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PET/CT Imaging in Tracers Beyond FDG, An Issue of PET Clinics, E-Book

PET/CT Imaging in Tracers Beyond FDG, An Issue of PET Clinics, E-Book

Mohsen Beheshti

(2014)

Additional Information

Abstract

This issue of PET Clinics examines PET/CT Imaging in Tracers Beyond FDG. Article include standardization and quantification in PET/CT imaging: tracers beyond FDG; 18F NaF PET/CT imaging; 18F NaF PET/CT imaging in pediatrics; choline PET/CT imaging for the head and neck, thorax, abdomen, and pelvis; DOPA PET/CT imaging for the head and neck, thorax, abdomen, and pelvis; 68 GaSSRTs PET/CT imaging for the head and neck, thorax, abdomen, and pelvis; FLT PET/CT imaging for the head and neck, thorax, abdomen, and pelvis; hypoxia tracers; PET/MRI tracers beyond FDG: current status and future aspects; PET/CT normal variations: effect of novel quantitative approaches; and more!

Table of Contents

Section Title Page Action Price
Front Cover Cover
PET/CT Imaging in Tracers Beyond FDG: Normal Variations and Benign Findings\r i
Copyright\r ii
Contributors iii
Contents v
Pet Clinics\r viii
Preface\r xi
Standardization and Quantification in PET/CT Imaging 259
Key points 259
Introduction 259
Standardization programs running in 2014 259
Examples of 2 nonstandard procedures using carbon-11 radiopharmaceuticals 261
MET 261
Patient Preparation 263
Administered Activity 263
Image Interpretation 263
Normal biodistribution 263
Pathologic findings 263
CHO 264
Patient Preparation 264
Administered Activity 264
Image Interpretation 264
Normal biodistribution 264
Pathologic findings 264
Summary 265
References 265
Brain 267
Key points 267
Introduction 267
Dementia 267
Epilepsy 270
Movement disorders 270
Brain tumors 272
Neuroinflammation 273
Summary 274
References 274
18F-Fluoride PET/Computed Tomography Imaging 277
Key points 277
Introduction 277
Mechanism of uptake of 18F-fluoride in bone: which bone lesions accumulate 18F-fluoride? 277
18F-fluoride PET/CT imaging technique 278
Radiation exposure of 18F-fluoride PET/CT 278
Normal distribution of 18F-fluoride 278
Benign indications for 18F-fluoride PET imaging 279
Summary 283
References 283
18F-Fluoride PET and PET/CT in Children and Young Adults 287
Key points 287
Technical procedures 287
Clinical indications for 18F-fluoride PET/CT 288
Back Pain in Children, Adolescents, and Young Adults 288
Scoliosis and Spinal Surgery 292
Benign Bone Lesions 292
Quantitative Bone Metabolism 293
Bone Viability 293
Skeletal Injury in Child Abuse 294
Cancer Imaging 295
Summary 296
References 296
Fluorocholine PET/Computed Tomography 299
Key points 299
Introduction 299
Central nervous system/head and neck 300
Thorax 301
Abdomen 301
Pelvis (including the genitourinary system) 303
Effect of drugs 304
Summary 305
References 305
18F-DOPA PET/Computed Tomography Imaging 307
Key points 307
Introduction 307
The radiopharmaceutical 307
Main clinical applications of 18F-DOPA PET/CT 308
Imaging the Striatum 308
Imaging Brain Tumors 308
Imaging Neuroendrocrine Tumors 308
Imaging (Congenital) Hyperinsulinemic Hypoglycemia 309
18F-DOPA PET/CT acquisition protocol 309
Carbidopa Pretreatment 309
Preparation 309
Dose and Timing 309
Acquisition 310
Normal biodistribution of whole-body 18F-DOPA PET/CT 310
Effect of carbidopa premedication on the biodistribution of 18F-DOPA 311
Image Interpretation 311
Head and neck 312
Thorax 313
Abdomen and pelvis 313
Possible pitfalls 314
Pitfalls Related to the Interpretation of PET and PET/CT Images 314
Gallbladder/Common bile duct 315
Urinary excretion tract 315
Pancreas 315
Pitfalls Related to Pathology 316
Technical Pitfalls 318
Summary 319
Acknowledgments 319
References 319
The Use of Gallium-68 Labeled Somatostatin Receptors in PET/CT Imaging 323
Key points 323
Introduction 323
Clinical Background 323
68Ga-DOTA-SSTRTs PET/CT Imaging 325
Effects of treatment on 68Ga-DOTA-peptides uptake 327
Effects of aging on 68Ga-DOTA-peptides uptake 327
Physiologic uptake, benign findings, and pitfalls 327
Summary 327
References 328
Proliferation Imaging with 18F-Fluorothymidine PET/Computed Tomography 331
Key points 331
Introduction 331
Applications of 18F-FLT in the clinic 332
Head and neck 332
Thorax 334
Abdomen 334
Pelvis and genitourinary system 335
Effects of aging and treatment 335
Aging 335
Treatment-Induced Effects 335
Summary 336
References 336
11C-Acetate PET/CT Imaging 339
Key points 339
Central nervous system, head, and neck 340
Thorax 340
Abdomen 341
Pelvis 342
References 343
PET/MRI Radiotracer Beyond 18F-FDG 345
Key points 345
Introduction 345
Fluorine-18 choline/carbon-11 choline 345
Gallium 68–tetraazacyclododecane tetraacetic acid–octreotate compounds 346
Fluorine-18–sodium fluoride 346
Fluorine-18–labeled dihydroxyphenylalanine 347
Fluorine-18–flutemetamol 347
Fluorine-18–fluoromisonidazole 347
Cardiovascular molecular imaging applications 347
References 348
Index 351