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Emerging Respiratory Infections in the 21st Century, An Issue of Infectious Disease Clinics - E-Book

Emerging Respiratory Infections in the 21st Century, An Issue of Infectious Disease Clinics - E-Book

Alimuddin Zumla | Wing-Wai Yew | David S.C. Hui

(2010)

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Book Details

Abstract

Respiratory infections are among the most common causes of morbidity and mortality worldwide. These infections present a special challenge to physicians for several reasons, including of the recent disasters caused by severe acute respiratory syndrome (SARS) and bird and swine influenza, the increase in viral and bacterial resistance to currently available anti-microbial drugs, the increased frequency of new viral lung infections in clinical practice, and the worldwide emergence of deadly drug-resistant forms of TB. For these reasons, it is important for infectious disease specialists to have an overview of emerging respiratory infections.

Table of Contents

Section Title Page Action Price
Front Cover Cover
Contributors iii
Contents vii
Preface xiii
Erratum xvii
Chapter 1. Emerging Bacterial, Fungal, and Viral Respiratory Infections in Transplantation 541
EMERGING BACTERIAL RESPIRATORY INFECTIONS IN TRANSPLANTATION 542
EMERGING FUNGAL RESPIRATORY INFECTIONS IN TRANSPLANTATION 544
EMERGING VIRAL RESPIRATORY INFECTIONS IN TRANSPLANTATION 547
SUMMARY 549
REFERENCES 549
Chapter 2. Common and Emerging Fungal Pulmonary Infections 557
ENDEMIC MYCOSES 558
EMERGING PULMONARY MOLD INFECTIONS 568
EMERGING PULMONARY YEAST INFECTION: CRYPTOCOCCUS GATTII 570
SUMMARY 572
REFERENCES 572
Chapter 3. Emerging and Established Parasitic Lung Infestations 579
PROTOZOAL PARASITES 579
HELMINTHIC PARASITES 584
SUMMARY 595
REFERENCES 596
Chapter 4. Emerging, Novel, and Known Influenza Virus Infections in Humans 603
INFLUENZA VIRUSES 603
INFLUENZA PANDEMICS 605
CLINICAL FEATURES, DIAGNOSIS, AND MANAGEMENT OF INFLUENZA 607
PUBLIC HEALTH ISSUES: PREVENTION AND CONTROL 612
SUMMARY 614
REFERENCES 614
Chapter 5. Severe Acute Respiratory Syndrome and Coronavirus 619
THE VIRUS AND ITS ORIGIN 619
EPIDEMIOLOGY 620
CLINICAL FEATURES 621
LABORATORY FEATURES 623
RADIOLOGICAL FEATURES 623
PATHOGENESIS 623
IMMUNOBIOLOGY 625
TREATMENT 625
OUTCOMES 628
VACCINE DEVELOPMENT 629
SUMMARY 630
REFERENCES 630
Chapter 6. Respiratory Infections Due to Drug-Resistant Bacteria 639
CAP 640
HAP 643
REFERENCES 647
Chapter 7. Occupation-Related Respiratory Infections Revisited 655
RISK AND RISK FACTORS FOR TB INFECTION AND DISEASE 656
INTERVENTIONS TO PREVENT NOSOCOMIAL TB TRANSMISSION 658
SARS 664
INFLUENZA 669
SUMMARY 670
REFERENCES 671
Chapter 8. Pulmonary Infectious Complications of Tumor Necrosis Factor Blockade 681
TNF ANTAGONISTS 681
GRANULOMATOUS INFECTIONS 682
VIRAL INFECTIONS 683
STRUCTURE–FUNCTION RELATIONSHIP 684
LTBI DIAGNOSIS AND TREATMENT 684
MANAGEMENT OF INCIDENT TB CASES 685
REFERENCES 687
Chapter 9. The Convergence of the Global Smoking, COPD, Tuberculosis, HIV, and Respiratory Infection Epidemics 693
METHODOLOGY AND SEARCH STRATEGY 694
SMOKING AND PULMONARY IMMUNITY AND DISEASE 694
SMOKING AND TB 695
SMOKING AND PNEUMONIA 697
SMOKING AND INFLUENZA 697
SMOKING AND HIV 698
SMOKING AND COPD 698
CONVERGENCE OF TB, HIV, COPD, PNEUMONIA, AND INFLUENZA 698
SUMMARY 699
REFERENCES 699
Chapter 10. Extensively Drug-resistant Tuberculosis: Epidemiology and Management Challenges 705
INSIGHTS FROM CLINICAL EPIDEMIOLOGY 706
INSIGHTS FROM MOLECULAR EPIDEMIOLOGY 707
DIAGNOSIS OF MDR AND XDR-TB 712
MANAGEMENT CHALLENGES 717
ETHICAL DILEMMAS 718
SUMMARY 719
REFERENCES 720
Chapter 11. Childhood Tuberculosis: An Emerging and Previously Neglected Problem 727
EVIDENCE OF EMERGENCE 728
INCREASED AWARENESS 730
PROGRAMMATIC BARRIERS 731
DIAGNOSTIC DILEMMA 732
TB AND HIV COINFECTION 738
TREATING CHILDREN WITH TB 740
DRUG RESISTANCE 742
RESEARCH PRIORITIES 745
SUMMARY 745
REFERENCES 745
Chapter 12. Tuberculosis in the Global Aging Population 751
EPIDEMIOLOGIC TRANSITION OF TUBERCULOSIS 751
RISK FACTORS FOR TB 756
PREVENTIVE TREATMENT 758
OTHER PREVENTION STRATEGIES 762
CLINICAL DISEASE AMONG THE ELDERLY 763
FUTURE PERSPECTIVE 765
Chapter 13. Nontuberculous Mycobacterial Lung Diseases 769
EPIDEMIOLOGY 769
PATHOGENESIS 772
CLINICAL FEATURES 774
DISEASE PATTERNS WITH NTM OTHER THAN MAC 777
DIAGNOSIS 778
TREATMENT 780
SUMMARY 784
REFERENCES 784
Chapter 14. Emerging Advances in Rapid Diagnostics of Respiratory Infections 791
ANTIGEN DETECTION 792
NUCLEIC ACID AMPLIFICATION TESTS 793
BREATH ANALYSIS 800
FUTURE PROSPECTS 801
REFERENCES 801
Chapter 15. Antiviral Drug Resistance: Mechanisms and Clinical Implications 809
HERPESVIRUSES 809
HERPES SIMPLEX VIRUS 811
VARICELLA ZOSTER VIRUS 812
CYTOMEGALOVIRUS 813
HEPATITIS B VIRUS 817
THE FUTURE 821
Index 835