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Oncologic Ultrasound, An Issue of Ultrasound Clinics, E-Book

Oncologic Ultrasound, An Issue of Ultrasound Clinics, E-Book

Vikram S. Dogra

(2014)

Additional Information

Abstract

The detection of tumors in various organ systems remains one of the central applications of ultrasound. This issue of Ultrasound Clinics will consist of 10 articles under the title “Oncologic Ultrasound” and will feature several articles on elastrography (a developing method for distinguishing tumors from normal tissue), as well as endoscopic ultrasound in oncology, ultrasound guidance in tumor ablation, and ultrasound guided biopsies. The editor, Vikram Dogra, who also serves as consulting editor of the series, has put together an issue that addresses the core clinical concerns of oncologic imaging for the radiologist specializing in ultrasound.

Table of Contents

Section Title Page Action Price
Front Cover Cover
Oncologic Ultrasound\r i
Copyright\r ii
Contributors iii
Contents v
Ultrasound Clinics\r viii
Preface xi
Elastography 1
Key points 1
Introduction 1
The physics of elastography 1
Approaches to elastography 3
Quasistatic Elastography 3
Harmonic Elastography Based on Local Frequency Estimation 5
Transient Elastography Based on Arrival Time Estimation 6
The future of elastography 7
Viscoelasticity 7
Nonlinearity 8
References 8
Elastography of Thyroid Masses 13
Key points 13
Discussion of problem/clinical presentation 13
Imaging protocols 13
Imaging Findings 13
Quasi-static or strain elastography or sonoelastography 13
Acoustic radiation force imaging 15
Shear wave elastography 15
Pearls, pitfalls, and variants 16
What the referring physician needs to know 19
Summary 22
References 22
The Special Contribution of Contrast-Enhanced Ultrasound to Oncology 25
Key points 25
Preamble 25
CEUS: the procedure 26
The oncology population 27
The liver 29
The kidney 34
The pancreas 35
The gallbladder and biliary ducts 36
Other organs and tumors 36
Monitoring angiogenesis 36
Advantages of CEUS 37
Disadvantages of CEUS 37
Summary 39
References 39
Endoscopic Ultrasound in Oncology 43
Key points 43
Introduction 43
EUS equipment 43
EUS in GI oncology 44
Esophageal Cancer 44
Pancreatic Cancer 45
Rectal Cancer 47
Gastric Cancer 47
Liver Masses and Hepatocellular Carcinoma 48
Subepithelial Lesions in the Gastrointestinal Tract 48
EUS in non-GI oncology applications 48
Lung Cancer and Mediastinal Adenopathy (Lymphoma) 48
Renal Masses 49
EUS-based therapeutic interventions in oncology 50
Complications of EUS and EUS-FNA 50
Summary 51
References 51
Therapeutic Applications of Endoscopic Ultrasound 53
Key points 53
Introduction 53
CPN and Celiac Plexus Block 53
EUS-guided Brachytherapy 54
EUS-guided Fiducial Marker Placement 55
Ethanol Ablation 56
EUS-guided Delivery of Antitumor Agents 57
EUS-guided Bile Duct Access 58
EUS-guided Tumor Ablation 59
Pancreatic Pseudocyst and Pelvic Abscess Drainage with the Aid of EUS 60
EUS-guided pancreatic pseudocyst drainage 60
EUS-guided pelvic abscess drainage 60
Summary 62
References 62
Ultrasound Guidance in Tumor Ablation 67
Key points 67
Introduction 67
Principles of radiofrequency ablation 68
Principles of cryoablation 68
General selection criteria 68
Selection criteria for hepatic ablation 70
Selection criteria for renal ablation 71
Selection of imaging modalities 71
Sonoelastography and contrast-enhanced ultrasonography 73
Specifics of ultrasound-guided procedures 73
Alternative methods of ablation 77
Summary 78
References 78
Ultrasound-Guided Biopsy of the Prostate 81
Key points 81
Discussion of problem/clinical presentation 81
Preprocedural evaluation 81
Indications of TRUS-Guided Prostate Biopsy 81
Patient discomfort and anesthesia 82
Patient Preparation 82
Bowel cleansing 82
Antibiotic prophylaxis 83
Anticoagulant avoidance 83
Prebiopsy anesthesia 83
Anatomy 84
Sonographic Anatomy 84
Imaging features 84
Biopsy protocols 84
Technique of TRUS-Guided Prostate Biopsy 84
Systematic biopsy 86
Targeted biopsy 87
Follow-up TRUS-guided prostate biopsy 87
Saturation biopsy 87
Transperineal biopsy 87
Advanced Imaging Techniques 88
Transrectal contrast-enhanced ultrasound-guided biopsy 88
Elastography 88
MR imaging–assisted biopsies 88
Complications of TRUS-Guided Biopsy 90
Pearls, pitfalls, and variants 90
Pathology 90
What the referring physician needs to know 91
Summary 91
References 91
Prostate Cancer Biomarkers 95
Key points 95
Introduction 95
Biomarkers 95
PSA 95
[-2]proPSA and prostate health index 96
4Kscore and Prostarix 96
PCA3 97
TMPRSS2:ERG 97
Summary 97
References 97
Salivary Gland 99
Key points 99
Anatomy of the parotid space 99
Anatomy of the submandibular gland 101
Anatomy of the sublingual gland 101
Clinical presentation of a salivary gland tumor 101
The role of imaging 101
Sonographic technique 102
Salivary gland neoplastic disease 102
Benign tumors 103
Pleomorphic adenomas 103
Warthin tumor (cystadenolymphoma) 104
Oncocytoma 105
Other benign nonepithelial tumors 105
Malignant lesion 105
Mucoepidermoid carcinoma 105
Adenoid cystic carcinoma 106
Metastasis 106
Lymphoma 107
Carcinoma ex pleomorphic adenomas 107
Color flow assessment 107
Tumor mimics 108
Pitfalls 109
Interventional salivary gland ultrasound 109
New developments 110
What the referring clinician needs to know 111
Summary 111
References 111
Index 115