Abstract

A New Look at Mechanisms in Bioenergetics features eight lectures based on the Robbins Lectures given at Pomona College in April 1973. These lectures are based mainly on the author's own laboratory work and are intended for students of biology and biochemistry who want to devote their lives to research.
Lecture 1 presents some of the general lessons learned from research in the field of bioenergetics. It also discusses methods for measuring oxidative phosphorylation and the resolution of soluble multienzyme systems. Lecture 2 explains the biochemical approach to the problem of photophosphorylation. Lecture 3 considers the intersection of oxidative phosphorylation and membranology. Lecture 4 discusses the coupling device and its partial reactions. Lecture 5 focuses on the oxidation chain in mitochondria. Lecture 6 discusses the resolution and reconstitution of oxidative phosphorylation. Lecture 7 examines the reconstitution of ion pumps. Finally, Lecture 8 covers oxidation control in glycolysis; the high aerobic glycolysis of tumor cells; ATPases in tumor cells; and the repair of ion pumps in tumor cells.