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Orthopaedic Pathology E-Book

Orthopaedic Pathology E-Book

Peter G. Bullough

(2009)

Additional Information

Book Details

Abstract

Orthopaedic Pathology, 5th Edition, by Peter G. Bullough, MB, ChB, presents a unique, lavishly illustrated account of the pathology of arthritic disorders, metabolic disturbances, and soft tissue and bone tumors. Nearly 2,000 high-quality pathologic slides, diagnostic images, and gross specimens-side-by-side-depict the appearance of a wide range of conditions and correlate orthopaedic pathology to clinical practice for greater diagnostic accuracy. It’s the ideal resource for the orthopaedic surgeon and radiologist as well as the trainee and practicing pathologist.

  • Provides extensive coverage of arthritic disorders, metabolic disturbances, soft tissue tumors, bone tumors, and rare disorders-not just tumors, which most books emphasize-for guidance on the most commonly seen conditions.
  • Uses nearly 2000 high-quality illustrations-including pathology, histology, radiologic imaging, and schematic line diagrams-that present a clear visual correlation between pathology and clinical images to aid in diagnosis.
  • Includes a chapter on imaging techniques, interpretation, and strategies that provides a foundation of knowledge in radiology.
  • Features brief text, including bulleted lists of key points and information, that makes reference quick and learning easy.
  • Offers updated coverage of immunohistochemistry and molecular pathology-along with examples from the latest imaging and pathologic techniques-to help you recognize the presentation of disorders using these approaches.
  • Features discussions of some rare conditions, equipping you to diagnose even the least common orthopaedic disorders.

Table of Contents

Section Title Page Action Price
Front Cover\r Cover
Orthopaedic Pathology 584
Copyright Page\r 584
Table of Contents 584
Dedication\r v
Contributors\r 584
Preface\r 584
Section I: Normal 1
Chapter 1. Normal Skeletal Structure and Development 1
Matrix 2
Bones 7
Joints 18
Bone Growth and Development 29
Chapter 2. Methods of Examination 41
Gross Examination 42
Microscopic Examination 43
Role of Frozen Section in Orthopaedics 52
Chapter 3. Imaging Techniques, Interpretation, and Strategies 53
Imaging Methods 54
Morphologic Abnormalities of Bone 60
Bone Tumors and Tumor-Like Bone Lesions 65
Imaging Strategies in Bone Lesions, with Particular Emphasis on Bone Tumors 70
Imaging Strategies in Soft Tissue Tumors 75
Joint Disorders 78
Section II: Response to Injury 81
Chapter 4. The Effects of Injury and the Inflammatory Response 81
Effects of Injury 82
The Inflammatory Response 88
Summary 108
Chapter 5. Bone and Joint Infection 109
Pyogenic Infections and Other Nongranulomatous Inflammatory Conditions 110
Granulomatous Inflammation of Bones and Joints 127
Section III: Metabolic Disturbances 141
Chapter 6. Diseases Resulting from Synthesis of Abnormal Matrix Components 141
Disturbances in Collagen Synthesis 142
Mucopolysaccharidoses 152
Disturbances in Mineral Formation 156
Dwarfism (Chondro-osseous Dysplasia) 158
Chapter 7. Diseases Resulting from Disturbances in Cell Linkage 161
Osteosclerotic Conditions 162
Osteopenic Conditions 175
Chapter 8. Bone Disease Resulting from Disturbances in Mineral Homeostasis 189
Calcium and Phosphorus Homeostasis 190
Hypercalcemia 192
Hypocalcemia 200
Soft Tissue Calcification 205
Chapter 9. Accumulation of Abnormal Metabolic Products and Various Hematologic Disorders 211
Deposition and Storage Diseases 212
Skeletal Manifestations of Hematologic Diseases 220
Section IV: Arthritis 231
Chapter 10. The Dysfunctional Joint 231
Function and Anatomy 232
Normal Joint Physiology 234
The Pathophysiology of a Dysfunctional Joint 235
Chapter 11. The Noninflammatory Arthritides 253
Osteoarthritis (Degenerative Joint Disease) 254
Ochronosis (Alkaptonuria) 265
Arthritis Secondary to Subchondral Insufficiency Fracture 266
Rapidly Destructive Osteoarthritis 269
Osteochondritis Dissecans 273
Slipped Capital Femoral Epiphysis (Adolescent Coxa Vara) 274
Congenital Dislocation of the Hip\r 275
Chapter 12. The Inflammatory Arthritides 279
Inflammatory Arthritis Associated with Diffuse Connective Tissue Disease 280
Diseases Resulting from Deposition of Metabolic Products in Joint Tissues 289
Chapter 13. Disc Disease and Spinal Arthritis 303
Displacement of Disc Tissue 304
Degenerative Arthritis 310
Inflammatory Arthritis 314
Ankylosing Spondyloarthropathies 315
Chapter 14. Tissue Response to and Complications of Orthopaedic Implants 321
Usual Tissue Response to Clinically Nonfailed Articular Implants 326
Morbidity Associated with Total Joint Replacements 327
Tumors and Pseudotumors 329
Tissue Responses Around Noninfected, Clinically Failed Articular Implants 331
Chapter 15. Bone Infarction (Osteonecrosis) 343
Skeletal Manifestation of Decompression Sickness (Caisson Disease) 345
Bone Infarctions Not Associated with Caisson Disease 346
Osteonecrosis of the Femoral Head 346
Staging of Osteonecrosis of the Femoral Head 348
Legg-Calvé-Perthes Disease 355
Idiopathic, Nontraumatic or Primary Osteonecrosis of the Femoral Head 358
Section V: Bone Tumors 361
Chapter 16. Bone-Forming Tumors and Tumor-Like Conditions 361
Reactive or Post-Traumatic Lesions that may be Mistaken for Malignant Tumors 362
Benign Tumors 364
Malignant Tumors 376
Chapter 17. Cartilage-Forming Tumors and Tumor-Like Conditions 399
Benign Tumors 400
Benign Neoplasms 405
Malignant Neoplasms 417
Chapter 18. Fibrous Tumors and ­ Tumor-Like Conditions 429
Reactive or Post-Traumatic Tumors 430
Benign Neoplasms 432
Malignant Neoplasms 443
Chapter 19. Benign Nonmatrix-Producing Bone Tumors 449
Reactive or Post-Traumatic Tumors 450
Benign Tumors Including Neoplasms 453
Chapter 20. Malignant Nonmatrix-Producing Bone Tumors 477
Ewing’s Sarcoma (Primitive Neuroectodermal Tumor) 478
Immunohematopoietic Neoplasms 481
Vascular Neoplasms 485
Metastatic Cancer 492
Section VI: Soft Tissue Tumors 497
Chapter 21. Benign Soft Tissue Tumors 497
Benign Synovial Lesions\r 498
Benign Fibrous Lesions\r 506
Peripheral Nerve Lesions\r 518
Miscellaneous Lesions\r 521
Chapter 22. Malignant Soft Tissue Tumors 533
Malignant Fibrous Histiocytoma 534
Liposarcoma 535
Rhabdomyosarcoma 537
Synovial Sarcoma 539
Fibrosarcoma 541
Ossifying Fibromyxoid Tumor of Soft Tissue 542
Malignant Peripheral Nerve Sheath Tumors (Malignant Neurilemoma) 543
Epithelioid Sarcoma 546
Soft Tissue (Extraskeletal) Osteosarcoma 546
Extraskeletal Myxoid Chondrosarcoma (Chordoid Tumor) 547
Further Reading 551
General 551
Section I Normal 551
Section II: Response to Injury 552
Section III: Metabolic Disturbances 553
Section IV: Arthritis 556
Section V: Bone Tumors 558
Section VI: Soft Tissue Tumors 562
Index 565