BOOK
Early Diagnosis and Treatment of Cancer Series: Colorectal Cancer E-Book
Susan Gearhart | Nita Ahuja | Stephen C. Yang
(2010)
Additional Information
Book Details
Abstract
Each volume in the Early Detection and Treatment of Cancer Series is packed with practical, authoritative information designed to cover the full range of diagnostic procedures, including pathologic, radiologic, bronchoscopic, and surgical aspects. You’ll be able to determine the safest, shortest, least invasive way to reach an accurate diagnosis; stage the disease; and choose the best initial treatment for early stages. Based on current evidence in the literature, authors provide clinical, hands-on tools to help you make informed decisions on precisely what tests and imaging studies are needed to diagnose and stage each type of cancer. Practical, authoritative, and highly-illustrated, this volume in the brand new Early Detection and Treatment of Cancer series covers current protocols and the latest advances in diagnostic imaging and molecular and serologic markers for colon cancer. Apply expert advice on the best “next-step” plan for different presentations and tips for less invasive protocols. Get clinical, hands-on tools to help you make informed decisions on precisely what tests and imaging studies are needed for accurate diagnosis and staging. Clear figures, tables, and boxes illustrate step-by-step care of the full range of problems encountered. The small size and convenient format make this an ideal purchase for diagnostic reference.
- Outlines the steps after diagnosis to guide you through formulating a treatment or patient care plan.
- Emphasizes important points—such as risk-adjusted screening for staging and the use of promising new gene therapies—with “key points” boxes at the beginning of each chapter and pedagogic features throughout.
- Summarizes the process of accurately diagnosing and staging cancer in a logical, almost algorithmic, approach for easy reference.
- Complements the procedures outlined in the text with full-color photographs and line drawings to reinforce your understanding of the material.
Table of Contents
| Section Title | Page | Action | Price |
|---|---|---|---|
| Front Cover | Cover | ||
| Early Diagnosis and Treatment of Cancer: Colorectal Cancer | iii | ||
| Copyright Page | iv | ||
| Table of Contents | xi | ||
| Dedication | v | ||
| Series Preface | vii | ||
| Preface | ix | ||
| Contributors | xiii | ||
| Chapter 1. Epidemiology and Risk Factors of Colorectal Cancer | 1 | ||
| Epidemiology | 1 | ||
| Risk Factors | 5 | ||
| Mortality | 8 | ||
| Economic Burden of Disease | 9 | ||
| Conclusion | 9 | ||
| References | 10 | ||
| Chapter 2. Presentation andInitial Evaluation ofColorectal Cancer | 13 | ||
| Presentation | 13 | ||
| Initial Evaluation | 16 | ||
| Conclusion | 18 | ||
| References | 18 | ||
| Chapter 3. Hereditary Colorectal Cancerand Polyp Syndromes | 21 | ||
| Introduction | 21 | ||
| Hereditary NonpolyposisColorectal Cancer | 21 | ||
| Familial Adenomatous Polyposis | 24 | ||
| MYH-Associated Polyposis | 25 | ||
| APC I1307K Mutation | 26 | ||
| Familial/Juvenile Polyposis Coli | 26 | ||
| Cowden Syndrome | 27 | ||
| Bannayan-Riley-Ruvalcaba Syndrome(Bannayan-Zonana Syndrome) | 28 | ||
| Peutz-Jeghers Syndrome | 28 | ||
| References | 29 | ||
| Chapter 4. Genetic Screening | 31 | ||
| Introduction | 31 | ||
| Proper Use of Clinical Genetic Testing | 31 | ||
| The Genetic Counseling Process | 33 | ||
| Genetic Testing for ColorectalCancer Syndromes | 36 | ||
| Genetic Testing for Juvenile Polyposis | 43 | ||
| Conclusion | 44 | ||
| References | 45 | ||
| Chapter 5. Behavior and DietaryModifi cation in the Preventionof Colon Cancer | 47 | ||
| Introduction | 47 | ||
| Macronutrients | 48 | ||
| Vitamins and Micronutrients | 53 | ||
| Lifestyle | 55 | ||
| Conclusion | 59 | ||
| References | 59 | ||
| Chapter 6. Chemoprevention ofColorectal Cancer | 65 | ||
| Introduction | 65 | ||
| Nonsteroidal Anti-infl ammatory Drugs | 65 | ||
| Ursodeoxycholic Acid | 68 | ||
| Hormones | 69 | ||
| Minerals and Vitamins | 70 | ||
| Curcumin | 71 | ||
| Diet and Exercise | 71 | ||
| References | 72 | ||
| Chapter 7. Fecal Occult Blood Test | 75 | ||
| Introduction | 75 | ||
| Types of Fecal Occult Blood Tests | 75 | ||
| General Advantages and Disadvantagesof Fecal Occult Blood Tests | 76 | ||
| Specifi c Characteristics ofthe g-FOBT and FIT | 79 | ||
| Conclusions | 80 | ||
| References | 80 | ||
| Chapter 8. Colonoscopy and FlexibleSigmoidoscopy in ColorectalCancer Screening andSurveillance | 83 | ||
| Introduction | 83 | ||
| Indications for Screening | 83 | ||
| Findings on Endoscopic Evaluation | 86 | ||
| Screening and Surveillance Tools | 86 | ||
| Current Recommendations | 88 | ||
| Special Populations | 90 | ||
| New Directions | 90 | ||
| Conclusion | 91 | ||
| References | 91 | ||
| Chapter 9. Stool and Blood Samplingfor Early Detection ofColorectal Cancer | 93 | ||
| Introduction | 93 | ||
| Screening Blood | 97 | ||
| Screening Stool | 98 | ||
| Conclusion | 102 | ||
| References | 102 | ||
| Chapter 10. Radiologic Techniques:Virtual Colonoscopy | 107 | ||
| Introduction | 107 | ||
| Principles and Supporting Literature | 107 | ||
| Technique | 108 | ||
| Interpretation Strategies | 111 | ||
| Reporting | 111 | ||
| Current Controversies | 115 | ||
| Future Directions | 115 | ||
| Conclusions | 116 | ||
| References | 116 | ||
| Chapter 11. Preoperative Evaluation | 117 | ||
| Preoperative Preparation | 117 | ||
| Specifi c Medical Considerations | 119 | ||
| Postoperative Analgesia | 122 | ||
| Conclusion | 124 | ||
| References | 124 | ||
| Chapter 12. Limited Resection: Indications,Techniques, and Outcomes ofTransanal Excision andTransanal EndoscopicMicrosurgery | 127 | ||
| Introduction | 127 | ||
| Long-term Outcomes AfterLocal Excision | 128 | ||
| Patient Selection | 128 | ||
| Operative Techniques | 130 | ||
| Radical Resection ImmediatelyAfter Local Excision | 131 | ||
| Follow-up and Salvage TherapyAfter Local Excision | 131 | ||
| Conclusion | 132 | ||
| References | 132 | ||
| Chapter 13. Endoscopic Techniques inColorectal Neoplasia | 135 | ||
| Introduction | 135 | ||
| Endoscopic Resection | 135 | ||
| Colorectal Self-Expandable Metal Stents | 139 | ||
| References | 144 | ||
| Chapter 14. Open Surgical Techniquesin Colorectal Cancer | 145 | ||
| Introduction | 145 | ||
| Surgical Oncologic Principles:Historical Perspective | 145 | ||
| Staging the Extent of Cancer Resection | 147 | ||
| Lymphadenectomy | 147 | ||
| Colon | 148 | ||
| Rectum | 154 | ||
| References | 165 | ||
| Chapter 15. Systemic Therapy forColon Cancer | 167 | ||
| Introduction | 167 | ||
| Metastatic Colorectal Cancer | 167 | ||
| Duration of Therapy | 176 | ||
| Adjuvant Systemic Therapy | 177 | ||
| Future Directions | 179 | ||
| References | 180 | ||
| Chapter 16. Radiation Therapy forColorectal Adenocarcinoma:External Beam andIntraoperative RadiationTherapy | 185 | ||
| Background | 185 | ||
| External Beam Radiation Therapyfor Rectal Cancer | 186 | ||
| Intraoperative Radiation Therapy:Overview | 187 | ||
| HDR-IORT for Locally AdvancedRectal Cancer | 193 | ||
| Locally Recurrent Rectal Cancer | 194 | ||
| Re-irradiation | 195 | ||
| IORT Toxicity | 195 | ||
| Functional Outcome and Quality of Life | 196 | ||
| Role of Adjuvant EBRT in LocallyAdvanced Colon Cancer | 196 | ||
| Conclusions and Future Directions | 197 | ||
| References | 198 | ||
| Chapter 17. Surveillance and Follow-up | 201 | ||
| Introduction | 201 | ||
| Overview of Prospective Evidence | 203 | ||
| Frequency and Duration | 206 | ||
| History and Physical Examination | 207 | ||
| Carcinoembryonic Antigen Testing | 208 | ||
| Computed Tomography | 212 | ||
| Colonoscopy | 213 | ||
| Positron Emission Tomography | 215 | ||
| Summary | 215 | ||
| References | 216 | ||
| Chapter 18. Clinical Trials: Why Participate | 219 | ||
| Introduction | 219 | ||
| Types of Clinical Trials | 219 | ||
| Phases of a Clinical Trial | 220 | ||
| Clinical Trial Designs | 220 | ||
| Participation in a Clinical Trial | 221 | ||
| Multicenter Clinical Trial | 222 | ||
| References | 223 | ||
| Chapter 19. Vaccines and Immunotherapy | 225 | ||
| Introduction | 225 | ||
| Immunotherapy—An Overview | 225 | ||
| Immunotherapy and Metastases | 235 | ||
| Conclusion | 236 | ||
| References | 236 | ||
| Chapter 20. Genetic Profi ling inColorectal Cancer | 239 | ||
| Introduction | 239 | ||
| Types of Genetic Profi ling | 240 | ||
| Practical Issues in Genetic Profi ling | 244 | ||
| Future Directions | 248 | ||
| References | 248 | ||
| Chapter 21. Coping with Colorectal Cancer | 251 | ||
| Introduction | 251 | ||
| Physical and Psychosocial Aspectsof Colorectal Cancer | 251 | ||
| Perspective and Concerns of the Patient | 253 | ||
| Types of Cancer Support Resources | 255 | ||
| Other Considerations After a Diagnosisof Colorectal Cancer | 256 | ||
| Late Effects versus Long-Term SideEffects of Cancer Treatment | 256 | ||
| What Is It Like to Be a Cancer Survivor | 256 | ||
| The Caregiver’s Perspective | 258 | ||
| ConclusionDespite advances | 259 | ||
| References | 259 | ||
| Websites | 259 | ||
| Chapter 22. Conclusion | 261 | ||
| References | 261 | ||
| Index | 263 |