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African Skin and Hair Disorders, An Issue of Dermatologic Clinics, E-Book

African Skin and Hair Disorders, An Issue of Dermatologic Clinics, E-Book

Nonhlanhla P Khumalo

(2014)

Additional Information

Abstract

People of African ancestry have sensitive skin and may suffer from a wide variety of skin disorders. Hair disorders are also common and differ from those suffered by Caucasians. This issue of the Dermatologic Clinics focuses on the most common skin and hair disorders seen in black skin, with articles focusing on acne scarring, alopecia, keloids, and skin pigmentation. There are also articles addressing moisturizers for the skin and the effect of hair treatments on the hair and scalp. Also discussed is the sociohistoric issues that can cloud the scientific understanding of clinical entities. Emphasis is often put on race and yet a very clear distinction should be made between race and quantifiable entities such as pigment and hair curl as determinants for skin/hair disease predilection; this is quite distinct from race as a surrogate for social class and a disease determinant for most medical conditions and malignancies.

Table of Contents

Section Title Page Action Price
Front Cover Cover
African Skin and\rHair Disorders i
copyright\r ii
Contributors iii
Contents v
Dermatologic Clinics\r viii
Preface\r ix
References xi
The Evolution of Skin Pigmentation and Hair Texture in People of African Ancestry 113
Key points 113
Diversity of integumentary phenotypes within Africa 113
The influence of natural selection on integumentary phenotypes 114
Integumentary phenotypes and race 118
Summary 118
Acknowledgments 119
References 119
What’s New in Objective Assessment and Treatment of Facial Hyperpigmentation? 123
Key points 123
Introduction 123
Objective assessment—melasma 123
Clinical Findings 123
Severity Scales 123
Pharmacologic treatment options: melasma 124
Combination Therapies 125
Surgical Treatments 125
Summary 127
Objective assessment-PIH 127
Pharmacologic treatment options (PIH) 128
Nonpharmacologic Treatment Options 128
Combination Therapies 129
Surgical Treatment Options 129
Summary/Discussion 129
Pharmacologic treatment options (DPN and seborrheic keratosis) 130
Surgical Treatment Options 130
Pharmacologic treatment options (lichen planus pigmentosus/EDP of face) 132
Combination Therapies 132
Surgical Therapies 132
References 133
Cosmeceuticals 137
Key points 137
Introduction 137
Cosmeceuticals and the Regulatory Environment 137
Development of Scientific Substantiation 138
Cosmeceutical Development 139
Cosmeceutical Claims 139
Mechanism of Action for Cosmeceuticals 140
Barrier function 140
Photoprotection 140
Pigment lightening 140
Receptor activation 141
Peptide cellular messengers 141
Antioxidants 141
Cosmeceuticals and Skin Tone 141
Summary: the future 142
References 142
A Systematic Approach to Afro-Textured Hair Disorders 145
Key points 145
Introduction 145
Normal scalp 145
Tinea capitis 146
Alopecia areata 147
Alopecia due to hair breakage 147
Androgenetic alopecia 147
CCCA 148
Traction alopecia 148
Discoid lupus erythematosus 148
LPP 149
Frontal fibrosing alopecia 149
Dissecting cellulitis of the scalp 149
Pili annulati 149
When to biopsy 150
Summary 150
References 150
Traction Alopecia 153
Key points 153
Introduction 153
Clinical presentation 154
Histology 155
Differential diagnosis of marginal traction alopecia 155
Disease prevalence 155
Clinical tools for quantifying disease severity 156
Risk factors for TA 156
Hair Care Practices 156
Hair Type 157
Genetic Factors 158
Hairdressing Symptoms 158
Age 158
Gender 158
Treatment options 158
Public education strategies 159
Summary 160
References 160
Advances and Challenges in Hair Restoration of Curly Afrocentric Hair 163
Key points 163
Introduction 163
Candidate selection 164
Major considerations/differences 164
The test transplant 164
Anesthesia 166
Donor harvesting 166
Graft creation 167
Hairline design 167
Recipient site creation 168
Graft placement 168
Postoperative care 169
Future trends 169
Summary 170
References 170
Central Centrifugal Cicatricial Alopecia 173
Key points 173
Introduction 173
Hair morphology 173
Hair care practices 174
Methods of Straightening 174
Styling 174
Hair Cleansing 175
History of CCCA 175
Clinical features 176
Histopathology 177
Epidemiology 177
Cause 178
Hair Care Practices 178
Female Pattern Hair Loss 178
The Role of Chronic Inflammation and Microorganisms 178
Family History 179
Treatment 179
Current clues for future research 179
References 180
Folliculitis Keloidalis Nuchae and Pseudofolliculitis Barbae 183
Key points 183
Introduction 183
Pseudofolliculitis barbae 183
Epidemiology 183
Pathogenesis 184
Clinical Features 184
Management 185
Folliculitis keloidalis nuchae 187
Epidemiology 187
Pathogenesis 188
Clinical Features 188
Management 189
Summary 189
References 189
New Insights on Keloids, Hypertrophic Scars, and Striae 193
Key points 193
Introduction 193
Patient evaluation overview 195
Management goals 196
Pharmacologic treatment options 197
Intralesional Injections 197
Tretinoin 199
Acid Peels 199
Nonpharmacologic treatment options 199
Silicone Gel 199
Cryotherapy 200
Topical Oils/Creams 200
Light Therapy 201
Electrical Stimulation 201
Lasers 201
Combination therapies 202
Self-management strategies 202
Surgical treatment options and procedure 203
Treatment resistance 204
Evaluation of outcome and long-term recommendations 204
Summary 204
References 205
The Spectrum of HIV-Associated Infective and Inflammatory Dermatoses in Pigmented Skin 211
Key points 211
Introduction 211
Viral infections 212
Herpes Simplex Virus Infection 212
Molluscum Contagiosum 212
Herpes Zoster 212
Viral Warts 213
Baterial infections 213
Staphylococcus aureus Infection 213
Bacillary Angiomatosis 213
Syphilis 213
Cutaneous Tuberculosis 214
Fungal infections 215
Dermatophytes 215
Deep Fungal Infections 215
Parasitic infestations 216
Inflammatory dermatoses 217
Seborrheic Dermatitis 217
Psoriasis 218
Reiter Syndrome 219
Pruritic Papular Eruption 220
Eosinophilic Folliculitis 220
Xerosis 221
Photosensitivity Disorders 221
Summary 222
References 222
Clinical Presentations of Severe Cutaneous Drug Reactions in HIV-Infected Africans 227
Key points 227
Introduction 227
Epidemiology of HIV-associated CADRs in Africa 227
Pharmacogenetics of CADRs in Africa 228
Types of CADRs 228
Morbiliform Drug Eruptions 228
Drug Rash with Eosinophilia and Systemic Symptoms 228
Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis 229
Lichenoid Drug Reactions 230
Fixed Drug Eruptions 231
Efavirenz-associated CADRs 231
Special considerations in HIV-associated CADRs 231
Multiple Drug Hypersensitivity Reactions 231
Immune Reconstitution Inflammatory Syndrome 232
Systemic Reactions to Patch Tests and Skin Prick Tests 232
CADRs in Pregnancy 232
SJS and TEN-associated Anxiety and Depression 232
Summary 232
References 233
Infective Dermatitis Associated with HTLV-1 Mimics Common Eczemas in Children and May Be a Prelude to Severe Systemic Diseases 237
Key points 237
Introduction 237
The origins of HTLV-1 237
Geographic subtypes 238
HTLV-1 transmission 238
Clinical characteristics of HTLV-1 infection 238
Diagnosis of HTLV-1 infection 239
Immune control of HTLV-1 infection 239
IDH 239
Clinical findings 240
Differential diagnosis 241
Pathologic and immunohistochemical findings 242
Disease evolution 242
Pathogenesis 244
Treatment and prevention of complications 245
Summary 245
References 245
Index 249