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Breast Imaging, An Issue of Radiologic Clinics of North America, E-Book

Breast Imaging, An Issue of Radiologic Clinics of North America, E-Book

Christopher E. Comstock | Cecilia L. Mercado

(2014)

Additional Information

Book Details

Abstract

Guest edited by Christopher Comstock of Memorial Sloan-Kettering, this issue of Radiologic Clinics will provide all of the latest guidelines and techniques for breast imaging. Modalities include MRI, MR-CAD, digital tomosynthesis, and ultrasound.

Table of Contents

Section Title Page Action Price
Front Cover Cover
Breast Imaging i
copyright\r ii
Contributors iii
Contents v
Radiologic Clinics Of North America\r ix
Preface xi
Screening Mammography Benefit Controversies 455
Key points 455
Randomized trials have proven that early detection reduces breast cancer death rates 456
Results of RCTs 456
Origins of the Controversy Regarding Women Aged 40 to 49 Years 458
Mortality Reduction Among Women Screened in Their 40s 459
Screening Women 75 Years of Age and Older 459
Why Do Randomized Trials Underestimate the Benefit from Screening? 460
Validity of RCT Results: the Gotzsche and Olsen Controversy 461
Service screening studies 463
IBM Studies 463
Case-Control Studies 464
Trend Studies 465
Can modern treatment substitute for early detection? 465
The overdiagnosis controversy 467
Was there Overdiagnosis in RCTs? 467
How Frequent was Overdiagnosis in Service Screening Studies? 467
What Length of Follow-Up Is Needed for an Accurate Estimate of Overdiagnosis? 467
Use of Trend Studies to Estimate Overdiagnosis 468
Is ductal carcinoma in situ a real cancer? 469
How frequently should women be screened? 470
Mathematical Models 470
Clinical Observational Studies 471
USPSTF Controversy 471
Absolute and Relative Benefit 472
Benefits and Costs 473
Summary 474
References 474
BI-RADS Update 481
Key points 481
Introduction 481
Breast imaging lexicon 481
Mammography Lexicon 481
Ultrasound Lexicon 482
Magnetic Resonance Imaging Lexicon 482
Reporting system 483
Auditing 485
Assessment categories 485
Summary 486
Addendum 486
References 486
Digital Tomosynthesis 489
Key points 489
Introduction 489
Image acquisition 489
Geometry 489
Step-and-shoot Versus Continuous Gantry Motion 490
Scan Angle, Angular Sampling, and Number of Projections 490
Scatter 491
Technique Selection (Tube Voltage, Tube Current, and Target-Filter Combination) 491
Reconstruction techniques 491
Filtered Backprojection 491
Iterative Techniques 492
Artifacts 493
Spatial Resolution 493
Comparison with Breast CT 494
Dose and dose optimization 495
Summary 495
References 496
Clinical Implementation of Digital Breast Tomosynthesis 499
Key points 499
Introduction 499
Why digital breast tomosynthesis? 499
Summary of DBT data 500
DBT in Screening 500
Screening DBT: One View Versus Two Views 501
Tomosynthesis Performance Versus Breast Density 502
Tomosynthesis in Diagnostic Imaging 503
Calcifications with DBT 509
Basics of DBT interpretation 510
What Is in a DBT Image Set? 510
Tools for DBT Interpretation 510
Triangulation 510
Slabbing 510
How to Incorporate the DBT Images into Hanging Protocols 511
Considerations in DBT implementation 511
Dose Concerns 511
CAD in DBT 513
Interpretation Time 514
Image Storage Issues 515
Learning Curve and DBT Training 515
Reimbursement 515
Summary 515
References 516
High-quality Breast Ultrasonography 519
Key points 519
Introduction 519
Patient positioning 519
Transducer selection 520
Image resolution 520
Focal zone 520
Depth 521
Gain and time gain compensation 521
Spatial compound imaging 521
Harmonic imaging 522
Color Doppler and power Doppler 522
Real-time imaging 522
Targeted ultrasound: lesion correlation 523
American College of Radiology accreditation 524
Summary 525
References 525
Update on Screening Breast Ultrasonography 527
Key points 527
Current recommendations for screening breast ultrasonography 527
Review of the literature on screening whole-breast ultrasonography 528
Handheld Screening Whole-Breast Ultrasonography 528
Ultrasonography Screening Methods: Handheld Versus Automated Whole-breast Ultrasonography 530
Supplemental Screening Ultrasonography Versus Supplemental Screening MR Imaging 532
Factors influencing the implementation of screening breast ultrasonography 533
High Rate of False-positives 533
Probably Benign Findings Requiring Short-interval Follow-up 533
Certification and Accreditation for Screening Breast Ultrasonography 534
Political and Economic Factors 534
Summary 535
References 535
Automated Whole Breast Ultrasound 539
Key points 539
History 539
Equipment/Systems 540
Technology 543
Clinical use/workflow 543
References 546
High-Quality Breast MRI 547
Key points 547
Introduction 547
Equipment requirements 548
Adequate Magnetic Field Strength and Homogeneity 548
A Bilateral Breast Coil with Prone Positioning 549
Adequate Magnetic Field Gradients 550
Good Fat Suppression Over Both Breasts 551
Pulse sequence requirements 551
Gd-chelate Contrast Agent Administration: 0.1 mmol/kg Followed by 20 mL of Saline 554
Bilateral Acquisition with Prone Positioning 555
A 3D Fourier Transform Gradient-Echo T1-Weighted Pulse Sequence 556
Adequately Thin Slices of 3 mm or Less 556
Pixel Sizes of Less than 1 mm in Each In-Plane Direction 556
Phase-Encoding Direction Chosen to Minimize Artifacts Across the Breasts 556
Total 3DFT Acquisition Time for Each Series of 1 to 3 Minutes 558
Adequate SNR to Visualize Small Enhancing Vessels on 3D Maximum Intensity Projection Images 560
The ACR Breast MRI Accreditation Program 560
Summary 561
References 561
Approach to Breast Magnetic Resonance Imaging Interpretation 563
Key points 563
Introduction 563
Before the examination 564
Current Indications for Breast MR Imaging 564
Patient Information Gathering 564
Examination acquisition 565
Equipment and Positioning 565
Imaging Parameters 567
Postprocessing 567
Interpretation process 568
Global Approach: Fibroglandular Volume and BPE 569
Focal Approach: Morphology and Kinetic Assessment 572
Morphologic Assessment 572
Kinetic Assessment 573
Additional Findings 576
Reporting 577
Summary 580
References 580
Breast Magnetic Resonance Imaging 585
Key points 585
Introduction 585
Clinical significance of an enhancing focus 585
Characteristics of foci: examination indication 586
Characteristics of foci: kinetic analysis 586
Characteristics of foci: T2-weighted signal intensity 587
Characteristics of foci: size 588
Characteristics of foci: interval change and number 588
Summary 588
References 588
MR Evaluation of Breast Implants 591
Key points 591
Introduction 591
Evaluation of Implant Integrity 591
Relationship to Breast Lesions 592
Soft-Tissue (Extracapsular) Silicone 592
Implant Volume 593
Determination of Implant Type and Manufacturer 593
Normal breast MR imaging appearances and imaging technique 593
Mammography, Ultrasound, and CT Imaging 594
MR Imaging 594
Silicone molecular structure 595
Anatomy 595
Parameter settings in breast implant MR imaging 596
Extracapsular silicone 596
Intracapsular silicone 596
Breast implant MR imaging pulse sequences 597
MR image acquisition hints and pitfalls 598
Normal MR imaging appearance and variants of silicone gel–filled breast implants 600
Single lumen 600
Standard double-lumen 601
Gel-gel double lumen 601
Reverse double-lumen expander-implant 601
Abnormal imaging findings 601
Diagnosis of Rupture 601
Diagnosis of Deflation 603
Diagnosis of Soft Tissue Silicone 604
Differential Diagnosis 604
Additional Pearls, Pitfalls, and Variants 605
What the Referring Physician Needs to Know 606
Summary 606
References 607
Contrast-Enhanced Digital Mammography 609
Key points 609
Contrast-enhanced mammography 609
Digital subtraction angiography 610
Temporal technique 610
Contrast-enhanced dual-energy digital mammography 611
Summary 615
References 615
Index 617