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Practical Obstetrics And Gynaecology Handbook For O&g Clinicians And General Practitioners (2nd Edition)

Practical Obstetrics And Gynaecology Handbook For O&g Clinicians And General Practitioners (2nd Edition)

Tan Thiam Chye | Tan Kim Teng | Tay Eng Hseon

(2014)

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Book Details

Abstract

This handbook provides an evidence-based approach to common obstetrics & gynaecological problems faced by O & G clinicians and general practitioners in their daily practice. It is the only book available with current evidence-based recommendations and protocols in O & G.Compiled by experienced experts, this new edition contains 24 new chapters. The existing chapters have been updated using the latest evidence. The authors have included multiple flow charts and detailed practical approaches to various gynaecology and obstetric issues. The book will be a valuable and quick practical guide to everyone — not only to general practitioners and O & G clinicians, but also to medical students and resident doctors. Topics like “Approach to Ectopic Pregnancy” and “Pelvic Inflammatory Disease” will provide invaluable guidance to even emergency medicine doctors.

Table of Contents

Section Title Page Action Price
CONTENTS xxi
Foreword v
History of KK Women’s and Children’s Hospital vii
Preface xi
About the Authors and Chief Editor xiii
Acknowledgements xvii
PART 1: OBSTETRICS 1
Chapter 1 Pre-Conception Preparation 3
OBJECTIVES: 3
TO IMPROVE PREGNANCY OUTCOME 3
1. Optimising Medical Conditions Prior to Pregnancy — to Improve the Prognosis for both Mother and Baby 3
2. Avoid Teratogenic Drugs 10
3. Screen for Infections and Genetic Blood Disorders — Treat, Immunise and Counsel 10
4. Encourage Appropriate Counselling Sessions 12
Chapter 2 Routine Antenatal Follow-Up 17
OBJECTIVES OF ANTENATAL VISITS 17
Warning Symptoms in Pregnancy 20
Warning signs in pregnancy 21
Chapter 3 Vaccination in Pregnancy 23
GENERAL PRINCIPLES 23
VACCINATIONS CONTRAINDICATED IN PREGNANCY 24
Chapter 4 Approach to Bleeding in Early Pregnancy 29
Causes 29
Management of Early Pregnancy Bleeding 30
Chapter 5 Approach to Spontaneous Miscarriage 35
Aetiologies 35
Spontaneous Miscarriages 37
Chapter 6 Approach to Recurrent Spontaneous Miscarriage (RSM) 41
Common Aetiologies 41
Chapter 7 Approach to Abdominal Pain in Pregnancy 45
Chapter 8 Obstetric & Gynaecological (O&G) Causes of Abdominal Pain in Early Pregnancy 49
Chapter 9 Obstetric & Gynaecological (O&G) Causes of Abdominal Pain in Late Pregnancy 55
Chapter 10 Non Obstetric & Gynaecological (Non O&G) Causes of Abdominal Pain in Pregnancy: Simple Approach by Site of Pain 63
Chapter 11 Non Obstetric & Gynaecological (Non O&G) Causes of Abdominal Pain in Pregnancy 67
Chapter 12 Approach to Ectopic Pregnancy (EP) 83
Ultrasound Features of Normal Early Gestation 88
Ultrasound Features of Tubal Ectopic Gestation 88
1. Medical Management of Ectopic Pregnancy 89
2. Surgical Management of Ectopic Pregnancy 91
3. Expectant Management of Ectopic Pregnancy 93
Other Types of Ectopic Pregnancies (EP) 94
Chapter 13 Approach to Gestational Trophoblastic Disease (GTD) 99
Types of GTD 99
Chapter 14 Termination of Pregnancy (TOP) 103
Management of Asherman Syndrome (Adhesions or Fibrosis within the Uterine Cavity) 108
Chapter 15 Medical Disorders and Potential Risk Factors in Pregnancy 111
Chapter 16 Multiple Pregnancy 147
TWINS 147
Antenatal Care 148
Monochorionic, Monoamniotic Twins 148
Complications of Multiple Pregnancy — Foetal Causes 148
Chapter 17 Infections in Pregnancy 159
Antenatal Screening for Infection 159
Management of Infection in Pregnancy 159
List of Infections in Pregnancy 160
4. Cytomegalovirus (CMV) Infection 162
5. Dengue Infection 164
6. Genital Warts Infection 165
7. Gonorrhoea 166
8. Group B Streptococcus 166
9. Hand-Foot-Mouth Disease (HFMD) Infection 167
10. Hepatitis B Infection 168
11. Hepatitis C Infection 169
12. Hepatitis E Infection 169
13. Herpes Simplex Virus (HSV) Infection 170
14. H1N1 Influenza Infection 171
15. HIV Infection 172
16. Listeriosis Infection 173
17. Malaria Infection 174
18. Parvovirus B19 Infection 176
19. Rubella Infection 178
20. Shingles (Herpes/Varicella-Zoster Virus) Infection 180
21. Syphilis (Treponema pallidum) Infection 180
22. Toxoplasmosis Infection 181
23. Trichromoniasis 182
24. Tuberculosis Infection 183
25. Varicella Zoster (Chickenpox) Infection 184
Chapter 18 Skin Disorders in Pregnancy 187
1. Hormone-related Skin Disorders 187
2. Pre-existing Skin Disorders 187
3. Pregnancy-specific Skin Disorders 187
Chapter 19 Approach to Depression in Pregnancy 195
Antenatal Depression is associated with 195
Postnatal Depression is associated with 195
Recognition of symptoms is important 196
Screening for Depression 197
Treatment 198
Chapter 20 Medications in Pregnancy and Lactation 199
Food Drug Administration (FDA) Classification for Drugs in Pregnancy 200
Teratogenic Mechanisms Associated with Medication Use 201
Drugs to Avoid in Pregnancy 202
Drugs to Avoid in Pregnancy for G6PD Deficient Individuals 205
Commonly Prescribed Medications during Pregnancy 207
Special Conditions in Pregnancy 222
Hyperthyroidism 222
Depression 226
Indications of Anti-D Immunoglobulin Administration in Pregnancy 228
Indications of Aspirin Use in Pregnancy 230
Dosage of Aspirin 231
Mechanism of Action of Aspirin 231
Chapter 21 Approach to Postnatal Problems 233
Bladder Care After Vaginal Delivery 235
Postnatal Problems 236
Risk factors of sepsis 240
Chapter 22 Lactation and Breastfeeding 243
Introduction 243
Benefits of Breastfeeding 243
CONTRAINDICATIONS OF BREASTFEEDING 244
ANTENATAL PREPARATION 244
Management of Breastfeeding Related Problems 245
Treatment of breast engorgement includes 247
Chapter 23 Frequently Asked Questions on Pregnancy 253
1. Air Travel in Pregnancy 253
2. Carrying heavy things in pregnancy 255
3. Clothing in pregnancy 255
4. Dental health concerns in pregnancy 255
5. Does Epidural Cause Backache? 260
6. Exercise in Pregnancy 260
7. Facial Treatments in Pregnancy 260
8. Food, smoking and alcohol in pregnancy 261
9. Hair-Dyeing, Hair Rebonding and Perming in Pregnancy 263
10. House Paint in Pregnancy 263
11. Ideal Weight Gain in Pregnancy 264
12. Insecticides in Pregnancy 264
13. Massage/Aromatherapy in Pregnancy 264
14. Mobile Phones in Pregnancy 265
15. Sauna/Steam in Pregnancy 265
16. Sex in Pregnancy 265
17. Tattoos in Pregnancy 265
18. Use of Mosquito Repellants containing DEET in Pregnancy 266
19. Use of Over the Counter (OTC) Slimming Pillsin Pregnancy 266
20. Working on Computers/ Video Display Terminals/Photocopier/Printerin Pregnancy — Safe? 266
21. X-rays/Radiation Exposure in Pregnancy 266
22. Breastfeeding after Breast Augmentation Surgery 268
PART 2: INVESTIGATIONS IN OBSTETRICS 269
Chapter 24 Routine Antenatal Blood Investigations and Infective Screening 271
Routine Antenatal Blood Investigations 271
Routine Antenatal Infective Screening 273
Chapter 25 Approach to Prenatal Screening for Thalassaemia 279
Alpha-Thalassaemia 280
Beta-thalassaemia 282
HbE Trait 283
Alpha-thalassaemia/Beta-thalassaemia Coinheritance 285
Sickle Cell Disease 286
Chapter 26 Miscellaneous Antenatal Blood Investigations 295
Miscellaneous Antenatal Blood Tests 295
Pre-Eclampsia Blood/Urine Investigations 297
Urine Protein: Creatinine Ratio 298
Chapter 27 Screening for Chromosomal Defects 299
Introduction 299
Various Screening Tests for Down Syndrome 300
First Trimester Screening Available in KK Hospital 303
Nuchal Translucency 305
Noninvasive Prenatal Testing (NIPT) for Foetal Aneuploidy 308
Chapter 28 Prenatal Invasive Diagnostic Tests 311
Additional Information 318
Chapter 29 Ultrasonography and Foetal Doppler in Obstetrics 319
1. Dating Scan 319
2. Screening Scan 319
3. Growth Scan 320
4. Foetal Doppler Studies in Obstetrics 321
Common Indications for Doppler Flow Velocimetry Studies Include 322
Chapter 30 Approach to Screening Scan Foetal Abnormalities 325
1. Head, Neck & Spine Abnormalities 326
2. Abnormalities in the Chest 329
3. Abnormalities in the Abdomen 331
4. Abnormalities in the Pelvis 333
5. Other Ultrasound Scan Abnormalities 334
Chapter 31 Laboratory Values in Normal Pregnancy 337
Endocrine Values 344
Lipids 347
Chapter 32 An Overview of Serum Human Chorionic Gonadotrophin (HCG) 349
Sources 349
hcg Level in Pregnancy 351
hcg Level in Relation to Spontaneous Miscarriage 352
hcg Level in Relation to Gestational Trophoblastic Disease (GTD) 352
hcg Level in Relation to Ectopic Pregancy 353
PART 3: GYNAECOLOGY 357
Chapter 33 Amenorrhoea 359
Primary Amenorrhoea 359
Management of Primary Amenorrhoea 361
Secondary Amenorrhoea 361
Chapter 34 Abnormal Uterine Bleeding (AUB) 365
Definition of AUB 365
Classification of AUB-FIGO 366
Approach to Management of AUB 368
Treatment for AUB 370
Medications Used for AUB 372
Chapter 35 Adolescent Abnormal Uterine Bleeding (AUB) 381
Incidence and Facts 381
Investigations of Adolescent AUB 383
Management of Adolescent AUB 384
Chapter 36 Premenstrual Syndrome (PMS) 385
Definition of Different Types of Premenstrual Syndrome 385
Epidemiology 386
Risk Factors 386
Clinical Features of PMS 386
Diagnosis of PMS 387
Assessment of PMS 387
Treatment of PMS 389
GnRH Analogues 390
Chapter 37 Dysmenorrhoea 391
Causes 391
1. Typical Symptoms of Primary Dysmenorrhoea 392
2. Typical Symptoms of Secondary Dysmenorrhoea 392
3. Findings Suggestive of Pelvic Pathology Consistent with Secondary Dysmenorrhoea include 392
Management of Dysmenorrhoea 393
Chapter 38 Chronic Pelvic Pain (CPP) 395
Investigations for Chronic Pelvic Pain 397
Management of Chronic Pelvic Pain 398
Other Treatments 399
Chapter 39 Polycystic Ovarian Syndrome (PCOS) 401
Epidemiology 402
High Risk Groups 402
Assessment of PCOS 402
Management of PCOS 404
Chapter 40 Approach to Gynaecological Cancers 411
Special Considerations 411
1. Carcinoma of the Cervix 413
2. Carcinoma of the Fallopian Tube 415
3. Carcinoma of the Ovary 417
4. Carcinoma of the Uterus (endometrium) 420
5. Carcinoma of the Vulva/Vagina 422
Chapter 41 Pap Smear Screening and Management of Abnormal Pap Smears 425
Cervical Screening Singapore programme 428
Bethesda 2001 Cervical Cytology Classification — Negative for Squamous Intraepithelial Lesion or Malignancy 429
Sampling Devices for Pap Smear 431
How to Obtain Samples 433
Follow Up Management of Pap Smears 436
Referral Criteria for Colposcopy 440
What is Colposcopy? How to explain to our patients? 441
Summary of Treatment for Pre-Invasive Cervical Lesions 444
Cone Biopsy 445
Atypical Glandular Cells 447
Adenocarcinoma in situ (AIS) 448
Chapter 42 Postcoital Bleeding (PCB) 449
Causes of PCB 449
Chapter 43 Human Papilloma (HPV) Vaccines and HPV Testing — Salient Facts for Clinical Practice 453
Facts about Cervical Cancer 453
Human Papilloma Virus and Cervical Cancers and Other Cancers 453
Human Papilloma Virus and Genital Warts 454
Clinical Manifestations 454
Natural History of hr-HPV Infection and pathogenesis of Cervical Cancer 454
The Cervical Epithelium and Cervical Cancers 455
Cervical Intraepithelial Neoplasia (CIN) and Squamous Cell Carcinoma (SCC) 455
Adenocarcinoma In situ (AIS) and Adenocarcinoma — Why does it Need Special Attention? 456
Overview of Treatment for Cervical Pre-Cancers 456
Pap Smear Screening 457
High-Risk(hr-) HPV Testing 457
Self-Sampling for Cervical Screening 458
HPV Vaccination 459
Chapter 44 Vulvar and Vaginal Lesions 463
Vulvar Disorders 463
1. Normal anatomical variants. No treatment required 471
2. Vulvar Pigmented Lesions 472
3. Vulvar Ulcers 474
4. Vulvar Nodules, Cysts or Tumours 479
5. Vulvar Dermatoses 481
Chapter 45 Postmenopausal Bleeding (PMB) 497
Causes of PMB 497
Management of Postmenopausal Bleeding (PMB) 498
Chapter 46 Thickened Endometrium 501
Chapter 47 Polyps (Cervical/Endometrial) 511
Cervical Polyps 511
Endometrial Polyps 513
Chapter 48 Fibroids 517
Exact Aetiology 517
Location of Fibroids 517
Risk Factors 518
Physical Examination 520
Investigations 521
Management of fibroids 522
Fertility and Fibroids 527
Pregnancy and Fibroids 527
Chapter 49 Endometriosis and Adenomyosis 531
Investigations for Endometriosis 533
Differential diagnosis of endometriosis 534
1. Endometriosis Associated Pain 535
2. Endometriosis Associated Subfertility 536
Definition of Adenomyosis 538
Differential Diagnosis of Adenomyosis 538
Investigations of Adenomyosis 539
Chapter 50 Ovarian Cyst 541
Types of Adnexal Masses and Management of Ovarian Cysts in Women 541
Pregnancy with Adnexal Mass 545
Chapter 51 Pelvic Organ Prolapse (POP) 549
Chapter 52 Voiding and Urinary Disorders 553
Urinary Incontinence 554
Detrusor Overactivity (DO) 555
Frequency/Urgency Syndrome 556
Simple Urinary Tract Infection (UTI) 557
Recurrent Urinary Tract Infection (UTI) 558
Acute Retention of Urine 559
Microscopic Haematuria (MH) 560
Chapter 53 Vaginal Discharge and Recurrent Vulvovaginal Candidiasis 561
Causes of Vaginal Discharge 561
Management of Vaginal Discharge 562
Treatment of Vaginal Discharge 563
Treatment of Uncomplicated Acute Vulvovaginal Candidiasis (VVC) 564
Treatment of Recurrent Vulvovaginal Candidiasis (VVC) 565
Treatment of Bacterial Vaginosis 566
Treatment of Bacterial Vaginosis in Pregnancy 566
Treatment of Atrophic Vaginitis 567
Treatment of Chlamydia Trachomatis 568
Treatment of Chlamydia Trachomatis Infection in Pregnancy 568
Treatment of Neisseria Gonorrhoea 569
Treatment of Gonococcal Infection in Pregnancy 569
Chapter 54 Pelvic Inflammatory Disease (PID) 571
Chapter 55 Sexually Transmitted Infection (STI) 583
Risk Factors for STI 584
Screening Approach for (STI) 584
Approach to Management of STI 585
Physical Examination 585
STI-related Genital Ulcers 587
Laboratory Investigations for STI 589
Specific STI Investigations and Management 589
1. Genital herpes 589
2. Syphilis 592
3. Chancroid 598
4. Granuloma Inguinale (GI) — Rare 599
5. Lymphogranuloma venerum (LGV) — Rare 600
6. Genital warts 601
7. Human Immunodeficiency Virus (HIV) infection 606
Chapter 56 Oral Hormonal Contraception 613
Combined Oral Contraceptive (COC) Pill 613
Management of Missed Pills for 21-day Regimen — COC 619
Advice to patients for missed pills 620
Progestin Only Pill (POP) 621
Chapter 57 Non-Oral Contraception/Contraception For Lactating Mothers 625
Barrier Method 625
Depot Provera (Progestin-Only Injectables) 626
Evra Patch 627
Implanon Nxt Implants 628
Intrauterine Contraceptive Device (IUCD) 630
Levonorgestrel Intrauterine System (Mirena IUCD) 631
Mesigyna/Norigynon (Monthly Combined Injectables) 633
Nuva Ring 633
Permanent Sterilisation 634
Chapter 58 Choice of Contraception 639
Contraceptive Choice Based on Personal Characteristics and Reproductive History 640
Chapter 59 Contraception in Patients with Medical Conditions and Drug Interactions 647
Combined Hormonal Contraception (CHC) is not recommended in 663
Contraceptive Advice for Women Using Enzyme-inducing Drugs 664
Drugs that increase Contraceptive Hormone Levels 667
Drugs that are affected by Contraceptive Hormones 669
Chapter 60 Intrauterine Contraceptive Device (IUCD) and Associated Dilemmas 673
Missing IUCD Threads 673
Management of Missing IUCD (Intrauterine Contraceptive Device) 675
Other IUCD dilemmas 677
Chapter 61 Emergency Contraception 679
Chapter 62 Menopause 683
Definition 683
Factors Affecting Age of Menopause 684
Clinical Features in Perimenopausal Period 684
Menopausal Transition 685
Long-term Implications 686
Assessment of Menopause 686
Management of Menopause 686
Chapter 63 Osteoporosis 689
Definition 689
Risk Factors for Fractures 690
Screening Assessment Tools 691
OSTA CHART 693
BMD Measurement 694
When to Repeat BMD 695
Management of Osteoporosis 695
Chapter 64 Hormone Replacement Therapy (HRT) 699
WHO to Give? 699
How to Give? 700
Benefits of HRT? 700
Risks of HRT? 700
Contraindications of HRT 701
Selective Oestrogen Receptor Modulators (SERMs) 701
Chapter 65 Subfertility, Semen Analysis and Management of Azoospermia 709
Definition 709
Management of Subfertility 710
Ovarian Hyperstimulation Syndrome (OHSS) 714
Symptoms of OHSS 715
Approach to Azoospermia 724
Chapter 66 Approach to Hyperprolactinaemia 725
Management of Pituitary Adenomas/ Prolactinomas in Pregnancy 729
Chapter 67 Approach to Galactorrhoea 731
History 732
Examination 733
Chapter 68 Sexual Dysfunctional Problems 735
Introduction 735
How to Help Dissatisfied Women with their Sexual Response? 736
History of sexual problem 737
Types of problems encountered 738
The Psychosexual Dysfunction 738
Assessing Categories of Aetiology 740
Physical Examination 740
Investigations 741
Management of Sexual Dysfunction Problems 741
To Treat or to Refer? 742
Intervention 742
Vaginismus 744
Chapter 69 Mammogram, Breast Ultrasound Scan and Breast Biopsy 747
Introduction 747
Mammogram 747
Breast Ultrasound Scan 748
Breast Biopsy 749
Chapter 70 Breast Cancer Screening 751
Screening Mammogram Schedule 751
PART 4: INVESTIGATIONS IN GYNAECOLOGY 753
Chapter 71 Ovarian Tumour Markers 755
Chapter 72 Female Hormonal Profile 759
Chapter 73 Imaging Modalities in Gynaecology 763
Indications for Ultrasound in Gynaecology 763
Indications for Transabdominal Ultrasound Scan 764
1. Transvaginal Ultrasound Scan (TVUS) 764
2. Hysterosalpingography (HSG) 764
3. Saline Infusion Sonohysterography (SIS) 765
4. CT Scan 766
5. MRI Scan 766
Chapter 74 Role of Interventional Radiology (IR) in Obstetrics and Gynaecology 767
Modalities 767
1. Ultrasound Scan (US) 767
2. Computed Tomography (CT Scan) 768
3. Magnetic Resonance Imaging (MRI) Scan 769
General Risks of Procedures 769
Common Procedures Performed at KK Hospital 770
References 793
Index 809