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Llama and Alpaca Care - E-Book

Llama and Alpaca Care - E-Book

Chris Cebra | David E. Anderson | Ahmed Tibary | Robert J. Van Saun | LaRue Willard Johnson

(2014)

Additional Information

Abstract

Designed for the mixed practice large animal veterinarian, veterinary students, and camelid caretakers alike, Llama and Alpaca Care covers all major body systems, herd health, physical examination, nutrition, reproduction, surgery, anesthesia, and multisystem diseases of llamas and alpacas. Written by world-renowned camelid specialists and experts in the field, this comprehensive and uniquely global text offers quick access to the most current knowledge in this area. With coverage ranging from basic maintenance such as restraint and handling to more complex topics including anesthesia and surgery, this text provides the full range of knowledge required for the management of llamas and alpacas.

"..an essential text for anyone working with South American camelids." Reviewed by Claire E. Whitehead on behalf of Veterinary Record, July 2015

  • Over 500 full-color images provide detailed, highly illustrated coverage of all major body systems, physical examination, nutrition, anesthesia, fluid therapy, multisystem diseases, and surgical disorders.
  • World-renowned camelid experts and specialists in the field each bring a specific area of expertise for a uniquely global text.
  • Comprehensive herd health content includes handling techniques, vaccinations, biosecurity, and protecting the herd from predators.
  • Coverage of anesthesia and analgesia includes the latest information on pharmacokinetics of anesthetic drugs, chemical restraint, injectable and inhalation anesthesia, neuroanesthesia, and pain management.
  • Reproduction section contains information on breeding management, lactation, infertility, and embryo transfer.
  • Nutrition information offers detailed nutritional requirements and discusses feeding management systems and feeding behavior.

Table of Contents

Section Title Page Action Price
Front Cover cover
Endsheet 4 IFC1
Llama and Alpaca Care i
Copyright Page ii
Dedication iii
Preface iv
Why Is This Book Important? iv
Organization iv
Acknowledgments iv
Contributors vi
Table Of Contents x
1 Herd Health 1
1 Biosecurity 1
General Principles 1
External Biosecurity 1
Biocontainment 2
Host Animal Risk Factors 2
Infectious Agent Risk Factors 3
Environmental Risk Factors 4
General Cleaning and Disinfection 4
References 5
2 Protection of Camelids from Predators 5
Domestic Dogs 6
Coyotes 6
Mountain Lions 6
Lesser Predators 6
Regulatory Impacts 6
Protective Principles 7
Guardian Dogs 7
Donkeys 7
Llamas 7
Exclusion 8
Fencing 8
Night Penning 8
Startle Schemes 8
Other Methods 8
Supplemental References 8
3 Camelid Vaccinations 9
Bacterial Diseases 9
Clostridial Complex 9
Seven-and Eight-Way Clostridial Vaccines 9
Anthrax 9
Leptospirosis 9
Viral Diseases 9
Rabies 9
West Nile Virus 10
Eastern Equine Encephalitis 10
Equine Rhinopneumonitis 10
Bovine Viral Diarrhea Virus 10
Rotaviruses or Coronaviruses 10
References 10
4 Camelid Herd Health and Nutrition 11
Purpose of Animals 11
Size and Makeup of the Herd 11
Natural Feeding Options 11
Geographic Influences 11
Facility Design for Feeding 11
Feed Procurement and Storage 12
Economic Considerations 12
Conclusion 12
5 Endoparasite Control 12
Anthelmintic Options 13
Gastrointestinal Nematode Control Options 15
References 16
6 Anthelmintic Resistance in Camelid Parasites 16
Definition of Anthelmintic Resistance 16
Multianthelmintic-Resistant Parasites 17
Making the Case for Selective Anthelmintic Treatment 17
Assessing Anthelmintic Efficacy 18
Anthelmintic Use for Control of Haemonchus contortus 20
Ways to Prevent Resistance 20
Biosecurity 21
References 21
7 Camelid Management, Handling Techniques and Facilities, and Herd Management 22
Herd Management 22
Containment versus Restraint 22
Chuting the Camelid 23
The Mini-Catch Pen 24
The Neck Wrap: Putting It on and Taking It off 24
Trimming Toenails or Teaching the Camelid NOT to Pick up Its Feet 25
Picking up a Front Leg 29
Medical Herd Management 30
The Medical Team 30
Injections: A New Way 31
Get Organized 31
Ideal Sites for No-Restraint Injections 32
Subcutaneous Injections 32
Intramuscular Injections 33
Some Suggestions for Giving Injections 33
Alternative Injection Strategies 34
Injections for Crias and Weanlings 34
Drawing Blood 34
Rectal Examinations and Ultrasonography 36
Working the Tail 36
String of Pearls. 36
Transabdominal Ultrasonography Examinations 36
Physical Examinations 37
Head Treatments and Giving Oral Medication 37
Oral Medication 37
Eye Medication 38
Dental Application 38
Fighting Teeth. 38
Trimming Incisors. 38
Microchipping. 38
Emergencies 39
Animals Getting Cast, Tangled, or Stuck 39
Animals Getting Loose 39
Serious Fight between Males 39
TTouch the Ears 39
Chemical Help 39
Final Thoughts on Medical Management 40
Halter Fit 40
The Problem 40
Halters That Are Scary 41
Why Halters Are Uncomfortable 41
Fitting a Halter: A Step-by-Step Process 42
Panels Work! 42
The Perfect Panel 43
The Catch Pen 43
Handling Facilities 44
Teaching Llamas and Alpacas to Lead 44
Special Situations 45
Understanding Male Camelid Behavior 46
It Is Not Always About Dominance 46
Pen Size and Composition 47
Why Can’t We All Just Get Along? 47
If I Could Talk Like the Animals 47
Berserk Male Syndrome or Novice Handler Syndrome? 48
Aggression: More Questions Than Answers 48
Novice Handler Syndrome. 48
How It Starts: Nancy Novice. 49
What Now? 49
Insist on Respectful Behavior. 50
Avoid the Dangers of Overcompensation. 50
Dangerously Aggressive Animals 50
Supplemental Readings 50
2 Nutrition 51
8 Applied Digestive Anatomy and Feeding Behavior 51
Applied Anatomy and Function 51
Forestomach Anatomy 51
Fermentation and Forestomach Microbes 51
Consumption, Digestibility, and Feeding Behavior 51
Food Retention Time 51
Consumption 52
Digestibility 53
Feed Selectivity 53
Diet Composition 53
Implications of Camelid Nutritional Adaptations 54
Microbial Fermentation 54
Metabolic Adaptations 55
Dry Matter Intake 55
References 57
9 Nutritional Requirements 59
Water 59
Water Requirements 60
Water Quality Assessment 62
Energy 64
Energy Partitioning 64
Dietary Energy Sources 65
Carbohydrates 65
Fats 66
Protein 66
Requirement Models 66
Maintenance and Activity 66
Growth 68
Pregnancy 68
Lactation 68
Fiber 69
Protein 69
Protein Systems and Terminology 70
Requirement Models 70
Maintenance 70
Growth 71
Pregnancy 71
Lactation 71
Fiber 71
Minerals 71
Requirement Modeling 72
Macromineral Requirements 72
Calcium and Phosphorus 72
Magnesium 73
Potassium 74
Sodium and Chloride 74
Sulfur 74
Micromineral Requirements 74
Cobalt 74
Copper 74
Iodine 75
Iron 75
Manganese 75
Selenium 76
Zinc 76
Mineral Sources and Feeding 76
Vitamins 77
Water-Soluble Vitamins 77
Fat-Soluble Vitamins 77
Requirement Models 77
Vitamin A 77
Vitamin D 78
Vitamin E 78
Modifiers of Nutrient Requirements 78
References 78
10 Feeds for Camelids 80
Forages and Browse 80
Grasses 80
Legumes 86
Forbs and Browse 86
Sedges and Rushes 86
Supplements and Additives 87
Supplement Ingredients 88
Energy Concentrates 88
Protein Ingredients 88
Mineral and Vitamin Ingredients 88
Additive Ingredients 88
Commercial Supplements 89
Concentrate Products 89
Mineral and Vitamin Supplements 90
References 90
11 Feeding Management Systems 91
Agroecosystems for South American Camelid Production 91
Population, Geographic Area of Breeding, and Farming Systems 91
Characteristics of Breeding 91
Climate 92
Nutritional Critical Periods: Availability and Nutritional Quality 92
Feeding Strategies 93
Feeding Management in Intensive Systems 93
Feeding Programs 95
Feeding the Maintenance Animal 95
Feeding the Pregnant Female 96
Feeding the Lactating Female 97
Feeding the Growing Cria 97
Colostrum Feeding. 97
Milk Feeding and Transition. 97
Postweaning. 98
Feeding Geriatric Animals 99
References 99
12 Nutritional Assessment 100
Nutrient Composition Analysis 100
Feed Sampling Procedures 100
Analytical Procedures 102
Dry Matter 103
Crude Protein 103
Unavailable Protein. 104
Soluble Protein. 104
Degradable Protein. 104
Fiber 104
Energy 105
Nonfiber Carbohydrate Fractions 105
Ether Extract 106
Minerals 106
Dietary and Feeding Management Assessment 106
Dietary Evaluation 107
Feeding System Evaluation 107
Supplement Evaluation 109
Feed Tag Information 109
Nutrient Composition Adequacy 111
Animal Evaluations 112
Body Condition Score 112
Blood Metabolite Analysis 112
Metabolic Indicators 113
Other Analytes 113
Mineral and Vitamin Status Assessment 114
Macrominerals 115
Trace Minerals 115
Fat-Soluble Vitamins 117
Vitamin A. 118
Vitamin D. 119
Vitamin E. 120
Water-Soluble Vitamins 121
Growth Curve Analysis 121
References 122
13 Nutritional Diseases 124
Macronutrient Diseases 124
Protein Energy Malnutrition 124
Epidemiology 124
Clinical Findings 124
Diagnosis and Treatment 124
Prevention 125
Obesity 125
Epidemiology 125
Diagnosis 126
Treatment and Prevention 126
Protein Excess 126
Epidemiology 126
Clinical Presentation 126
Diagnosis and Treatment 126
3 Reproduction 140
14 Anatomy and Physiology of Reproduction in the Female Llama and Alpaca 140
Female Reproductive Anatomy 140
Female Reproductive Physiology 141
Puberty 141
Seasonality 142
Ovarian Activity 142
Copulation and Mating Behavior 143
Ovulation 144
Corpus Luteum Formation and Function 145
Luteolysis 145
Maternal Recognition of Pregnancy 147
Gestation 147
Early Embryo Development 147
Endocrinology of Gestation 147
Placenta 147
Parturition 148
Early Postpartum Period 149
References 149
15 Reproductive Anatomy and Physiology in the Male 150
Anatomy of the Male Reproductive Organs 150
Growth of the Testicle 151
Puberty 151
Endocrine Function of the Testicle 152
Detachment of the Penis–Prepuce Adhesion 152
Mating Behavior and Copulation 153
Site of Ejaculation 155
Sperm Transport within the Female’s Reproductive Tract 155
Sperm Production and Semen Characteristics 155
Factors Affecting Semen Characteristics 156
Effect of Duration of Copulation 156
Effect of Successive Ejaculations 156
Individual Male Effect 156
Effect of Age 157
Effect of Season 157
Semen Biochemistry and Enzymatic Liquefaction 159
Sperm Reserves and Effect of Semen Quality on Fertility 160
References 160
16 Breeding Management 162
Male Selection and Breeding Management 162
Testing of Female Behavior 162
Breeding Systems 164
In-Hand Mating 164
Pen Mating 166
Paddock or Pasture Mating 166
Multiple-Sire Mating 166
Pregnancy Diagnosis 166
Postpartum Breeding 167
References 167
17 Clinical Examination of the Female Reproductive Function 168
History 168
Age 168
Type of Management 168
Evaluation of Breeding Records 169
Evaluation of Sexual Behavior 169
Examination of the Vulva and Perineum 169
Examination of the Udder 170
Transrectal Palpation of the Nonpregnant Female 171
Transrectal Ultrasonography of the Genital Tract 172
Examination Technique 173
Evaluation of the Vestibular Sphincter, Bladder, and Vagina 173
Evaluation of the Cervix 174
Evaluation of the Uterus 174
Evaluation of Ovaries 176
Vaginal Examination 179
Uterine Culture 180
Uterine Cytology 180
Uterine Biopsy 181
Hysteroscopy 183
Laparoscopy 185
Radiography 185
Hormonal Evaluation of Reproductive Function in the Female 186
Ancillary Diagnostics 187
Cytogenetics 187
Follicle-Stimulating Hormone Stimulation Test 187
Evaluation of Trace Minerals and Vitamins 187
References 187
18 Breeding Soundness Examination of the Llama and Alpaca 188
Physical Examination 188
Examination of External Genitalia 188
Scrotum 188
Testes 188
Penis and Prepuce 189
Examination of Internal Genitalia 190
Semen Collection and Evaluation 191
Behavior 191
Semen Collection after Mating 191
Artificial Vagina 191
Electroejaculation 191
Semen Parameters 191
Other Ancillary Tests 193
References 193
19 Infertility and Subfertility in the Male 194
Assessment of Male Fertility 194
History and Initial Clinical Evaluation 194
Evaluation of Infertility or Subfertility 195
Testicular Biopsy 195
Poor Libido 196
Erection Failure 197
Ejaculation Failure 198
Azoospermia and Oligozoospermia 199
Trace Mineral Deficiency 199
Heat Stress 200
Case Management 200
Teratozoospermia 200
Physical Problems as a Source of Infertility or Subfertility 202
Disorders of the Prepuce 202
Preputial Attachment of the Penis 202
Prolapse of the Prepuce 203
Trauma and Posthitis 203
Edema of the Prepuce 203
Disorders of the Penis 203
Prolapse of the Penis (Paraphimosis) 204
Trauma: Balanitis, Abrasions, Ulcerations, and Hair Rings 205
Penile Warts 205
Rupture of Urethra and Urolithiasis 205
Urethritis 205
Hypospadias 206
Disorders of the Testes 206
Cryptorchidism 206
Testicular Hypoplasia 207
Testicular Cysts 208
Ectopic Testes 208
Hydrocele 208
Testicular Degeneration 209
Orchitis 210
Testicular Neoplasia 212
Epididymal Abnormalities 212
Disorders of the Accessory Sex Glands 214
Unexplained Infertility or Subfertility in the Male 214
References 215
20 Infertility and Subfertility in the Female Camelid 216
Common Presenting Complaints 216
General Approach to Diagnosis of Infertility in the Female Camelid 217
Repeat Breeding Syndrome 217
Early Embryonic Death 217
Specific Disorders of the Reproductive System in the Female 218
Ovarian Disorders 218
Congenital Abnormalities of the Ovary 219
Acquired Ovarian Disorders 221
Cystic Conditions of the Ovary 221
Ovarian Inactivity 221
Ovulation Failure 221
Persistent Luteal Activity 222
Luteal Insufficiency 222
Ovarian Neoplasia 222
Other Ovarian and Ovariobursal Diseases 222
Uterotubal Diseases 224
Disorders of the Uterus 225
Congenital Disorders of the Uterus 225
Endometritis and Metritis 225
Predisposing Factors and Etiopathogenesis 226
Diagnosis 227
Therapeutic Approach and Prevention 228
Pyometra and Mucometra 229
Other Uterine Pathologies 230
Diseases of the Cervix 231
Diseases of the Vagina and Vulva 231
References 242
21 Cytogenetics and Infertility 243
Alpaca, Llama, and Camel Chromosomes 243
The Species 243
Chromosome Number and Karyotypes 243
Chromosome Measurements 244
Banding Techniques Applied to Study Camelid Chromosomes 244
GTG-Banding 244
C-Banding 244
Nucleolus-Organizing Regions 244
Other Banding Methods 244
Chromosome Nomenclature 245
Molecular Cytogenetics 246
Clinical Cytogenetics 247
Clinical Karyotyping 247
Numeric Chromosome Abnormalities 247
Structural Chromosomal Abnormalities 247
Sex Chromosome Chimerism 248
Sex Reversal Syndrome 248
Acknowledgments 248
References 249
22 Diagnosis of Pregnancy and Evaluation of High-Risk Pregnancy 250
Diagnosis of Pregnancy 250
Sexual Behavior 250
Progesterone 250
Estrone Sulfate 251
Relaxin 251
Palpation per Rectum 251
Ultrasonography 251
High-Risk Pregnancy and Evaluation of Fetal Well-Being 252
Clinical Evaluation of the Dam 254
Palpation per Rectum 254
Vaginal Examination 254
Endocrinologic Evaluation 254
Ultrasonography 254
Twin Pregnancy 255
References 255
23 Disorders and Diseases of Pregnancy 256
Pregnancy Loss 256
General Approach to Diagnosis of Pregnancy Loss or Abortion 257
Etiology 258
Infectious Causes of Pregnancy Loss 259
Viral Causes of Abortion 259
Bacterial Causes of Abortion 260
Protozoal Causes of Abortion 261
Noninfectious Causes of Pregnancy Loss 262
Iatrogenic Causes of Abortion 262
Nutritional Causes of Abortion 262
Maternal Causes of Noninfectious Abortion 262
Fetal and Placental Noninfectious Causes of Abortion 263
Prevention of Abortion 265
Placentitis 265
Ketosis 266
Vaginal Prolapse 267
Uterine Torsion 269
Prolonged Pregnancy 272
Other Conditions of Pregnancy 272
References 272
24 Parturition and Obstetrics 274
Normal Parturition (Eutocia) 274
Pregnancy Length and Premonitory Signs of Parturition 274
Stages of Parturition 274
Induction of Parturition 276
Incidence and Causes of Dystocia 276
Approach to Dystocia in Camelids 277
Clinical Evaluation of the Dam 277
Determination of Fetal Position and Viability 278
Obstetric Manipulations 278
Assisted Vaginal Delivery 279
Controlled Vaginal Delivery 279
Fetotomy 279
Hysterotomy or Cesarean Section 279
Correction of Specific Common Obstetric Situations 279
Dystocia of Maternal Origin 279
Insufficient Vulvar or Vestibular–Vaginal Dilation 279
Uterine Torsion 280
Uterine Inertia 281
Failure of Cervical Dilation 281
Dystocia of Fetal Origin 281
Incomplete Elbow Extension 281
Foot Nape Posture 281
Head and Neck Deviations 281
Carpal and Shoulder (Forelimb) Flexion 282
Hock Flexion 283
Bilateral Hip Flexion (Breech Presentation) 283
Fetomaternal Disproportion (Fetal Oversize) 285
Twins 285
Fetal Abnormalities 285
Medical Management after Dystocia 285
References 285
25 Lactation and Neonatal Care 286
Prenatal Care 286
Postnatal Care 286
Normal Behavior of the Newborn Cria 287
Evaluation of Passive Transfer of Immunity 288
Prophylactic Treatments of the Newborn 289
Identification of High-Risk Neonates 289
Emergencies in First 24 Hours of Life 289
Failure of Passive Transfer (FPT) 290
Orphaned Crias 291
Congenital Abnormalities 291
Maxillofacial Abnormalities 291
Gastrointestinal and Abdominal Abnormalities 292
Cardiac Abnormalities 292
Skeletal Defects 293
Defects of the Urogenital System 293
Abnormalities of Sensory Organs 293
Meconium Impaction 293
Urine Retention 294
Umbilical Abnormalities 294
Exposure 294
Lactation 295
Anatomy of the Mammary Gland 295
Development of the Mammary Gland 295
Lactation and Properties of Milk 295
References 296
26 Postpartum Disorders 297
Examination of the Postparturient Female 298
Examination of the Placenta 299
Retained Fetal Membranes (Retained Placenta) 300
Postpartum Hemorrhage 302
Cervical Laceration 302
Vaginal Laceration 303
Uterine Tear 304
Rectovaginal Tears or Laceration of the Perineal Body 304
Necrotic Vaginitis and Vaginal Adhesions 304
Vaginal, Vulvar, and Perineal Bruising 305
Uterine Prolapse 305
Vaginal Prolapse 306
Postpartum Metritis 306
Postpartum Downer Syndrome 308
Agalactia 308
Mastitis 309
References 309
27 Artificial Insemination of Llamas and Alpacas 310
Semen Collection and Initial Preparation for Dilution 310
Extenders and Semen Dilution 310
Semen Cryopreservation 310
Freezing and Thawing 311
Artificial Insemination 311
References 314
28 Embryo Transfer 315
History 315
Donor and Recipient Selection 316
Donor Selection 316
Recipient Selection 316
Breeding Management and Timing of Embryo Collection in Non–superstimulated Donors 317
Embryo Collection Technique 317
Evaluation of Embryos 318
Embryo Transfer 318
Ovarian Superstimulation 319
Control of Follicular Dynamics before Superstimulation 320
Ovarian Superstimulation 320
Interspecies Embryo Transfer in South American Camelids 321
References 321
29 Embryo Preservation and in Vitro Production of Embryos 322
In Vitro Embryo Production 323
Postmortem Oocyte Collection 323
In Vivo Collection of Oocytes 323
Ovarian Stimulation 323
Oocyte Recovery 323
In Vivo Oocyte Maturation 323
Embryo in Vitro Production Techniques 323
Nuclear Transfer 324
In Vitro Culture of Embryos 324
Semen Preparation 325
Semen Characteristics 325
Separation of Spermatozoa from Seminal Plasma 325
Selection of Motile Spermatozoa 325
Embryo Preservation 326
Acknowledgments 326
References 326
4 Principles of Health Care 328
30 Physical Examination and Conformation 328
Evaluation of Management and Environmental Factors 328
Observation and Inspection of the Patient 328
Soundness 330
Close Physical Examination 330
Rectal Temperature 330
Peripheral Pulse 330
Respiratory Rate or Character 330
Body Condition Score 331
Visible Mucous Membranes 331
Appearance of Feces 331
Condition of Wool 331
Assessment of Skin 331
Eyes 332
Ears 332
Nares 332
Jaw Alignment and Teeth 332
Lymph Nodes 333
Gender Emphasis 333
Auscultation Procedures 333
Special Examinations 333
Rectal Examination 333
Oral Cavity 334
Musculoskeletal and Nervous Systems 334
Urinary Tract 334
Reproductive Tract 334
Urine Collection 335
Obtaining Peripheral Blood 335
Lymph Node Biopsy 336
The Neonate 336
Conformation 336
Supplemental Reading 337
31 Clinical Pathology 338
Hematology 338
Erythrocytes 338
Normal Red Blood Cell Parameters 338
Anemia 338
Leukocytes 340
Platelets 341
Hemostasis 341
Blood Biochemical Analysis and Interpretation 341
What Constitutes the Ideal Panel? 341
Electrolytes 341
Acid–Base Disturbances 342
Nitrogen Compounds 343
Energy Substrates 344
Proteins 345
Liver, Muscle, and Pancreatic Enzymes 346
Bile Acids and Bilirubin 347
Minerals 347
Analysis of Body Fluids 347
Peritoneal Fluid 347
Pleural Fluid 348
Tracheal Aspirates 348
Cerebrospinal Fluid 348
Joint Fluid 348
References 348
32 Fluid Therapy 350
Indications 350
Assessment 351
Routes 351
Oral Fluids and Orogastric Intubation 351
Intravenous Catheterization 352
Intravenous Fluids 355
Colloids 356
Reference 356
33 Nutritional Support 357
Role of Supportive Nutrition in Disease 357
Characterizing the Hypermetabolic State 357
Consequences of Hypermetabolism 357
Clinical Assessment for Nutritional Support 358
History and Signalment of Problem 358
Determination of Intake Ability 358
Estimation of Digestion or Absorption Ability 359
Nutritional Status 359
Enteral Nutritional Support 359
Rationale for Use 359
Appetite Stimulation 359
Transfaunation 360
Supplementation Methods 360
Nutrient Sources 360
Parenteral Nutritional Support 361
Rationale for Use 361
Formulation Methodology 361
Application Methods 362
Fluid Preparation 362
Administration 362
Monitoring 364
References 364
34 Drug Therapy in Llamas and Alpacas 365
Framework for Evaluating Evidence about Drugs and Drug Selection 365
Features Affecting Drug Selection and Use 365
Anatomy and Physiology 365
Clinical Setting 366
Review of the Principles of Drug Selection 367
Principles of Reviewing for Evidence 367
Principles of Extrapolating 368
Principles of Antimicrobial Drug Therapy 368
Amount of Drug Necessary to Inhibit Growth. 368
Dose Regimen. 369
Reported Clinical Success with the Regimen. 369
Reported or Clinical Experience with Adverse Effects. 369
Collation of Published Evidence on Pharmacotherapeutics in Llamas and Alpacas 369
Evidence Level 1 369
Evidence Level 2 369
Evidence Level 3 369
Evidence Level 4 369
Evidence Level 5 375
Evidence Level 6 375
Summary of Published Evidence 376
The Future of Drug Therapy 376
References 376
5 Medical Disorders 379
35 Disorders of the Skin 379
Normal Hair and Skin 379
Skin Disorders 380
Heavily Fleeced Areas 380
Lightly Fleeced Areas 382
Mucocutaneous Junctions 389
Specialized Skin Structures 390
Foot Pad Erosions and Interdigital Disease 391
References 391
36 Diseases of the Cardiovascular and Hemolymphatic Systems 393
The Cardiovascular System 393
Clinical Evaluation 393
Physical Examination 393
Electrocardiography 394
Thoracic Radiology 395
Echocardiography 396
Arterial Blood Gas Analysis 398
Congenital Heart Defects 398
Ventricular Septal Defects 399
Patent Ductus Arteriosus 400
Atrial Septal Defects and Patent Foramen Ovale 400
Congenital Valve Stenosis and Insufficiency 401
Cyanosis-Producing Congenital Heart Defects 401
Vascular Ring Anomalies 403
Other Vascular Defects 405
Acquired Cardiac Diseases 405
Pericardial Disease 405
Endocarditis 405
Valvular Insufficiency 406
Primary Myocardial Diseases 406
Secondary Myocardial Diseases 407
Sarcocystis. 407
Ionophore Toxicosis. 408
Oleander. 408
Other Plant Cardiotoxins. 409
Neoplasia 409
White Muscle Disease 409
The Hemolymphatic System 409
Anemia 409
Bone Marrow Analysis 412
Nitrates, Nitrites, and Cyanide 413
Polycythemia or Erythrocytosis 413
Granulocytic Anaplasmosis 413
Juvenile Llama Immunodeficiency Syndrome 413
Myelodysplasia 414
Malignant Round Cell Tumors, including Lymphoma, Neuroendocrine Tumors, and Myeloid Leukemia 414
Caseous Lymphadenitis and Other Soft Tissue Abscesses 415
Adult Sepsis 416
Bovine Viral Diarrhea Virus Infection 417
References 419
37 Diseases of the Respiratory Tract 421
Anatomy 421
Examination 422
Supplemental Oxygen and Ventilation 423
Diseases of the Respiratory Tract 423
Dorsal Displacement of the Soft Palate (Pharyngeal Collapse) 423
Laryngeal Edema 424
Arytenoid Chondritis and Laryngeal Abscessation 424
Retropharyngeal Lymphadenopathy 424
Nasal Bots 424
Upper Airway Malformations 425
Fungal Rhinitis and Sinusitis 426
Snake Bite 426
Sinusitis 427
Neoplasia 427
Lower Respiratory tract 428
Acute Pneumonia 428
Viral Pneumonia. 428
Bluetongue. 428
Bacterial Pneumonia and Pleuropneumonia. 429
Streptococcal Infections (Alpaca Fever, Preston Disease) 429
Aspiration Pneumonia 430
Pulmonary Edema and Shock Lung 431
Pulmonary Dysmaturity 431
Chronic Pneumonia 431
Tuberculosis and other Mycobacterial Infections 432
Mycotic Pneumonia and Other Disorders 432
Parasitic Pneumonia 433
Neoplasia 434
Reactive Airway Disease 434
Chylothorax 434
Hemothorax and Pneumothorax 434
Diaphragmatic Hernia 434
Diaphragmatic Paralysis 434
Nonseptic Consolidation Associated with Recumbency 435
Changes of Unknown Significance 435
Pulmonary Alveolar Histiocytosis or Lipid Pneumonia 435
References 435
38 Disorders of the Neurologic System and Special Senses 437
The Neurologic Examination 437
Cerebrospinal Fluid Collection 438
Diagnostic Imaging 439
Cerebral Disorders 440
Antiseizure Medications 440
Hydrocephalus and Hydranencephaly 440
Polioencephalomalacia and Other Causes of Cerebral Necrosis 440
Cerebral Edema 441
Toxic Neuropathies and Neurohepatopathies 442
Idiopathic Epilepsy 442
Cranial Trauma and Intracranial Hemorrhage 442
Bacterial Meningitis, Encephalitis, and Myelitis 443
Viral Encephalitis 443
Fungal Meningoencephalitis 447
Focal Bacterial Infection of the Central Nervous System 447
Verminous Encephalitis 448
Tumors 448
Cerebellar Lesions 448
Flaccid Paralysis 450
Other Lesions Causing Predominantly Spinal or Peripheral Signs 451
Parasitic Encephalitis and Myelitis 453
Extradural Mass Lesions 453
Tetany 454
Deafness and Hearing Loss 455
Diseases Primarily Affecting the Eyes 456
Ophthalmic Examination 456
Normal Ocular Anatomy 457
Diseases Primarily Affecting the Eyes 458
References 462
39 Disorders of the Urinary System 464
Congenital Lesions 466
Acquired Urinary Tract Obstruction 468
Cystitis, Urethritis, and Prostatitis 471
Bladder Rupture 471
Renal Hematuria 472
Nephritis 472
Toxic Nephropathy and Acute Renal Failure 473
Postpartum Incontinence 475
Neoplasms 475
References 476
40 Disorders of the Digestive System 477
Anatomy and Physiology 477
Lips, Tongue, and Oral Cavity 477
Dentition 477
Salivary Glands and Saliva 478
Cud-Chewing Behavior 479
Esophagus 479
Gastric Anatomy and Physiology 479
First and Second Compartments 480
Forestomach Motility 481
The Third Compartment 482
Third Compartment Motility 482
Omentum 482
Small Intestine 482
Cecum, Colon, and Rectum 483
Mesentery, Blood Supply, and Innervation 484
Diagnostic Approaches 484
Behavior 484
Physical Examination and Diagnostic Tests 484
Rectal Examination 484
Abdominal Paracentesis 485
Forestomach Fluid Analysis 485
Blood Interpretation 486
Fecal Occult Blood Analysis 486
Radiography 486
Ultrasonography 486
Endoscopy 487
Exploratory or Laparoscopic Surgery 487
Oral Disorders 487
Ulcerative and Proliferative Lip Lesions 487
Fibropapilloma 488
Oral Mucosal Lesions 488
Ptyalism, Pseudoptaylism, and Cud Spilling 488
Malocclusion 489
Jaw Masses 489
Esophageal Disorders 491
Choke 491
Megaesophagus 492
Esophagitis 493
Gastric Disorders 494
Mineralized Gastroliths and Foreign Bodies 494
Grain Overload or Forestomach Acidosis 495
Ulcerative Gastritis 496
First Compartment Ulcers 496
Third Compartment and Duodenal Peptic Ulcers 497
Neoplasia 499
Clostridial Gastroenteritis or Enterotoxemia 499
Gastric Impaction 500
Parasitic Gastroenteritis 501
Strongyles 501
Protozoa 502
Diagnosis of Parasitic Gastroenteritis 505
Treatment 509
Diarrhea 510
Diarrhea in Crias 511
Clinical Syndromes in Camelids of All Ages 511
Acute Diarrhea 512
Bacteria 512
Viruses 513
Rotavirus. 513
Coronavirus. 513
Other Viruses. 513
Parasites 513
Forestomach Acidosis 513
Peritonitis 514
Diagnosis 514
Frequency 515
Treatment 515
Prevention 516
Chronic Diarrhea and Weight Loss 516
Neoplastic Disorders 517
Lymphoma. 517
Squamous Cell Carcinoma. 517
Nonneoplastic Inflammatory Bowel Diseases 518
Paratuberculosis (Johne disease) and Other Chronic Bacterial Disorders. 518
Eosinophilic or Lymphocytic–Plasmocytic Enteritis (Inflammatory Bowel Disease). 519
Idiopathic Muscular Hypertrophy. 520
Internal Parasitism 520
Colic 520
Specific Causes 521
Frequency 524
Diagnosis 524
Clinical Characteristics 524
Rectal Palpation 526
Clinical Pathology 526
Complete Blood Cell Count 526
Acid–Base Balance 526
Electrolytes 526
Other Blood Constituents 527
Abdominal Paracentesis 527
Abdominal Imaging 527
Radiography 527
Ultrasonography 528
Summary 528
Treatment 529
Medical Treatment 529
Surgical Approaches 532
Postoperative Peritonitis 532
Atresia 532
References 533
41 Hepatic, Pancreatic, and Metabolic Disorders 537
Basic Camelid Energy Metabolism 537
Disorders of Carbohydrate Metabolism 539
Stress Hyperglycemia 539
Diabetes Mellitus 539
Hyperosmolar Disorder 539
Hyperadrenocorticism or Glucocorticoid Administration 540
Pancreatic Necrosis 540
Hypoglycemia 540
Monitoring Disorders of Carbohydrate Metabolism 541
Treatment of Disorders of Carbohydrate Metabolism 541
Disorders of Lipid Metabolism 541
Exuberant Lipid Mobilization (Ketosis, Ketonemia, Acetonemia) 541
Hepatic Lipidosis 541
Hyperlipemia 542
Diagnosing and Monitoring Disorders of Lipid Metabolism 543
Treatment for Disorders of Fat Metabolism 543
Metabolic Acidosis 544
Liver Disorders 545
Hepatitis 545
Toxic Hepatopathy 545
Hepatic Necrosis 546
Liver Flukes 546
Lamanema Migration 547
Tapeworms 548
Passive Congestion of the Liver 548
Hepatic Neoplasms 548
Portosystemic Shunt 548
Vitamins and Minerals 549
Pancreatic Disorders 549
Pancreatic Necrosis 549
Pancreatic Atrophy 549
Hyperthermia, Heat Stress, and Heat Stroke 549
Hypothermia 551
References 551
42 Neonatology and Neonatal Disorders 552
The Abnormal Neonate 552
The Critical Cria 555
Blood Evaluation 555
Fluid Therapy 556
Hypothermia 557
Fever and Hyperthermia 557
Sepsis 558
Respiratory Dysfunction 559
Seizures 561
Heart Murmurs and Cardiac Defects 561
Abdominal Pain or Distension 562
Congenital Defects 564
Meconium Impaction 565
Nutritional Problems 565
Umbilical Abscessation 566
Fluid Accumulation in the Peritoneal Cavity 566
Intestinal Obstruction 567
Third Compartment Ulceration 567
Diarrhea and Enteritis 568
Urinary System Abnormalities 569
Congenital Defects 569
Renal Failure 570
Locomotor Disorders 570
Ligament Laxity 571
Flexural Limb Deformities 571
Rickets and Angular Limb Deformities 571
Joint Ill 573
References 573
6 Anesthesia and Analgesia 576
43 Practical Pharmacokinetics of Anesthetic Drugs 576
Physiologic Concepts 576
Pharmacokinetic Parameters and Dosage Regimens 576
Single Intravenous Dose 577
Constant Rate Intravenous Infusions 578
Suggested Readings 579
44 Preprocedure Considerations 579
Preprocedure Considerations 579
Physical Examination 579
Site Selection and Facility Requirements 579
Patient Positioning 580
Endotracheal Intubation 580
Intravenous Catheters Are “Expensive” and Time Consuming: Are They Really Necessary? 582
Fasting before Anesthesia 582
Eye Protection 582
Oxygen Delivery and Muscle and Nerve Protection 582
Why Is Premedication Important? 583
Important Information on Selected Drugs Used in Chemical Restraint and Anesthesia 584
α2-Adrenergic Agonists 584
α2-Adrenergic Agonist Reversal 585
Benzodiazepines 585
Butorphanol 585
Guaifenesin 585
Atropine 586
Ketamine, Telazol, and Thiopental 586
References 586
45 Chemical Restraint of Camelids 587
Ketamine Stun 587
Intravenous Ketamine Stun 588
Intramuscular Ketamine Stun 589
Xylazine 589
Butorphanol 590
Xylazine–Butorphanol 590
Diazepam–Butorphanol 590
Intravenous Xylazine–Ketamine 590
Intramuscular Xylazine–Ketamine 591
Ruminant Telazol–Ketamine–Xylazine (TKX-Ru) 591
References 592
46 Injectable Anesthesia of Camelids 592
Ketamine Stun 593
Intravenous Xylazine–Ketamine 593
Intramuscular Xylazine–Ketamine 593
Butorphanol–Ketamine–Xylazine (BKX) 594
Double Drip 594
Ruminant Triple Drip (GKX-Ru) 594
Ketamine–Diazepam (Ket-Val) 595
References 595
47 Inhalation Anesthesia in South American Camelids 595
Equipment 595
General Anesthesia 596
Intubation 596
Maintenance 597
Monitoring 597
Supportive Therapy 599
Recovery 599
Suggested Readings 600
48 Local and Regional Analgesic Techniques in Camelids 600
Drugs Used for Locoregional Analgesia 601
Adverse Effects 601
Specific Techniques 601
Field Blocks 602
Oral Blocks 602
Cranial Infraorbital Block 602
Mandibular or Alveolar Block 602
Mental Nerve Block 603
Testicular Blocks 603
Interdigital Block and Abaxial Nerve Block 603
Ocular Blocks 603
Paravertebral Blocks 603
Brachial Plexus Block 603
Intercostal Block 604
Specific Nerve Blocks 604
Bier Block 604
Intraarticular Block 604
Epidurals 604
References 606
49 Perioperative Management of Compromised Camelid Patients 607
Preanesthetic Database 607
Anesthetic Equipment 607
Intravenous Access 607
Airway Management 607
Anesthetic Techniques 608
Monitoring during Anesthesia 608
Support during Anesthesia 608
References 609
50 Obstetric Anesthesia in South American Camelids 609
Why Might South American Camelids Require Sedation or Anesthesia for Obstetric Procedures? 609
Cardiovascular Effects of Pregnancy 610
The Respiratory System 610
Uterus 610
Gastrointestinal Tract, Renal, and Hepatic Effects 610
Pharmacokinetics 610
How to Manage Anesthesia for Nonobstetric Reasons in Pregnant Animals 610
Anesthesia for Obstetric Manipulation 610
Epidural Anesthesia 611
Local Anesthetic Options for Cesarean Section 611
General Anesthesia for Cesarean Section 611
Sedation or Premedication 611
Before Induction 611
Anesthetic Induction and Tracheal Intubation 611
Maintenance of Anesthesia 611
Monitoring of Anesthesia 612
Intravenous Fluid Therapy and Analgesia 612
Recovery from Anesthesia 612
References 612
51 Neuroanesthesia for South American Camelids 612
Why Might South American Camelids Require Brain Neuroanesthesia? 612
Neuroanesthesia for the Brain 613
The Monroe-Kellie Doctrine 613
Intracranial Pressure Regulation 613
Why Is Elevated Intracranial Pressure a Problem? 613
Aims of Anesthetic Management 614
How Can We Alleviate Raised Intracranial Pressure? 614
How Should We Manage Anesthesia in South American Camelids with Brain Disease? 615
Preanesthetic Medication 615
Preoxygenation and Endotracheal Intubation 615
Anesthetic Induction 615
Anesthetic Maintenance 616
Breathing System 616
Monitoring of Anesthesia 616
Analgesia 616
Intravenous Fluid Therapy 616
Temperature 617
Recovery from Anesthesia 617
Cerebrospinal Fluid Sampling 617
Magnetic Resonance Imaging 617
Anesthesia for Spinal Surgery 617
Myelography 617
References 617
52 Pain Management in Camelids: 618
Are We Treating Pain? 618
Pain in Mammals 618
Recognition of Pain 618
Economics of Pain Management 618
Lack of Knowledge of Analgesic Drugs and Techniques and Fear of Side Effects 619
Why Should We Treat Pain? 619
Principles of Pain Management 619
Analgesic Drugs and Techniques 619
Nonsteroidal Antiinflammatory Drugs 619
Local Anesthetic Drugs 620
Opioids 620
α2-Agonists 622
Opioid–α2-Agonist Combinations 622
Constant Rate Infusion 622
Opioids 622
Lidocaine 622
Ketamine 623
α2-Agonists 623
Combinations of Opioids, Ketamine, and Lidocaine (and α2-Agonists?) 623
Calculations of Continuous Rate Infusion Dosages 623
Nonpharmacologic Treatment of Pain 623
References 623
53 Constant Rate Infusion Technique for Management of Severe Pain in Camelids 624
Trifusion 625
Trifusion and Pentafusion Continuous Rate Infusion Technique 625
Pentafusion: Development and Use 625
Pentafusion: Equipment Required 626
Pentafusion: Sample Protocol (450-kg Patient) 627
7 Surgical Disorders 649
55 Principles of Surgery 649
Preoperative Considerations 649
Surgical Site Preparation 649
Hair Removal 649
Antiseptics 650
Preparation Time for Patient Asepsis 651
Aseptic Scrubbing Technique 651
Surgeon Preparation 651
Surgical Hand Preparation 651
Gloves 652
Suture Materials: Basic Principles 652
Knot Security of Suture Material 653
References 655
56 Ocular Surgery 657
Conjunctival Rotating Pedicle Flap 657
Enucleation 658
Nasolacrimal Duct Obstruction 659
References 660
57 Gastrointestinal Surgery in Alpacas and Llamas 661
Clinical Signs of Surgical Gastrointestinal Disease 661
Diagnostic Testing 662
Surgical Approaches and Techniques 662
Lateral Abdominal Wall Laparotomy 663
Ventral Midline Laparotomy 663
Forestomach Surgery 664
C1 Fistulation 664
Surgery of the Small Intestine 664
Enterotomy 664
Resection of the Intestine 665
Surgery of the Large Intestine 666
Rectal Tears 667
Torsion of the Spleen 667
Complications 667
Prognosis 667
References 668
58 Musculoskeletal Surgery 669
Musculoskeletal Anatomy 669
Anatomy of the Suspensory Apparatus and Distal Limb 669
Suspensory Ligament 669
Sesamoidean Ligaments 669
Superficial Digital Flexor Tendon 669
Deep Digital Flexor Tendon 670
Lumbricalis Muscle 671
Anatomy of Diarthrodial Joints 671
Carpus 672
Joint Injection Landmarks. 672
Tarsus 672
Joint Injection Landmarks. 673
Metacarpophalangeal or Metatarsophalangeal (Fetlock) Joint 673
Appendices 745
Appendix A 745
Appendix B 747
Appendix C 749
Index 751
A 751
B 754
C 756
D 760
E 762
F 764
G 766
H 767
I 768
J 770
K 770
L 770
M 772
N 775
O 776
P 777
Q 780
R 780
S 781
T 784
U 786
V 788
W 789
X 789
Y 789
Z 789