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Nuclear Medicine: The Requisites E-Book

Nuclear Medicine: The Requisites E-Book

Harvey A. Ziessman | Janis P. O'Malley | James H. Thrall

(2013)

Additional Information

Book Details

Abstract

Get the essential tools you need to make an accurate diagnosis with Nuclear Medicine: The Requisites! The newest edition of his bestselling volume by Drs. Harvey Ziessman, Janis O'Malley, and James Thrall delivers the conceptual, factual, and interpretive information you need for effective clinical practice in nuclear medicine imaging, as well as for certification and recertification review.

  • Prepare for the written board exam and for clinical practice with critical information on nuclear medicine physics, detection and instrumentation, SPECT and PET imaging, and clinical nuclear medicine imaging.

Table of Contents

Section Title Page Action Price
Front Cover Cover
IFC IFC
Nuclear Medicine: The Requisites iii
Copyright iv
Contributor v
Foreword vii
Preface ix
Contents xi
Part I Basic Principles 1
Chapter 1 Radiopharmaceuticals 1
ELEMENTS, RADIONUCLIDES, AND RADIOPHARMACEUTICALS 1
PRODUCTION OF RADIONUCLIDES 1
RADIONUCLIDE GENERATORS 2
TECHNETIUM CHEMISTRY AND RADIOPHARMACEUTICAL PREPARATION 5
QUALITY ASSURANCE OF TECHNETIUM-99M–LABELED RADIOPHARMACEUTICALS 7
SINGLE-PHOTON RADIOPHARMACEUTICALS OTHER THAN TC-99M 8
DUAL PHOTON RADIOPHARMACEUTICALS FOR POSITRON EMISSION TOMOGRAPHY 9
DISPENSING RADIOPHARMACEUTICALS 10
RADIATION ACCIDENTS (SPILLS) 12
QUALITY CONTROL IN THE NUCLEAR PHARMACY 13
RECEIVING RADIOACTIVE PACKAGES 13
RADIATION DOSIMETRY 14
Suggested Reading 15
Chapter 2 Molecular Imaging 16
IMAGING TECHNIQUES 16
BIOMARKERS 18
REPORTER GENE IMAGING AND GENE THERAPY 22
IMAGING BIOMARKERS AND NEW DRUG DEVELOPMENT 23
Suggested Reading 23
Chapter 3 Physics of Nuclear Medicine 24
ATOMIC STRUCTURE OF MATTER 24
ELECTROMAGNETIC RADIATION 24
RADIOACTIVITY AND RADIOACTIVE DECAY 26
INTERACTIONS BETWEEN RADIATION AND MATTER 31
Suggested Reading 36
Chapter 4 Radiation Detection and Instrumentation 37
CHARATERISTICS OF A RADIATION DETECTOR 37
TYPES OF RADIATION DETECTORS 38
ANCILLARY EQUIPMENT 40
NUCLEAR MEDICINE IMAGING 41
SUMMARY 50
Suggested Reading 50
Chapter 5 Single-Photon Emission Computed Tomography, Positron Emission Tomography, and Hybrid Imaging\b 51
IMAGE RECONSTRUCTION 51
SINGLE-PHOTON EMISSION COMPUTED TOMOGRAPHY 56
POSITRON EMISSION TOMOGRAPHY 61
Suggested Reading 65
Part II Clinical Nuclear Medicine 66
Chapter 6 Endocrine System 66
THYROID SCINTIGRAPHY AND UPTAKE STUDIES 66
PARATHYROID SCINTIGRAPHY 90
Suggested Reading 97
Chapter 7 Skeletal Scintigraphy\b 98
BONE SCAN 98
CLINICAL USES OF SKELETAL SCINTIGRAPHY 103
BONE INFARCTION AND OSTEONECROSIS 121
OSTEOMYELITIS 123
FLOURINE-18 SODIUM FLUORIDE POSITRON EMISSION TOMOGRAPHY 126
BONE MINERAL MEASUREMENT 128
Suggested Reading 130
Chapter 8 Hepatobiliary System 131
CHOLESCINTIGRAPHY 131
TECHNETIUM-99M RED BLOOD CELL LIVER SCINTIGRAPHY 156
TECHNETIUM-99M SULFUR COLLOID LIVER AND SPLEEN IMAGING 161
SPLEEN SCINTIGRAPHY 163
TECHNETIUM-99M MACROAGGREGATED ALBUMIN HEPATIC ARTERIAL PERFUSION SCINTIGRAPHY 164
Suggested Reading 167
Chapter 9 Genitourinary System 168
RENAL ANATOMY AND FUNCTION 168
RENAL RADIOPHARMACEUTICALS 170
DYNAMIC RENAL IMAGING TECHNIQUES 175
MEASURING RENAL FUNCTION: EFFECTIVE RENAL PLASMA FLOW AND GOMERULAR FILTRATION RATE 191
RENAL CORTICAL IMAGING 194
RADIONUCLIDE CYSTOGRAPHY 201
Suggested Readings 203
Chapter 10 Pulmonary System 204
PULMONARY EMBOLISM 204
VENTILATION PERFUSION SCINTIGRAPHY 205
RADIOPHARMACEUTICALS 206
IMAGE INTERPRETATION 209
VENTILATION-PERFUSION INTERPRETATION CRITERIA 216
OTHER ADDITIONAL V/Q INTERPRETATION CRITERIA 224
OTHER APPLICATIONS OF VENTILATION-PERFUSION SCINTIGRAPHY 224
Suggested Reading 226
Chapter 11 Oncology: Positron Emission Tomography 227
BACKGROUND 227
IMAGE INTERPRETATION 230
CLINICAL USES OF POSITRON EMISSION TOMOGRAPHY IN ONCOLOGY 241
Suggested Reading 264
Chapter 12 Oncology: Non–Positron Emission Tomography 265
PEPTIDE RECEPTOR IMAGING 265
ADRENAL SCINTIGRAPHY 269
MONOCLONAL ANTIBODY IMAGING AND THERAPY 271
NONSPECIFIC BINDING TUMOR AGENTS 278
LYMPHOSCINTIGRAPHY: THE SENTINEL LYMPH NODE 281
INTRAARTERIAL RADIOACTIVE MICROSPHERES 283
BONE PAIN PALLIATION 285
Suggested Reading 287
Chapter 13 Gastrointestinal System 288
ESOPHAGEAL MOTILITY 288
GASTROESOPHAGEAL REFLUX DISEASE 290
GASTRIC MOTILITY SCINTIGRAPHY 294
INTESTINAL TRANSIT SCINTIGRAPHY 305
PROTEIN-LOSING ENTEROPATHY 306
HELICOBACTER PYLORI INFECTION 306
GASTROINTESTINAL BLEEDING 307
HETEROTOPIC GASTRIC MUCOSA 314
PERITONEAL SCINTIGRAPHY 320
Suggested Reading 321
Chapter 14 Infection and Inflammation 322
PATHOPHYSIOLOGY OF INFLAMMATION AND INFECTION 322
RADIOPHARMACEUTICALS 322
CLINICAL APPLICATIONS FOR INFECTION SCINTIGRAPHY 333
Suggested Reading 349
Chapter 15 Central Nervous System 350
CEREBRAL ANATOMY 350
MOVEMENT DISORDERS 368
AMYLOID IMAGING 370
CISTERNOGRAPHY 371
Suggested Reading 377
Chapter 16 Cardiac System 378
MYOCARDIAL PERFUSION SCINTIGRAPHY 378
POSITRON EMISSION TOMOGRAPHY OF THE HEART 407
RADIONUCLIDE VENTRICULOGRAPHY 413
MYOCARDIAL INFARCT AND AMYLOIDOSIS IMAGING 421
Suggested Reading 423
Chapter 17 Pearls, Pitfalls, and Frequently Asked Questions 424
RADIOPHARMACEUTICALS 424
NUCLEAR MEDICINE PHYSICS 425
RADIATION DETECTION AND INSTRUMENTATION 426
SINGLE-PHOTON EMISSION COMPUTED TOMOGRAPHY AND POSITRON EMISSION TOMOGRAPHY 426
ENDOCRINE 427
BONE 429
HEPATOBILIARY 430
GENITOURINARY 432
ONCOLOGY: POSITRON RADIOPHARMACEUTICALS 432
ONCOLOGY: SINGLE-PHOTON RADIOPHARMACEUTICALS 433
GASTROINTESTINAL 434
INFECTION AND INFLAMMATION 435
CENTRAL NERVOUS SYSTEM 436
CARDIAC 437
PULMONARY 438
Index 441