Syndrome 45
Etiology/Pathogenesis 46
Selected Reading 50
Glomerular Diseases That Cause Nephrotic/Nephritic Syndrome: Complement Related 50
C1q Nephropathy 50
Etiology/Pathogenesis 52
Selected Reading 53
Dense Deposit Disease 53
Etiology/Pathogenesis 55
Selected Reading 60
C3 Glomerulonephritis 61
Etiology/Pathogenesis 61
Selected Reading 65
Glomerular Diseases That Cause Nephrotic Syndrome: Immune Complex 65
Membranous Nephropathy 65
Etiology/Pathogenesis 78
Selected Reading 79
Membranoproliferative Glomerulonephritis, Type I 80
Etiology/Pathogenesis 88
Selected Reading 93
Fibrillary Glomerulonephritis 94
Etiology/Pathogenesis 101
Selected Reading 101
Immunotactoid Glomerulopathy 102
Etiology/Pathogenesis 104
Selected Reading 106
Glomerular Diseases That Cause Hematuria or Nephritic Syndrome: Immune Complex 107
Acute Postinfectious Glomerulonephritis 107
Etiology/Pathogenesis 115
Selected Reading 117
IgA Nephropathy 118
Etiology/Pathogenesis 128
Selected Reading 131
Secondary Glomerular Diseases 132
Diseases Associated with Nephrotic Syndrome 132
Monoclonal Immunoglobulin Deposition Disease 132
Amyloidosis 133
Etiology/Pathogenesis 141
Light Chain Deposition Disease 142
Light and Heavy Chain Deposition Disease and Heavy Chain Deposition Disease 151
Etiology/Pathogenesis of MIDD 154
Selected Reading 158
Amyloidosis 158
LCDD, LHCDD, and HCDD 159
Proliferative Glomerulonephritis with Monoclonal Deposits 159
Etiology/Pathogenesis 162
Selected Reading 163
HIV-Associated Nephropathy 163
Etiology/Pathogenesis 166
Selected Reading 169
Sickle Cell Nephropathy 170
Etiology/Pathogenesis 175
Selected Reading 176
Fabry Disease 177
Etiology/Pathogenesis 180
Selected Reading 182
Lipoprotein Glomerulopathy 183
Selected Reading 185
Lecithin-Cholesterol Acyltransferase Deficiency 185
Etiology/Pathogenesis 188
Selected Reading 188
Hereditary Focal Segmental Glomerulosclerosis 189
Selected Reading 190
Diseases Associated with Nephritic Syndrome or RPGN: Immune Mediated 190
Lupus Nephritis 190
Histopathology 194
Class I Minimal Mesangial Lupus Nephritis 194
Class II Mesangial Proliferative Lupus Nephritis 195
Class III Focal Lupus Nephritis 195
Class IV Diffuse Lupus Nephritis 198
Class V Membranous Lupus Nephritis 202
Class VI Advanced Sclerosing Lupus Nephritis 203
Atypical Presentations of Renal Involvement in SLE 212
Lupus Podocytopathy/Minimal Change Disease 212
ANCA-Associated Nephritis 214
Mixed Patterns and Transformation 214
Immunofluorescence Microscopic Features 215
Additional Pathologic Features 218
Vascular Lesions 218
Tubulointerstitial Disease 220
Assessment of Severity and Chronicity 221
Etiology/Pathogenesis 222
Selected Reading 223
Henoch–Schönlein Purpura 223
Etiology/Pathogenesis 232
Selected Reading 232
Mixed Connective Tissue Disease 233
Etiology/Pathogenesis 233
Selected Reading 241
Mixed Cryoglobulinemia 241
Etiology/Pathogenesis 249
Selected Reading 252
Anti-GBM Antibody–Mediated Glomerulonephritis 252
Etiology/Pathogenesis 256
Selected Reading 260
Diseases Associated with the Nephritic Syndrome or RPGN: Pauci-Immune- or Non-Immune-Mediated 260
Introduction 260
Granulomatosis with Polyangiitis (Wegener)/Microscopic Polyangiitis 262
Etiology/Pathogenesis 267
Selected Reading 271
Polyarteritis Nodosa 271
2 Vascular Diseases 303
Diabetic Nephropathy 303
Etiology/Pathogenesis 314
Selected Reading 315
Thrombotic Microangiopathy/Thrombotic Thrombocytopenic Purpura 315
Etiology/Pathogenesis 328
Selected Reading 329
Scleroderma (Progressive Systemic Sclerosis) 330
Etiology/Pathogenesis 336
Selected Reading 337
Antiphospholipid Antibody Disease 338
Etiology/Pathogenesis 338
Selected Reading 338
Preeclampsia and Eclampsia 338
Pathology 339
Etiology/Pathogenesis 339
Selected Reading 348
Fibromuscular Dysplasia 348
Etiology/Pathogenesis 349
Pathology 349
Selected Reading 353
Arterionephrosclerosis 353
Etiology/Pathogenesis 361
Selected Reading 363
Accelerated/Malignant Hypertension 364
Etiology/Pathogenesis 368
Selected Reading 369
Atheroemboli 369
Etiology/Pathogenesis 373
Selected Reading 374
3 Tubulointerstitial Diseases 377
Introduction 377
Acute Pyelonephritis 379
Etiology/Pathogenesis 380
Selected Reading 385
Chronic Pyelonephritis and Reflux Nephropathy 385
4 Chronic Kidney Disease 465
Introduction 465
Age-Related Sclerosis 465
Selected Reading 468
Glomerular vs. Tubulointerstitial vs. Vascular Disease 469
Selected Reading 469
Segmental Glomerulosclerosis: Primary vs. Secondary 470
Selected Reading 471
5 Renal Transplantation 473
Introduction 473
Etiology/Pathogenesis 475
Antibody-Mediated Rejection 475
Chronic Active Antibody-Mediated Rejection and Transplant Glomerulopathy 478
Acute T Cell–Mediated Rejection 479
Borderline Changes: “Suspicious for Acute Rejection” 480
Banff Type I Acute Rejection 480
Banff Type II Acute Rejection 482
Banff Type III Acute Rejection 483
Chronic Allograft Failure (Chronic Allograft Nephropathy) 485
Cyclosporin/FK506 Nephrotoxicity 486
Etiology/Pathogenesis 488
Posttransplant Lymphoproliferative Disease 488
Etiology/pathogenesis 491
Selected Reading 491
Viral Infections 491
Selected Reading 497
6 Cystic Diseases of the Kidney 499
Introduction 499
Autosomal Dominant Polycystic Kidney Disease 499
Pathology 499
Autosomal Recessive Polycystic Kidney Disease 504
Pathology 505
Medullary Cystic Disease/Nephronophthisis 506
Medullary Sponge Kidney 508
Etiology/Pathogenesis 510
Selected Reading 511
Acquired Cystic Disease 511
Selected Reading 513
Cystic Renal Dysplasia 513
Etiology/Pathogenesis 516
Selected Reading 516
7 Renal Neoplasia 517
Introduction 517
Renal Cell Carcinomas 517
Other Renal Epithelial Tumors 519
Etiology/Pathogenesis 519
Selected Reading 529
Wilms Tumor 529
Etiology/Pathogenesis 532
Selected Reading 533
Transitional Cell Carcinoma of the Renal Pelvis 533
Etiology/Pathogenesis 534
Selected Reading 534
Index 535
A 535
B 536
C 536
D 538
E 538
F 538
G 539
H 540
I 541
J 542
K 542
L 543
M 543
N 545
O 545
P 545
R 547
S 548
T 549
U 550
V 550
W 550
X 550