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Primary Care - E-Book

Primary Care - E-Book

Terry Mahan Buttaro | JoAnn Trybulski | Patricia Polgar-Bailey | Joanne Sandberg-Cook

(2012)

Additional Information

Book Details

Abstract

Written by and for Nurse Practitioners from a unique collaborative perspective, Primary Care: A Collaborative Practice, 4th Edition, prepares you to provide care for all of the major disorders of adults seen in the outpatient setting. Evidence-based content reflects the latest guidelines for primary care of hundreds of conditions, including hypertension, diabetes, and sexually transmitted infections. Now in full color, the 4th Edition includes chapters on emerging topics such as genetics, obesity, lifestyle management, and emergency preparedness. Combining a special blend of academic and clinical expertise, the author team provides a practical text/reference that promotes a truly collaborative primary care practice.

  • Comprehensive, evidence-based content incorporates the latest standardized guidelines for primary care in today's fast-paced, collaborative environment.
  • Unique! A collaborative perspective, reflecting the key roles of NPs, MDs, PAs, PharmDs, and others, promotes seamless continuity of care.
  • A consistent format from chapter to chapters facilitates learning and clinical reference value.
  • Diagnostics and Differential Diagnosis boxes provide a quick reference for diagnosing disorders and helping to develop effective management plans.
  • Physician Consultation icons highlight situations or conditions in which consultation is either recommended or necessary.
  • Emergency Referral icons identify signs and symptoms that indicate the need for immediate referral to an emergency facility.
  • Co-management with Specialists discussions help you provide truly collaborative care in the outpatient setting.
  • Complementary and alternative therapies are addressed where supported by solid research evidence.

Table of Contents

Section Title Page Action Price
Front Cover Cover
Primary care: A Collaborative Practice i
Copyright ii
Dedication iii
Contributors v
Reviewers xx
Preface xxi
Format xxi
Emergency and physician referral icons xxi
Diagnostics and differential diagnosis boxes xxi
Management xxii
Acknowledgments xxii
Contents xxiii
Part 1: Introduction 1
Chapter 1: The Changing Landscape of Collaborative Practice 1
Current forces shaping the primary care landscape 1
Decreasing Numbers of Physician Primary Health Care Providers and Solutions 1
New Providers, New Roles: DNP and Nurse as Health Coach 1
Established Providers, New Roles: DPT, PharmD, Hospitalist, Intensivist, and Perioperativist 1
New Venues for Primary Care: Retail Health Clinics 2
The future landscape 2
Health Care Reform 2
Technology in Primary Care: Telemedicine and Electronic Medical Records 2
Patient-Centered Medical Home 2
Accountable Care Organizations 2
The continued value of collaborative practice 3
Building collaborative practice 3
Elements of collaborative practice 3
Recognition of Patient Needs 3
Trust 3
Recognition of Each Discipline's Contribution 4
Time 4
Challenges inherent in collaborative practice 4
Conclusion 4
References 4
Chapter 2: Translating Research into Clinical Practice 5
Research designs and data analysis methods 5
Level I Research: Descriptive Studies 5
Level II Research: Relationships Between or Among Variables 5
Research Methods for Level II Questions 5
Level III Research: Cause and Effect 5
Experimental Design 5
Quasi-Experimental Design 6
Level IV Research: Randomized Clinical Trials 7
Random Selection and Random Assignment 7
Placebos 7
Blinding of the Subject and Researcher 7
Weighing the evidence: evaluating key study parameters 8
Type I and Type II Errors 8
Power Analysis 8
Description of Data and Measures of Central Tendency 9
Standard Deviation 9
Distribution and Error 9
Statistical Significance (Alpha Values) 9
Statistics of Differences and Associations 9
Clinical Significance Versus Statistical Significance 10
Crossing the divide: translating research results into clinical practice 10
What is Translational Research? 10
Thornicroft's Translational Medicine Continuum 10
Strategies to form and to accelerate research collaborations 11
Forming Research Partnerships Between Clinicians and Researchers 11
Initiating Collaborations 11
Merging Perspectives 12
Accelerating Research Collaborations: The National Institutes of Health Roadmap 12
Clinical Research Networks and National Electronics Clinical Trials and Research Program 12
Clinical Outcomes Assessment 12
Clinical Research Training 12
Clinical Research Policy Analysis and Coordination 12
Translational Research 12
Understanding the research process 13
Developing the Research Question, Proposal, and Research Protocol 13
Role of the Team Leader 13
Resource Issues 13
Enhancing the Research Infrastructure: Interdisciplinary Team Building 13
Challenges of Research Collaboration on Career Development 14
Collaborative Research as a Strategy for Career Development 14
Benefits of Having a Mentor 14
Summary 14
References 14
Chapter 3: The Patient, the Provider, and Primary Care: An Integrated Perspective 15
Functional medicine 16
The patient encounter 16
Cross-culturalism and health literacy 16
References 17
Chapter 4: Professional Integrity and Decision-Making in Primary Care 17
Ethical issues 18
Essential ethical principles 18
Contemporary theoretical perspectives in ethics 18
Language of ethics 18
Ethical dilemmas 18
Analysis of Ethical Dilemmas 19
Patient and Provider Perspectives 19
Research in nursing ethics 19
Creating a primary care practice environment that fosters ethical decisions and promotes professional integrity 20
Summary 20
References 20
Chapter 5: Population-Based Care for Primary Care Providers 21
Chronic care model 21
Organizational Support 21
Clinical Information Systems 21
Delivery System Design 22
Decision Support 22
Self-Management Support 22
Community Resources 23
The patient-centered medical home 23
Population management 23
Population Health 24
Population Disease Management 24
Case/Care Management 24
Preparing for the primary care practice of the future 25
Clinical Information Systems 25
Leading Teams 25
Self-Management Support and Delivery System Design 26
Techniques to Encourage Patient Self-Management: The Transtheoretical Model and Motivational Interviewing 26
Summary 27
References 29
Chapter 6: Reimbursement for Nurse Practitioner Services 29
Third-party payers: critical partners 30
Medicare 30
Medicaid 30
Commercial Indemnity Insurers 30
Managed Care Organizations 30
Direct Contracts for Health Care 31
Regulations surrounding nurse practitioner reimbursement 31
General Information 31
Types of Nurse Practitioner Services That May Be Covered 31
Nurse Practitioner Services Not Covered 31
Collaboration 31
Incident to\" Billing 31
Nursing Facilities 31
Hospital Visits and Procedures 31
Hospice 32
Home Visits 32
How to apply for provider status 32
Medicare 32
Medicaid 32
Managed Care Organizations 32
Commercial Indemnity Insurers 32
Billing of third-party payers 33
Coding 33
Documentation 33
Health care reform: what will it mean for nurse practitioners? 33
Resources 33
References 33
Chapter 7: Health Literacy, Health Care Disparities, and Culturally Responsive Primary Care 34
Health care literacy 34
Identification and management of inadequate health literacy 34
REALM and TOFHLA 34
Health Care Literacy and Oral Communication Skills 34
Effect of Reading Comprehension on Health Care Literacy 34
Ask Me 3 35
Strategies to Increase Health Care Literacy 35
Health outcomes and health literacy 35
Health care disparities 35
A Powerful Example: Disparities in Diabetes Care 36
Glycemic Control 36
Diabetes Complications 36
Amputations 36
End-Stage Renal Disease 36
Challenges in Understanding Diabetes Disparities 36
A Population at Risk for Health Care Disparities: Lesbian, Gay, Bisexual, and Transgender Patients 37
Transgendered or Transsexual Patients 37
Sexual Reassignment 37
Creating a Care Environment for LGBT Patients 37
Guidelines for delivery of culturally responsive care 38
Components of Culturally Responsive Primary Care 38
Address Cultural Variations Among Diverse Patient Groups 38
Create a Patient-Centered Friendly Environment 38
Minimize Clinician Bias 38
Overcome Patient Language Barriers 39
Conclusion 39
References 39
Chapter 8: Genetic Considerations in Primary Care 40
Risk assessment 40
Family history 41
Gathering a Family History 42
Interpreting a Family History 42
Common inheritance patterns 46
Autosomal Dominant 46
Autosomal Recessive 46
X-Linked Disorders 46
Genetic information nondiscrimination act (GINA) 46
Direct-to-consumer genetic testing 46
Summary 47
References 48
Part 2: Primary Care: Adolescence Through Adulthood 49
Chapter 9: Adolescent Issues 49
Physical development 49
Cognitive development 50
Emotional development 50
Social development 50
Developmental history 50
The adolescent health visit 51
References 53
Chapter 10: Pregnancy and Prenatal Care 54
Goals of prenatal care 54
Barriers to prenatal care 54
Delivery of prenatal care 54
Content of prenatal visit 55
Diagnosis of Pregnancy 55
Estimated Date of Confinement 55
Gravidity and Parity 55
Health History 55
Nutrition and Weight Gain in Pregnancy 55
Activity in Pregnancy 57
Physical Examination and Laboratory and Diagnostic Tests 57
Counseling and Education 58
Common problems in pregnancy 58
Infections 58
Urinary Tract Infections 58
Vaginitis 58
Nausea and Vomiting 59
Gastroesophageal Reflux 59
Constipation 59
Obstetric complications 60
Bleeding in Pregnancy 60
Preterm Labor 60
Other medical conditions in pregnancy 60
Asthma 61
Hypertension 61
Diabetes 62
Thyroid Disease 63
Gallbladder Disease 63
Integrated health care for women 64
References 64
Chapter 11: Lactation Guidance 65
The first few days 66
Discharge instructions 66
Neonatal jaundice 67
True Breast Milk Jaundice 67
Managing challenges to breastfeeding success 67
Attachment and Latch-on in Newborns 67
Breast Engorgement 68
Let-Down 68
Low Milk Production 68
Low Infant Weight Gain 69
Cracked Nipples 69
Mastitis 69
Referrals 69
Other considerations 69
Working Mothers 69
Multiple Births 69
Breast Pumps 70
Weaning 70
Summary 70
References 70
Chapter 12: Aging and Common Geriatric Syndromes 71
Challenges in primary care 71
Mental status and functional assessments 71
Issues with health screening 71
Counseling elderly drivers 72
Importance of advance directives 72
Common geriatric syndromes 72
Polypharmacy 72
Definition and Etiology 72
Pathophysiology 72
Part 3: Health Maintenance 105
Chapter 17: Obesity and Weight Management 105
Epidemiology 105
Definition 105
Body Mass Index 105
Bioimpedance Analysis 105
Anthropometric Measures 105
Pathophysiology 106
Energy Output 107
Insufficient Physical Activity 107
Energy Intake 107
Genetics 107
Maternal Influences 108
Smoking Cessation 108
Pharmaceuticals 108
Neuroleptic and Seizure Medications 108
Antihistamines 108
Hormonal Preparations 108
Cardiac Medications 108
Diabetes Medications 109
Environmental Factors 109
Sleep Factors 109
Gut Microbiota 109
Psychosocial Stress 109
Food Quality, Nutrients, and Availability 109
Complications, Social Stigma, and Discrimination 110
Increased Morbidity and Mortality 110
Clinical presentation 110
Physical examination 111
Diagnostics 111
Differential diagnosis 111
Management 111
Reducing Energy Intake 111
Proteins 111
Carbohydrates 112
Fats 113
Alcohol 113
Weight Loss Diets 113
Look AHEAD 113
Side Effects of Weight Loss 114
Resources for Weight Loss 114
Pharmacotherapy 114
Dietary Supplements 115
Bariatric Surgery 115
Indications and Contraindications 115
Surgical Techniques and Outcomes 115
Surgical Complications 116
Nutritional Supplementation 116
Monitoring 116
Medications 116
Pregnancy 116
Weight Gain 116
Psychological Results 116
Preoperative Management 116
Motivational Interviewing in Weight Management 117
Life span considerations 117
Indications for referral or hospitalization 117
Education and health promotion 117
References 118
Obesity 120
Sedentary Lifestyle 120
Part 4: Office Emergencies 184
Chapter 25: Emergency Preparedness, Recognition, and Response in Primary Care 184
The evolution of emergency preparedness and the need to prepare 184
Emergency management 184
Incident command system overview 185
Planning the role of primary care in disaster situations 186
Primary care and surge capacity 186
H1N1: Primary Care During a Pandemic Influenza Event 187
Hurricane Katrina: Primary Care During the Post-Disaster Period 187
Summary 188
References 188
Chapter 26: Acute Bronchospasm 189
Definition and epidemiology 189
Pathophysiology 189
Clinical presentation 189
Physical examination 189
Diagnostics 189
Differential diagnosis 189
Initial stabilization and management 190
Disposition and referral 190
Prevention and patient education 190
References 191
Chapter 27: Anaphylaxis 191
Differential diagnosis 192
Management 192
Complications 193
Indications for referral or hospitalization 193
Life span considerations 193
Education and health promotion 193
References 193
Chapter 28: Bites and Stings 194
Insect Bites and Stings 194
Definition And Epidemiology 194
Pathophysiology And Clinical Presentation 194
Physical Examination 194
Diagnostics 194
Differential Diagnosis 194
Initial Stabilization And Management 194
Disposition And Referral 195
Prevention And Patient Education 195
Spider Bites 195
Definition And Epidemiology 195
Pathophysiology And Clinical Presentation 196
History And Physical Examination 196
Diagnostics 196
Differential Diagnosis 196
Initial Stabilization And Management 196
Disposition And Referral 197
Prevention And Patient Education 197
Reptile Bites and Scorpion Stings 197
Definition And Epidemiology 197
Pathophysiology 197
Clinical Presentation 197
Physical Examination 197
Diagnostics 197
Differential Diagnosis 198
Initial Stabilization And Management 198
Disposition And Referral 198
Prevention And Patient Education 198
References 198
Chapter 29: Bradycardia and Tachycardia 198
Pathophysiology 199
Clinical presentation 199
Physical examination 199
Diagnostics 199
Differential diagnosis 199
Initial stabilization and management 199
Disposition and referral 200
Prevention 200
Patient and family education 200
Tachycardia 200
Definition and epidemiology 200
Pathophysiology 200
Clinical presentation 200
Physical examination 200
Diagnostics 200
Differential diagnosis 201
Initial stabilization and management 201
Disposition and referral 202
Prevention and patient education 202
References 202
Chapter 30: Cardiac Arrest 202
Pathophysiology 203
Clinical presentation 203
Physical examination 203
Diagnostics 204
Differential diagnosis 204
Initial stabilization and management 204
Complications 204
Disposition and referral 204
Prevention 204
Patient and family education 205
References 205
Chapter 31: Chemical Exposure 205
Physical examination 206
Diagnostics and differential diagnosis 206
Initial stabilization and management 206
Ingestions 207
Skin Exposure 207
Disposition and referral 207
Prevention and patient education 207
Resources 207
References 207
Chapter 32: Electrical Injuries 208
Physical examination 209
Diagnostics 209
Differential diagnosis 209
Initial stabilization and management 209
Disposition and referral 209
Prevention and patient and family education 209
References 210
Chapter 33: Head Trauma 210
Physical examination 211
Diagnostics 211
Differential diagnosis 211
Initial stabilization and management 212
Disposition and referral 212
Patient and family education 212
References 212
Chapter 34: Hypotension 212
Pathophysiology 213
Clinical presentation 213
Physical examination 213
Diagnostics 213
Differential diagnosis 214
Initial stabilization and management 214
Disposition and referral 214
Prevention and patient education 214
References 214
Chapter 35: Poisoning 215
Definition 215
Epidemiology 215
Pathophysiology 215
Clinical presentation 215
Physical examination 215
Diagnostics 215
Differential diagnosis 216
Initial stabilization and management 216
Terrorism 216
Prevention and patient education 217
References 217
Chapter 36: Sexual Assault 217
Initial stabilization and management and physical examination 218
Primary Care Management 218
Physical Examination 219
Documentation 219
Life span considerations 219
Adolescents 219
Older Adults 219
Specific populations 219
Male Patients 219
Immigrants 219
Disposition and referral 220
Prevention and patient education 220
References 220
Chapter 37: Syncope 220
Clinical presentation 221
Physical examination 222
Diagnostics 222
Differential diagnosis 222
Initial stabilization and management 222
Disposition and referral 222
Prevention and patient education 223
References 223
Chapter 38: Thermal Injuries 223
Physical examination 224
Diagnostics 224
Differential diagnosis 224
Management 224
Complications 225
Indications for referral or hospitalization 225
Patient education and health promotion 225
Cold Injury 225
Definition and epidemiology 225
Pathophysiology 225
Clinical presentation 225
Physical examination 225
Diagnostics 226
Differential diagnosis 226
Management (including co-management with specialists) 226
Complications 226
Indications for referral or hospitalization 226
Life span considerations 226
Education and health promotion 226
References 226
Part 5: Evaluation and Management of Skin Disorders 227
Chapter 39: Examination of the Skin and Approach to Diagnosis of Skin disorders 227
Definition and epidemiology 227
Overview of skin function, anatomy, and structures 227
Changes in the skin associated with aging 227
Assessment 227
History 229
Physical Examination 229
References 230
Chapter 40: Surgical Office Procedures 230
Electrocautery 231
Curettage 231
Biopsy 231
Summary 232
References 233
Chapter 41: Principles of Dermatologic Therapy 233
Topical Corticosteroids 235
Patient and family education 235
References 235
Chapter 42: Screening for Skin Cancer 235
Pathophysiology 236
Clinical presentation 236
Physical examination 236
Diagnostics 237
Differential Diagnosis 237
Management 237
Treatment 237
Co-Management with Specialists 237
Complications and life span considerations 238
Indications for referral or hospitalization 238
Patient education and health promotion 238
References 238
Chapter 43: Acne Vulgaris 238
Pathophysiology 239
Clinical presentation and physical examination 239
Diagnostics and differential diagnosis 240
Management 240
Rosacea 241
Complications 241
Indications for referral or hospitalization 241
Patient and family education 241
Health promotion 241
References 242
Chapter 44: Alopecia 242
Physical examination 243
Diagnostics 243
Differential diagnosis 243
Management 244
Complications 244
Indications for referral or hospitalization 244
Patient and family education 244
References 244
Chapter 45: Animal and Human Bites 245
Definition and epidemiology 245
Pathophysiology 245
Clinical presentation 245
Physical examination 246
Diagnostics 246
Management 246
Complications 246
Indications for referral or hospitalization 247
Patient education and health promotion 247
References 247
Chapter 46: Burns (Minor) 247
Clinical presentation 248
Physical examination 248
Diagnostics 248
Differential diagnosis 248
Management 248
Complications 249
Indications for referral or hospitalization 249
Patient and family education 249
Health promotion 249
References 249
Chapter 47: Cellulitis 249
Pathophysiology 250
Clinical presentation and physical examination 250
Diagnostics 250
Differential diagnosis 250
Management 251
Complications and indications for referral or hospitalization 251
Patient and family education 251
References 251
Chapter 48: Contact Dermatitis 252
Definition and epidemiology 252
Clinical presentation and physical examination 252
Diagnostics and differential diagnosis 252
Management 253
Complications 253
Indications for referral or hospitalization 253
Patient and family education 253
References 253
Chapter 49: Corns and Calluses 254
Definition 254
Pathophysiology 254
Clinical presentation 254
Physical examination 254
Diagnostics and differential diagnosis 254
Management 254
Co-Management with Specialists 255
Life span considerations 255
Complications 255
Indications for referral or hospitalization 255
Patient education and health promotion 255
References 255
Chapter 50: Cutaneous Herpes 256
Definition and epidemiology 256
Pathophysiology 256
Clinical presentation 256
Physical examination 256
Diagnostics 256
Differential diagnosis 257
Management 257
Primary Herpes Labialis 257
Recurrent Herpes Labialis 257
Primary Genital Herpes 258
Recurrent Genital Herpes 258
Suppression of Frequent Recurrences 258
Life span considerations 258
Complications 258
Indications for referral or hospitalization 258
Patient and family education 258
Health promotion 258
References 258
Chapter 51: Dermatitis Medicamentosa 259
Definition and epidemiology 259
Pathophysiology 259
Clinical presentation 259
Physical examination 260
Diagnostics 260
Differential diagnosis 260
Management 260
Complications 261
Indications for referral or hospitalization 261
Clinical information resources 261
Patient and family education and health promotion 261
References 261
Chapter 52 Dry Skin 261
Definition and epidemiology 261
Pathophysiology 261
Clinical presentation and physical examination 262
Diagnostics and differential diagnosis 262
Management 262
Complications 262
Indications for referral or hospitalization 262
Patient education and health promotion 263
References 263
Chapter 53: Eczematous Dermatitis (Atopic Dermatitis) 263
Management 264
Complications 264
Indications for referral or hospitalization 264
Patient and family education 265
References 265
Chapter 54: Fungal Infections (Superficial) 265
Diagnostics 266
Differential diagnosis 266
Management 266
Oral Medications 267
Complications 267
Part 6: Evaluation and Management of Eye Disorders 313
Chapter 70: Evaluation of the Eyes 313
Screening recommendations 313
History 313
Physical examination 313
Visual Acuity 314
Pupil Response 314
Intraocular Pressure 314
Ocular Alignment and Extraocular Movements 315
Visual Fields 315
External Structures 315
Anterior Segment 316
Posterior Segment 317
Signs and symptoms of ocular disease 318
Red Eye 318
Vision Loss and Other Visual Disturbances 318
Ocular and Periocular Pain 318
Other Ocular Signs and Symptoms 321
References 321
Chapter 71: Cataracts 322
Definition and epidemiology 322
Pathophysiology 322
Clinical presentation 322
Physical examination 322
Diagnostics 322
Differential diagnosis 322
Management 323
Life span considerations 323
Complications 323
Indications for referral or hospitalization 323
Patient and family education 323
Health promotion 323
References 323
Chapter 72: Blepharitis, Hordeolum, and Chalazion 324
Definition and epidemiology 324
Pathophysiology 324
Clinical presentation 324
Physical examination 324
Diagnostics 325
Differential diagnosis 325
Management 325
Life span considerations 325
Complications 325
Indications for referral or hospitalization 326
Patient and family education 326
Health promotion 326
References 326
Chapter 73: Conjunctivitis 327
Definition and epidemiology 327
Pathophysiology 327
Clinical presentation and physical examination 327
Viral Conjunctivitis 327
Bacterial Conjunctivitis 328
Acute Allergic Conjunctivitis 328
Vernal and Atopic Conjunctivitis 328
Medication Toxicity 328
Diagnostics 328
Management 328
Viral Conjunctivitis 328
Bacterial Conjunctivitis 329
Acute Allergic Conjunctivitis 329
Vernal and Atopic Conjunctivitis 329
Medication Toxicity 329
Differential diagnosis 329
Indications for referral 329
Education and health promotion 330
References 330
Chapter 74: Corneal Surface Defects and Ocular Surface Foreign Bodies 330
Pathophysiology 330
Clinical presentation 331
Physical examination 331
Diagnostics 331
Differential diagnosis 331
Management 331
Complications 332
Indications for referral 332
Prevention 332
References 332
Chapter 75: Dry Eye Syndrome 333
Definition and epidemiology 333
Pathophysiology 333
Clinical presentation 333
Physical examination 334
Diagnostics 334
Differential diagnosis 334
Management 334
Life span considerations 335
Complications 335
Indications for referral or hospitalization 335
Patient and family education 335
Health promotion 335
References 335
Chapter 76: Nasolacrimal Duct Obstruction and Dacryocystitis 335
Definition and epidemiology 335
Pathophysiology 335
Clinical presentation 335
Physical examination 336
Diagnostics 336
Differential diagnosis 336
Management 336
Complications 337
Indications for referral or hospitalization 337
Patient and family education 337
References 337
Chapter 77: Preseptal and Orbital Cellulitis 337
Physical examination 338
Diagnostics 338
Differential diagnosis 338
Management 338
Complications 338
Indications for referral or hospitalization 339
Patient and family education 339
Health promotion 339
References 339
Chapter 78: Pinguecula and Pterygium 339
Definition and epidemiology 339
Pathophysiology 339
Clinical presentation 339
Physical examination 339
Diagnostics 340
Differential diagnosis 340
Management 340
Indications for referral 340
Patient education and health promotion 340
References 341
Chapter 79: Traumatic Ocular Disorders 341
Epidemiology 341
Pathophysiology 342
Mechanical Injuries 342
Chemical Injuries 342
Clinical presentation 343
Physical examination 343
Diagnostics 343
Differential diagnosis 343
Management and indications for referral 344
Complications 344
Life span considerations 344
Education and health promotion 344
References 344
Part 7: Evaluation and Management of Ear Disorders 345
Chapter 80: Auricular Disorders 345
Definition and epidemiology 345
Pathophysiology 345
Clinical presentation 345
Physical examination 345
Diagnostics 346
Differential diagnosis 346
Management 346
Life span considerations 346
Complications 346
Indications for referral or hospitalization 346
Patient and family education 346
Health promotion 346
References 346
Chapter 81: Cerumen Impaction 347
Life span considerations 348
Complications 348
Indications for referral or hospitalization 348
Patient and family education 348
Part 8: Evaluation and Management of Nose Disorders 365
Chapter 88: Chronic Nasal Congestion and Discharge 365
Definition and epidemiology 365
Pathophysiology 365
Clinical presentation 365
Physical examination 365
Diagnostics 365
Differential diagnosis 365
Rhinitis and Rhinosinusitis 365
Medications and Street Drugs 365
Part 9: Evaluation and Management of Oropharynx Disorders 385
Chapter 95: Dental Abscess 385
Definition and epidemiology 385
Pathophysiology 385
Clinical presentation 385
Physical examination 385
Diagnostics 385
Differential diagnosis 385
Management 385
Complications 386
Indications for referral or hospitalization 386
Patient and family education and health promotion 386
References 386
Chapter 96: Diseases of the Salivary Glands 386
Clinical presentation 387
Physical examination 387
Diagnostics 387
Differential diagnosis 388
Management 388
Life span considerations 389
Complications 389
Indications for referral or hospitalization 389
Patient and family education 389
Health promotion 389
References 389
Chapter 97: Epiglottitis 389
Pathophysiology 390
Clinical presentation 390
Physical examination 390
Diagnostics 390
Differential Diagnosis 390
Management 391
Life span considerations 391
Complications 391
Indications for referral or hospitalization 391
Patient and family education 391
Health promotion 391
References 391
Chapter 98: Oral Infections 392
Definition and epidemiology 392
Pathophysiology 392
Clinical presentation 392
Physical examination 393
Diagnostics 393
Differential diagnosis 394
Management 394
Complications 395
Indications for referral or hospitalization 395
Patient education and health promotion 395
References 395
Chapter 99: Parotitis 396
Definition and epidemiology 396
Pathophysiology 396
Clinical presentation 396
Physical examination 396
Diagnostics 396
Differential diagnosis 396
Management 396
Complications 397
Indications for referral or hospitalization 397
Patient and family education and health promotion 397
References 397
Chapter 100: Peritonsillar Abscess 397
Definition and epidemiology 397
Pathophysiology 397
Clinical presentation 398
Physical examination 398
Diagnostics 398
Differential diagnosis 398
Management 398
Life span considerations 399
Complications 399
Indications for referral or hospitalization 399
Patient and family education 399
Health promotion 399
References 399
Chapter 101: Pharyngitis and Tonsillitis 399
Pathophysiology 400
Clinical presentation 400
Physical examination 400
Diagnostics 400
Differential diagnosis 401
Management 402
Life span considerations 402
Complications 402
Indications for referral or hospitalization 402
Patient and family education 402
Health promotion 403
References 403
Part 10: Evaluation and Management of Pulmonary Disorders 404
Chapter 102: Acute Bronchitis 404
Definition and epidemiology 404
Pathophysiology 404
Clinical presentation and physical examination 404
Diagnostics 404
Differential diagnosis 405
Management 405
Complications 407
Indications for referral or hospitalization 407
Patient and family education 407
References 407
Chapter 103: Asthma 407
Definition and epidemiology 407
Pathophysiology 408
Clinical presentation 409
Physical examination 411
Diagnostics 414
Differential diagnosis 415
Management 416
Medications 417
Long-Term Control Medications 417
Corticosteroids. 417
Cromolyn and Nedocromil. 424
Xanthine Derivatives. 424
Leukotriene Modifiers. 424
Immunomodulators. 428
Long-Acting Beta 2 -Adrenergic Agonists (LABAs). 428
Quick-Relief Medications 428
Short-Acting Beta 2 -Adrenergic Agonists (SABAs). 428
Anticholinergic Agents. 428
Monitoring Therapy and Asthma Severity. 428
Co-Management with Specialists. 429
Life span considerations 429
Complications 430
Indications for referral or hospitalization 430
Patient education 430
References 433
Chapter 104: Chest Pain (Noncardiac) 433
Pathophysiology 434
Clinical presentation 434
Physical examination 434
Diagnostics 435
Differential diagnosis 435
Management 436
Life span considerations 437
Complications 438
Indications for referral or hospitalization 438
Patient and family education and health promotion 438
References 438
Chapter 105: Chronic Cough 439
Definition and epidemiology 439
Pathophysiology 439
Clinical presentation 440
Physical examination 440
Diagnostics 440
Differential diagnosis 440
Management 443
Complications 444
Indications for referral or hospitalization 444
Patient and family education 444
References 445
Chapter 106: Chronic Obstructive Pulmonary Disease 445
Pathophysiology 446
Clinical presentation 446
Physical examination 446
Diagnostics 447
Differential diagnosis 447
Management 448
Pharmacotherapy 449
Bronchodilators. 451
Anticholinergic Therapy 451
Beta 2 -Adrenergic Agonist Therapy 451
Combination Therapy 451
Methylxanthine Therapy 451
Corticosteroids 451
Combination Inhaled Glucocorticosteroid and BronchŁodilator Therapy 452
Phosphodiesterase-4 Inhibitors 452
Mucoactive Agents 452
Antibiotics 452
Pulmonary Rehabilitation 452
Exercise Training 452
Immunizations 452
Psychological Support 452
Nutrition 452
Surgery 453
Complications 453
Indications for referral or hospitalization 454
Patient and family education 454
References 454
Chapter 107: Dyspnea 454
Pathophysiology 455
Clinical presentation 455
Quality 455
Timing 455
Intensity 455
Associated Symptoms 455
Exposures 455
Physical examination 456
Diagnostics 456
Differential diagnosis 457
Management 457
Complications 458
Indications for referral or hospitalization 458
Patient and family education and health promotion 458
References 458
Chapter 108: Hemoptysis 458
Pathophysiology 459
Clinical presentation 459
Physical examination 459
Diagnostics 460
Differential diagnosis 460
Management 461
Complications 461
Indications for referral or hospitalization 461
Patient and family education 461
References 461
Chapter 109: Lung Cancer 461
Pathophysiology 462
Clinical presentation 462
Physical examination 462
Diagnostics 463
Differential diagnosis 463
Management 465
Surgery in Non–Small Cell Lung Cancer 465
Radiotherapy 465
Chemotherapy 465
Targeted Therapies 466
Complications 466
Indications for referral or hospitalization 466
Patient and family education 466
Health promotion 466
References 466
Chapter 110: Pleural Effusions and Pleurisy 467
Clinical presentation 468
Physical examination 468
Diagnostics 468
Differential diagnosis 469
Management 470
Complications 470
Indications for referral or hospitalization 470
Patient and family education 470
Pleurisy 470
Definition and epidemiology 470
Pathophysiology 470
Clinical presentation 470
Physical examination 470
Diagnostics 471
Differential diagnosis 471
Management 471
Complications 471
Indications for referral or hospitalization 471
Patient and family education 472
References 472
Chapter 111: Pneumonia 472
Definition and epidemiology 472
Pathophysiology 473
Clinical presentation and physical examination 474
Bacterial Pneumonia Syndromes 474
Gram-Positive Bacteria. 474
Gram-Negative Bacteria. 474
Atypical Pneumonia Syndromes 474
Diagnostics 475
Chest Radiography 475
Sputum Analysis 475
Other Tests 475
Differential diagnosis 476
Management 476
Complications 477
Indications for referral or hospitalization 477
Patient and family education 477
Health promotion 477
References 477
Chapter 112: Pneumothorax 478
Definition and epidemiology 478
Pathophysiology 478
Clinical presentation 478
Physical examination 478
Diagnostics 478
Diagnosis 479
Management 479
Life span considerations 479
Complications 479
Indications for referral or hospitalization 479
Patient and family education 479
References 480
Chapter 113: Pulmonary Hypertension 480
Clinical presentation 481
Physical examination 481
Diagnostics 481
Differential diagnosis 482
Management 482
Complications 483
Indications for referral or hospitalization 483
Patient and family education 483
Health promotion 483
References 483
Chapter 114: Sarcoidosis 483
Pathophysiology 484
Clinical presentation and physical examination 484
Diagnostics 484
Differential diagnosis 485
Management 485
Life span considerations 486
Complications 486
Indications for referral or hospitalization 486
Patient and family education 486
References 486
Part 11: Evaluation and Management of Cardiovascular Disorders 487
Chapter 115: Cardiac Diagnostic Testing: Noninvasive Assessment of Coronary Artery Disease 487
Pathophysiology of coronary artery disease 487
Role of Inflammation and Atherogenesis 487
Relation to Cardiac Stress Testing 487
Overview of cardiac diagnostic testing 487
Noninvasive Tests and Biomarkers for Coronary Artery Disease 487
Exercise Tolerance Test 488
Imaging Adjuncts to the Exercise Tolerance Test 489
Myocardial Perfusion Imaging 490
Exercise Echocardiography 490
Comparison of Myocardial Perfusion Imaging with Two-Dimensional Echocardiography 491
Three-Dimensional and Doppler Flow EchocardioŁgraphy 491
Cardiac Magnetic Resonance Imaging and Ultrafast Computed Tomography Cardiac Scans 491
Pharmacologic Stress Testing 491
Diagnostic testing for cardiovascular disease in women 492
Summary 492
References 493
Chapter 116: Abdominal Aortic Aneurysm 493
Definition and epidemiology 493
Pathophysiology 493
Clinical presentation 494
Physical examination 494
Diagnostics 494
Differential diagnosis 495
Management 495
Preoperative Cardiac Risk Stratification 495
Open Surgical Repair 496
Endovascular Stent Grafts 496
Laparoscopic and Laparoscopically Assisted Aneurysm Surgery 497
Life span considerations 497
Complications 497
Indications for referral or hospitalization 497
Patient education 497
Health promotion 498
References 498
Chapter 117: Cardiac Arrhythmias 498
Tachyarrhythmias 499
Definition and epidemiology 499
Pathophysiology 499
Reentry 499
Abnormal or Enhanced Automaticity 499
Triggered Activity 499
Clinical presentation 499
Physical examination 500
Diagnostics 500
12-Lead Electrocardiogram 500
Holter Monitoring 500
Provocative Testing and Electrophysiologic Studies 500
Carotid Sinus Massage and Valsalva Maneuver 501
Echocardiography 501
Other Diagnostics 501
Differential diagnosis 501
Narrow QRS Tachycardia 501
Sinus Tachycardia 501
Premature Atrial Contractions 501
Premature Junctional Contractions 502
Multifocal Atrial Tachycardia 502
Paroxysmal Supraventricular Tachycardia 502
Atrioventricular Nodal Reentry Tachycardia 502
Atrioventricular Reentry Tachycardia 502
Atrial Flutter 502
Atrial Fibrillation 502
Wide QRS Tachycardia 502
Ventricular Tachycardia 502
Torsades de Pointes 503
Ventricular Fibrillation 503
Premature Ventricular Contractions 503
Management 504
Sinus Tachycardia 504
Multifocal Atrial Tachycardia 504
Paroxysmal Supraventricular Tachycardia 504
Atrial Fibrillation or Atrial Flutter 504
Premature Ventricular Contractions 505
Ventricular Tachycardia 506
Complications, indications for referral or hospitalization, and patient and family education 506
Bradyarrhythmias 506
Definition and epidemiology 506
Pathophysiology 506
Conduction Blocks 506
Clinical presentation 506
Physical examination 507
Diagnostics 507
Electrocardiography 507
Provocative Testing 507
Other Diagnostics 507
Differential diagnosis 507
Sinus Bradycardia 507
Sinoatrial Exit Block 507
Atrioventricular Nodal Block 507
Second Degree, Type I 507
Second Degree, Type II 507
Third-Degree AV Block 508
Bundle Branch Blocks 508
Hemiblocks 508
Management 508
Sinus Bradycardia 509
Sinoatrial Exit Block 509
Heart Blocks 509
Life span considerations 509
Complications 509
Indications for referral or hospitalization 509
Patient and family education 509
References 510
Chapter 118: Carotid Artery Disease 510
Pathophysiology 511
Clinical presentation 511
Risk Factors 511
Physical examination 512
Diagnostics 512
Differential diagnosis 512
Management 513
Medical Therapy 513
Carotid Endarterectomy 513
Carotid Endarterectomy for Symptomatic Patients 513
Carotid Endarterectomy for Asymptomatic Patients 513
Periprocedural Care 514
Complications of CEA 514
Carotid Angioplasty and Stenting 514
Procedure 515
Postprocedural Care 515
Complications of CAS 516
Life span considerations 516
Considerations for referral and hospitalization 516
Patient education 516
References 517
Chapter 119: Chest Pain and Coronary Artery Disease 518
Definition and epidemiology 518
Risk Factors for Coronary Artery Disease 518
Pathophysiology 518
Chronic Stable Angina 518
Silent Myocardial Ischemia (Asymptomatic Coronary Heart Disease) 518
Microvascular Angina 519
Variant Angina (Coronary Artery Spasm, Prinzmetal's Angina) 519
Unstable Angina and Non–ST-Segment Elevation Myocardial Infarction 519
Acute ST-Segment Elevation Myocardial Infarction 520
Clinical presentation 520
Chronic Stable Angina 520
Anginal Equivalents 521
Microvascular Angina 521
Variant Angina 521
Unstable Angina and Non–ST-Segment Elevation Myocardial Infarction 521
Acute ST-Segment Elevation Myocardial Infarction 522
Physical examination 522
Diagnostics 523
Chronic Stable Angina 523
Electrocardiography 523
Exercise Tolerance Testing (Stress Testing) 523
Part 12: Evaluation and Management of Gastrointestinal Disorders 612
Chapter 126: Abdominal Pain and Infections 612
Part 13: Evaluation and Management of Genitourinary Disorders 723
Chapter 144: Hypokalemia and Hyperkalemia 723
Definition and epidemiology 723
Pathophysiology 723
Clinical presentation 724
Physical examination 724
Diagnostics 724
Hypokalemia 724
Hyperkalemia 725
Differential diagnosis 725
Management 725
Acute Hypokalemia 726
Chronic Hypokalemia 726
Acute Hyperkalemia 726
Chronic Hyperkalemia 726
Complications 726
Indications for referral or hospitalization 726
Patient and family education 726
Part 14: Evaluation and Management of Gynecologic Concerns 794
Chapter 154: Amenorrhea 794
Definition and epidemiology 794
Pathophysiology 794
Clinical presentation 794
Physical examination 795
Diagnostics 795
Differential diagnosis 796
Primary Amenorrhea 796
Secondary Amenorrhea 796
Management 797
Life span considerations 798
Complications 798
Indications for referral or hospitalization 798
Patient and family education and health promotion 798
References 798
Chapter 155: Bartholin's Gland Cysts and Abscesses 799
Definition and epidemiology 799
Pathophysiology 799
Clinical presentation 799
Physical examination 799
Diagnostics 799
Differential diagnosis 799
Management 799
Antibiotics 799
Surgical Treatments 800
Incision and Drainage 800
Excision of Bartholin's Gland 800
Marsupialization and Window Operation 800
Catheter or Drain Placement 800
Carbon Dioxide Laser Therapy 800
Silver Nitrate 800
Life span considerations 800
Complications 800
Indications for referral or hospitalization 800
Patient and family education 800
References 800
Chapter 156: Breast Disorders 801
Risk assessment 801
Risk Factors 801
Risk Assessment Models 802
Genetic Testing 802
Risk Reduction 802
Screening recommendations 802
Breast Pain (Mastalgia, Mastodynia) 802
Definition and epidemiology 802
Pathophysiology 803
Clinical presentation 803
Physical examination 803
Diagnostics 803
Differential diagnosis 804
Management 804
Complications 804
Indications for referral or hospitalization 805
Patient education 805
Mastitis 805
Definition and epidemiology 805
Pathophysiology 805
Clinical presentation 805
Diagnostics 805
Differential diagnosis 805
Management 805
Complications 806
Indications for referral 806
Patient education 806
Nipple Discharge and Galactorrhea 806
Definition and epidemiology 806
Pathophysiology 806
Clinical presentation 806
Physical examination 806
Diagnostics 806
Differential diagnosis 807
Management 807
Co-Management with Specialists 808
Life span considerations 808
Indications for referral or hospitalization 808
Patient and family education 808
Paget's Disease of the Nipple 808
Pathophysiology 808
Clinical presentation 808
Physical examination 808
Diagnostics 808
Differential diagnosis 809
Management 809
Indication for referral 809
Patient education 809
Breast Masses 809
Definition and epidemiology 809
Pathophysiology 809
Clinical presentation 810
Physical examination 810
Diagnostics 810
Differential diagnosis 810
Management 810
Life span considerations 811
Indications for referral or hospitalization 811
Patient and family education 811
Gynecomastia 811
Definition and epidemiology 811
Pathophysiology 811
Clinical presentation 811
Physical examination 811
Diagnostics 811
Differential diagnosis 811
Management 812
Indications for referral or hospitalization 812
Patient and family education 812
References 812
Chapter 157: Chronic Pelvic Pain 812
Definition and epidemiology 812
Populations at Increased Risk of Chronic Pelvic Pain 812
Physical and Sexual Abuse 812
Pelvic Inflammatory Disease 813
Endometriosis 813
Interstitial Cystitis 813
Irritable Bowel Syndrome 813
Musculoskeletal Disorders 813
Postsurgical Pain 813
Pathophysiology 813
Clinical presentation 813
Physical examination 813
Diagnostics 814
Differential diagnosis 814
Management 815
Life span considerations 816
Complications 816
Indications for referral or hospitalization 816
Patient and family education 816
Health promotion 816
References 816
Chapter 158: Dysmenorrhea 817
Definition and epidemiology 817
Pathophysiology 817
Clinical presentation 818
Physical examination 818
Diagnostics 818
Differential diagnosis 818
Management 819
Complications 820
Indications for referral or hospitalization 820
Patient and family education 820
References 820
Chapter 159: Dyspareunia 820
Definition and epidemiology 820
Pathophysiology 820
Clinical presentation 821
Examination 821
Diagnostics 821
Differential diagnosis 822
Management and health promotion 822
Life span considerations 822
Complications 822
Indications for referral or hospitalization 822
Patient and family education 823
References 823
Chapter 160: Ectopic Pregnancy 823
Definition and epidemiology 823
Pathophysiology 823
Clinical presentation 823
Physical examination 824
Diagnostics 824
Differential diagnosis 824
Management 825
Life span considerations 825
Complications 825
Indications for referral or hospitalization 826
Patient and family education 826
References 826
Chapter 161: Fertility Control 826
Definition and epidemiology 826
Hormonal contraception 826
Oral Contraceptives 826
Progestin-Only Pills (Minipills) 828
Spironolactone Analogues 829
Injectable Contraception 829
Contraceptive Implants 829
Contraceptive Patch 829
Postcoital Contraception 830
Barrier methods 830
Condoms 830
Diaphragms and Cervical Caps 830
Spermicides 830
Cervical Sponge and Lea Contraceptive 831
Intrauterine Devices 831
Vaginal Ring 831
Surgical sterilization 831
Hysteroscopic sterilization 831
Natural family planning 831
Reasons for contraceptive nonuse 832
References 832
Chapter 162: Genital Tract Cancers 833
Endometrial Cancer 833
Definition and epidemiology 833
Pathophysiology 833
Clinical presentation and physical examination 833
Diagnostics and differential diagnosis 834
Management and indications for referral or hospitalization 834
Life span considerations 834
Patient and family education 834
Ovarian Cancer 834
Definition and epidemiology 834
Pathophysiology 835
Clinical presentation and physical examination 835
Diagnostics and differential diagnosis 835
Management and indications for referral or hospitalization 836
Life span considerations 836
Patient and family education 836
Vulvar Cancer 837
Definition and epidemiology 837
Pathophysiology 837
Clinical presentation and physical examination 837
Diagnostics and differential diagnosis 837
Part 15: Evaluation and Management of Musculoskeletal and Arthritic Disorders 887
Chapter 170: Ankle and Foot Pain 887
Ankle Sprains 887
Definition and epidemiology 887
Pathophysiology 887
Clinical presentation 887
Physical examination 887
Diagnostics 887
Differential diagnosis 888
Management 888
Complications 888
Indications for referral or hospitalization 888
Patient and family education 888
Achilles Tendinopathy 888
Definition and epidemiology 888
Part 16: Evaluation and Management of Neurologic Disorders 984
Chapter 187: Neuropsychological Evaluation 984
Overview of clinical neuropsychology 984
Professional functions and roles 984
Assessment tools and approaches 984
Neuropsychology within primary care settings 985
When to refer 986
Overview of the assessment process 987
Scoring and interpretation of neuropsychological test data 987
Additional considerations in neuropsychological assessment 988
Summary 988
References 988
Chapter 188: Amyotrophic Lateral Sclerosis 989
Definition and epidemiology 989
Pathophysiology 989
Clinical presentation and physical examination 989
Diagnostics 989
Differential diagnosis 990
Management 990
Life span considerations 990
Complications 991
Indications for referral or hospitalization 991
Patient and family education 991
References 991
Chapter 189: Bell's Palsy 992
Differential diagnosis 993
Management 993
Life span considerations 993
Complications 993
Indications for referral or hospitalization 994
Patient and family education 994
References 994
Chapter 190: Cerebrovascular Events 994
Definition and epidemiology 994
Pathophysiology 995
Ischemic Stroke 995
Hemorrhagic Stroke 995
Clinical presentation 995
Physical examination 995
Diagnostics 996
Differential diagnosis 997
Management 997
Thrombolytic Therapy 997
Surgery 998
Antiplatelet Agents 998
Life span considerations 998
Pregnancy 998
Geriatric Patients 998
Complications 998
Indications for referral or hospitalization 998
Prevention and patient education 999
References 999
Chapter 191: Delirium 999
Pathophysiology 1000
Clinical presentation 1000
Physical examination 1001
Diagnostics 1001
Differential diagnosis 1001
Management 1002
Complications 1002
Indications for referral or hospitalization 1003
Patient and family education 1003
References 1003
Chapter 192: Dementia 1003
Mild Cognitive Impairment 1004
Pathophysiology 1005
Alzheimer's Disease 1005
Vascular Dementia 1005
Lewy Body Dementia 1005
Clinical presentation 1005
Physical examination 1005
Diagnostics 1006
Differential diagnosis 1006
Management 1006
Complications 1007
Indications for referral or hospitalization 1007
Patient and family education 1007
References 1008
Chapter 193: Dizziness and Vertigo 1008
Clinical presentation 1009
Physical examination 1009
Diagnostics 1009
Differential diagnosis 1010
Management 1011
Complications 1011
Indications for referral or hospitalization 1011
Patient and family education 1011
Benign Paroxysmal Positional Vertigo 1011
Definition and epidemiology 1011
Pathophysiology 1011
Clinical presentation 1011
Physical examination 1012
Diagnostics 1012
Differential diagnosis 1012
Management 1012
Complications 1012
Indications for referral or hospitalization 1012
Patient and family education 1012
References 1012
Chapter 194: Guillain-Barré Syndrome 1013
Definition and epidemiology 1013
Pathophysiology 1013
Clinical presentation 1013
Physical examination 1013
Diagnostics 1014
Differential diagnosis 1014
Management 1014
Life span considerations 1015
Complications 1015
Consideration for referral or hospitalization 1015
Patient education 1015
References 1015
Chapter 195: Headache 1015
Clinical presentation 1016
Migraine 1016
Tension-Type Headache 1016
Cluster Headache 1016
Physical examination 1016
Diagnostics 1017
Differential diagnosis 1017
Management 1018
Nonpharmacologic Management 1018
Pharmacologic Management 1018
Preventive Therapy 1018
Abortive Therapy 1018
Life span considerations 1021
Complications 1021
Indications for referral or hospitalization 1021
Patient and family education 1021
Health promotion 1021
References 1021
Chapter 196: Infections of the Central Nervous System 1022
Diagnostics 1023
Differential diagnosis 1023
Management 1024
Complications 1024
Indications for referral or hospitalization 1024
Patient and family education 1024
Health promotion 1025
References 1025
Chapter 197: Movement Disorders and Essential Tremor 1025
Diagnostics 1026
Differential diagnosis 1026
Management 1026
Life span considerations 1026
Complications 1027
Indications for referral or hospitalization 1027
Patient and family education 1027
Essential Tremor 1027
Definition and epidemiology 1027
Pathophysiology 1027
Clinical presentation 1027
Physical examination 1028
Diagnostics 1028
Differential diagnosis 1028
Management 1028
Life span considerations 1028
Complications 1028
Indications for referral or hospitalization 1029
Patient and family education 1029
Health promotion 1029
References 1029
Chapter 198: Multiple Sclerosis 1029
Clinical presentation 1030
Physical examination 1030
Diagnostics 1030
Differential diagnosis 1030
Management 1031
Life span considerations 1032
Complications and indications for referral or hospitalization 1032
Patient and family education 1034
References 1034
Chapter 199: Parkinson's Disease 1035
Definition and epidemiology 1035
Pathophysiology 1035
Clinical presentation 1035
Physical examination 1035
Diagnostics 1036
Differential diagnosis 1036
Management 1036
Pharmacotherapy 1036
Selegiline 1036
Levodopa 1036
Dopamine Agonists 1037
Catechol O -Methyltransferase Inhibitors 1037
Anticholinergics 1037
Amantadine 1037
Surgery 1037
Deep Brain Stimulation (DBS) 1037
Complications and comorbid problems 1038
Psychosis and Hallucinations 1038
Dementia 1038
Depression 1038
Daytime Sleepiness and Fatigue 1038
Indications for referral or hospitalization 1038
Patient and family education 1038
References 1039
Chapter 200: Seizure Disorder 1039
Classification of seizures, epilepsy, and epileptic syndromes 1040
Clinical presentation 1041
Physical examination 1041
Diagnostics 1041
Differential diagnosis 1042
Initial stabilization and management of acute seizures 1042
Management 1043
Conservative Management 1043
Pharmacologic Management 1044
Surgical Management 1044
Life span considerations 1044
Complications 1047
Indications for referral or hospitalization 1047
Patient and family education 1047
Health promotion 1047
References 1047
Chapter 201: Trigeminal Neuralgia 1048
Management 1049
Complications 1049
Indications for referral or hospitalization 1050
Patient and family education 1050
References 1050
Chapter 202: Intracranial Tumors 1050
Etiology 1051
Clinical presentation 1051
Physical examination 1051
Diagnostics 1051
Differential diagnosis 1052
Management 1052
Life span considerations 1053
Complications 1053
Indications for referral or hospitalization 1053
Patient and family education 1053
Health promotion 1054
References 1054
Part 17: Evaluation and Management of Endocrine and Metabolic Disorders 1055
Chapter 203: Acromegaly 1055
Definition and epidemiology 1055
Pathophysiology 1055
Clinical presentation 1055
Physical examination 1055
Diagnostics 1056
Differential diagnosis 1056
Management and co-management with specialists 1056
Life span considerations 1057
Complications 1057
Indications for referral or hospitalization 1057
Patient education and health promotion 1057
References 1058
Chapter 204: Adrenal Gland Disorders 1058
Clinical presentation 1059
Physical examination 1059
Diagnostics 1059
Alternative Therapies 1061
Complications 1061
Indications for referral or hospitalization 1061
Patient education and health promotion 1061
References 1061
Chapter 205: Diabetes Mellitus 1062
Definition and epidemiology 1062
Pathophysiology 1062
Clinical presentation 1063
Physical examination 1063
Diagnostics 1064
Differential diagnosis 1064
Management 1065
Lifestyle Interventions 1065
Pharmacotherapy 1065
Insulin Therapy 1067
Type 1 Diabetes. 1067
Type 2 Diabetes 1068
Medications for Type 2 Diabetes 1068
Blood Glucose Monitoring 1071
Follow-Up Care 1072
Diabetes and Pregnancy 1072
Gestational Diabetes 1072
Pregnancy in the Woman with Type 1 Diabetes 1073
Pregnancy in the Woman with Type 2 Diabetes 1074
Co-Management with Specialists 1074
Complications 1075
Psychological Complications 1075
Acute Complications of Diabetes 1075
Hypoglycemia 1075
Hyperglycemia 1076
Diabetic Ketoacidosis and Hyperglycemic Hyperosmolar State 1076
Chronic Complications of Diabetes 1077
Microvascular Complications 1077
Diabetic Retinopathy 1077
Diabetic Nephropathy 1078
Diabetic Neuropathy 1078
Macrovascular Complications 1079
Indications for referral or hospitalization 1081
Life span considerations 1081
Education and health promotion 1082
Education and health promotion 1083
Chapter 206: Hirsutism 1083
Definition and epidemiology 1083
Pathophysiology 1084
Clinical presentation 1085
Physical examination 1085
Diagnostics 1086
Ovarian Source 1086
Adrenal Source 1086
Cortisol Excess 1087
Insulin Excess 1087
Prolactin Excess 1087
Pituitary Source 1087
Thyroid-Stimulating Hormone Excess 1087
5 α -Reductase Excess 1087
Amenorrhea 1087
Differential diagnosis 1087
Management 1088
Complications 1089
Indications for referral or hospitalization 1089
Life span considerations 1090
Education and health promotion 1090
References 1090
Chapter 207: Hypercalcemia and Hypocalcemia 1090
Definition and epidemiology 1090
Hypercalcemia 1091
Pathophysiology 1091
Clinical presentation 1091
Physical examination 1092
Diagnostics 1092
Differential diagnosis 1092
Management 1092
Life span considerations 1093
Complications 1093
Hypocalcemia 1093
Pathophysiology 1093
Clinical presentation 1093
Physical examination 1093
Diagnostics 1093
Differential diagnosis 1093
Management 1094
Life span considerations 1094
Complications 1094
Indications for referral or hospitalization 1094
Patient and family education and health promotion 1094
References 1095
Chapter 208: Hypernatremia and Hyponatremia 1095
Clinical presentation and physical examination 1096
Diagnostics 1096
Differential diagnosis 1096
Management 1096
Life span considerations 1097
Complications 1097
Indications for referral or hospitalization 1097
Patient and family education 1097
Hyponatremia 1097
Definition and epidemiology 1097
Pathophysiology 1098
Hyponatremia with Increased Extracellular Volume 1098
Hyponatremia with Decreased Extracellular Volume 1098
Hyponatremia with Normal Extracellular Volume 1098
Pseudohyponatremia 1098
Clinical presentation 1098
Physical examination 1099
Diagnostics 1099
Differential diagnosis 1099
Management 1099
Co-Management with Specialists 1100
Complications 1100
Indications for referral or hospitalization 1100
Patient and family education 1100
References 1101
Chapter 209: Lipid Disorders 1101
Definition and epidemiology 1101
Pathophysiology 1101
Low-Density Lipoprotein 1101
High-Density Lipoprotein 1102
Triglycerides 1102
Role of Lifestyle, Including Diet and Exercise 1102
Insulin Resistance, Diabetes, and Metabolic Syndrome 1102
Clinical evaluation 1103
Physical examination 1103
Diagnostics 1103
Differential diagnosis 1104
Management 1104
Risk Assessment 1104
Lifestyle Modification 1105
Diet 1108
Exercise 1108
Other Risk Factors 1109
Pharmacotherapy 1109
Pharmacotherapy for Specific Populations 1111
Young Adults 1111
Middle-Aged Men 1111
Middle-Aged Women 1111
Older Adults 1111
Metabolic Syndrome 1111
Complications 1111
Indications for referral 1111
Patient education 1111
References 1111
Chapter 210: Metabolic Syndrome 1112
Definition and epidemiology 1112
Pathophysiology 1112
Hypertension 1112
Dyslipidemia 1113
Prothrombotic State 1113
Proinflammatory State 1113
Microalbuminuria 1114
Other Pathophysiologic Effects 1114
Clinical presentation 1114
Physical examination 1114
Diagnostics 1114
Differential diagnosis 1114
Management 1115
Life span considerations 1117
Complications 1117
Indications for referral or hospitalization 1117
Patient and family education 1117
Health promotion 1117
References 1118
Chapter 211: Parathyroid Gland Disorders 1118
Pathophysiology 1119
Clinical presentation 1119
Physical examination 1120
Diagnostics 1120
Differential diagnosis 1121
Management 1121
Complications 1122
Indications for referral or hospitalization 1122
Life span considerations 1122
Patient education and health promotion 1122
References 1122
Chapter 212: Thyroid Disorders 1123
Thyroid function testing 1123
Goiter (Simple, Nontoxic) 1125
Definition and epidemiology 1125
Pathophysiology 1125
Clinical presentation 1125
Physical examination 1125
Diagnostics 1125
Differential diagnosis 1125
Management 1126
Complications 1126
Indications for referral or hospitalization 1126
Patient and family education and health promotion 1126
Thyroid Nodules and Thyroid Cancer 1126
Definition and epidemiology 1126
Pathophysiology 1126
Clinical presentation and physical examination 1126
Diagnostics and differential diagnosis 1127
Management 1127
Life span considerations 1128
Complications 1128
Indications for referral or hospitalization 1128
Patient and family education and health promotion 1128
Hyperthyroidism 1128
Definition and epidemiology 1128
Pathophysiology 1129
Clinical presentation and physical examination 1129
Diagnostics 1129
Differential diagnosis 1130
Management and life span considerations 1130
Graves' Disease 1130
Subclinical Hyperthyroidism 1131
Thyroiditis 1131
Subacute Thyroiditis 1131
Painless Postpartum Thyroiditis 1132
Toxic Nodule 1132
Toxic Multinodular Goiter 1132
Complications 1132
Indications for referral or hospitalization 1132
Patient and family education 1132
Hypothyroidism 1132
Definition and epidemiology 1132
Pathophysiology 1133
Clinical presentation 1133
Physical examination 1133
Diagnostics 1133
Differential diagnosis 1134
Management 1134
Subclinical Hypothyroidism 1134
Life span considerations 1135
Complications 1135
Indications for referral or hospitalization 1135
Patient and family education and health promotion 1135
Euthyroid Sick Syndrome 1135
Drugs and the Thyroid Gland 1136
Thyroid Disease in Pregnancy 1137
References 1137
Part 18: Evaluation and Management of Hematologic Disorders 1139
Chapter 213: Anemia 1139
Definition and epidemiology 1139
Pathophysiology 1139
Clinical presentation 1139
Diagnostics 1140
Differential diagnosis 1141
Microcytic Anemia 1141
Iron deficiency anemia 1141
Pathophysiology 1142
Clinical Presentation 1142
Physical Examination 1142
Diagnostics 1142
Differential Diagnosis 1143
Management 1143
Life Span Considerations 1144
Complications 1144
Indications for Referral or Hospitalization 1144
Patient and Family Education 1144
Health Promotion 1144
Thalassemia 1144
Definition and Epidemiology 1144
Pathophysiology 1145
Clinical Presentation 1145
Physical Examination 1146
Diagnostics 1146
Differential Diagnosis 1146
Management 1146
Life Span Considerations 1147
Complications 1147
Indications for Referral or Hospitalization 1147
Patient and Family Education 1148
Health Promotion 1148
Macrocytic Anemia: Megaloblastic Anemia 1148
Vitamin b 12 and folate deficiency 1148
Definition and Epidemiology 1148
Pathophysiology 1148
Clinical Presentation 1148
Physical Examination 1149
Diagnostics 1149
Differential Diagnosis 1149
Management 1149
Life Span Considerations 1149
Complications 1150
Indications for Referral or Hospitalization 1150
Patient and Family Education 1150
Health Promotion 1150
Normocytic Anemia 1150
Sickle cell disease 1150
Definition and Epidemiology 1150
Pathophysiology 1150
Clinical Presentation 1150
Physical Examination 1151
Diagnostics 1151
Differential Diagnosis 1151
Management 1151
Life Span Considerations 1152
Complications 1152
Indications for Referral or Hospitalization 1153
Patient and Family Education 1153
Health Promotion 1153
Anemia of Chronic Disease 1153
Pathophysiology 1153
Part 19: Evaluation and Management of Rheumatic and Multisystem Disorders 1182
Unit One: Rheumatic Disorders 1182
Chapter 218 Ankylosing Spondylitis and Related Disorders 1182
Ankylosing Spondylitis 1182
Definition and epidemiology 1182
Pathophysiology 1182
Clinical presentation 1182
Physical examination 1182
Diagnostics 1183
Differential diagnosis 1183
Management 1184
Life span considerations 1184
Complications 1184
Indications for referral or hospitalization 1184
Patient education 1185
Reactive Arthritis (Formerly Known as Reiter's Syndrome) 1185
Definition and epidemiology 1185
Pathophysiology 1185
Clinical presentation and physical examination 1185
Diagnostics 1186
Differential diagnosis 1186
Management 1186
Complications 1186
Indications for referral 1186
Patient education 1186
Psoriatic Arthritis 1186
Definition and epidemiology 1186
Pathophysiology 1186
Clinical presentation and physical examination 1186
Diagnostics 1187
Differential diagnosis 1187
Management 1187
Complications 1187
Indications for referral 1187
Patient education 1187
Arthritis of Inflammatory Bowel Disease 1188
Definition and epidemiology 1188
Pathophysiology 1188
Clinical presentation and physical examination 1188
Diagnostics 1188
Differential diagnosis 1188
Management 1188
Complications 1188
Indications for referral 1188
Patient education 1188
References 1188
Chapter 219 Polymyalgia Rheumatica and Giant Cell Arteritis 1189
Pathophysiology 1190
Clinical presentation 1190
Physical examination 1190
Diagnostics 1190
Differential diagnosis 1191
Management 1192
Life span considerations 1192
Complications 1192
Considerations for referral or hospitalization 1193
Patient education 1193
References 1193
Chapter 220 Raynaud's Phenomenon 1194
Definition and epidemiology 1194
Pathophysiology 1194
Clinical presentation 1194
Physical examination 1194
Diagnostics 1194
Differential diagnosis 1194
Management 1195
Complications 1195
Indications for referral or hospitalization 1195
Patient education 1196
References 1196
Chapter 221 Rheumatoid Arthritis 1196
Clinical presentation 1197
Physical examination 1197
Diagnostics 1197
Radiographs 1197
Synovial Fluid Analysis 1198
Differential diagnosis 1198
Management 1198
Cardiovascular Risk 1198
Pharmacologic Agents 1198
Disease-Modifying Antirheumatic Drugs 1198
Glucocorticoids 1199
NSAIDs 1199
Nonpharmacologic Treatment 1199
Co-Management with Specialists 1199
Life span considerations 1199
Complications 1199
Indications for referral or hospitalization 1199
Patient and family education 1199
References 1200
Chapter 222 Systemic Lupus Erythematosus 1201
Definition and epidemiology 1201
Pathophysiology 1201
Clinical presentation and physical examination 1201
Diagnostics 1203
Differential diagnosis 1203
Management 1203
Life span considerations 1205
Complications 1205
Indications for referral or hospitalization 1205
Patient and family education 1206
References 1206
Chapter 223 Vasculitis 1206
Classification of vasculitic syndromes 1207
Pathophysiology 1207
Clinical presentation and physical examination 1207
Diagnostics 1209
Differential diagnosis 1210
Management 1210
Complications 1210
Indications for referral or hospitalization 1211
Patient and family education 1211
References 1211
Unit Two: Multisystem Disorders 1211
Chapter 224 Barotrauma and Other Diving Injuries 1211
Pathophysiology 1212
Clinical presentation 1212
Physical examination 1212
Differential diagnosis 1212
Management 1212
Life span considerations 1213
Complications 1213
Indications for referral 1213
Patient education 1213
Ear Barotrauma 1214
Part 20: Evaluation and Management of Infectious Diseases 1242
Chapter 230: Emerging and Reemerging Infectious Diseases 1242
Definitions 1242
Epidemiology 1242
Pathogens 1243
Acute Respiratory Diseases 1243
Human Metapneumovirus 1243
Severe Acute Respiratory Syndrome (SARS) 1243
Influenza A (H1N1) 1243
Avian Influenza A (H5N1) 1245
Acute Diarrheal Illnesses 1245
Vibrio Cholerae 1245
Escherichia Coli O157:H7 1245
Vector-Borne Diseases 1246
Lyme Disease 1246
West Nile Virus 1246
Dengue Fever 1246
Chikungunya Fever 1246
Tick-Borne Encephalitis (TBE) 1246
Zoonosis 1247
Monkeypox 1247
Antibiotic Resistance 1247
Methicillin-Resistant Staphylococcus Aureus (MRSA) 1248
Extremely Drug-Resistant Tuberculosis (XDR-TB) 1248
References 1249
Chapter 231: Fever 1250
Definition and epidemiology 1250
Presentations of elevated body temperature 1250
Approach to evaluation of a febrile patient 1250
Evaluation of Fever Without Clear Etiology 1250
Diagnostic Evaluation for Fever Without Clear Etiology 1251
Evaluation of Fever of Unknown Origin 1252
Diagnostic Evaluation for Fever of Unknown Origin 1252
Life span considerations 1252
Management 1252
Indications for referral or hospitalization 1252
Patient and family education 1252
References 1252
Chapter 232: HIV Infection 1253
Definition and epidemiology 1253
Pathophysiology 1254
Clinical presentation 1254
Diagnostics 1255
Diagnosis of HIV Infection 1255
Laboratory and Other Testing of the Patient with Newly Diagnosed HIV Infection 1256
Differential diagnosis 1257
Management 1257
Life span considerations 1260
Complications 1260
Metabolic Toxicities 1260
Lipodystrophy 1260
Liver Disease 1260
Drug Interactions 1260
Iris 1260
Indications for referral or hospitalization 1260
Patient and family education 1261
References 1261
Chapter 233: Influenza 1261
Definition and epidemiology 1261
Pathophysiology 1261
Clinical presentation 1262
Physical examination 1262
Diagnostics 1262
Differential diagnosis 1262
Management 1262
Life span considerations 1262
Complications 1262
Indications for referral or hospitalization 1263
Patient and family education 1263
Health promotion and prevention 1263
References 1263
Chapter 234: Infectious Diarrhea 1263
Definition 1263
Epidemiology 1264
Pathophysiology 1264
Clinical presentation 1265
Physical examination 1265
Diagnostics 1266
Differential diagnosis 1266
Noninflammatory Diarrhea: Acute Gastroenteritis 1266
Traveler's Diarrhea 1266
Vibrio Cholerae 1267
Inflammatory Diarrhea 1267
Shigella (S. Dysenteriae, S. Flexneri, S. Sonnei) 1267
Salmonella (Non- Typhi Species) 1268
Campylobacter Jejuni 1268
Escherichia Coli O 157:H7 1268
Clostridium Difficile 1268
Food Poisoning: Bacterial Toxins 1269
One to Six Hours After Ingestion 1269
Staphylococcus Aureus Food Poisoning 1269
Part 21: Evaluation and Management of Oncologic Disorders 1298
Chapter 239: Collaborative Management of the Oncology Patient 1298
Cancer risks 1298
Screening for cancer 1298
Patient management issues 1298
Role of the primary health care provider 1299
References 1299
Chapter 240: Basic Principles of Oncology Treatment 1299
Radiation therapy 1300
External Beam Radiotherapy 1300
Brachytherapy 1300
CT Simulation and Its Role in Radiotherapy 1300
Fractionation 1300
Radiation Treatment Side Effects 1301
Summary 1301
Chemotherapy 1301
Carcinogenesis, Cellular Kinetics, and Chemotherapy 1301
Role of Chemotherapy in Oncology 1301
Response to Chemotherapy 1302
Other anticancer therapies 1303
References 1303
Chapter 241: Oncology Complications and Paraneoplastic Syndromes 1303
Superior Vena Cava Syndrome 1303
Definition and epidemiology 1303
Pathophysiology 1303
Part 22: Evaluation and Management of Mental Health Disorders 1323
Chapter 244: Eating Disorders 1323
Definition and epidemiology 1323
Pathophysiology 1323
Clinical presentation 1323
Physical examination 1323
Diagnostics 1324
Differential diagnosis 1324
Management 1324
Complications 1326
Indications for referral or hospitalization 1326
Life span considerations 1327
Index 1367
Table of Contents by Disorder 1397