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Fluid and Electrolyte Therapy, An Issue of Veterinary Clinics of North America: Food Animal Practice, E-Book

Fluid and Electrolyte Therapy, An Issue of Veterinary Clinics of North America: Food Animal Practice, E-Book

Geof W. Smith

(2014)

Additional Information

Abstract

Fluid and Electrolyte Therapy, An Issue of Veterinary Clinics of North America: Food Animal Practice, E-Book

Table of Contents

Section Title Page Action Price
Front Cover Cover
Fluid and Electrolyte Therapy\r i
Copyright\r ii
Contributors iii
Contents v
Veterinary Clinics Of North America: Food Animal Practice\r viii
Fluid and Electrolyte Therapy ix
Acid-Base Assessment 295
Key points 295
The Henderson-Hasselbalch equation 296
The strong ion difference approach 298
Three anomalies of the Henderson-Hasselbalch equation 302
Failure to Explain Why an Abnormal Plasma Protein Concentration Changes Plasma pH 302
Failure to Explain Why Ingestion of CaCl2 Is Acidifying 302
Failure to Explain Why the Rapid Intravenous Administration of Large Volume 0.9% NaCl Solution Is Acidifying 303
Application of strong ion difference theory to calves with diarrhea 305
Collection of blood samples to evaluate acid-base status 306
Measurement of total CO2 307
Quantifying the unmeasured anion concentration 307
Anion Gap 307
Strong Ion Gap 308
Urine pH and acid-base balance 308
Summary 309
References 309
Appendix 1 313
d-Lactic Acidosis in Neonatal Ruminants 317
Key points 317
Metabolism of d-lactate 318
Origin of d-lactate in neonatal ruminants 319
Production of d-Lactate in the Reticulorumen 319
Production of d-Lactate in Neonatal Calf Diarrhea 319
Production of d-Lactate in Acidosis Without Dehydration Syndromes 320
Clinical signs of d-lactatemia 321
Pathogenesis of neurologic signs in d-lactatemia 322
Clinical syndromes caused by d-lactic metabolic acidosis in neonatal ruminants 322
d-Lactic Metabolic Acidosis in Ruminal Drinkers 322
Metabolic Acidosis Without Dehydration Syndrome in Suckler Calves 324
d-Lactic Metabolic Acidosis in Neonatal Calf Diarrhea 324
d-Lactic Metabolic Acidosis in Neonatal Small Ruminants 325
Treatment of d-lactic metabolic acidosis 326
Supplementary data 327
References 327
Sodium Balance and the Dysnatremias 333
Key points 333
Introduction 333
Serum sodium concentration and osmolarity 334
Physiologic regulation of ECF osmolarity and volume 335
Water requirements 335
Classification of the dysnatremias 335
Hypernatremia 336
Acute Hypernatremia 336
Case example 337
Iatrogenic acute hypernatremia 339
Spontaneous acute hypernatremia 339
Chronic Hypernatremia 340
Hypernatremia Associated with Persistent Hyperglycemia 340
Hyponatremia 341
Acute Hyponatremia 341
Clinical signs of acute hyponatremia 342
Chronic Hyponatremia 342
Treatment 343
Fluid Therapy for Acute Hypernatremia (<48 hours) 343
Fluid Therapy for Chronic Hypernatremia 345
Fluid Therapy for the Hyperosmolar Syndrome in Crias 346
Acute Hyponatremia (<48 hours) 346
Chronic Hyponatremia (﹥48 hours) 346
Prevention 347
References 347
Hypokalemia Syndrome in Cattle 351
Key points 351
Introduction 351
Normal potassium balance 351
The clinical syndrome 352
Introduction 352
Risk Factors 352
Clinical Signs 353
Pathophysiology 354
Differential Diagnosis 354
Clinical Pathology and Ancillary Tests 355
Treatment 355
Nonspecific treatment 355
Specific treatment 355
Prevention 356
Prognosis 356
Unanswered questions 356
References 356
Calcium and Magnesium Disorders 359
Key points 359
Impact of hypocalcemia on cow health 359
Ca homeostasis 360
Ca Pools Within the Body 360
Role of Parathyroid Hormone 360
Renal Ca Reabsorption 361
Osteoclastic Bone Ca Resorption 362
Osteocytic Osteolysis of Bone Ca 363
Dietary Ca Absorption 363
Vitamin D–Dependent Transcellular-Intestinal Absorption 363
Paracellular Intestinal Ca Absorption 364
Why does Ca homeostasis fail in some cows? 365
High DCAD 365
Application of DCAD Theory to Reduce Periparturient Hypocalcemia 367
Desired Mineral Profile of Prepartum Diet 367
Na 367
Ca 367
Mg 368
P 368
S 368
K and Cl 368
Monitoring Urine pH 369
Agronomic Considerations for Producing Low DCAD Forages 370
Hypomagnesemia 370
Feeding a low-Ca diet before calving to prevent hypocalcemia 371
Vitamin D supplementation 372
Oral Ca treatments at calving 372
Age 373
Breed 373
Summary of Hypocalcemia Avoidance Measures 373
Mg 374
Body Content and Distribution of Mg 374
Factors Affecting the Soluble Mg Content in the Rumen 374
Factors Affecting Active Transport of Mg Across the Rumen 375
Using Other Transport Mechanisms to Absorb Dietary Mg 375
Assessing Mg Status at Parturition 375
Assessing Availability of Mg from Mineral Sources 376
References 376
Treatment of Phosphorus Balance Disorders 383
Key points 383
Functions of phosphorus in the organism 383
Phosphorus, Inorganic Phosphorus, and Phosphate 384
Distribution of Phosphorus in the Body 384
Phosphorus homeostasis and homeorhesis 385
Regulation of Phosphorus Homeostasis 387
Assessment of Phosphorus Status 387
Phosphorus concentration in serum or plasma 388
Phosphorus concentration in whole blood or in red blood cells 388
Phosphorus concentration in saliva 388
Phosphorus concentration in urine 388
Phosphorus concentration in feces or rumen fluid 389
Bone phosphorus content 389
Soft tissue phosphorus content 389
Serum Phosphorus Concentration 389
Site of blood sample collection 390
Anticoagulants 390
Sample collection and sample processing 390
Presample collection factors 390
Hypophosphatemia 390
Mechanisms of Hypophosphatemia 390
Hypophosphatemia due to inadequate dietary P supply 391
Hypophosphatemia due to excessive P losses 391
Hypophosphatemia due to compartmental P shifts 391
Hypophosphatemia due to a combination of several mechanisms 392
Occurrence of Hypophosphatemia 392
Clinical Signs Associated with Hypophosphatemia 393
Treatment Indication 394
Treatment of Hypophosphatemia 395
Parenteral Treatment 395
Compounds for parenteral phosphate supplementation 395
Dosage recommendations 396
Infusion rate 397
Recommendations for parenteral treatment 397
Oral Treatment 398
Hyperphosphatemia 399
Phosphorus Toxicity and Hyperphosphatemia 399
Clinical Signs of Hyperphosphatemia 400
Treatment of Hyperphosphatemia 401
References 401
Fluid Therapy in Calves 409
Key points 409
Oral electrolyte therapy 410
Sodium Concentration 412
Chloride Concentration 412
Potassium Concentration 412
Sodium Absorption 412
Osmolality 413
Alkalinizing Ability 414
Administration of oral electrolyte solutions 416
Summary 417
IV fluid therapy 418
Assessing the Need for IV Fluid Therapy 418
Solutions for IV Administration 419
Lactated Ringer solution 419
Acetated Ringer solution 419
Isotonic sodium bicarbonate 419
Hypertonic saline 420
Hypertonic sodium bicarbonate 420
Dextrose 421
Administration of IV fluids 421
A Simplified Protocol for On-farm IV Fluid Therapy 422
References 424
Fluid Therapy in Mature Cattle 429
Key points 429
Introduction 429
What is the problem? 430
Dehydration 430
Acidosis or Alkalosis? 430
Electrolyte Abnormalities 431
What do I administer to correct the problem? 431
Dehydration 431
Acid-Base Balance and Electrolytes 432
How much do I administer? 433
Volume 433
Correcting Acidosis 434
Electrolytes 435
By what route do I administer the solutions and at what rate? 435
Techniques for Administration 436
References 438
Fluid Therapy in Small Ruminants and Camelids 441
Key points 441
Introduction 441
Patient evaluation 442
Hydration Deficit 442
Electrolyte and Acid-Base Alterations 442
Fluid Administration 442
Route 442
Volume and rate 443
Replacement of hydration deficit 443
Maintenance fluid requirement 443
Ongoing losses 444
Fluid type 444
Crystalloid Solutions 444
Hypertonic Solutions 446
Hypotonic Solutions 446
Acidifying Solutions 446
Alkalinizing Solutions 446
Dextrose Solutions 447
Colloidal Solutions 449
Orally Administered Solutions 449
Parenteral nutrition 450
References 452
Update on the Use of Blood and Blood Products in Ruminants 455
Key points 455
Introduction 455
Normal hematologic values for ruminants 456
Whole blood 457
Indications 457
Contraindications 458
Duration of Benefit 458
Quantity Required 458
Donor Selection 459
Blood groups/types 459
Biosecurity and disease transmission 459
Autotransfusion 460
Collection Technique 461
Anticoagulants 461
Commercial blood collection kits 462
Storage 463
Administration 465
Adverse Reactions 466
Blood components 467
Plasma 467
Indications 467
Testing 467
Benefits 467
Collection technique and commercial sources 468
Technique 468
Adverse reactions 469
Fractionated Blood Products 469
pRBC 469
PRP 469
Hyperimmune serum 470
Synthetic Blood Products 470
Summary 470
References 471
Index 475