BOOK
Hepatobiliary Imaging, An Issue of Magnetic Resonance Imaging Clinics of North America, E-Book
(2014)
Additional Information
Book Details
Abstract
This issue, edited by Drs. Peter Liu and Richard Abramson, will comprehensively review imaging of the hepatobiliary system. Articles will include: Hepatic MRI Techniques, Optimization, and Artifacts, MR Contrast Agents for Liver Imaging, Focal Liver Lesion Characterization in Noncirrhotic Patients: An MR Approach, MRI in Cirrhosis and Hepatocellular Carcinoma, Understanding LI-RADS: A Primer for Practical Use, MRI of the Liver after Locoregional and Systemic Therapy, Diffusion Weighted Imaging of the Liver: Techniques and Applications, Hepatic Iron and Fat Quantification Techniques, Perfusion Imaging in Liver MRI, MR Elastography, Treatment Planning Before Hepatobiliary Surgery: Clinical and Imaging Considerations, MRI/MRCP of Benign and Malignant Biliary Conditions, and more!
Table of Contents
Section Title | Page | Action | Price |
---|---|---|---|
Front Cover | Cover | ||
Hepatobiliary Imaging | i | ||
Copyright\r | ii | ||
Contributors | iii | ||
Contents | vii | ||
Magnetic Resonance Imaging Clinics of North America \r | x | ||
Foreword Hepatobiliary Imaging\r | xiii | ||
Preface Hepatobiliary Imaging\r | xv | ||
Hepatic MR Imaging Techniques, Optimization, and Artifacts | 263 | ||
Key points | 263 | ||
Introduction | 263 | ||
The basic hepatic MR imaging examination | 264 | ||
Individual pulse sequences | 264 | ||
Localizer Images | 264 | ||
Magnetic Resonance Contrast Agents for Liver Imaging | 283 | ||
Key points | 283 | ||
Introduction | 283 | ||
Contrast agent properties | 283 | ||
Relaxivity | 284 | ||
Biodistribution | 285 | ||
Extracellular contrast agents | 285 | ||
Hepatobiliary agents | 285 | ||
Blood pool agents | 286 | ||
Adverse events and toxicity | 287 | ||
Gadolinium-based Agents | 288 | ||
Iron-based Agents | 289 | ||
Injection protocol and arterial phase acquisition | 289 | ||
Summary | 290 | ||
References | 290 | ||
Appendix 1 | 292 | ||
Pregnancy | 293 | ||
Breast-feeding Mothers | 293 | ||
MR Characterization of Focal Liver Lesions | 295 | ||
Key points | 295 | ||
Pearl 1: the T1 pearl: a focal lesion that is isointense to hyperintense to liver on T1-weighted images is hepatocellular i ... | 295 | ||
FNH | 296 | ||
IHCA | 298 | ||
The exceptions | 299 | ||
Nonhepatocellular Focal Liver Lesions in a Liver Containing Background Moderate or Marked Steatosis | 299 | ||
Hemorrhagic Metastases to the Liver | 299 | ||
Hemorrhagic Cysts of the Liver | 300 | ||
Pearl 2: the chemical shift pearl: focal liver lesions that lose signal intensity on opposed-phase imaging contain lipid an ... | 300 | ||
RN and HCC | 301 | ||
HNF-1α Hepatic Adenoma | 302 | ||
Nodular Steatosis | 302 | ||
The exceptions | 303 | ||
Clear Cell Renal Cell Carcinoma | 303 | ||
Liposarcoma and Germ Cell Neoplasms | 303 | ||
Ethiodized Oil | 304 | ||
Hepatic Angiomyolipoma | 305 | ||
Pearl 3 (in 3 parts): the iron pearls | 305 | ||
Pearl 4 (in 3 parts): the T2 pearls | 307 | ||
The exceptions | 309 | ||
Hepatic Adenomas and FNH Can Have Components That Are Isointense to Spleen | 309 | ||
Mucinous Adenocarcinoma Metastases Can Be Hyperintense to Spleen on Heavily T2-Weighted Images and Can Mimic Nonsolid Benig ... | 309 | ||
Summary | 309 | ||
References | 310 | ||
MR Imaging in Cirrhosis and Hepatocellular Carcinoma | 315 | ||
Key points | 315 | ||
Introduction | 315 | ||
Surveillance | 316 | ||
Technique | 316 | ||
Cirrhosis | 316 | ||
Findings of Cirrhosis | 316 | ||
RNs | 318 | ||
Dysplastic Nodules | 319 | ||
Hepatocellular carcinoma | 320 | ||
Key imaging features of HCC | 320 | ||
Arterial Phase Hyperenhancement | 320 | ||
Washout | 321 | ||
Capsular Enhancement | 321 | ||
Other findings of HCC | 322 | ||
T1W Signal | 322 | ||
Fatty Metamorphosis | 322 | ||
T2W Signal | 322 | ||
DWI | 322 | ||
Hepatocyte-specific Contrast Agents | 323 | ||
Mosaic Pattern | 325 | ||
Nodule Within a Nodule Appearance | 325 | ||
Vascular Invasion | 326 | ||
HCC subtypes | 327 | ||
Diffuse HCC | 327 | ||
Scirrhous HCC | 327 | ||
Combined Hepatocellular Cholangiocarcinomas | 328 | ||
HCC mimics and other masses in cirrhotic livers | 328 | ||
Intrahepatic Mass-forming Cholangiocarcinoma | 328 | ||
Metastases | 328 | ||
Large RNs in Budd-Chiari Syndrome | 329 | ||
Confluent Hepatic Fibrosis | 329 | ||
Nodules less than 20 mm with atypical enhancement patterns | 329 | ||
Small (<20 mm) Arterially Hyperenhancing Nodules | 329 | ||
Small (<20 mm) Hypovascular Nodules | 330 | ||
Summary | 330 | ||
References | 330 | ||
Understanding LI-RADS | 337 | ||
Key points | 337 | ||
Introduction | 337 | ||
Observations | 338 | ||
Categories | 338 | ||
Algorithm | 339 | ||
Major features | 341 | ||
LI-RADS table | 346 | ||
Ancillary features | 348 | ||
Tie-breaking rules | 349 | ||
Other features of LI-RADS | 349 | ||
Future directions | 351 | ||
Summary | 351 | ||
References | 351 | ||
Magnetic Resonance Imaging of the Liver After Loco-Regional and Systemic Therapy | 353 | ||
Key points | 353 | ||
Introduction | 353 | ||
Loco-regional and systemic therapy | 354 | ||
Transarterial Embolization | 354 | ||
Transarterial Chemotherapy with and Without Embolization | 355 | ||
TACE with Drug-Eluting Beads | 355 | ||
Transarterial Radioembolization | 355 | ||
Tissue Ablation | 356 | ||
Systemic Therapy | 357 | ||
Role of MR imaging in the assessment of treatment response | 357 | ||
Anatomic MR Imaging Metrics | 357 | ||
Functional Volumetric MR Imaging Metrics | 358 | ||
DWI | 358 | ||
Quantitative Contrast-Enhanced MR Imaging | 358 | ||
Perfusion Fraction MR Imaging | 361 | ||
Multiparametric Volumetric Functional MR Imaging | 362 | ||
Imaging of hepatic tumors after LRT and systemic therapy | 362 | ||
HCC | 362 | ||
Cholangiocarcinoma | 364 | ||
Colorectal Liver Metastases | 366 | ||
Neuroendocrine Liver Metastases | 366 | ||
Islet Cell Tumor Metastases | 367 | ||
Summary | 368 | ||
References | 368 | ||
Diffusion-Weighted Imaging of the Liver | 373 | ||
Key points | 373 | ||
Introduction | 373 | ||
DWI technique | 374 | ||
Concepts | 374 | ||
Principles of molecular diffusion | 374 | ||
DWI physics | 374 | ||
Quantification of diffusion properties in tissues | 374 | ||
Quality control | 375 | ||
Reproducibility and repeatability | 375 | ||
Diffusion Acquisition | 375 | ||
Imaging strategy | 375 | ||
Control of physiologic motion | 375 | ||
Parallel imaging | 376 | ||
Effect of magnetic field strength: 1.5 T versus 3.0 T | 376 | ||
Liver applications | 376 | ||
Lesion Detection | 376 | ||
Liver metastases | 376 | ||
HCC | 378 | ||
Cholangiocarcinoma | 380 | ||
Lesion Characterization | 381 | ||
Qualitative assessment | 381 | ||
Quantitative assessment | 382 | ||
Common pitfalls in using DWI for lesion characterization | 382 | ||
Tumor Treatment Response | 383 | ||
Liver Fibrosis and Cirrhosis | 385 | ||
Limitations | 385 | ||
Future directions | 387 | ||
IVIM in the Clinic | 387 | ||
Noninvasive detection of liver fibrosis | 387 | ||
Liver lesion characterization | 388 | ||
Combination and Comparison with Positron Emission Tomography/MR Imaging | 388 | ||
New DWI Sequences | 388 | ||
Summary | 389 | ||
References | 389 | ||
Quantification of Hepatic Fat and Iron with Magnetic Resonance Imaging | 397 | ||
Key points | 397 | ||
Introduction | 397 | ||
NAFLD | 398 | ||
NASH and cryptogenic cirrhosis | 399 | ||
HCC | 399 | ||
Hepatic iron overload | 400 | ||
Treatment of fatty liver disease and iron overload | 401 | ||
Methods of assessing of hepatic fat and iron | 402 | ||
Ultrasound | 402 | ||
Computed Tomography | 403 | ||
Nontargeted Liver Biopsy | 403 | ||
Phlebotomy | 403 | ||
Qualitative MR Imaging Techniques | 404 | ||
MR imaging as a quantitative biomarker | 406 | ||
Hepatic Fat | 406 | ||
Hepatic Iron | 409 | ||
Summary | 412 | ||
References | 412 | ||
Perfusion Imaging in Liver MRI | 417 | ||
Key points | 417 | ||
Introduction | 417 | ||
Qualitative explanation of dynamic clinical MR imaging | 418 | ||
Qualitative explanation of DCE-MRI tracer kinetic modeling | 418 | ||
Single-compartment versus dual-compartment | 421 | ||
Single versus dual input | 422 | ||
Conventional compartment model versus distributed parameter model | 422 | ||
Model-free approaches | 423 | ||
Initial Area Under the Curve | 423 | ||
Hepatic Perfusion Index | 423 | ||
Choice of method | 423 | ||
DCE-MRI technique | 425 | ||
Clinical applications | 426 | ||
Predicting Liver Micrometastases | 426 | ||
Predicting Response to Therapy | 426 | ||
Assessing Liver Fibrosis and Cirrhosis | 427 | ||
Summary | 430 | ||
References | 430 | ||
Magnetic Resonance Elastography of Liver | 433 | ||
Key points | 433 | ||
Introduction | 433 | ||
Elastography | 434 | ||
Magnetic resonance elastography | 434 | ||
Principle of MRE | 434 | ||
Technique of Liver MRE | 434 | ||
Generating mechanical shear waves in liver | 435 | ||
Imaging the propagating shear waves (MRE sequence) | 435 | ||
Generation of stiffness map (elastogram) | 436 | ||
Calculating Liver Stiffness | 436 | ||
Clinical applications of liver MRE | 437 | ||
Detection and Staging of Liver Fibrosis | 439 | ||
Differentiation of Simple Steatosis from Nonalcoholic Steatohepatitis | 439 | ||
Other Applications | 440 | ||
Evaluation of focal lesions | 440 | ||
Clinical follow-up and treatment response assessment | 440 | ||
Emerging applications | 440 | ||
Limitations of MRE | 440 | ||
Future directions | 443 | ||
Summary | 443 | ||
References | 443 | ||
Presurgical Planning for Hepatobiliary Malignancies | 447 | ||
Key points | 447 | ||
Introduction | 447 | ||
MR imaging protocols | 448 | ||
Hepatic parenchymal, vascular, and biliary anatomy | 448 | ||
Functional considerations | 450 | ||
HCC | 453 | ||
Colorectal metastases | 456 | ||
Cholangiocarcinoma | 458 | ||
Summary | 463 | ||
References | 463 | ||
MR Imaging of Benign and Malignant Biliary Conditions | 467 | ||
Key points | 467 | ||
Introduction | 467 | ||
MR imaging methodology | 468 | ||
MR Cholangiopancreatography | 468 | ||
Soft Tissue Imaging | 469 | ||
T2W and steady-state free precession imaging | 469 | ||
T1W imaging | 469 | ||
Hepatobiliary-Specific Contrast Agents | 470 | ||
The evolving role of MR imaging and endoscopic retrograde cholangiopancreatography | 471 | ||
Benign hepatobiliary pathology | 471 | ||
Biliary Obstruction | 471 | ||
Choledocholithiasis | 471 | ||
Portal biliopathy | 471 | ||
Cystic Disease of the Bile Ducts | 472 | ||
Inflammatory Diseases of the Bile Ducts | 474 | ||
Bile stasis | 474 | ||
Infectious cholangitis | 474 | ||
Primary sclerosing cholangitis | 475 | ||
IgG4-related sclerosing cholangitis | 476 | ||
Acquired immunodeficiency cholangiopathy | 476 | ||
Primary biliary cirrhosis | 480 | ||
Surgical Complications | 480 | ||
Bile duct injury | 480 | ||
Post liver transplant biliary complications | 480 | ||
Malignant hepatobiliary pathology | 480 | ||
Cholangiocarcinoma | 480 | ||
Lymphoma | 483 | ||
Metastatic Disease | 484 | ||
Intraductal Papillary Neoplasms of the Bile Duct | 484 | ||
Summary | 486 | ||
References | 486 | ||
Index | 489 |