Menu Expand
Pathology for the Physical Therapist Assistant - E-Book

Pathology for the Physical Therapist Assistant - E-Book

Catherine C. Goodman | Kenda S. Fuller

(2011)

Additional Information

Abstract

No other textbook provides coverage of the essential concepts of disease processes and disorders with the specific needs of the physical therapy assistant in mind. Pathology for the Physical Therapist Assistant provides coverage of disease processes and systemic disorders as well as guidelines, precautions, and contraindications for physical therapy interventions. Catherine Goodman, Kenda Fuller, and Robbie O’Shea share their expertise in a consistent, well-organized approach that defines each disorder, describes the appropriate physical therapy assessment and intervention, and rounds out the discussion with relevant case study examples based on established practice patterns.

  • Chapters follow a consistent organization, first defining a disorder and then describing the appropriate physical therapy assessment and intervention.
  • Full-color art throughout clearly depicts pathologies and interventions.
  • Case studies provide examples of physical therapy applications to help you connect theory and practice and build strong clinical reasoning skills.
  • Special boxes highlight Clinical Signs, Interventions, and Case Studies to alert you to important information within the text.
  • Terminology and language from the Guide to Physical Therapy Practice is used throughout to familiarize you with standardized terminology used in practice.
  • A companion Evolve website provides additional online learning activities including online chapters, references linked to Medline, case studies, and self-test questions.

Table of Contents

Section Title Page Action Price
Front cover cover
Half title page i
Book marketing page ii
Pathology for the Physical Therapist Assistant iii
Copyright page iv
CONTRIBUTORS v
PREFACE vii
ACKNOWLEDGMENTS viii
Table of Contents ix
I Introduction 1
1 Introduction to Concepts of Pathology 1
Pathogenesis of Disease 1
Pathology and the Guide to Physical Therapist Practice 1
Concepts of Health, Illness, and Disability 1
Health 1
Illness 2
Definition 2
Incidence and Prevalence 2
Natural History 2
Acute Illness 3
Chronic Illness 3
Psychologic Aspects 3
Disability 4
Classification Models 4
Nagi Disablement Model. 4
International Classification of Functioning, Disability, and Health. 4
ICF—Language. 5
Cognitive Disability 5
1-1 Special Implications for the PTA 7
Disability Classifications 7
Physical Disability 7
Cognitive Disability 7
Health Promotion and Disease Prevention 7
Health Promotion 8
Disease Prevention 8
1-2 Special Implications for the PTA 8
Health Promotion and Disease Prevention 8
Role in Prevention and Wellness2 9
Genetic Aspects of Disease 9
The Human Genome Project 10
Gene Therapy 10
Uses for Gene Therapy 11
Approaches to Gene Therapy 12
Obstacles to Gene Therapy 13
Gene Doping. 13
Gene Testing 13
1-3 Special Implications for the PTA 13
Genetic Aspects of Disease 13
References 13
References 13.e1
2 Problems Affecting Multiple Systems 14
Systemic Effects of Pathology 14
Systemic Effects of Acute Inflammation 14
Systemic Effects of Chronic Inflammation 14
Systemic Factors Influencing Healing 14
Consequences of Immunodeficiency 14
Systemic Effects of Neoplasm 15
2-1 Special Implications for the PTA 15
Systemic Effects of Pathology22,23 15
Adverse Drug Reactions 15
Definition and Overview 15
Incidence 16
Etiologic and Risk Factors 16
Clinical Manifestations 16
Medical Management 16
2-2 Special Implications for the PTA 17
Adverse Drug Reactions 17
Exercise and Drugs 17
Specific Drug Categories 18
Nonsteroidal Antiinflammatory Drugs 18
2-3 Special Implications for the PTA 19
Nonsteroidal Antiinflammatory Drugs 19
Immunosuppressive Agents 19
2-4 Special Implications for the PTA 19
Immunosuppressants 19
Corticosteroids 19
Adverse Effects of Glucocorticoids 20
Effects on Skin and Connective Tissue. 20
Steroid-Induced Myopathy. 20
Effect of Steroids on Growth. 21
Designer Glucocorticoids 21
Anabolic-Androgenic Steroids 21
2-5 Special Implications for the PTA 22
Corticosteroids 22
Inflammation and Infection 22
Intensive Care Setting 22
Intraarticular Injections 22
Exercise and Steroids 22
Monitoring Vital Signs 23
Steroids, Nutrition, and Stress 23
Psychologic Considerations 23
Anabolic Steroids 23
Radiation Injuries 23
Definition and Overview 23
Etiologic and Risk Factors 24
Pathogenesis 24
Clinical Manifestations and Medical Management 24
Radiation Esophagitis and Enterocolitis 24
Radiation Heart Disease 24
Radiation Lung Disease 24
Radiation Dermatitis 25
Effects of Radiation on Connective Tissue 26
Effects of Radiation on the Nervous System 27
Acute Symptoms. 27
Subacute Symptoms. 27
Delayed Complications. 27
Radionecrosis. 27
Myelopathy. 27
Plexopathy. 27
Pregnancy 27
2-6 Special Implications for the PTA 28
Radiation 28
Radiation Hazard for Health Care Professionals 28
Postradiation Therapy 28
Postradiation Infection 28
Radiation Therapy and Exercise 28
Chemotherapy 29
Characteristics and Categories of Chemotherapeutic Drugs 29
Adverse Effects of Chemotherapy 29
Alopecia 29
Gastrointestinal Toxicity 29
Myelosuppression 29
Fatigue 30
Cardiotoxicity 30
Renal Toxicity 30
Neuropathies 30
Adverse Effects of Stem-Cell Transplantation 30
2-7 Special Implications for the PTA 31
Chemotherapy 31
Late Effects of Chemotherapy 31
Neuropathy 31
Chemotherapy and Exercise 31
Specific Disorders Affecting Multiple Systems 32
Vasculitic Syndromes 32
Rheumatoid Arthritis 32
Systemic Lupus Erythematosus 33
Systemic Sclerosis 33
Tuberculosis 34
Sarcoidosis 34
Multiple Organ Dysfunction Syndrome 34
Overview 34
Definition and Etiologic and Risk Factors 34
Pathogenesis 34
Clinical Manifestations 34
Medical Management 34
Fluid and Electrolyte Imbalances 35
Aging and Fluid and Electrolyte Balance 35
Fluid Imbalances 35
Overview 35
Etiologic Factors and Pathogenesis 35
Clinical Manifestations 36
Medical Management 36
2-8 Special Implications for the PTA 36
Fluid Imbalances 36
Monitoring Fluid Balance 36
Dehydration 37
Skin Care 37
Electrolyte Imbalances 37
Overview 37
Etiologic and Risk Factors 37
Clinical Manifestations 38
Medical Management 38
2-9 Special Implications for the PTA 38
Electrolyte Imbalances 38
Common Causes of Fluid and Electrolyte Imbalances 38
Overview 38
Clinical Manifestations 40
2-10 Special Implications for the PTA 43
Assessment of Fluid and Electrolyte Imbalance 43
Acid-Base Imbalances 43
Overview 43
Incidence 43
Clinical Manifestations 43
Medical Management 43
Diagnosis. 43
Treatment. 43
Respiratory Acidosis 43
II Clinical Medicine 91
4 The Immune System 91
Types of Immunity 91
Innate and Acquired Immunity 91
Acquired Immunity: Active or Passive Immunity 91
The Immune Response 92
Antigens 92
Cell Markers 92
Innate Immunity 92
Exterior Defenses 92
Phagocytes. 93
Inflammatory Mediators 93
Natural Killer Cells 94
Acquired Immunity 94
Humoral Immunity 94
Cell-Mediated Immunity 94
Summary of the Immune Response 94
Aging and the Immune System 96
Changes in Innate Immunity 96
Changes in Acquired Immunity 96
Factors Affecting Immunity 96
Interactions between the Immune and Central Nervous Systems 97
Exercise Immunology 98
Effect on Neutrophils and Macrophages 98
Effect on Natural Killer Cells 98
Effect on Lymphocytes 98
Effect on Cytokines 98
Exercise and Infection 98
4-1 SPECIAL IMPLICATIONS FOR THE PTA 99
Exercise Immunology 99
Immunodeficiency Diseases 99
Primary Immunodeficiency 99
Secondary Immunodeficiency 99
Iatrogenic Immunodeficiency 99
Consequences of Immunodeficiency 100
4-2 SPECIAL IMPLICATIONS FOR THE PTA 100
Infection Control in Immunodeficiency Disorders 100
Acquired Immunodeficiency Syndrome 100
Overview 100
Definition 101
Incidence and Prevalence 101
Etiologic Factors, Transmission, and Risk Factors 101
Pathogenesis 102
Clinical Manifestations 104
Asymptomatic Stage (CD4 Count of 500 Cells/mm3 or More). 104
Early Symptomatic Stage (CD4 Count of 200 to 500 Cells/mm3). 104
HIV Advanced Disease (AIDS; CD4 Count of 200 Cells/mm3 or Less). 104
Pain Syndromes. 104
Medical Management 106
Prevention. 106
Diagnosis. 106
Treatment. 107
Prognosis. 107
4-3 SPECIAL IMPLICATIONS FOR THE PTA 108
Acquired Immune Deficiency Syndrome 108
Preferred Practice Patterns 108
Prevention of Transmission 108
Postexposure Prophylaxis 109
HIV and Rehabilitative Therapy 110
Exercise and HIV/AIDS 111
Early-Stage HIV Disease 111
Advanced Stages or Chronic HIV Disease 111
All Stages 111
Chronic Fatigue and Immune Dysfunction Syndrome 112
Overview 112
Incidence and Risk Factors 112
Etiologic Factors and Pathogenesis 113
Clinical Manifestations 113
Medical Management 113
Diagnosis. 113
Treatment. 114
Prognosis. 114
4-4 SPECIAL IMPLICATIONS FOR THE PTA 114
Chronic Fatigue Syndrome 114
Preferred Practice Patterns 114
Exercise and Chronic Fatigue Syndrome 114
Monitoring Vital Signs 114
Hypersensitivity Disorders 115
Type I Hypersensitivity (Immediate Hypersensitivity, Allergic Disorders, Anaphylaxis) 115
Type II Hypersensitivity (Cytotoxic Reactions to Self-Antigens) 116
Type III Hypersensitivity (Immune Complex Disease) 116
Type IV Hypersensitivity (Cell-Mediated Immunity) 116
4-5 SPECIAL IMPLICATIONS FOR THE PTA 116
Hypersensitivity Disorders 116
Preferred Practice Pattern 116
Autoimmune Diseases 116
Definition and Overview 116
Etiologic and Risk Factors 117
Pathogenesis 117
Clinical Manifestations 117
Medical Management 118
Diagnosis. 118
Treatment. 118
Systemic Lupus Erythematosus 118
Definition and Overview 118
Incidence 118
Etiologic and Risk Factors 118
Pathogenesis 119
Clinical Manifestations 119
Musculoskeletal System. 119
Cutaneous and Membranous Lesions. 119
Cardiopulmonary System. 120
Central Nervous System. 120
Renal System. 120
Other Systems. 120
Medical Management 120
Prevention. 120
Diagnosis. 120
Treatment. 121
Prognosis. 121
4-6 SPECIAL IMPLICATIONS FOR THE PTA 121
Systemic Lupus Erythematosus 121
Preferred Practice Patterns 121
Fibromyalgia 122
Definition and Overview 122
Incidence 122
Risk Factors 122
Etiologic Factors 122
Pathogenesis 122
Hypothalamic-Pituitary-Adrenal Axis. 122
Autonomic Nervous System. 123
The Reproductive Hormone Axis. 123
Immune System. 123
Clinical Manifestations 123
Medical Management 123
Diagnosis. 123
Treatment. 124
Prognosis. 124
4-7 SPECIAL IMPLICATIONS FOR THE PTA 125
Fibromyalgia 125
Preferred Practice Patterns 125
Modalities and Fibromyalgia 126
Exercise and Fibromyalgia 126
References 127
References 127.e1
5 Infectious Disease 128
Signs and Symptoms of Infectious Diseases 129
Aging and Infectious Diseases 130
Infectious Diseases 131
Definition and Overview 131
Types of Organisms 131
The Chain of Transmission 132
Pathogens 133
Reservoir 133
Portal of Exit 133
Mode of Transmission 133
Portal of Entry 134
Host Susceptibility 134
Lines of Defense. 134
Control of Transmission 135
5-1 Special Implications for the PTA 137
Control of Transmission 137
Nosocomial Infections 137
Hydrotherapy and Therapeutic Pool Protocol 138
Home Health Care 138
Diagnosis of Infectious Diseases 139
Specific Infectious Diseases 140
Bacterial Infections 140
Clostridium difficile 140
Overview. 140
Incidence. 140
Etiology, Transmission, and Risk Factors. 140
Pathogenesis. 140
Clinical Manifestations. 140
Medical Management 140
Diagnosis and Treatment. 140
Prevention. 140
Staphylococcal Infections 141
Overview and Incidence. 141
Risk Factors. 141
Pathogenesis. 141
Clinical Manifestations. 141
Medical Management 141
Diagnosis, Treatment, and Prognosis. 141
Streptococcal Infections 141
Group A Streptococci. 141
5-2 Special Implications for the PTA 142
Staphylococcal Infections 142
Preferred Practice Patterns 142
Streptococcal Pharyngitis. 143
Scarlet Fever. 143
Impetigo. 143
Erysipelas. 143
Streptococcal Cellulitis. 144
Streptococcal Necrotizing Fasciitis. 144
Streptococcal Myositis. 144
Puerperal Sepsis. 144
5-3 Special Implications for the PTA 145
Streptococcal Infections 145
Preferred Practice Patterns 145
Group B Streptococci. 145
Streptococcus pneumoniae 145
Etiologic and Risk Factors. 145
Clinical Manifestations. 145
Diagnosis, Treatment, and Prevention. 145
Gas Gangrene (Clostridial Myonecrosis) 146
Definition and Overview. 146
Pathogenesis. 146
Clinical Manifestations. 146
Medical Management 146
Diagnosis, Treatment, and Prognosis. 146
5-4 Special Implications for the PTA 146
Gas Gangrene 146
Preferred Practice Patterns 146
Pseudomonas 146
Overview. 146
Pathogenesis. 147
Clinical Manifestations. 147
Respiratory Tract Infections. 147
Bacteremia. 147
Central Nervous System Infections. 147
Skin and Soft Tissue Infections. 148
Bone and Joint Infections. 148
Other Pseudomonas Infections. 148
Medical Management 148
Diagnosis, Treatment, and Prognosis. 148
5-5 Special Implications for the PTA 148
Pseudomonas Infections 148
Preferred Practice Patterns 148
Viral Infections 149
III Pathology of the Musculoskeletal System 553
13 Introduction to Pathology of the Musculoskeletal System 553
Advances in Musculoskeletal Biotechnology 553
Biologic Response to Trauma 554
13-1 Special Implications for the PTA 555
Biologic Response to Trauma 555
The Musculoskeletal System throughout the Life Span 555
Muscle 555
Sarcopenia 555
Overview and Definition. 555
Etiology. 555
Pathogenesis. 555
Effects of Sarcopenia. 556
Exercise and Sarcopenia. 556
Joint and Connective Tissue 556
Increased Stiffness and Decreased Flexibility 556
Changes in Articular Cartilage 557
Tendons 557
Proprioception 557
Bone 557
The Musculoskeletal System and Exercise 558
Muscle 558
Strength Training 558
Endurance Training 559
Joint 559
Bone 559
Specific Exercise Guidelines 559
Musculoskeletal System Disease 560
Cancer 560
Infection 561
References 561
References 561.e1
14 Genetic and Developmental Disorders 562
Down Syndrome 562
Definition and Incidence 562
Etiologic Factors and Pathogenesis 562
Clinical Manifestations 562
Medical Management 563
Diagnosis. 563
Treatment. 563
Prognosis. 563
14-1 Special Implications for the PTA 564
Down Syndrome 564
Preferred Practice Patterns 564
Precautions 564
Gross and Fine Motor Development 564
Physical Activity and Exercise 564
Scoliosis 564
Definition 564
Overview and Incidence 565
Etiologic Factors 565
Pathogenesis 565
Clinical Manifestations 565
Medical Management 566
Treatment. 566
Prognosis. 567
14-2 Special Implications for the PTA 567
Scoliosis 567
Preferred Practice Patterns 567
Therapeutic Interventions 567
Postoperative 568
Precautions 568
Kyphoscoliosis 568
Overview and Etiologic Factors 568
Clinical Manifestations 569
Medical Management 569
Diagnosis. 569
Treatment. 569
14-3 Special Implications for the PTA 569
Kyphoscoliosis 569
Preferred Practice Patterns 569
Spina Bifida Occulta, Meningocele, Myelomeningocele 569
Definition 569
Incidence and Etiologic Factors 569
Clinical Manifestations 570
Medical Management 573
Diagnosis. 573
Treatment. 574
Prognosis. 576
Prognosis for Motor Function. 576
14-4 Special Implications for the PTA 576
Spina Bifida Occulta, Meningocele, Myelomeningocele 576
Preferred Practice Patterns 576
Neonatal Intensive Care Unit 577
Therapeutic Interventions 577
Skin Care 577
Exercise 577
Shunt Care 577
Tethered Cord 578
Latex Sensitivities 578
Adaptive Equipment 578
Neuromuscular Disorders 578
The Muscular Dystrophies 578
Definition and Overview 578
Incidence and Etiologic Factors 579
Pathogenesis 580
Duchenne’s and Becker’s Muscular Dystrophy. 580
Limb-Girdle Muscular Dystrophy. 580
Congenital Muscular Dystrophy. 581
Facioscapulohumeral Dystrophy. 581
Myotonic Dystrophy. 581
Clinical Manifestations 581
Duchenne’s Muscular Dystrophy. 581
Becker’s Muscular Dystrophy. 583
Limb-Girdle Muscular Dystrophy. 583
Congenital Muscular Dystrophy. 583
Facioscapulohumeral Dystrophy. 583
Myotonic Dystrophy. 584
Medical Management 584
Treatment. 584
Prognosis. 584
14-5 Special Implications for the PTA 584
Muscular Dystrophy 584
Preferred Practice Patterns 584
Precautions 585
Therapy Interventions 585
Spinal Muscular Atrophy 585
Overview and Incidence 585
Etiologic Factors and Pathogenesis 585
Clinical Manifestations 586
Medical Management 586
Diagnosis 586
Treatment 587
Prognosis. 587
14-6 Special Implications for the PTA 587
Spinal Muscular Atrophy 587
Preferred Practice Patterns 587
Precautions 588
Therapy Interventions 588
Torticollis 589
Definition and Overview 589
Incidence and Etiologic Factors 589
Pathogenesis 589
Clinical Manifestations 589
Medical Management 590
Diagnosis. 590
Treatment. 590
Prognosis. 591
14-7 Special Implications for the PTA 592
Torticollis 592
Preferred Practice Patterns 592
Erb’s Palsy 592
Definition and Overview 592
Incidence 592
Etiologic and Risk Factors 592
Clinical Manifestations 592
Medical Management 592
Diagnosis. 592
Treatment. 593
Prognosis. 594
14-8 Special Implications for the PTA 594
Erb’s Palsy 594
Preferred Practice Pattern 594
Osteogenesis Imperfecta 595
Overview and Incidence 595
Etiologic Factors and Pathogenesis 595
Clinical Manifestations 596
Medical Management 597
Diagnosis. 597
Treatment. 597
Prognosis. 597
14-9 Special Implications for the PTA 598
Osteogenesis Imperfecta 598
Preferred Practice Patterns 598
Precautions 598
Family Education 598
Therapy Interventions 598
Mobility 598
Arthrogryposis Multiplex Congenita 599
Definition and Overview 599
Incidence and Etiologic Factors 599
Pathogenesis 599
Clinical Manifestations 599
Medical Management 600
Diagnosis. 600
Treatment and Prognosis. 600
14-10 Special Implications for the PTA 600
Arthrogryposis Multiplex Congenita 600
Preferred Practice Patterns 600
Therapeutic Interventions 600
References 600
References 600.e1
15 Infectious Diseases of the Musculoskeletal System 601
Osteomyelitis 601
Definition 601
Incidence 601
Etiologic Factors 601
Pathogenesis 601
Clinical Manifestations 602
Medical Management 603
Prevention. 603
Diagnosis. 603
Treatment. 604
Prognosis. 604
15-1 Special Implications for the PTA 604
Osteomyelitis 604
Preferred Practice Patterns 604
Preventing Complications 605
Infections of Prostheses and Implants 605
Overview 605
Incidence 605
Risk Factors 605
Etiologic Factors and Pathogenesis 606
Clinical Manifestations 606
Medical Management 606
Prevention. 606
Diagnosis. 606
Treatment. 607
Prognosis. 607
15-2 Special Implications for the PTA 607
Infections of Prostheses and Implants 607
Breast Implantation 607
Diskitis 608
Overview and Incidence 608
Etiologic and Risk Factors 608
Pathogenesis 608
Clinical Manifestations 608
Medical Management 608
Diagnosis. 608
Treatment. 608
Prognosis. 608
15-3 Special Implications for the PTA 609
Diskitis 609
Infectious (Septic) Arthritis 609
Overview and Incidence 609
Etiologic and Risk Factors 609
Pathogenesis 609
Clinical Manifestations 610
Medical Management 610
Diagnosis. 610
Treatment. 610
Prognosis. 610
15-4 Special Implications for the PTA 611
Infectious (Septic) Arthritis 611
Infectious (Inflammatory) Muscle Disease 611
Myositis 611
Overview and Incidence 611
Incidence 611
Etiology and Pathogenesis 611
Clinical Manifestations 611
Medical Management 611
Diagnosis. 611
Treatment and Prognosis. 612
15-5 Special Implications for the PTA 612
Myositis 612
Infections of Bursae and Tendons 612
Overview and Incidence 612
Etiologic and Risk Factors 612
Pathogenesis 612
Clinical Manifestations 612
Medical Management 612
Diagnosis, Treatment, and Prognosis. 612
15-6 Special Implications for the PTA 613
Infections of Bursae and Tendons 613
Extrapulmonary Tuberculosis 613
Skeletal Tuberculosis 613
Overview and Incidence 613
Pathogenesis and Clinical Manifestations 613
Medical Management 613
Diagnosis. 613
Treatment and Prognosis. 613
15-7 Special Implications for the PTA 614
Extrapulmonary and Skeletal Tuberculosis 614
Preferred Practice Patterns 614
Summary of Special Implications for the PTA 615
References 615
References 615.e1
16 Musculoskeletal Neoplasms 616
Primary Tumors 616
Overview 616
Description 616
Benign Neoplasm 616
Malignant Neoplasm 616
Incidence 616
Risk Factors 616
Etiologic Factors and Pathogenesis 617
Bone Tumors. 617
Soft Tissue Tumors. 618
Clinical Manifestations 619
Pain. 619
Fractures. 619
Miscellaneous. 619
Swelling. 619
Mass. 619
Metastases. 619
Medical Management 619
Diagnosis. 619
Physical Examination. 619
Radiographic Examination. 619
Imaging. 620
Biopsy. 620
Laboratory Tests. 621
Staging and Grading. 621
Treatment. 621
Prognosis. 622
Recurrence. 622
16-1 Special Implications for the PTA 622
Primary Tumors 622
Preferred Practice Patterns 622
Screening Assessment 622
Rehabilitation 622
Prescriptive Exercise 623
Primary Benign Bone Tumors 623
Bone Island 623
Overview and Incidence 623
Clinical Manifestations 623
Medical Management 623
16-2 Special Implications for the PTA 623
Bone Islands 623
Osteoid Osteoma 623
Overview, Incidence, and Etiologic Factors 623
Pathogenesis 624
Clinical Manifestations 624
Medical Management 624
Diagnosis. 624
Treatment and Prognosis. 624
Osteoblastoma 624
Overview 624
Incidence 625
Clinical Manifestations 625
Medical Management 625
Diagnosis. 625
Treatment. 625
Prognosis. 625
Primary Malignant Bone Tumors 626
Osteosarcoma 626
Overview 626
Incidence 626
Etiologic and Risk Factors 626
Pathogenesis 626
Clinical Manifestations 626
Medical Management 626
Diagnosis. 626
Treatment. 627
Prognosis. 629
16-3 Special Implications for the PTA 629
Osteosarcoma 629
Postoperative Rehabilitation 629
Chondrosarcoma 631
Overview and Incidence 631
Pathogenesis 631
Clinical Manifestations 631
Medical Management 631
Diagnosis. 631
Treatment. 631
Prognosis. 631
Ewing’s Sarcoma 632
Overview and Incidence 632
Risk Factors, Etiologic Factors, and Pathogenesis 632
Clinical Manifestations 632
Medical Management 632
Diagnosis. 632
Treatment. 633
Prognosis. 633
16-4 Special Implications for the PTA 634
Ewing’s Sarcoma 634
Multiple Myeloma 634
Primary Soft Tissue Tumors 634
Benign Soft Tissue Tumors 634
Malignant Soft Tissue Tumors 635
Overview and Incidence 635
Types of Soft Tissue Sarcomas. 635
Etiology and Risk Factors 636
Pathogenesis 636
Clinical Manifestations 636
Medical Management 636
Diagnosis. 636
Treatment. 636
Prognosis. 636
Cartilaginous Tumors 636
Osteochondroma 637
Overview and Incidence. 637
Pathogenesis. 637
Clinical Manifestations. 637
Medical Management 637
Diagnosis. 637
Treatment and Prognosis. 638
Metastatic Tumors 638
Overview 638
Incidence and Etiology 639
Risk Factors 639
Pathogenesis 639
Clinical Manifestations 639
Medical Management 639
Diagnosis. 639
Treatment. 640
Prognosis. 641
16-5 Special Implications for the PTA 641
Metastatic Tumors 641
Early Detection 641
Preoperative Intervention 641
Rehabilitation 641
References 642
References 642.e1
17 Bone, Joint, and Soft Tissue Diseases and Disorders 643
Bone 643
Bone Composition 643
Bone Remodeling 643
Metabolic Bone Disease 644
Osteoporosis 644
Bone Demineralization. 644
Guide to Physical Therapy Practice Patterns. 645
Definition and Incidence. 645
Risk Factors. 646
Hormonal Status. 647
Heredity/Genetics. 647
Ethnicity. 647
Physical Inactivity. 647
Tobacco and Alcohol. 647
Medications. 647
Depression. 647
Diet and Nutrition. 647
Structures Involved. 647
Signs and Symptoms. 648
Common Tests and Measures. 648
History. 648
Bone Mineral Density Testing. 649
Radiography. 649
Laboratory Testing. 649
Screening. 649
Common Management. 650
Diet. 650
Medications. 650
Rehabilitation. 650
Exercise. 652
Vibration. 652
The Female Athlete. 652
Aquatic Exercise. 653
Surgery. 653
Prognosis. 653
Precautions and Complications. 653
Osteomalacia 653
Guide to Physical Therapy Practice Pattern. 653
Definition and Incidence. 653
Structures Involved. 654
Signs and Symptoms. 654
Common Tests and Measures. 655
Common Management. 655
Paget’s Disease 655
Guide to Physical Therapy Practice Pattern. 655
Definition and Incidence. 656
Structures Involved. 656
Signs and Symptoms. 656
Common Tests and Measures. 659
Common Management. 660
Exercise Programs. 660
Prognosis. 660
Fracture 661
Guide to Physical Therapist Practice Patterns 661
Definition and Incidence 661
Signs and Symptoms 663
Common Tests and Measures 664
Common Management 664
Surgery. 664
General Rehabilitation Principles. 664
Rehabilitation in the Acute Care Setting. 665
Rehabilitation for Vertebral Compression Fractures. 665
Modalities and Fractures. 665
Bone Grafting. 666
Complications. 666
Heterotopic Ossification 666
Guide to Physical Therapy Practice Pattern 666
Definition and Incidence 666
Structures Involved 667
Signs and Symptoms 667
Common Tests and Measures 667
Common Management 668
Prevention. 668
Physical Therapy. 668
Complications. 668
Osteochondroses 668
Osteochondritis Dissecans 669
Guide to Physical Therapist Practice Patterns. 669
IV Pathology of the Nervous System 715
18 Introduction to Central Nervous System Disorders 715
Pathogenesis 715
Cellular Dysfunction 715
Glial Cells 716
Nerve Cells 717
Neurotransmission 719
Amino Acids. 720
Amines. 721
Neuropeptides. 721
Gaseous Neurotransmitters and Others. 721
Clinical Manifestations 722
Sensory Disturbances 722
Brainstem Dysfunction 722
Movement Disorders 724
Disorders of Coordinated Movement 725
Deficits of Higher Brain Function 727
Altered States of Consciousness 729
Memory Problems 730
Autonomic Nervous System 733
Aging and the Central Nervous System 735
Diagnosis 736
Clinical Localization 736
Computed Tomography 736
Magnetic Resonance Imaging 736
Functional Magnetic Resonance Imaging 736
Positron Emission Tomography 736
Electroencephalography 737
Brainstem Auditory Evoked Potentials 737
Transcranial Doppler Ultrasonography 738
Near-Infrared Spectroscopy 738
Treatment 738
Methods to Control Central Nervous System Damage 738
Treatment of Nonneural Dysfunction 740
Prognosis 740
Physiologic Basis for the Recovery of Function 741
18-1 Special Implications for the PTA 742
Motor Learning Strategies 742
Preferred Practice Patterns 742
References 743
References 743.e1
19 Infectious Disorders of the Central Nervous System 744
Meningitis 744
Definition 744
Incidence 744
Etiologic and Risk Factors 744
Pathogenesis 745
Aseptic (Viral) Meningitis 745
Tuberculous Meningitis 745
Bacterial Meningitis 746
Clinical Manifestations 746
Medical Management 746
Diagnosis. 746
Treatment. 746
Prognosis. 747
Encephalitis 747
Definition 747
Incidence 747
Etiologic and Risk Factors 747
Pathogenesis 748
Clinical Manifestations 749
Medical Management 750
Diagnosis. 750
Treatment. 751
Prognosis. 751
19-1 Special Implications for the PTA 752
Infectious Disorders of the Central Nervous System 752
Preferred Practice Patterns 752
References 752
References 752.e1
20 Degenerative Diseases of the Central Nervous System 753
Amyotrophic Lateral Sclerosis 753
Overview and Definition 753
Incidence 753
Etiologic and Risk Factors 754
Clinical Manifestations 754
Medical Management 755
Diagnosis. 755
Treatment. 757
Prognosis. 758
20-1 Special Implications for Thepta 758
Amyotrophic Lateral Sclerosis 758
Preferred Practice Pattern 758
Alzheimer’s Disease, Alzheimer’s Dementia, and Variants 761
Overview and Definition 761
Pick’s Disease 761
Lewy Body Dementia 761
Frontotemporal Dementia 761
Incidence and Etiologic and Risk Factors 761
Pathogenesis 762
Clinical Manifestations 762
Medical Management 762
Diagnosis. 762
Treatment. 764
Prognosis. 765
20-2 Special Implications for the PTA 765
Alzheimer’s Disease 765
Preferred Practice Pattern 765
Dystonia 766
Definition and Overview 766
Incidence 766
Etiologic Factors 766
Clinical Manifestations 767
Medical Management 767
Diagnosis. 767
Treatment. 767
Prognosis. 768
20-3 Special Implications for the PTA 768
Dystonia 768
Preferred Practice Pattern 768
Huntington’s Disease 769
Overview and Definition 769
Incidence and Etiologic and Risk Factors 769
Pathogenesis 769
Clinical Manifestations 769
Movement Disorders 769
Neuropsychologic and Psychiatric Disorders. 770
Medical Management 770
Diagnosis. 770
Treatment. 771
Prognosis. 771
20-4 Special Implications for the PTA 771
Huntington’s Disease 771
Preferred Practice Pattern 771
Multiple Sclerosis 772
Overview and Definition 772
Incidence 772
Etiologic and Risk Factors 772
Clinical Manifestations 773
Medical Management 775
Diagnosis. 775
Treatment. 779
Prognosis. 780
20-5 Special Implications for the PTA 781
Multiple Sclerosis 781
Preferred Practice Pattern 781
Parkinsonism and Parkinson’s Disease 782
Overview and Definition 782
Incidence 782
Etiologic and Risk Factors 782
Clinical Manifestations 783
Medical Management 785
Diagnosis. 785
Treatment. 786
Prognosis. 788
20-6 Special Implications for the PTA 788
Parkinson’s Disease 788
Preferred Practice Pattern 788
Secondary Parkinson’s Syndrome 789
Disorders with Parkinsonian Characteristics 790
Benign Essential Tremor 790
Progressive Supranuclear Palsy 790
Multiple System Atrophy 790
Olivopontocerebellar Atrophy 790
Wilson’s Disease 790
Restless Leg Syndrome 790
References 790
References 790.e1
21 Stroke 791
Stroke 791
Overview and Definition 791
Incidence 791
Risk Factors 791
Clinical Manifestations 794
Prognosis 794
Ischemic Stroke 794
Pathogenesis 794
Occlusion of Major Arteries. 794
Secondary Vascular Responses. 795
Secondary Neuronal Damage. 795
Clinical Manifestations 796
Syndromes. 796
Middle Cerebral Artery Syndrome. 796
Anterior Cerebral Artery Syndrome. 796
Internal Carotid Artery Syndrome. 796
Posterior Cerebral Artery Syndrome. 796
Vertebral and Posterior Inferior Cerebellar Artery Syndrome. 797
Basilar Artery Syndrome. 798
Superior Cerebellar Artery Syndrome. 798
Anterior Inferior Cerebellar Artery Syndrome. 799
Lacunar Syndrome. 799
Medical Management 799
Diagnosis. 799
Treatment. 800
Prophylaxis 801
Anticoagulation. 801
Lipid-Lowering Agents. 801
Neuroprotection. 801
Nerve Growth. 802
Surgical Intervention. 802
Control of Symptoms. 802
Prognosis. 803
Intracerebral Hemorrhage 803
Overview and Definition 803
Incidence 803
Etiologic and Risk Factors 803
Pathogenesis 804
Clinical Manifestations 804
Syndromes. 804
Putamen. 804
Thalamus. 805
Cerebellum. 805
Pons. 805
Caudate. 805
Internal Capsule. 805
Lobar. 805
Medical Management 805
Diagnosis. 805
Treatment. 806
Prognosis. 806
Subarachnoid Hemorrhage 806
Overview and Definition 806
Etiologic and Risk Factors 806
Clinical Manifestations 807
Medical Management 807
Diagnosis. 807
Treatment. 807
Prognosis. 807
Types of Subarachnoid Hemorrhage 807
Treatment. 808
Subdural Hemorrhage 808
Epidural Hematoma 808
21-1 Special Implications for the PTA 808
Stroke Rehabilitation 808
Preferred Practice Patterns 808
Assessment 810
Intervention 813
References 813
References 813.e1
22 Traumatic Brain Injury 814
Traumatic Brain Injury 814
Overview and Definition 814
Incidence and Risk Factors 814
Etiologic Factors 815
Pathogenesis 815
Vascular Changes 815
Parenchymal Changes 817
Compressive Damage 817
Hypoxia. 818
Hypertension. 818
Cerebral perfusion pressure. 818
Clinical Manifestations 818
Signs and Symptoms 818
Concussion. 818
Levels of Consciousness. 819
Respiratory Impairments. 820
Cognitive and Behavioral Impairments. 820
Pain. 821
Cranial Nerve Damage 821
Motor Deficits 823
Heterotopic Ossification 823
Medical Complications 824
Medical Management 824
Diagnosis. 824
Treatment 825
Acute. 825
Subacute. 827
Rehabilitation. 827
Community Reentry. 827
Prognosis. 827
Traumatic Brain Injury in Children 829
22-1 Special Implications for the PTA 829
Traumatic Brain Injury 829
Acute Management 830
Long-Term Management 830
References 830
References 830.e1
23 Traumatic Spinal Cord Injury 831
Spinal Cord Injury 831
Incidence and Risk Factors 831
Definition and Etiologic Factors 831
Pathogenesis 833
Blood Flow Changes 833
Edema 834
Demyelination 834
Grey Matter 834
Dural Scarring 834
Neural Function 834
Syringomyelia 834
Clinical Manifestations 836
Level of Injury 836
Spinal Cord Injury Syndromes 836
Changes in Muscle Tone 838
Autonomic Nervous System Changes 838
Skeletal Changes 839
Pain 839
Fatigue 839
Respiratory Complications 839
Cardiovascular Conditions 840
Metabolic Conditions 840
Pressure Ulcers 840
Bowel and Bladder Control 840
Sexuality 840
Sleep Disorders 841
Medical Management 841
Diagnosis. 841
Treatment. 842
Emergent Care. 842
Management of Complications. 844
Pain Management. 844
Strategies for Spinal Cord Repair. 845
Stem Cell Transplantation. 846
Prognosis. 846
23-1 Special Implications for the PTA 847
Traumatic Spinal Cord Injury 847
Preferred Practice Patterns 847
References 850
References 850.e1
24 Cerebral Palsy 851
Cerebral Palsy 851
Overview 851
Classification 851
Incidence and Etiologic and Risk Factors 851
Pathogenesis 854
Clinical Manifestations 854
Medical Management 857
Diagnosis. 857
Treatment. 857
Prognosis. 857
24-1 Special Implications for the PTA 858
Cerebral Palsy 858
Preferred Practice Patterns 858
Family-Centered Care 858
Early Intervention (IDEA Part C) 859
Postoperative Concerns 859
Assistive Technology 859
Manual Passive Range-of-Motion Exercise 861
Orthoses 862
Adolescents with Cerebral Palsy 863
Adults with Cerebral Palsy 863
References 864
References 864.e1
25 The Peripheral Nervous System 865
Structure 865
Peripheral Nervous System Changes with Aging 865
Response to Injury 867
Classification of Nerve Injury 867
Classification of Neuropathy 869
Signs and Symptoms of Peripheral Dysfunction 869
Pathogenesis and Diagnosis of Peripheral Dysfunction 871
Hereditary Neuropathies 871
Charcot-Marie-Tooth Disease 872
Incidence 872
Etiology 872
Pathology 872
Clinical Manifestations 872
Medical Management 873
Diagnosis. 873
Treatment. 873
Prognosis. 874
25-1 Special Implications for the PTA 874
Charcot-Marie-Tooth Disease 874
Preferred Practice Patterns 874
Mechanical Injuries: Compression and Entrapment Syndromes 874
Carpal Tunnel Syndrome 874
Incidence 874
Etiology 874
Risk Factors 874
Pathogenesis 875
Clinical Manifestations 875
Medical Management 875
Diagnosis. 875
Treatment. 876
Prognosis. 877
25-2 Special Implications for the PTA 877
Carpal Tunnel Syndrome 877
Preferred Practice Patterns 877
Sciatica 877
Incidence and Etiology 877
Pathogenesis 878
Clinical Manifestations 878
Medical Management 878
Diagnosis. 878
Treatment. 878
Prognosis. 878
25-3 Special Implications for the PTA 879
Sciatica 879
Preferred Practice Patterns 879
Idiopathic Facial Paralysis/Bell’s Palsy 879
Incidence 879
Etiology and Pathogenesis 879
Risk Factors 879
Clinical Manifestations 879
Medical Management 879
Diagnosis. 879
Treatment. 880
Prognosis. 880
25-4 Special Implications for the PTA 880
Bell’s Palsy 880
Preferred Practice Patterns 880
Tardy Ulnar Palsy/Retroepicondylar Palsy 880
Anatomy 880
Etiology 880
Risk Factors 880
Pathogenesis 880
Clinical Manifestations 881
Medical Management 881
Diagnosis. 881
Treatment. 881
Prognosis. 881
Thoracic Outlet Syndrome 882
Definition 882
Etiology 882
Risk Factors 882
Pathogenesis 882
Clinical Manifestations 882
Medical Management 882
Diagnosis. 882
Radiographic Tests. 883
Electrophysiologic Studies. 883
Differential Diagnosis. 884
Treatment. 884
Evolve Chapters e1
E1 Behavioral, Social, and Environmental Factors Contributing to Disease and Dysfunction e1
Overview e1
Behavioral, Social, and Environmental Factors e1
Clinical Models of Health e2
Biomedical Model e2
Biopsychosocial Model e2
Social-Ecologic Model e2
Variations in Client Populations e2
Sociodemographics e2
Health Status e3
Chronic Diseases e3
Americans with Disabilities e3
Geographic Variations e3
Race and Ethnicity e4
Health Disparities e4
Disparities in Rehabilitative Services e5
Factors Contributing to Health Disparities e5
Strategies to Eliminate Disparities e5
Beyond Cultural Competence: Transnational Competence e6
Age and Aging e6
Theories of Aging e6
Life Expectancy e6
Centenarians e6
Children and Adolescents e7
Gender e7
Gender-Based Biology e7
Gender Bias and Gender Equity e7
Gender-Based Patterns of Disease e7
Gender Roles in Health e8
Gender and Exercise e8
Lifestyle Factors That Influence Health e8
Overview e8
Cultural Influences e8
Demographics by Generation e9
Socioeconomic Status e9
Adverse Childhood Experiences e9
E1-1 Special Implications for the PTA e9
Variations in Lifestyle: Adapting Treatment Interventions to the Individual e9
Cultural Awareness e9
Disabilities e10
Homelessness e10
Physical Activity e10
Effects of Physical Activity on Morbidity and Mortality e10
Morbidity. e10
Mortality. e11
Occupational versus Leisure Time Physical Activity e12
Aerobic Capacity versus Musculoskeletal Fitness e12
Prevalence of Physical Activity Behaviors e12
Interventions for Increasing Physical Activity e12
E1-2 Special Implications for the PTA e13
Physical Activity e13
Preferred Practice Patterns e13
Promoting Physical Activity e13
Physical Activity Recommendations42 e13
How Can PTAs Estimate Energy Expenditure? e13
Nutrition e13
Obesity e13
Definition e13
Incidence and Prevalence e14
Etiologic and Risk Factors e14
Pathogenesis e15
Clinical Manifestations e15
Medical Management e16
Prevention. e16
Diagnosis. e16
Treatment. e16
Prognosis. e17
E1-3 Special Implications for the PTA e17
Obesity e17
Preferred Practice Patterns e17
Obesity and Back Pain e18
Obesity and Joint Pain e18
Obesity and Physical Activity e18
Obesity and Operative Complications e18
Prevention e18
Exercise e18
Smoking and Tobacco Use e19
Alcohol and Other Drugs e19
Domestic Violence e19
Child Abuse e20
Intimate Partner Violence e21
Elder Abuse e22
E1-4 Special Implications for the PTA e22
Domestic Violence e22
Child Abuse e23
Intimate Partner Violence e23
Elder Abuse e23
Behavioral Influences on Health e23
Stress, Coping, and Self-Efficacy e24
Stress e24
Definition and Overview. e24
Risk Factors. e24
Pathogenesis. e26
Clinical Manifestations. e26
Coping and Self-Efficacy e27
Measuring Coping. e27
Changing Health Behaviors. e27
Models of Health Behavior Change. e27
E1-5 Special Implications for the PTA e28
Stress, Coping, and Self-Efficacy e28
Preferred Practice Patterns e28
Health Behavior Change e28
Stress e28
Social Support, Networks, and Roles That Influence the Effects of Illness e29
E1-6 Special Implications for the PTA e29
Social Support e29
Environmental Barriers to Health Care e29
References e30
E2 The Psychosocial-Spiritual Impact on Health Care e35
Psychologic Considerations in Health Care e35
Incidence of Underlying Psychosocial-Emotional Trauma e35
Torture e36
Combat e36
Perceptions of Pain e36
E2-1 Special Implications for the PTA e37
Psychologic Considerations in Health Care e37
Effects of Trauma on Brain Development e38
A-Type and B-Type Trauma e38
Stress Reactions e38
Signs of Unresolved Trauma e38
Spiritual Development in the Health Care Profession e39
E2-2 Special Implications for the PTA e40
Spiritual Development e40
Spirituality and Stress e40
Special Role of the PTA e40
Specific Psychologic Conditions e40
Substance Abuse e41
Addiction e42
Incidence e42
Tobacco e43
Effects of Tobacco. e43
Aging and Substance Abuse e43
Pathogenesis e44
Clinical Manifestations and Health Impact e45
Medical Management e47
E2-3 Special Implications for the PTA e47
Substance Abuse e47
Preferred Practice Patterns e47
Interaction of Alcohol with Prescription and Over-the-Counter Drugs e48
Tobacco e48
Smoking Cessation e48
Depressants e49
Stimulants e49
Injection Drug Use e50
Cannabis e51
Eating Disorders e51
Risk Factors e51
Medical Management e51
Prevention. e51
Diagnosis. e52
Treatment. e52
Anorexia Nervosa e52
Overview. e52
Etiology and Risk Factors. e52
Clinical Manifestations. e53
Medical Management e53
Diagnosis. e53
Treatment. e53
APPENDIX A Summary of Standard Precautions APPA1
Historical Perspective APPA1
Universal Precautions APPA1
APPENDIX B Guidelines for Activity and Exercise APPB1
Medications and Exercise APPB1
Guidelines for Monitoring Vital Signs APPB1
Temperature APPB2
Heart Rate (Pulse Rate) APPB3
Abnormal Heart Rate Response APPB4
Heart Rhythm APPB5
Respiratory Rate APPB5
Abnormal Respiratory Rate Response APPB5
Pulse Oximetry APPB5
Supplemental Oxygen APPB6
Blood Pressure APPB6
Pediatrics APPB7
Abnormal Blood Pressure Response APPB7
Guidelines for Aquatic Physical Therapy APPB8
References APPB11
Index 907
A 907
B 910
C 912
D 917
E 918
F 920
G 921
H 922
I 925
J 927
K 928
L 928
M 929
N 932
O 933
P 935
Q 938
R 938
S 940
T 943
U 944
V 945
W 946
X 946
Y 946
Z 946