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Emergency and Critical Care, An Issue of Veterinary Clinics of North America: Equine Practice, E-Book

Emergency and Critical Care, An Issue of Veterinary Clinics of North America: Equine Practice, E-Book

Diana M. Hassel

(2014)

Additional Information

Abstract

Drs. Diana Hassel and Vanessa Cook have put together an expert team of authors focused on emergency and critical care topics. Articles include: Field Triage of the Neonatal Foal, CPR in the neonatal foal: has RECOVER changed our approach?, Update on the management of neonatal sepsis, SIRS or endotoxemia?, Ultrasound of the equine acute abdomen, Evaluation of the colic: Decision for referral, The utility of lactate in critically ill adults and neonates, Crystalloid and colloid therapy, Acute hemorrhage and blood transfusions, Coagulopathies, and more!

Table of Contents

Section Title Page Action Price
Front Cover Cover
Emergency andCritical Care i
Copyright ii
Contributors iii
Contents vii
Veterinary Clinics Of North America: Equine Practice xi
Preface xiii
Field Triage of the Neonatal Foal 283
Key points 283
Introduction 283
Physical examination of the newborn foal 283
Dysphagia/Loss of Suckle/Milk Regurgitation 285
Triage of the weak neonatal foal 286
Sepsis 286
PAS 286
Prematurity/Dysmaturity 287
Specific Treatment of Sepsis 287
Specific Treatment of PAS 287
Specific Treatment of Prematurity 288
General therapy for the weak recumbent foal 288
Nutrition Support 288
Partial parenteral nutrition 289
Enteral feeds 289
FPT 290
IV Fluid Support of the Foal 290
Maintenance fluid therapy 290
Supportive Care 291
Respiratory Support 291
Other common disorders of the neonate 292
Neonatal Isoerythrolysis 292
Disorders of the Lungs 292
Pneumonia 292
Treatment 292
Apneustic breathing 293
CPR in the Neonatal Foal 301
Key points 301
What is RECOVER? 301
Causes for CPA in equine neonates 302
CPR training and team dynamics 302
Preparation 303
CPR—basic and advanced life support 303
Basic life support 303
What to Do 304
Patient Positioning 304
Ventilation 304
RECOVER Recommendations for Ventilation 305
Thoracic Compressions 305
RECOVER Recommendations 305
Recommendation 306
Advanced life support 306
Vasopressor and Vagolytic Therapy 306
Epinephrine dose 306
Vasopressin Versus Epinephrine 307
Atropine 307
Defibrillation 307
Defibrillation Technique 307
Antiarrhythmic Drug Therapy 307
Electrolyte Therapy 308
Other Therapies 308
Intratracheal Drug Administration 308
Open Chest CPR 308
Monitoring 309
Monitoring Patients During CPA 309
When to Stop 310
Post–cardiac arrest care 310
Resuscitation at the time of foaling 311
Summary 311
References 312
Update on the Management of Neonatal Sepsis in Horses 317
Key points 317
Introduction 317
The septic neonatal foal 318
Management strategies in neonatal sepsis 321
Infection Control 322
Antimicrobials 322
Plasma therapy 322
Hemodynamic Support 324
Fluid therapy 324
Vasoactive agents 325
Respiratory support 326
Antimediator Therapy 327
Supportive therapy 329
Tight Glucose Control 330
Corticosteroid Replacement Therapy 330
Summary 332
References 333
Is it the Systemic Inflammatory Response Syndrome or Endotoxemia in Horses with Colic? 337
Key points 337
Introduction 337
SIRS 338
The innate immune system 339
Pattern-recognition receptors and their role in equine SIRS 339
TLR4 and its interactions with LPS 340
Signaling pathways initiated by TLR4 activation 340
Other equine TLRs and their PAMPs 341
Mediators released via TLR activation and their physiologic effects 343
Differences in responses of equine cells to TLR activation 344
Responses of Equine TLR4 to LPS 344
Agonist/Antagonist LPS Responses 344
Equine-Specific Cellular Responses to Flagellin 345
The focus on endotoxemia 345
Detection of LPS 347
SIRS or endotoxemia? 347
Treatment 347
Current Treatment Approach 347
Caution Regarding Extrapolating Future Treatments to Horses 348
References 348
Ultrasound of the Equine Acute Abdomen 353
Key points 353
Introduction and clinical indications 353
Technique and Equipment 354
Patient preparation 355
Transducers and ultrasound machines 355
Scanning technique 355
Limited examination 355
FLASH technique 355
Full examination 356
Machine settings 356
Examiner experience and diagnostic complexity 356
Normal Ultrasonographic Anatomy of the Equine Abdomen 356
Left abdomen 357
Right abdomen 357
Ventrum 358
Gastric Abnormalities 359
Small Intestinal Abnormalities 360
Small intestinal strangulating obstructions 360
Intussusception 360
Proximal enteritis 361
Other small intestinal lesions 362
Duodenal abnormalities 362
Large Intestinal Abnormalities 363
Left dorsal displacement 363
Right dorsal displacement 364
Colon torsion 365
Colitis 366
Intussusception 366
Sand/Enteroliths 367
Peritoneal Fluid 367
Masses, Neoplasia, and Abscessation 370
Abdominal neoplasia 370
Abdominal abscessation 371
Other 373
Urolithiasis 373
Cholelithiasis 374
Thoracic and cardiac causes of colic 376
Pleuritis 376
Pericarditis 376
Aortic root disease 376
Diaphragmatic hernia 377
References 378
Evaluation of the Colic in Horses 383
Key points 383
Introduction: nature of the problem 383
Patient history and signalment 384
Physical examination 385
Pain Assessment and General Appearance 387
Heart Rate 387
Temperature 388
Gastrointestinal Motility 388
Rectal Palpation 388
Presence of Gastric Reflux 389
Imaging and additional testing 390
Transabdominal Ultrasound 390
Abdominocentesis 391
Lactate 393
Glucose 394
Summary 395
References 395
Blood Lactate Measurement and Interpretation in Critically Ill Equine Adults and Neonates 399
Key points 399
Introduction 399
Measuring lactate concentrations 400
Lactate metabolism in the healthy animal 401
Lactate metabolism in disease 402
Increased Na+/K+–Adenosine Triphosphatase Activity in Response to Inflammatory Mediators 402
Inhibition of PDH 403
Lactate Production by Leukocytes 403
Decreased Hepatic Clearance 403
Other Potential Causes of Hyperlactatemia 404
Source of Lactate During Disease 404
Interpretation of blood lactate concentrations in critically ill horses 404
Lactate Measurement and Interpretation in Adult Horses 405
Lactate Measurement and Interpretation in Equine Neonates 406
Limitations in the Clinical Use of Blood Lactate Concentrations 408
Summary 409
References 409
Crystalloid and Colloid Therapy 415
Key points 415
Hyperchloremia 416
Colloid research revisited 417
The No-Absorption Rule 417
Retraction of Studies Supporting Colloid Use 418
Remaining Evidence Addressing Colloid Use 418
Fluid overload 419
Treatment of Fluid Overload 420
The basic components of a fluid therapy plan 421
Are Intravenous Fluids Indicated? 421
Type of Fluid 422
Initial Resuscitation Fluid 422
Rate of Fluid Administration 422
End Points to Fluid Administration 422
References 423
Acute Hemorrhage and Blood Transfusions in Horses 427
Key points 427
Introduction 427
Acute hemorrhage 427
Recognizing Acute Hemorrhage in the Horse 427
Physiologic Hemostasis and Medical Management 428
Surgical and Topical Hemostasis 429
Blood transfusion 430
Criteria for Transfusion 430
Blood Products 430
Blood Donors and Pretransfusion Testing 431
Blood Collection and Storage 431
Transfusion Volume and Technique 433
Adverse Effects 433
Alternative Sources of Blood 434
Summary 434
References 434
Coagulopathies in Horses 437
Key points 437
Introduction 437
Nature of the Problem 437
Definitions 437
Normal hemostasis 437
Coagulopathy 439
Clinical findings 440
Physical Examination 440
Excessive bleeding 440
Excessive thrombosis 440
DIC 440
Underlying Disease 441
Diagnostics 441
Clinical Pathology 441
Other Tests 441
Decision Algorithms 444
Treatment options 445
For Excessive Bleeding 445
For Excessive Thrombosis 445
References 449
Trauma and Wound Management 453
Key points 453
Introduction 453
Classification of wounding potential 454
Impact energy 454
Bullet design 456
Tissues involved 457
Bullet wound classification system 458
Energy 458
Vital structures involved 459
Wound 459
Fractures 459
Contamination 459
Treatment of bullet wounds 460
Head, neck, and spine injuries 461
Thoracic wounds 462
Abdominal wounds 463
Soft tissue injuries and musculoskeletal trauma 463
Legal considerations 464
Acknowledgments 465
References 465
Infection Control in Equine Critical Care Settings 467
Key points 467
Importance of infection control in the critical care setting 467
General infection control concepts 468
Challenges of infection control in the critical care setting 469
Risks Associated with Caretaker-Patient Contacts 469
Risks Associated with Intravenous Catheterization 470
Special Considerations When Managing Critically Ill Foals 470
Risks associated with managing critical care patients 470
What Are the Risks? 470
Specific Agents of Concern 471
Eliminating Environmental Persistence of Potential Pathogens 471
Summary 472
References 472
Index 475