BOOK
Clinical Approaches to Oral Mucosal Disorders: Part II, An Issue of Dental Clinics of North America, E-Book
(2014)
Additional Information
Book Details
Abstract
Part II of our important volume on oral mucosal disorders, in this issue we cover: oral herpes virus infections, recurrent aphthous stomatitis, lichen planus/lichenoid mucositis, pediatric soft tissue diagnosis, oral cancer, chemotherapy/radiation induced oral mucositis, bisphosphonate related osteonecrosis of jaws/anti-resorptive drug related osteonecrosis of the jaw, oral graft-versus-host disease, human papillomavirus, perioral lesions and dermatoses, and more!
Table of Contents
Section Title | Page | Action | Price |
---|---|---|---|
Front Cover | Cover | ||
Clinical Approaches to Oral Mucosal Disorders: Part II\r | i | ||
copyright\r | ii | ||
Contributors | iii | ||
Contents | vii | ||
Dental Clinics Of North America\r | x | ||
Preface | xi | ||
Dedication | xi | ||
Update on Oral Herpes Virus Infections | 265 | ||
Key points | 265 | ||
Introduction | 265 | ||
HSV | 266 | ||
Primary herpes simplex infections | 266 | ||
Recurrent herpes simplex infection | 267 | ||
Diagnosis | 270 | ||
Differential Diagnosis | 270 | ||
Laboratory Diagnosis | 271 | ||
Virologic tests | 271 | ||
Cytology smears | 271 | ||
Immunomorphologic tests | 271 | ||
Polymerase chain reaction test | 271 | ||
Serologic tests | 271 | ||
VZV | 272 | ||
Varicella | 272 | ||
HZ | 272 | ||
EBV | 273 | ||
CMV | 274 | ||
HHV-6 | 275 | ||
HHV-7 | 275 | ||
HHV-8 | 276 | ||
Summary | 276 | ||
References | 276 | ||
Recurrent Aphthous Stomatitis | 281 | ||
Key points | 281 | ||
Introduction | 281 | ||
Epidemiology | 282 | ||
Predisposing etiologic factors | 282 | ||
Local Factors | 283 | ||
Microbial Factors | 284 | ||
Underlying Disease | 285 | ||
Hereditary and Genetic Factors | 286 | ||
Allergic Factors | 287 | ||
Immunologic Factors | 287 | ||
Nutritional Factors | 288 | ||
Psychological Stress | 288 | ||
Other Factors | 288 | ||
Clinical manifestation and pathogenesis | 289 | ||
Management | 289 | ||
Summary | 292 | ||
References | 292 | ||
Oral Lichen Planus and Lichenoid Mucositis | 299 | ||
Key points | 299 | ||
Introduction | 299 | ||
Nature of Problem and Definition | 299 | ||
Prevalence/Incidence | 300 | ||
Cause and Pathogenesis | 300 | ||
Symptoms | 301 | ||
Clinical findings | 302 | ||
Physical Examination | 302 | ||
Diagnostic Modalities | 304 | ||
Pathology | 304 | ||
Diagnostic dilemma: a premalignant lesion | 305 | ||
Comorbidities | 306 | ||
Lichenoid Drug Reactions | 306 | ||
Hepatitis C and OLP | 307 | ||
Management | 307 | ||
Goals | 307 | ||
Pharmacologic Strategies: Topical Medications | 308 | ||
Pharmacologic Strategies: Systemic Therapies | 308 | ||
Summary | 310 | ||
References | 310 | ||
Oral Cancer | 315 | ||
Key points | 315 | ||
Anatomic sites | 317 | ||
Stage at diagnosis and survival | 319 | ||
TNM staging | 319 | ||
Cause and risk factors | 320 | ||
Immune system | 320 | ||
Tobacco | 320 | ||
Oral lichen planus | 321 | ||
Nutrition | 321 | ||
Viruses | 321 | ||
Clinical assessment | 322 | ||
Signs and symptoms | 322 | ||
Erythroleukoplakia and erythroplakia | 325 | ||
Erythroplakia with ulceration | 325 | ||
PVL | 325 | ||
Candidiasis (candidosis), leukoplakia, and erythroplakia | 325 | ||
Delay in diagnosis | 326 | ||
Oral carcinogenesis, epithelial dysplasia, and malignant transformation | 327 | ||
Molecular progression | 328 | ||
Genomics and proteomics | 328 | ||
Precancerous classification (PMDs) | 329 | ||
Diagnosis and management | 330 | ||
Incisional and excisional scalpel or punch biopsy | 330 | ||
Diagnostic adjunctive techniques | 330 | ||
Cytology and brush biopsy | 330 | ||
Fine-needle aspiration | 331 | ||
Toluidine blue | 331 | ||
Visualization-based adjunctive techniques | 331 | ||
Monoclonal antibodies | 332 | ||
Imaging | 332 | ||
Chemoprevention | 333 | ||
Chemoprevention of Oral Leukoplakia Remains Experimental | 333 | ||
Workup for patients with oral SCCs | 333 | ||
Treatment | 333 | ||
Follow-up | 334 | ||
References | 334 | ||
Chemotherapy or Radiation-Induced Oral Mucositis | 341 | ||
Key points | 341 | ||
Introduction, epidemiology, and pathogenesis | 341 | ||
Morbidity of oral mucositis | 342 | ||
Pain | 342 | ||
Nutritional Compromise | 342 | ||
Quality of Life | 342 | ||
Impact on Cancer Therapy | 342 | ||
Infection | 342 | ||
Impact on Oral Health | 344 | ||
Economic Impact | 344 | ||
Clinical findings | 344 | ||
Management of oral mucositis | 345 | ||
Symptom Management | 345 | ||
Targeted Therapeutic Interventions | 346 | ||
Cryotherapy | 346 | ||
Low-level laser therapy | 347 | ||
Growth factors | 347 | ||
Antiinflammatory agents | 347 | ||
Antimicrobial agents | 347 | ||
Summary | 348 | ||
References | 348 | ||
Oral Graft-Versus-Host Disease | 351 | ||
Key points | 351 | ||
Introduction | 351 | ||
Pathobiology and incidence of GVHD | 352 | ||
aGVHD | 353 | ||
cGVHD | 354 | ||
Oral GVHD | 355 | ||
Incidence | 355 | ||
Clinical Findings | 355 | ||
Diagnosis and Assessment | 356 | ||
Impact of GVHD | 358 | ||
Overall Survival | 358 | ||
Quality of Life | 359 | ||
Oral GVHD | 359 | ||
Prevention and management of GVHD | 359 | ||
Management Principles | 359 | ||
Prophylaxis | 360 | ||
Systemic Therapy | 360 | ||
Management of oral GVHD | 361 | ||
Pharmacologic Strategies | 361 | ||
Nonpharmacologic Strategies | 362 | ||
Late complications of oral GVHD | 363 | ||
Summary | 363 | ||
References | 364 | ||
Antiresorptive Drug–Related Osteonecrosis of the Jaw | 369 | ||
Key points | 369 | ||
Introduction | 369 | ||
Antiresorptive Drugs Associated with ONJ | 370 | ||
BP | 370 | ||
Anti-RANK ligand: denosumab | 370 | ||
Differences between BP and denosumab | 371 | ||
Epidemiology | 371 | ||
Worldwide incidence | 372 | ||
Clinical parameters | 373 | ||
Diagnostic Guidelines and Staging of ARONJ | 373 | ||
Imaging | 373 | ||
Pathogenicity | 374 | ||
Impaired Epithelial Repair | 374 | ||
Bacterial Colonization and Biofilm | 375 | ||
Immunosuppression | 375 | ||
Diagnostic dilemmas | 376 | ||
Management strategies | 377 | ||
Surgical Strategies | 377 | ||
Nonsurgical and Adjunctive Strategies | 379 | ||
Summary | 379 | ||
References | 380 | ||
The Role of Human Papillomavirus in Oral Disease | 385 | ||
Key points | 385 | ||
Introduction | 385 | ||
The virus | 386 | ||
HPV infection | 387 | ||
HPV immunology | 388 | ||
HPV transmission | 388 | ||
Epidemiology | 388 | ||
Oral clinical lesions associated with HPV | 389 | ||
Verruca Vulgaris (Common Wart) | 389 | ||
Multifocal Epithelial Hyperplasia (Heck Disease) | 390 | ||
Condyloma Accuminatum (Venereal Wart) | 390 | ||
Oral squamous papilloma | 392 | ||
Potentially malignant papillomatous lesions | 392 | ||
Oral leukoplakia and head and neck squamous cell carcinoma | 392 | ||
Treatment of oral HPV-related clinical lesions | 394 | ||
Prevention | 395 | ||
Summary | 395 | ||
Acknowledgments | 396 | ||
References | 396 | ||
Perioral Lesions and Dermatoses | 401 | ||
Key points | 401 | ||
Index | 455 |