Abstract

For students as well as researchers this book describes the exciting new advances in the molecular biology of transport proteins and integrates this information with transport kinetics, function, and regulation. Experimental data are linked with theory.

• Provides an introduction to the properties of transport proteins: channels, carriers, and pumps
• Presents up-to-date information on the structure of transport proteins and on their function and regulation
• Includes introductions to transport kinetics and to the cloning of genes that code transport proteins
• Furnishes a link between the experimental basis of the subject and theoretical model building

"A book that provides a solid foundation for those entering the field at the research level, as well as for more advanced students, is timely. This book fulfils such a role admirably. Even though it addresses a rapidly moving field, this book is not simply a progress report but is complete in itself. It provides, in a clear and comprehensive fashion, the background and framework essential for putting into perspective a rapidly expanding body of information on the molecular basis of channels, carriers, and pumps.

One of the most attractive and important aspects of the book is that it places kinetic and regulatory studies, which often seem boring, irrelevant or incomprehensible, into context, making them readily accessible and emphasizing their importance. It is unusual, at least in my experience, to find a book or article addressing 'pre-molecular biology' aspects of research that is both enjoyable to read and so admirably places such research in the context of current molecular thinking.

I strongly recommend this book to anyone interested in, or needing to gain an understanding of, the basis of membrane transport." --TIPS